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The map label for this gene is lolC [H]

Identifier: 32265817

GI number: 32265817

Start: 315191

End: 316444

Strand: Direct

Name: lolC [H]

Synonym: HH0318

Alternate gene names: 32265817

Gene position: 315191-316444 (Clockwise)

Preceding gene: 161546634

Following gene: 32265818

Centisome position: 17.52

GC content: 36.2

Gene sequence:

>1254_bases
ATGAAGACACTTATTTTTTATCTCTTGCCCCGTTATTTACGTTTTGACAAAACACAACCTTTCATTTCTATCACGGCACT
CTTAGCATTTTTTGGTGTGGGTATTGGCGTTATGGTGCTTTGTGTAGCAATGGCTATTATGAATGGTATGACAAAAGAAT
TTGAACGCAAACTCTCTATTATGAACTATCCTCTAAGCATATATTCTACTACCTATGAGGGTGTAGATGCAAATATACTT
CAGGCACTCAAAGCGCATTTTCCTCAATTTCTTTTTAGTCCTTATTTGCGTTATCAAGCTGTGGGCAAAATAGGCAATAC
AATGAGTGCAGCTATGGTTTTTGGTGTAGATATGCAAGCAGAATCCCAAATCAATGCTGTTGTCAAAAAAGCTTTTAAAA
CTTCTCAAAATTCCGATACGGAATTTAAAAAAAATATTGAATCTTTTATGCAAAAAGAGTTTTCTATTCTTATAGGAAAA
AGTATGGAGGAAAATTTCGGATTAGAATCTGGCGATAAACTTGATTTATTTTTTACCCAACTTGAACCATCAGGATTTAG
CTACACACCTATTAATAAACGTTTTAGTATTGCAGGATTCTTTGAATCTGGTTTGAGAGCGTATGATGAAGCTTATGTAT
ATACAAATTTAAGCGCATTACAAAAGATTCGCCATCTTAATGAGGGCATATATGATGGGATTCACATATACACACCAAAT
CCTATGCAAGATATTCATAGCATTAGCGATTTTCTTAACACACAATTTCCCTATCGCGCTGGAGTTGAGGGCTGGTGGCA
ACAAAATGGCAATTTTTTCTCGGCGTTAGAGCTTGAAAAACGCGCACTTTTTATTGTGCTTATGCTTATCATTGTAATGG
CTGCTCTTAATATCATTAGCTCTTTACTTATGGTTGTAATGAATCGCCGCAAAGAAATTGCTCTGCTCCTCTCGCTTGGA
GCAAGTAGGCAAGAGATTAAAAGTATATTTTTTTGGGTGGGAAATACTATCGGTTTAAGTGGTATAGCGCTTGGGATTAT
TCTCACAGGTATAGCAATGTATGTGCTTGATACTTTCCCCATTATCTCGCTTCCCGCAGATGTATATGGTAGCTCTAAGT
TACCGCTAGACTTATCTTTGATTGACTTCTTGCTTACAATTATAGGGGCAATTTTTATCGTATGCCTTTCCTCTTATTAT
CCTGCGAGAAAAGCTTCCTTAGTAGATACCTTGCAAGTTTTACGCAATGAATAA

Upstream 100 bases:

>100_bases
GAACAAAATTGCACGCAATGACCCTTGTCCTTGCGGTAGTGGCAAAAAATACAAAGTATGCCACGGCAAAAGCGGACCTA
AAAGTGGATTACTTGCATAA

Downstream 100 bases:

>100_bases
TGCAATAGTATCTTTTTAAGAAACTTATAAGTAAATAAATCGTAGCATACAAGGACGTCCTTAAAGTTGGGGGTTAGTTA
TTTTTTAGGAGTTGCTTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKTLIFYLLPRYLRFDKTQPFISITALLAFFGVGIGVMVLCVAMAIMNGMTKEFERKLSIMNYPLSIYSTTYEGVDANIL
QALKAHFPQFLFSPYLRYQAVGKIGNTMSAAMVFGVDMQAESQINAVVKKAFKTSQNSDTEFKKNIESFMQKEFSILIGK
SMEENFGLESGDKLDLFFTQLEPSGFSYTPINKRFSIAGFFESGLRAYDEAYVYTNLSALQKIRHLNEGIYDGIHIYTPN
PMQDIHSISDFLNTQFPYRAGVEGWWQQNGNFFSALELEKRALFIVLMLIIVMAALNIISSLLMVVMNRRKEIALLLSLG
ASRQEIKSIFFWVGNTIGLSGIALGIILTGIAMYVLDTFPIISLPADVYGSSKLPLDLSLIDFLLTIIGAIFIVCLSSYY
PARKASLVDTLQVLRNE

Sequences:

>Translated_417_residues
MKTLIFYLLPRYLRFDKTQPFISITALLAFFGVGIGVMVLCVAMAIMNGMTKEFERKLSIMNYPLSIYSTTYEGVDANIL
QALKAHFPQFLFSPYLRYQAVGKIGNTMSAAMVFGVDMQAESQINAVVKKAFKTSQNSDTEFKKNIESFMQKEFSILIGK
SMEENFGLESGDKLDLFFTQLEPSGFSYTPINKRFSIAGFFESGLRAYDEAYVYTNLSALQKIRHLNEGIYDGIHIYTPN
PMQDIHSISDFLNTQFPYRAGVEGWWQQNGNFFSALELEKRALFIVLMLIIVMAALNIISSLLMVVMNRRKEIALLLSLG
ASRQEIKSIFFWVGNTIGLSGIALGIILTGIAMYVLDTFPIISLPADVYGSSKLPLDLSLIDFLLTIIGAIFIVCLSSYY
PARKASLVDTLQVLRNE
>Mature_417_residues
MKTLIFYLLPRYLRFDKTQPFISITALLAFFGVGIGVMVLCVAMAIMNGMTKEFERKLSIMNYPLSIYSTTYEGVDANIL
QALKAHFPQFLFSPYLRYQAVGKIGNTMSAAMVFGVDMQAESQINAVVKKAFKTSQNSDTEFKKNIESFMQKEFSILIGK
SMEENFGLESGDKLDLFFTQLEPSGFSYTPINKRFSIAGFFESGLRAYDEAYVYTNLSALQKIRHLNEGIYDGIHIYTPN
PMQDIHSISDFLNTQFPYRAGVEGWWQQNGNFFSALELEKRALFIVLMLIIVMAALNIISSLLMVVMNRRKEIALLLSLG
ASRQEIKSIFFWVGNTIGLSGIALGIILTGIAMYVLDTFPIISLPADVYGSSKLPLDLSLIDFLLTIIGAIFIVCLSSYY
PARKASLVDTLQVLRNE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=25.7211538461538, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=22.7817745803357, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46860; Mature: 46860

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLIFYLLPRYLRFDKTQPFISITALLAFFGVGIGVMVLCVAMAIMNGMTKEFERKLSI
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNYPLSIYSTTYEGVDANILQALKAHFPQFLFSPYLRYQAVGKIGNTMSAAMVFGVDMQA
HCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHH
ESQINAVVKKAFKTSQNSDTEFKKNIESFMQKEFSILIGKSMEENFGLESGDKLDLFFTQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEEEE
LEPSGFSYTPINKRFSIAGFFESGLRAYDEAYVYTNLSALQKIRHLNEGIYDGIHIYTPN
ECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCC
PMQDIHSISDFLNTQFPYRAGVEGWWQQNGNFFSALELEKRALFIVLMLIIVMAALNIIS
HHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLMVVMNRRKEIALLLSLGASRQEIKSIFFWVGNTIGLSGIALGIILTGIAMYVLDTFP
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
IISLPADVYGSSKLPLDLSLIDFLLTIIGAIFIVCLSSYYPARKASLVDTLQVLRNE
HHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLIFYLLPRYLRFDKTQPFISITALLAFFGVGIGVMVLCVAMAIMNGMTKEFERKLSI
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNYPLSIYSTTYEGVDANILQALKAHFPQFLFSPYLRYQAVGKIGNTMSAAMVFGVDMQA
HCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHH
ESQINAVVKKAFKTSQNSDTEFKKNIESFMQKEFSILIGKSMEENFGLESGDKLDLFFTQ
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEEEE
LEPSGFSYTPINKRFSIAGFFESGLRAYDEAYVYTNLSALQKIRHLNEGIYDGIHIYTPN
ECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCC
PMQDIHSISDFLNTQFPYRAGVEGWWQQNGNFFSALELEKRALFIVLMLIIVMAALNIIS
HHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLMVVMNRRKEIALLLSLGASRQEIKSIFFWVGNTIGLSGIALGIILTGIAMYVLDTFP
HHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
IISLPADVYGSSKLPLDLSLIDFLLTIIGAIFIVCLSSYYPARKASLVDTLQVLRNE
HHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]