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The map label for this gene is glcK [H]

Identifier: 29350062

GI number: 29350062

Start: 6089786

End: 6090739

Strand: Reverse

Name: glcK [H]

Synonym: BT_4654

Alternate gene names: 29350062

Gene position: 6090739-6089786 (Counterclockwise)

Preceding gene: 29350063

Following gene: 29350061

Centisome position: 97.29

GC content: 47.8

Gene sequence:

>954_bases
ATGGAAAAAGAATACGCTATAGGAATTGATCTTGGCGGGACTTCTGTGAAATACGCTCTTATTGATAATAATGGCGTATT
TCACTTTCAAGGGAAGCTACCGTCGAATGCCGACGTATCAGCCGAAGCTGTCATCGGGCAATTAGTCAAGGCAGTCAATG
AAGTGAAAACCTTTGCCGAAGCAAAGAGGTATACAATAGCCGGTATCGGGATAGGGACGCCGGGAATTGTCGATTGTACG
AATCGTATCGTATTGGGAGGTGCGGAGAATATTCAAGGCTGGGAAAATCTGAAACTGGCAGACCGGATGGAAAAAGAGAC
CGGACTTCCTACCCAACTGGGAAATGACGCTAATCTGATGGGACTTGGCGAAACGATGTACGGAGCCGGAAACGGAGCCA
CTCATGTGGTCTTTCTGACTGTAGGAACCGGTATCGGTGGCGCAGTCATAATTGACGGCAAACTGTTTAACGGATACGCC
AATAGAGGTACTGAATTGGGACATGTCCCCTTGATAGCTAATGGTGAACCTTGCGCCTGCGGTTCAATAGGATGCCTTGA
ACATTATGCTTCCACTGCCGCACTGGTCCGTCGTTTCAGCAAACGGATAGCCGAAGCCGGCATCTCTTATCCGAATGAAG
AAATAAACGGAGAATTGATCGTCCGTCTCTATAAACAAGGAGATAAGATTGCGGCTGAGTCGCTGAACGAACATTGTGAT
TTCCTCGGTCACGGCATTGCCGGATTTATTAATATCTTCAGCCCTCAAAGAGTCGTTATCGGCGGAGGACTGTCCGAAGC
CGGAGACTTTTATATTCAGAAAGTAAGTGAGAAAGCCCTTCGCTATGCCATCCCCGACTGTGCCGTGAACACGGAAATCA
TGGCAGCCTCTTTAGGCAACAAAGCCGGAAGTATCGGTGCCGCCTCCCTCTTTTTAAATAGAAAACCGAATTAA

Upstream 100 bases:

>100_bases
AAGCTGTTGGCACTGCTATGCCAAGCCTTTGGCACAAGCGTGCCAATACGGTGGCACAAGCATGGCACAGTATAAACGAA
TTTAAAACATACCTAGTTAT

Downstream 100 bases:

>100_bases
ATGAAGAGCAGAAAACCTTCTCAACTTATTTAAGATTATGAAGAAAAATCTAGGAATGCTGGCGCTGATTATGGCGTTCT
GGTTCACTATCTCGTTTATT

Product: ROK family transcriptional repressor

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEKEYAIGIDLGGTSVKYALIDNNGVFHFQGKLPSNADVSAEAVIGQLVKAVNEVKTFAEAKRYTIAGIGIGTPGIVDCT
NRIVLGGAENIQGWENLKLADRMEKETGLPTQLGNDANLMGLGETMYGAGNGATHVVFLTVGTGIGGAVIIDGKLFNGYA
NRGTELGHVPLIANGEPCACGSIGCLEHYASTAALVRRFSKRIAEAGISYPNEEINGELIVRLYKQGDKIAAESLNEHCD
FLGHGIAGFINIFSPQRVVIGGGLSEAGDFYIQKVSEKALRYAIPDCAVNTEIMAASLGNKAGSIGAASLFLNRKPN

Sequences:

>Translated_317_residues
MEKEYAIGIDLGGTSVKYALIDNNGVFHFQGKLPSNADVSAEAVIGQLVKAVNEVKTFAEAKRYTIAGIGIGTPGIVDCT
NRIVLGGAENIQGWENLKLADRMEKETGLPTQLGNDANLMGLGETMYGAGNGATHVVFLTVGTGIGGAVIIDGKLFNGYA
NRGTELGHVPLIANGEPCACGSIGCLEHYASTAALVRRFSKRIAEAGISYPNEEINGELIVRLYKQGDKIAAESLNEHCD
FLGHGIAGFINIFSPQRVVIGGGLSEAGDFYIQKVSEKALRYAIPDCAVNTEIMAASLGNKAGSIGAASLFLNRKPN
>Mature_317_residues
MEKEYAIGIDLGGTSVKYALIDNNGVFHFQGKLPSNADVSAEAVIGQLVKAVNEVKTFAEAKRYTIAGIGIGTPGIVDCT
NRIVLGGAENIQGWENLKLADRMEKETGLPTQLGNDANLMGLGETMYGAGNGATHVVFLTVGTGIGGAVIIDGKLFNGYA
NRGTELGHVPLIANGEPCACGSIGCLEHYASTAALVRRFSKRIAEAGISYPNEEINGELIVRLYKQGDKIAAESLNEHCD
FLGHGIAGFINIFSPQRVVIGGGLSEAGDFYIQKVSEKALRYAIPDCAVNTEIMAASLGNKAGSIGAASLFLNRKPN

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=285, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI298566325, Length=285, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4885285, Length=285, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI190014632, Length=285, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1787878, Length=269, Percent_Identity=24.907063197026, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI87081733, Length=320, Percent_Identity=27.1875, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787363, Length=317, Percent_Identity=26.813880126183, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786891, Length=302, Percent_Identity=27.1523178807947, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790522, Length=325, Percent_Identity=26.7692307692308, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082230, Length=262, Percent_Identity=30.5343511450382, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33321; Mature: 33321

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEYAIGIDLGGTSVKYALIDNNGVFHFQGKLPSNADVSAEAVIGQLVKAVNEVKTFAE
CCCCEEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AKRYTIAGIGIGTPGIVDCTNRIVLGGAENIQGWENLKLADRMEKETGLPTQLGNDANLM
HCCEEEEEECCCCCCCEECCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEE
GLGETMYGAGNGATHVVFLTVGTGIGGAVIIDGKLFNGYANRGTELGHVPLIANGEPCAC
ECCHHHCCCCCCCEEEEEEEECCCCCCEEEECCEEECCCCCCCCCCCCEEEEECCCCCCC
GSIGCLEHYASTAALVRRFSKRIAEAGISYPNEEINGELIVRLYKQGDKIAAESLNEHCD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
FLGHGIAGFINIFSPQRVVIGGGLSEAGDFYIQKVSEKALRYAIPDCAVNTEIMAASLGN
HHHCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
KAGSIGAASLFLNRKPN
CCCCCEEEEEEEECCCC
>Mature Secondary Structure
MEKEYAIGIDLGGTSVKYALIDNNGVFHFQGKLPSNADVSAEAVIGQLVKAVNEVKTFAE
CCCCEEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AKRYTIAGIGIGTPGIVDCTNRIVLGGAENIQGWENLKLADRMEKETGLPTQLGNDANLM
HCCEEEEEECCCCCCCEECCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEE
GLGETMYGAGNGATHVVFLTVGTGIGGAVIIDGKLFNGYANRGTELGHVPLIANGEPCAC
ECCHHHCCCCCCCEEEEEEEECCCCCCEEEECCEEECCCCCCCCCCCCEEEEECCCCCCC
GSIGCLEHYASTAALVRRFSKRIAEAGISYPNEEINGELIVRLYKQGDKIAAESLNEHCD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
FLGHGIAGFINIFSPQRVVIGGGLSEAGDFYIQKVSEKALRYAIPDCAVNTEIMAASLGN
HHHCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
KAGSIGAASLFLNRKPN
CCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]