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The map label for this gene is ahpC [H]

Identifier: 29348221

GI number: 29348221

Start: 3493475

End: 3494041

Strand: Reverse

Name: ahpC [H]

Synonym: BT_2812

Alternate gene names: 29348221

Gene position: 3494041-3493475 (Counterclockwise)

Preceding gene: 29348222

Following gene: 29348220

Centisome position: 55.81

GC content: 45.5

Gene sequence:

>567_bases
ATGGAACCAATTTTAAATTCTCAACTTCCTGAATTCAGTGTTCAGGCTTTTCAAAACGGAGCTTTCAAGACAGTAACCAA
CAACGACCTGAAAGGTAAATGGGCAATCCTTTTCTTCTACCCTGCCGACTTTACATTTGTATGTCCGACAGAATTGGTAG
ACATGGCTGACAAATATGCTCAGTTCCAGGAAATGGGTGTGGAAATCTACTCGGTAAGTACTGACTCGCATTTCGTACAC
AAAGCCTGGCATGATGCTTCCGAAAGTATCCGTAAGATCAAATACCCGATGCTGGCAGACCCGACAGGCGCTTTGAGCCG
TGCACTGGGTGTATATATCGAAGAAGAAGGTATGGCTTACCGCGGAACATTCGTCGTAAACCCGGAAGGAAAGATTAAAG
TGGTGGAACTGAATGATAACAATATTGGTCGTGACGCCAGCGAATTACTTCGCAAAGTAGAAGCCGCACAGTTTGTGGCT
ACTCACGACGGAGAAGTTTGCCCGGCTAAATGGAAGAAGGGCGAATCTACTCTGAAGCCAAGCATTGACCTTGTCGGTAA
GATTTGA

Upstream 100 bases:

>100_bases
GGGGTTTCCGCCTTTATCTTTGCATCAGAAACAAAAAACAAAACGATGTTTCTGATGTTATAAGTCAAATCAATTAATAA
CAATAAAAGCAATAAAGAGT

Downstream 100 bases:

>100_bases
TAGATCTTGATAATGTGTGTGAAGGGCCGGTAACGGAGACGCTGCCGGCCCTTCTTTTAAAAGAATGAAAGGAGAAAGAG
AGATGTTAGAACCTGCATTA

Product: alkyl hydroperoxide reductase C22 protein

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MEPILNSQLPEFSVQAFQNGAFKTVTNNDLKGKWAILFFYPADFTFVCPTELVDMADKYAQFQEMGVEIYSVSTDSHFVH
KAWHDASESIRKIKYPMLADPTGALSRALGVYIEEEGMAYRGTFVVNPEGKIKVVELNDNNIGRDASELLRKVEAAQFVA
THDGEVCPAKWKKGESTLKPSIDLVGKI

Sequences:

>Translated_188_residues
MEPILNSQLPEFSVQAFQNGAFKTVTNNDLKGKWAILFFYPADFTFVCPTELVDMADKYAQFQEMGVEIYSVSTDSHFVH
KAWHDASESIRKIKYPMLADPTGALSRALGVYIEEEGMAYRGTFVVNPEGKIKVVELNDNNIGRDASELLRKVEAAQFVA
THDGEVCPAKWKKGESTLKPSIDLVGKI
>Mature_188_residues
MEPILNSQLPEFSVQAFQNGAFKTVTNNDLKGKWAILFFYPADFTFVCPTELVDMADKYAQFQEMGVEIYSVSTDSHFVH
KAWHDASESIRKIKYPMLADPTGALSRALGVYIEEEGMAYRGTFVVNPEGKIKVVELNDNNIGRDASELLRKVEAAQFVA
THDGEVCPAKWKKGESTLKPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=45.8100558659218, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=44.5054945054945, Blast_Score=165, Evalue=2e-41,
Organism=Homo sapiens, GI32189392, Length=177, Percent_Identity=44.0677966101695, Blast_Score=165, Evalue=3e-41,
Organism=Homo sapiens, GI4505591, Length=177, Percent_Identity=38.4180790960452, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI32455266, Length=177, Percent_Identity=38.4180790960452, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI32455264, Length=177, Percent_Identity=38.4180790960452, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI5453549, Length=182, Percent_Identity=39.5604395604396, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI33188454, Length=76, Percent_Identity=48.6842105263158, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI4758638, Length=161, Percent_Identity=32.9192546583851, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786822, Length=185, Percent_Identity=60, Blast_Score=254, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI193204376, Length=176, Percent_Identity=42.6136363636364, Blast_Score=159, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI32565831, Length=176, Percent_Identity=42.6136363636364, Blast_Score=159, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=39.6648044692737, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25153706, Length=193, Percent_Identity=27.979274611399, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=39.010989010989, Blast_Score=141, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=37.5690607734807, Blast_Score=138, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=28.2208588957055, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=39.247311827957, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17738015, Length=179, Percent_Identity=39.6648044692737, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI17157991, Length=179, Percent_Identity=39.6648044692737, Blast_Score=150, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24641739, Length=179, Percent_Identity=39.6648044692737, Blast_Score=150, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=38.121546961326, Blast_Score=149, Evalue=9e-37,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=38.121546961326, Blast_Score=149, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=34.4155844155844, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24652436, Length=156, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20997; Mature: 20997

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPILNSQLPEFSVQAFQNGAFKTVTNNDLKGKWAILFFYPADFTFVCPTELVDMADKYA
CCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEEEEECCCEEEECHHHHHHHHHHHH
QFQEMGVEIYSVSTDSHFVHKAWHDASESIRKIKYPMLADPTGALSRALGVYIEEEGMAY
HHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCEEECCCCCEE
RGTFVVNPEGKIKVVELNDNNIGRDASELLRKVEAAQFVATHDGEVCPAKWKKGESTLKP
ECEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCC
SIDLVGKI
CCEEECCC
>Mature Secondary Structure
MEPILNSQLPEFSVQAFQNGAFKTVTNNDLKGKWAILFFYPADFTFVCPTELVDMADKYA
CCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEEEEECCCEEEECHHHHHHHHHHHH
QFQEMGVEIYSVSTDSHFVHKAWHDASESIRKIKYPMLADPTGALSRALGVYIEEEGMAY
HHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCEEECCCCCEE
RGTFVVNPEGKIKVVELNDNNIGRDASELLRKVEAAQFVATHDGEVCPAKWKKGESTLKP
ECEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCC
SIDLVGKI
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]