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The map label for this gene is nahA [H]

Identifier: 29350089

GI number: 29350089

Start: 6139160

End: 6140770

Strand: Reverse

Name: nahA [H]

Synonym: BT_4681

Alternate gene names: 29350089

Gene position: 6140770-6139160 (Counterclockwise)

Preceding gene: 29350090

Following gene: 29350088

Centisome position: 98.09

GC content: 43.14

Gene sequence:

>1611_bases
ATGAATACAAAAACATTTACCCCCAAATCGACCATGAAAATTTATACTTGTCTTTGCTTGCTTTTCTTAGCCGATTATCT
GGTTGCCCAGAATAATACTTCGGCATTGTTGCCTATGCCCAATCAGATAACTTCAGTAAAAGGGAAACCCTTTACTGTCC
GTTCCGGAAAAACGGCCATTTATTTGAGTCAGCCGGAGTTGCAGTTCACTGCCAATACGCTGCAAAATATATTATCAGAC
AGAATGCAAGTGGAAATTCCACTTGCTTCCGAATCCGACCGTGCTGATATCCGCTTGTTAATTGACCCTGCAATGGAAGG
AAATGAGCACTATCGCATCGAAATAACTTCCAAAAGGATAACTATCAGCGGAGCTACTGTACGAGCTGTTTATTATGGAG
TTATGACTATGGACCAGCTTCTTTTAGGTGATGTATGCGCCACTACACAAAAGAAAATTTCTCCTGTCTACGTTGATGAT
GCGCCCCGATTCTCTCATCGGGCATTGATGCTCGACCCCGCCCGTCATTTTCTTCCGGTCAATGATGTGAAGTTCTTCAT
TGACCAGATGGCACATTACAAATACAACATACTCCAATTGCATTTGACAGATGACCAGGGATGGAGAGTCGAAATAAAAA
AACATCCTAAACTAGTTGGCAAAGATTATTATACCCAAGAGCAGCTTGCCGAAATCATTCAATATGCTGCCCAACGGAAT
ATCGAGGTCATTCCCGAACTGGATATCCCCGGACACACCGTAGCTATATTAGCAGCTTATCCCGAATTAGGATGTACTCA
TACCGATACGCTGCCTAAGATAGTAGGCAAAACTACGGATTTAATGCTTTGTGCAAATAATCAGAAAGTGTATTCCGTCT
ATCAGGATATCATCAAAGAAATATCTTCTTTGTTTCCATCCGATTATATACATTTAGGAGGCGACGAAGCTGTTATAGAA
AAGAACTGGACTCAATGTACCCGTTGCCAGGCCATGATGAAAGAGTTAGGCTATCAGAAAGCTTCGCAACTCATGATTCC
TTTTTTCAGCCGCATGCTTTCGTTTGTTCAGGAAAATAATAAGACTCCTATGCTTTGGTGCGAACTGGACAATATTTATC
CGCCTGCCAACGACTATCTCTTTCCTTATCCCAAGAACGTAACTTTAGTAAGCTGGCGTGGAGGATTGACACCTACTTGT
CTTGAACTTACCCGAAAACATGGCAATCCGCTTATCATGGCACCGGGTGAGTACGCTTATCTGGATTATCCGCAACTGAA
AGGAGATTTCCCCGAGTTTAACAATTGGGGCATGCCCGTCACCACTTTGGAGAAGTCTTATCAATTCGACCCGGGATATG
GCGTGTCCGCTGAAGATCAAGCCCATATCATAGGAGTTATGGGCACTTTATGGGGAGAAGCTATACGGGATATAAACCGG
GCAACTTATATGGCATACCCGCGCGCTTTCGCACTGGCAGAAGCAGGATGGACACAAATGAAACATCGCAATTGGGAATC
ATTCAAACAACGTCTTTACCCCAATCTGACTAATATGATGAAGAAAGGGGTTTCGGTACGTGTTCCTTTTGAGATAGTTG
ACAGGAAGTAA

Upstream 100 bases:

>100_bases
AAAACAGTGAAAGGGCGTAGCTATCAGCTAAAATACGACAAAGAGAATGGATTAATAAAAATCAAATAATAACATAACAC
TTTAACCTATGTCATCTTAG

Downstream 100 bases:

>100_bases
AATCTCAATTATAAGCCATTTAATATGCTATTTCAACTAAACATGAGATACTAGCTATTTTTAGGGATAGAACATTGATG
AAGCTATTCAAATAGTATAT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MNTKTFTPKSTMKIYTCLCLLFLADYLVAQNNTSALLPMPNQITSVKGKPFTVRSGKTAIYLSQPELQFTANTLQNILSD
RMQVEIPLASESDRADIRLLIDPAMEGNEHYRIEITSKRITISGATVRAVYYGVMTMDQLLLGDVCATTQKKISPVYVDD
APRFSHRALMLDPARHFLPVNDVKFFIDQMAHYKYNILQLHLTDDQGWRVEIKKHPKLVGKDYYTQEQLAEIIQYAAQRN
IEVIPELDIPGHTVAILAAYPELGCTHTDTLPKIVGKTTDLMLCANNQKVYSVYQDIIKEISSLFPSDYIHLGGDEAVIE
KNWTQCTRCQAMMKELGYQKASQLMIPFFSRMLSFVQENNKTPMLWCELDNIYPPANDYLFPYPKNVTLVSWRGGLTPTC
LELTRKHGNPLIMAPGEYAYLDYPQLKGDFPEFNNWGMPVTTLEKSYQFDPGYGVSAEDQAHIIGVMGTLWGEAIRDINR
ATYMAYPRAFALAEAGWTQMKHRNWESFKQRLYPNLTNMMKKGVSVRVPFEIVDRK

Sequences:

>Translated_536_residues
MNTKTFTPKSTMKIYTCLCLLFLADYLVAQNNTSALLPMPNQITSVKGKPFTVRSGKTAIYLSQPELQFTANTLQNILSD
RMQVEIPLASESDRADIRLLIDPAMEGNEHYRIEITSKRITISGATVRAVYYGVMTMDQLLLGDVCATTQKKISPVYVDD
APRFSHRALMLDPARHFLPVNDVKFFIDQMAHYKYNILQLHLTDDQGWRVEIKKHPKLVGKDYYTQEQLAEIIQYAAQRN
IEVIPELDIPGHTVAILAAYPELGCTHTDTLPKIVGKTTDLMLCANNQKVYSVYQDIIKEISSLFPSDYIHLGGDEAVIE
KNWTQCTRCQAMMKELGYQKASQLMIPFFSRMLSFVQENNKTPMLWCELDNIYPPANDYLFPYPKNVTLVSWRGGLTPTC
LELTRKHGNPLIMAPGEYAYLDYPQLKGDFPEFNNWGMPVTTLEKSYQFDPGYGVSAEDQAHIIGVMGTLWGEAIRDINR
ATYMAYPRAFALAEAGWTQMKHRNWESFKQRLYPNLTNMMKKGVSVRVPFEIVDRK
>Mature_536_residues
MNTKTFTPKSTMKIYTCLCLLFLADYLVAQNNTSALLPMPNQITSVKGKPFTVRSGKTAIYLSQPELQFTANTLQNILSD
RMQVEIPLASESDRADIRLLIDPAMEGNEHYRIEITSKRITISGATVRAVYYGVMTMDQLLLGDVCATTQKKISPVYVDD
APRFSHRALMLDPARHFLPVNDVKFFIDQMAHYKYNILQLHLTDDQGWRVEIKKHPKLVGKDYYTQEQLAEIIQYAAQRN
IEVIPELDIPGHTVAILAAYPELGCTHTDTLPKIVGKTTDLMLCANNQKVYSVYQDIIKEISSLFPSDYIHLGGDEAVIE
KNWTQCTRCQAMMKELGYQKASQLMIPFFSRMLSFVQENNKTPMLWCELDNIYPPANDYLFPYPKNVTLVSWRGGLTPTC
LELTRKHGNPLIMAPGEYAYLDYPQLKGDFPEFNNWGMPVTTLEKSYQFDPGYGVSAEDQAHIIGVMGTLWGEAIRDINR
ATYMAYPRAFALAEAGWTQMKHRNWESFKQRLYPNLTNMMKKGVSVRVPFEIVDRK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=460, Percent_Identity=27.3913043478261, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI189181666, Length=439, Percent_Identity=28.0182232346241, Blast_Score=138, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17569815, Length=413, Percent_Identity=25.90799031477, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24657468, Length=465, Percent_Identity=25.3763440860215, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17647501, Length=465, Percent_Identity=25.3763440860215, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281365639, Length=465, Percent_Identity=25.3763440860215, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24657474, Length=465, Percent_Identity=25.3763440860215, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17933586, Length=551, Percent_Identity=23.2304900181488, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45551090, Length=452, Percent_Identity=23.4513274336283, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653074, Length=452, Percent_Identity=23.4513274336283, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 61176; Mature: 61176

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKTFTPKSTMKIYTCLCLLFLADYLVAQNNTSALLPMPNQITSVKGKPFTVRSGKTAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHCCCCCCEEEECCCEEE
YLSQPELQFTANTLQNILSDRMQVEIPLASESDRADIRLLIDPAMEGNEHYRIEITSKRI
EEECCCCEEHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEE
TISGATVRAVYYGVMTMDQLLLGDVCATTQKKISPVYVDDAPRFSHRALMLDPARHFLPV
EEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCHHHCCCH
NDVKFFIDQMAHYKYNILQLHLTDDQGWRVEIKKHPKLVGKDYYTQEQLAEIIQYAAQRN
HHHHHHHHHHHHCEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
IEVIPELDIPGHTVAILAAYPELGCTHTDTLPKIVGKTTDLMLCANNQKVYSVYQDIIKE
CEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
ISSLFPSDYIHLGGDEAVIEKNWTQCTRCQAMMKELGYQKASQLMIPFFSRMLSFVQENN
HHHHCCCCEEEECCCCEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
KTPMLWCELDNIYPPANDYLFPYPKNVTLVSWRGGLTPTCLELTRKHGNPLIMAPGEYAY
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEE
LDYPQLKGDFPEFNNWGMPVTTLEKSYQFDPGYGVSAEDQAHIIGVMGTLWGEAIRDINR
ECCHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
ATYMAYPRAFALAEAGWTQMKHRNWESFKQRLYPNLTNMMKKGVSVRVPFEIVDRK
HHEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCEEEECCEECCCC
>Mature Secondary Structure
MNTKTFTPKSTMKIYTCLCLLFLADYLVAQNNTSALLPMPNQITSVKGKPFTVRSGKTAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHCCCCCCEEEECCCEEE
YLSQPELQFTANTLQNILSDRMQVEIPLASESDRADIRLLIDPAMEGNEHYRIEITSKRI
EEECCCCEEHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEE
TISGATVRAVYYGVMTMDQLLLGDVCATTQKKISPVYVDDAPRFSHRALMLDPARHFLPV
EEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCHHHCCCH
NDVKFFIDQMAHYKYNILQLHLTDDQGWRVEIKKHPKLVGKDYYTQEQLAEIIQYAAQRN
HHHHHHHHHHHHCEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
IEVIPELDIPGHTVAILAAYPELGCTHTDTLPKIVGKTTDLMLCANNQKVYSVYQDIIKE
CEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
ISSLFPSDYIHLGGDEAVIEKNWTQCTRCQAMMKELGYQKASQLMIPFFSRMLSFVQENN
HHHHCCCCEEEECCCCEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
KTPMLWCELDNIYPPANDYLFPYPKNVTLVSWRGGLTPTCLELTRKHGNPLIMAPGEYAY
CCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEE
LDYPQLKGDFPEFNNWGMPVTTLEKSYQFDPGYGVSAEDQAHIIGVMGTLWGEAIRDINR
ECCHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
ATYMAYPRAFALAEAGWTQMKHRNWESFKQRLYPNLTNMMKKGVSVRVPFEIVDRK
HHEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHCCCEEEECCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]