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The map label for this gene is sglT [H]

Identifier: 29348222

GI number: 29348222

Start: 3494224

End: 3495693

Strand: Reverse

Name: sglT [H]

Synonym: BT_2813

Alternate gene names: 29348222

Gene position: 3495693-3494224 (Counterclockwise)

Preceding gene: 29348223

Following gene: 29348221

Centisome position: 55.84

GC content: 45.44

Gene sequence:

>1470_bases
ATGTCTATTCTCGACATTATTATCTTTTTATTCTTCACGGGGGGAGTTGTTGTCTTCGGCTGCTCTTTCTTCAACAAGAA
ACGTTCGTCGGAGGAATTTACTTCGGCAGGACGTTCCCTTCCGGGTTGGGTTGTGGGAATGTCTATTTTCGCAACGTATG
TAAGTAGTATCAGTTATCTGGCTTATCCGGGCAAGGCCTATATGTCCGATTGGAATGCTTTTGTATTCAGCTTGTCCATT
CCGATAGCCTCGTATTTTGCTGCTAAATACTTTGTACCCTTTTATCGTTCTATCGGAAGCGTATCGGCTTACAGTTTTCT
GGAAGAACGCTTTGGTCCCTGGGCGCGTGTATATGCGTCATCGTGTTATCTTTTGACGCAGGTTGCCCGGATGGGGTCTA
TTCTGTATCTGCTCGCATTGCCTATGAATGCCCTGCTGGGATGGGATATTAAGATGATTATCGCAGTAACCAGCGTTGCC
ATTATTGCCTATTCAATGCTGGGTGGTCTGAAAGCTGTGATATGGACGGAGGCGATTCAGGGATTTATTCTGATTGGTGG
TGCGATAGCCTGCCTTTGTGTGCTGATGTTTAAAATGCCCGAAGGGCCTGCGCAGGTATTTCAGATAGCCATTACTGACC
AGAAATTCAGTTTGGGAAGTTTCGGCAGCAGTCTGACCGAGTCTACTTTCTGGGTATGCCTTATTTACGGTATATTTATC
AATCTACAGAATTATGGTATTGATCAGAACTACGTACAGCGTTATTTGACGGCAAAGAGTGATAAACAGGCTAAGTTCTC
CGCTCTCTTCGGAGGTTATTTGTTTATTCCGGTTTCTGCAGTGTTCTTTATGATAGGTACGGCATTGTATGCATATTACA
AGACGTTTCCGGAACTGCTTCCGGCAGGGGTCGAGGGGGACGCGGTCTTTCCCTATTTTATTGTACATGCGCTTCCGACC
GGACTTACCGGATTATTGATTGCCTCCATTTTCGCGGCGGGAATGAGTACGGTGGCTACAAGCATTACAAGTTCGGCTAC
TATCATTCTGACGGACTATTATGCCCGTTATATAAATAAGAGACCGACAGAAAAACAATCGGTGAGAGCCTTGTATGTTT
CGAATGTACTGATCGGAATAATCGGTATTTTCGTAGCGCTGGCATTTCTGAACGTAGAGAGTGCGCTGGATGCCTGGTGG
GCTTTGTCCTCCATCTTCAGCGGTGGTATGCTGGGACTCTTCCTGCTGGGGTATATTTCAAAGAAGGCGCGGAATGTTGA
CGCCGTTTTGGGAGTGATCTGTGGCATTATCGTTGTCGTCTGGATGAGCTTGTCTCCTATCTTCTTTAAAGATGGTTTTA
TGAGCGAATATGCAAGCCCGTTTCATGCTAACCTGACTATTGTCTTCGGAACCATTGTTATCTTTTTGGCAGGCTTTCTC
AGTATGCGTTTACTGAAAACAAAGAAGTAG

Upstream 100 bases:

>100_bases
TAAGTTCGAACAACGGGAAAGAGGAAAAATATGGAAGGCACTTCAAAATTTGGGAGTTGATGTAGTGCTCAGGTAATTAA
TCAAGAAAAAATGAACGGCT

Downstream 100 bases:

>100_bases
AAGAAGGCAGCTTCACTGGCAGGCATATTGGTTTCATCTATTATCCGATAGAATTATTCGATTGGACTTTTTTTGCAAAG
GCGGGGTTTCCGCCTTTATC

Product: sodium-dependent multivitamin transporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSILDIIIFLFFTGGVVVFGCSFFNKKRSSEEFTSAGRSLPGWVVGMSIFATYVSSISYLAYPGKAYMSDWNAFVFSLSI
PIASYFAAKYFVPFYRSIGSVSAYSFLEERFGPWARVYASSCYLLTQVARMGSILYLLALPMNALLGWDIKMIIAVTSVA
IIAYSMLGGLKAVIWTEAIQGFILIGGAIACLCVLMFKMPEGPAQVFQIAITDQKFSLGSFGSSLTESTFWVCLIYGIFI
NLQNYGIDQNYVQRYLTAKSDKQAKFSALFGGYLFIPVSAVFFMIGTALYAYYKTFPELLPAGVEGDAVFPYFIVHALPT
GLTGLLIASIFAAGMSTVATSITSSATIILTDYYARYINKRPTEKQSVRALYVSNVLIGIIGIFVALAFLNVESALDAWW
ALSSIFSGGMLGLFLLGYISKKARNVDAVLGVICGIIVVVWMSLSPIFFKDGFMSEYASPFHANLTIVFGTIVIFLAGFL
SMRLLKTKK

Sequences:

>Translated_489_residues
MSILDIIIFLFFTGGVVVFGCSFFNKKRSSEEFTSAGRSLPGWVVGMSIFATYVSSISYLAYPGKAYMSDWNAFVFSLSI
PIASYFAAKYFVPFYRSIGSVSAYSFLEERFGPWARVYASSCYLLTQVARMGSILYLLALPMNALLGWDIKMIIAVTSVA
IIAYSMLGGLKAVIWTEAIQGFILIGGAIACLCVLMFKMPEGPAQVFQIAITDQKFSLGSFGSSLTESTFWVCLIYGIFI
NLQNYGIDQNYVQRYLTAKSDKQAKFSALFGGYLFIPVSAVFFMIGTALYAYYKTFPELLPAGVEGDAVFPYFIVHALPT
GLTGLLIASIFAAGMSTVATSITSSATIILTDYYARYINKRPTEKQSVRALYVSNVLIGIIGIFVALAFLNVESALDAWW
ALSSIFSGGMLGLFLLGYISKKARNVDAVLGVICGIIVVVWMSLSPIFFKDGFMSEYASPFHANLTIVFGTIVIFLAGFL
SMRLLKTKK
>Mature_488_residues
SILDIIIFLFFTGGVVVFGCSFFNKKRSSEEFTSAGRSLPGWVVGMSIFATYVSSISYLAYPGKAYMSDWNAFVFSLSIP
IASYFAAKYFVPFYRSIGSVSAYSFLEERFGPWARVYASSCYLLTQVARMGSILYLLALPMNALLGWDIKMIIAVTSVAI
IAYSMLGGLKAVIWTEAIQGFILIGGAIACLCVLMFKMPEGPAQVFQIAITDQKFSLGSFGSSLTESTFWVCLIYGIFIN
LQNYGIDQNYVQRYLTAKSDKQAKFSALFGGYLFIPVSAVFFMIGTALYAYYKTFPELLPAGVEGDAVFPYFIVHALPTG
LTGLLIASIFAAGMSTVATSITSSATIILTDYYARYINKRPTEKQSVRALYVSNVLIGIIGIFVALAFLNVESALDAWWA
LSSIFSGGMLGLFLLGYISKKARNVDAVLGVICGIIVVVWMSLSPIFFKDGFMSEYASPFHANLTIVFGTIVIFLAGFLS
MRLLKTKK

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI157671931, Length=453, Percent_Identity=28.6975717439294, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI256985183, Length=431, Percent_Identity=28.538283062645, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI167466278, Length=450, Percent_Identity=27.5555555555556, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI4507035, Length=399, Percent_Identity=27.5689223057644, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI206597483, Length=445, Percent_Identity=26.9662921348315, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4507031, Length=377, Percent_Identity=27.3209549071618, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI206597487, Length=383, Percent_Identity=27.6762402088773, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI109659836, Length=486, Percent_Identity=26.3374485596708, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4507033, Length=377, Percent_Identity=26.525198938992, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI109659839, Length=496, Percent_Identity=25.6048387096774, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI17941285, Length=373, Percent_Identity=27.6139410187668, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI14140236, Length=443, Percent_Identity=24.1534988713318, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110835708, Length=406, Percent_Identity=24.1379310344828, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790113, Length=452, Percent_Identity=25, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082237, Length=374, Percent_Identity=24.331550802139, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790503, Length=409, Percent_Identity=23.2273838630807, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533094, Length=409, Percent_Identity=24.6943765281174, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32566512, Length=390, Percent_Identity=23.3333333333333, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115533096, Length=300, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573698, Length=455, Percent_Identity=27.6923076923077, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24640370, Length=417, Percent_Identity=26.378896882494, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24645928, Length=446, Percent_Identity=25.3363228699552, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24651739, Length=462, Percent_Identity=25.7575757575758, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI221459586, Length=445, Percent_Identity=26.2921348314607, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI221459588, Length=442, Percent_Identity=25.3393665158371, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI221459584, Length=436, Percent_Identity=26.1467889908257, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24651741, Length=422, Percent_Identity=24.8815165876777, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281362918, Length=467, Percent_Identity=25.2676659528908, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24641117, Length=426, Percent_Identity=27.9342723004695, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19920916, Length=438, Percent_Identity=25.3424657534247, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281364280, Length=447, Percent_Identity=24.8322147651007, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI221379702, Length=421, Percent_Identity=25.8907363420428, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28574994, Length=425, Percent_Identity=24.4705882352941, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI161076631, Length=437, Percent_Identity=24.2562929061785, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24650192, Length=439, Percent_Identity=23.9179954441913, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281362054, Length=437, Percent_Identity=24.4851258581236, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281362052, Length=437, Percent_Identity=24.4851258581236, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI281362050, Length=437, Percent_Identity=24.4851258581236, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24648056, Length=437, Percent_Identity=24.4851258581236, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356827, Length=437, Percent_Identity=24.4851258581236, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI221459582, Length=436, Percent_Identity=25.4587155963303, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53627; Mature: 53496

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILDIIIFLFFTGGVVVFGCSFFNKKRSSEEFTSAGRSLPGWVVGMSIFATYVSSISYL
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AYPGKAYMSDWNAFVFSLSIPIASYFAAKYFVPFYRSIGSVSAYSFLEERFGPWARVYAS
CCCCHHHHCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHH
SCYLLTQVARMGSILYLLALPMNALLGWDIKMIIAVTSVAIIAYSMLGGLKAVIWTEAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFILIGGAIACLCVLMFKMPEGPAQVFQIAITDQKFSLGSFGSSLTESTFWVCLIYGIFI
HHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
NLQNYGIDQNYVQRYLTAKSDKQAKFSALFGGYLFIPVSAVFFMIGTALYAYYKTFPELL
HHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAGVEGDAVFPYFIVHALPTGLTGLLIASIFAAGMSTVATSITSSATIILTDYYARYINK
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCC
RPTEKQSVRALYVSNVLIGIIGIFVALAFLNVESALDAWWALSSIFSGGMLGLFLLGYIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KKARNVDAVLGVICGIIVVVWMSLSPIFFKDGFMSEYASPFHANLTIVFGTIVIFLAGFL
HHHCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SMRLLKTKK
HHHHHHCCC
>Mature Secondary Structure 
SILDIIIFLFFTGGVVVFGCSFFNKKRSSEEFTSAGRSLPGWVVGMSIFATYVSSISYL
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AYPGKAYMSDWNAFVFSLSIPIASYFAAKYFVPFYRSIGSVSAYSFLEERFGPWARVYAS
CCCCHHHHCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHH
SCYLLTQVARMGSILYLLALPMNALLGWDIKMIIAVTSVAIIAYSMLGGLKAVIWTEAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFILIGGAIACLCVLMFKMPEGPAQVFQIAITDQKFSLGSFGSSLTESTFWVCLIYGIFI
HHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
NLQNYGIDQNYVQRYLTAKSDKQAKFSALFGGYLFIPVSAVFFMIGTALYAYYKTFPELL
HHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAGVEGDAVFPYFIVHALPTGLTGLLIASIFAAGMSTVATSITSSATIILTDYYARYINK
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCC
RPTEKQSVRALYVSNVLIGIIGIFVALAFLNVESALDAWWALSSIFSGGMLGLFLLGYIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KKARNVDAVLGVICGIIVVVWMSLSPIFFKDGFMSEYASPFHANLTIVFGTIVIFLAGFL
HHHCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHH
SMRLLKTKK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]