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The map label for this gene is evgS [H]

Identifier: 29348038

GI number: 29348038

Start: 3277939

End: 3281976

Strand: Reverse

Name: evgS [H]

Synonym: BT_2628

Alternate gene names: 29348038

Gene position: 3281976-3277939 (Counterclockwise)

Preceding gene: 29348044

Following gene: 29348037

Centisome position: 52.42

GC content: 41.06

Gene sequence:

>4038_bases
ATGGGAAAACAGTCGGTTTTTATTCTATTCTTTTTTCTTAATCTGTTGATACATAACGCTTATGCTTATAATTTGAAGCA
AGTTGCAGATAAAGAGTATATGTCTAATAGTTCGATTACATCTCTGTGCCAGGATGAGCGTGGATTGATGTGGATCGGGA
CCTGCGACGGACTGAATATTTATGATGGACAGGAGATTGAGGAATTTAAGACTCGTGACAAGGAGGATTACTTATCTGGT
AATCTGATTGACAATATTGTGTATACGGGCGAAGATATTTACTGGATTCAAACCTACTATGGGTTGAACCGTTTGAACCG
GAAAACCAATACAATCACTCACTATAATGAATTTCAGAAACTCTTCTTTATGAATAAGGATAGTCATGGCAATCTGTTCA
TTATCCAGGATAGTAACTGCATCTATTATTATCATAAAAAAGAAGGAGTCTTCAAGAAAATCAATATCACGGGAATCCCG
ATTTCCGATATCGTAAACTTCTTTATCGATGGTAACAACCGGATGTGGGTAGTCATGAAAGGATACAACCGCTGTTATGA
CATACAGCAGGAAGCCGCATCGGGAGATATCACCCTGTTACCCCAGAAAACAAACCTGATTTATCAGACTTCCTTGATTT
ATTGTTTCAATGACGAGCAATCTCTTTATTACATAGACAAGGAATTTAATTTTTATGCTTTCCATATTCCGACCCAGAAG
AATGAATTTATTGCCAATCTGGGTAAGGAAATACAGGAACGTGGCAAAATTTCGTCCATCGTTCATTATCATAACAGCTA
TTTTGTGGGCTTTTTGATGGATGGTATTCTCCTGTTGGAGAAACAGAAGGAGACGGATCATTATCAAATTCAGTCGTTAC
CTATCAACAGCGGTGTATTCTGTCTCAAGAAAGACCGTTTTCAGGATATTGTCTGGATTGGTACTGACGGGCAGGGCGTT
TATCTTTATTCGAACCCGCTTTATTCTATCAAATCAATGGTGCTTAGCAATTACACCGAGAAAATAGAACGCCCCGTGCG
TGCCATCTATCTTGATGATGAACGTACTTTCTGGGTGGGAACTAAAGGAAACGGAATTCTTAAAATCTATGATTACGAAT
TCGATAAAAACATCTCCGACTGCCGGGCAGAGGTGTTGACTACCTCTAATAGTGCTTTGAGTAGTAATGCCGTTTATTGT
TTTGCCAAGAGCCACCGGAATTTGCTTTGGATAGGAGACGAAGAAGGATTAACTTATTATTCATATCGGGAAAAACGTAT
TAAGAGTATACCGATACGGATCGGTAACGAAGATTTTAAATACATCCATGGCATTTACGAAACAGCAGATTCCGAACTGT
GGCTGGCGAGTGTCGGCATGGGAGTGGTGAAGGCTCGTATTGCCGGAACACCGGACAATCCGGTGATTGTGGATGCGCAA
CGTTACGTCATCAATGACGGTGAACTGGGATCGAACTATTTCTTTACTATTTATGCAGAGAATGAAGCCAACTTGTTGTT
TGGTAATAAAGGATATGGGGTGTTCCGTTATAACGAAACGACGAACGGCCTGGAACCGGTGTCTACTCATAAATACGAAA
ACATGACCCTGAATAATATTCTCGCCATCAGTAAAGACAGCAGCAATAACTATCTTTTTGGAACGAGCTACGGATTGATA
AAGTACACTTCGGAAACTTCTTATCAGCTCTTCAATGCTAAGAATGGTTTCCTGAATAATACCATTCATGCAATTCTTAG
AAACTCGTCCGACAACTTCTGGTTGAGCACTAATCTCGGATTAATCAATTTCGATACGAAACGGAATGTCTTTCGTTCGT
ATGGCTTTGGAGATGGTTTAAAAGTGGTAGAGTTTAGTGACGGTGCCGCTTTTCGGGATTCCCGGACTGGTACTCTGTTC
TTTGGCGGAATCAATGGAGTCGTAGCTATCCGGGCGGATGGCCGTCCGGAGCAGCTTTATATGCCTCCTGTTTATTTTGA
TAAGCTGTCTATCTTCGGTGAACAATACAATCTGGGCGAATTTCTCACCCGGAAAAAAGAAACTGAAGTCTTGAATTTGC
AGTATGACCAGAATTTCTTTTCTGTTTCATTTGCCTCTGTGGATTATCTGAATGGTAATAACTGTACCTATTTTTATAAA
CTGAAAGGATTGAGTGACCAATGGGTAAACAATGGTTCGGAAAGCGGAGTCTCTTTTACGAATATGGCTCCCGGCGAATA
TACCTTACTGGTGAAATATTACAATAGTGTTTTTGATAAAGAGAGTGATGTCTATTCCCTGGTCATTCGTATAGGCGATC
CGTGGTATGCTTCCTGGTGGGCTTATTTGATTTATGCCTTCTGTCTGCTTTTACTGGCAGCCTTACTGATACGTTCCTTT
ATCCTGCGCTCCAAACGTAAAAAGCAGGAATTGCTGAACGAGATAGAGAAACGCCATCAAAAGAATGTCTTTGAGTCCAA
ACTTCGTTTCTTTACTAATATCGCACATGAATTTTGTACTCCGCTGACTTTGATTTATAGTCCTTGCGGACGAATCCTTT
CATCGAAAGGACTTAGTAAATTTGTCGTAGACTACGTACAGATGATTCAGACGAATGCGGAGCGTCTCAACAACCTGATT
CATGAATTGATCGAATTCCGTCGGATTGAAACGGGAAACAGGGAAGTACGGATTGAGTCATTGAATGTGTCTTCCATTGT
GAAAGGAATAGCCAAAACGTTTGTAGAAATGGCTAAATCCAGAAACATCACTTTCTTGAGCAAGATACCCGAGCAGGTGA
TGTGGAACTCGGACAAAGGATTCCTGAATACAATTATTATTAATCTGATTTCTAATGCCTTTAAATATACTCCCGACGGA
CAAAGTATCAAGATTGAAGTGGATACGAGCGGGGAAAACATGCTGACTCTTCGTGTAGCGAATGAAGGAAGTACCATCAA
GGAAAAGGATTTTCAGTATATTTTTAATCGGTATGCCATTTTGGATAATTTCGAGAATCAGGATGAAAAGAACTTTTCAC
GGAACGGACTGGGACTAGCCATCTCTTATAATATGGCAAAGTTGCTGAATGGTACGTTGAAAGTGGAAAATACTCCTGAC
GGATGGGTGATGTTTACACTAACCTTGCCGGTCGTGGAACTGACTACCGGAGTGGCGGAAACCAAGCGGCTCACAGCGGA
ATACATCCCTAAGATAGATACTCAATCGATACTGAAACTTCCCCAGTATGAGTTTGATAAGATGCGTCCTACGCTTTTGG
TTGTCGATGATGAAATCGAAATGCTATGGTTTATTGGAGAAATCTTCTCGGCTGACTTCAATGTGGTAACCTTGCAAGAT
CCCGAACGGCTGGATCAGGTGATGAATGAGGTTTATCCGAATGTGATTATCTGTGATGTCATGATGCCGGGAATGGGTGG
CATTGAACTGACCAGGCGGATCAAATCGGTGAAAGAGACGGCGCATATTCCTATTATTGTGGTTTCCGGACGGCACGAGA
TGGAACAACAGATGGAGGCTCTTTCTGCCGGTGCGGAAATGTATATCACGAAACCGTTTAGTGCAGAGTACCTTCGTATT
TCTGTCTGTCAGGTGATAGAACGGAAAGAGGTGTTGAAAAATTATTTCAGTTCGCCGATCAGTTCTTTTGAAAAGTCGGA
TGGAAAGTTAACGCACAAAGAGTCGAAGAAGTTCCTACAATCGGTTTTGAAGATAATCAATGATAATATAACAAACAAGG
ATTTAACGCCGCGTTATATCGCCGATCGGCTGGCAATCAGTCCCCGGAGTCTCTATCGGAAGATGGAAGAGATAGGAGAG
GACAGTCCGACGGATTTGATAAAGGAATGTCGTTTGCATATAGCAAAAGATTTATTGCTGACGACGAAAAAGACGATTGA
TGAAATTGTATTCGATTCAGGATTCTCGAATAAAGTAACTTTCTTCAAGGTGTTCCGTGAAAAGTATGAATGTACGCCAA
AAGAGTTTCGACAAAAACATTTAGCGGAAGTGCAGTAA

Upstream 100 bases:

>100_bases
CTACTCTGGCACGGAGCTTTACTTATATTCCGGCCAAAAAAAAGCTCGGAATGTTTTTTTGTTTACCTTTGTCATATAGC
AAATCTAAGAATAATACACT

Downstream 100 bases:

>100_bases
TAAATTTGAAATGTTGTAAAATAGAATACTATTCAGAATAGTTGTCACCTTATTCTAGAAGTAGATACATATTATGTAAA
AGTTGAATTGTAGTGAAGGA

Product: two-component system sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1345; Mature: 1344

Protein sequence:

>1345_residues
MGKQSVFILFFFLNLLIHNAYAYNLKQVADKEYMSNSSITSLCQDERGLMWIGTCDGLNIYDGQEIEEFKTRDKEDYLSG
NLIDNIVYTGEDIYWIQTYYGLNRLNRKTNTITHYNEFQKLFFMNKDSHGNLFIIQDSNCIYYYHKKEGVFKKINITGIP
ISDIVNFFIDGNNRMWVVMKGYNRCYDIQQEAASGDITLLPQKTNLIYQTSLIYCFNDEQSLYYIDKEFNFYAFHIPTQK
NEFIANLGKEIQERGKISSIVHYHNSYFVGFLMDGILLLEKQKETDHYQIQSLPINSGVFCLKKDRFQDIVWIGTDGQGV
YLYSNPLYSIKSMVLSNYTEKIERPVRAIYLDDERTFWVGTKGNGILKIYDYEFDKNISDCRAEVLTTSNSALSSNAVYC
FAKSHRNLLWIGDEEGLTYYSYREKRIKSIPIRIGNEDFKYIHGIYETADSELWLASVGMGVVKARIAGTPDNPVIVDAQ
RYVINDGELGSNYFFTIYAENEANLLFGNKGYGVFRYNETTNGLEPVSTHKYENMTLNNILAISKDSSNNYLFGTSYGLI
KYTSETSYQLFNAKNGFLNNTIHAILRNSSDNFWLSTNLGLINFDTKRNVFRSYGFGDGLKVVEFSDGAAFRDSRTGTLF
FGGINGVVAIRADGRPEQLYMPPVYFDKLSIFGEQYNLGEFLTRKKETEVLNLQYDQNFFSVSFASVDYLNGNNCTYFYK
LKGLSDQWVNNGSESGVSFTNMAPGEYTLLVKYYNSVFDKESDVYSLVIRIGDPWYASWWAYLIYAFCLLLLAALLIRSF
ILRSKRKKQELLNEIEKRHQKNVFESKLRFFTNIAHEFCTPLTLIYSPCGRILSSKGLSKFVVDYVQMIQTNAERLNNLI
HELIEFRRIETGNREVRIESLNVSSIVKGIAKTFVEMAKSRNITFLSKIPEQVMWNSDKGFLNTIIINLISNAFKYTPDG
QSIKIEVDTSGENMLTLRVANEGSTIKEKDFQYIFNRYAILDNFENQDEKNFSRNGLGLAISYNMAKLLNGTLKVENTPD
GWVMFTLTLPVVELTTGVAETKRLTAEYIPKIDTQSILKLPQYEFDKMRPTLLVVDDEIEMLWFIGEIFSADFNVVTLQD
PERLDQVMNEVYPNVIICDVMMPGMGGIELTRRIKSVKETAHIPIIVVSGRHEMEQQMEALSAGAEMYITKPFSAEYLRI
SVCQVIERKEVLKNYFSSPISSFEKSDGKLTHKESKKFLQSVLKIINDNITNKDLTPRYIADRLAISPRSLYRKMEEIGE
DSPTDLIKECRLHIAKDLLLTTKKTIDEIVFDSGFSNKVTFFKVFREKYECTPKEFRQKHLAEVQ

Sequences:

>Translated_1345_residues
MGKQSVFILFFFLNLLIHNAYAYNLKQVADKEYMSNSSITSLCQDERGLMWIGTCDGLNIYDGQEIEEFKTRDKEDYLSG
NLIDNIVYTGEDIYWIQTYYGLNRLNRKTNTITHYNEFQKLFFMNKDSHGNLFIIQDSNCIYYYHKKEGVFKKINITGIP
ISDIVNFFIDGNNRMWVVMKGYNRCYDIQQEAASGDITLLPQKTNLIYQTSLIYCFNDEQSLYYIDKEFNFYAFHIPTQK
NEFIANLGKEIQERGKISSIVHYHNSYFVGFLMDGILLLEKQKETDHYQIQSLPINSGVFCLKKDRFQDIVWIGTDGQGV
YLYSNPLYSIKSMVLSNYTEKIERPVRAIYLDDERTFWVGTKGNGILKIYDYEFDKNISDCRAEVLTTSNSALSSNAVYC
FAKSHRNLLWIGDEEGLTYYSYREKRIKSIPIRIGNEDFKYIHGIYETADSELWLASVGMGVVKARIAGTPDNPVIVDAQ
RYVINDGELGSNYFFTIYAENEANLLFGNKGYGVFRYNETTNGLEPVSTHKYENMTLNNILAISKDSSNNYLFGTSYGLI
KYTSETSYQLFNAKNGFLNNTIHAILRNSSDNFWLSTNLGLINFDTKRNVFRSYGFGDGLKVVEFSDGAAFRDSRTGTLF
FGGINGVVAIRADGRPEQLYMPPVYFDKLSIFGEQYNLGEFLTRKKETEVLNLQYDQNFFSVSFASVDYLNGNNCTYFYK
LKGLSDQWVNNGSESGVSFTNMAPGEYTLLVKYYNSVFDKESDVYSLVIRIGDPWYASWWAYLIYAFCLLLLAALLIRSF
ILRSKRKKQELLNEIEKRHQKNVFESKLRFFTNIAHEFCTPLTLIYSPCGRILSSKGLSKFVVDYVQMIQTNAERLNNLI
HELIEFRRIETGNREVRIESLNVSSIVKGIAKTFVEMAKSRNITFLSKIPEQVMWNSDKGFLNTIIINLISNAFKYTPDG
QSIKIEVDTSGENMLTLRVANEGSTIKEKDFQYIFNRYAILDNFENQDEKNFSRNGLGLAISYNMAKLLNGTLKVENTPD
GWVMFTLTLPVVELTTGVAETKRLTAEYIPKIDTQSILKLPQYEFDKMRPTLLVVDDEIEMLWFIGEIFSADFNVVTLQD
PERLDQVMNEVYPNVIICDVMMPGMGGIELTRRIKSVKETAHIPIIVVSGRHEMEQQMEALSAGAEMYITKPFSAEYLRI
SVCQVIERKEVLKNYFSSPISSFEKSDGKLTHKESKKFLQSVLKIINDNITNKDLTPRYIADRLAISPRSLYRKMEEIGE
DSPTDLIKECRLHIAKDLLLTTKKTIDEIVFDSGFSNKVTFFKVFREKYECTPKEFRQKHLAEVQ
>Mature_1344_residues
GKQSVFILFFFLNLLIHNAYAYNLKQVADKEYMSNSSITSLCQDERGLMWIGTCDGLNIYDGQEIEEFKTRDKEDYLSGN
LIDNIVYTGEDIYWIQTYYGLNRLNRKTNTITHYNEFQKLFFMNKDSHGNLFIIQDSNCIYYYHKKEGVFKKINITGIPI
SDIVNFFIDGNNRMWVVMKGYNRCYDIQQEAASGDITLLPQKTNLIYQTSLIYCFNDEQSLYYIDKEFNFYAFHIPTQKN
EFIANLGKEIQERGKISSIVHYHNSYFVGFLMDGILLLEKQKETDHYQIQSLPINSGVFCLKKDRFQDIVWIGTDGQGVY
LYSNPLYSIKSMVLSNYTEKIERPVRAIYLDDERTFWVGTKGNGILKIYDYEFDKNISDCRAEVLTTSNSALSSNAVYCF
AKSHRNLLWIGDEEGLTYYSYREKRIKSIPIRIGNEDFKYIHGIYETADSELWLASVGMGVVKARIAGTPDNPVIVDAQR
YVINDGELGSNYFFTIYAENEANLLFGNKGYGVFRYNETTNGLEPVSTHKYENMTLNNILAISKDSSNNYLFGTSYGLIK
YTSETSYQLFNAKNGFLNNTIHAILRNSSDNFWLSTNLGLINFDTKRNVFRSYGFGDGLKVVEFSDGAAFRDSRTGTLFF
GGINGVVAIRADGRPEQLYMPPVYFDKLSIFGEQYNLGEFLTRKKETEVLNLQYDQNFFSVSFASVDYLNGNNCTYFYKL
KGLSDQWVNNGSESGVSFTNMAPGEYTLLVKYYNSVFDKESDVYSLVIRIGDPWYASWWAYLIYAFCLLLLAALLIRSFI
LRSKRKKQELLNEIEKRHQKNVFESKLRFFTNIAHEFCTPLTLIYSPCGRILSSKGLSKFVVDYVQMIQTNAERLNNLIH
ELIEFRRIETGNREVRIESLNVSSIVKGIAKTFVEMAKSRNITFLSKIPEQVMWNSDKGFLNTIIINLISNAFKYTPDGQ
SIKIEVDTSGENMLTLRVANEGSTIKEKDFQYIFNRYAILDNFENQDEKNFSRNGLGLAISYNMAKLLNGTLKVENTPDG
WVMFTLTLPVVELTTGVAETKRLTAEYIPKIDTQSILKLPQYEFDKMRPTLLVVDDEIEMLWFIGEIFSADFNVVTLQDP
ERLDQVMNEVYPNVIICDVMMPGMGGIELTRRIKSVKETAHIPIIVVSGRHEMEQQMEALSAGAEMYITKPFSAEYLRIS
VCQVIERKEVLKNYFSSPISSFEKSDGKLTHKESKKFLQSVLKIINDNITNKDLTPRYIADRLAISPRSLYRKMEEIGED
SPTDLIKECRLHIAKDLLLTTKKTIDEIVFDSGFSNKVTFFKVFREKYECTPKEFRQKHLAEVQ

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=24.5238095238095, Blast_Score=121, Evalue=4e-28,
Organism=Escherichia coli, GI48994928, Length=393, Percent_Identity=24.1730279898219, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=26.1904761904762, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=24.1803278688525, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=245, Percent_Identity=26.1224489795918, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1786599, Length=124, Percent_Identity=34.6774193548387, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=361, Percent_Identity=24.0997229916898, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=25.1063829787234, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=283, Percent_Identity=25.4416961130742, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=23.9130434782609, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 155103; Mature: 154971

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKQSVFILFFFLNLLIHNAYAYNLKQVADKEYMSNSSITSLCQDERGLMWIGTCDGLNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCC
YDGQEIEEFKTRDKEDYLSGNLIDNIVYTGEDIYWIQTYYGLNRLNRKTNTITHYNEFQK
CCCCHHHHHHCCCCHHHCCCCCHHCEEECCCEEEEEEEEHHHHHHCCCCCCEEHHHHHHH
LFFMNKDSHGNLFIIQDSNCIYYYHKKEGVFKKINITGIPISDIVNFFIDGNNRMWVVMK
EEEECCCCCCCEEEEECCCEEEEEEECCCCEEEEEEECCCHHHHHEEEECCCCEEEEEEC
GYNRCYDIQQEAASGDITLLPQKTNLIYQTSLIYCFNDEQSLYYIDKEFNFYAFHIPTQK
CCCHHHHHHHHCCCCCEEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCEEEEECCCCC
NEFIANLGKEIQERGKISSIVHYHNSYFVGFLMDGILLLEKQKETDHYQIQSLPINSGVF
HHHHHHHHHHHHHCCCHHHHHHHCCCEEHHHHHCCHHEEEECCCCCCEEEEEECCCCCEE
CLKKDRFQDIVWIGTDGQGVYLYSNPLYSIKSMVLSNYTEKIERPVRAIYLDDERTFWVG
EEECCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEE
TKGNGILKIYDYEFDKNISDCRAEVLTTSNSALSSNAVYCFAKSHRNLLWIGDEEGLTYY
ECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCEEE
SYREKRIKSIPIRIGNEDFKYIHGIYETADSELWLASVGMGVVKARIAGTPDNPVIVDAQ
HHHHHHHHCCCEEECCCHHHHHHHHHHCCCCCEEEEHHCCHHEEEEECCCCCCCEEEECC
RYVINDGELGSNYFFTIYAENEANLLFGNKGYGVFRYNETTNGLEPVSTHKYENMTLNNI
EEEEECCCCCCCEEEEEEECCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECEE
LAISKDSSNNYLFGTSYGLIKYTSETSYQLFNAKNGFLNNTIHAILRNSSDNFWLSTNLG
EEEEECCCCCEEEECCCCEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCE
LINFDTKRNVFRSYGFGDGLKVVEFSDGAAFRDSRTGTLFFGGINGVVAIRADGRPEQLY
EEEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEEEEEECCCCCEEE
MPPVYFDKLSIFGEQYNLGEFLTRKKETEVLNLQYDQNFFSVSFASVDYLNGNNCTYFYK
CCCHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCEEEEEEEEEEEECCCCEEEEEE
LKGLSDQWVNNGSESGVSFTNMAPGEYTLLVKYYNSVFDKESDVYSLVIRIGDPWYASWW
ECCCCHHHHCCCCCCCCEEEECCCCCEEEEEEHHHHHHCCCCCEEEEEEEECCCHHHHHH
AYLIYAFCLLLLAALLIRSFILRSKRKKQELLNEIEKRHQKNVFESKLRFFTNIAHEFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLTLIYSPCGRILSSKGLSKFVVDYVQMIQTNAERLNNLIHELIEFRRIETGNREVRIES
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LNVSSIVKGIAKTFVEMAKSRNITFLSKIPEQVMWNSDKGFLNTIIINLISNAFKYTPDG
CCHHHHHHHHHHHHHHHHHCCCEEEHHHCCHHHCCCCCCCHHHHHHHHHHHHHHEECCCC
QSIKIEVDTSGENMLTLRVANEGSTIKEKDFQYIFNRYAILDNFENQDEKNFSRNGLGLA
CEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
ISYNMAKLLNGTLKVENTPDGWVMFTLTLPVVELTTGVAETKRLTAEYIPKIDTQSILKL
EECCHHHHCCCEEEECCCCCCEEEEEEEECHHHHHCCHHHHHHHHHHHCCCCCCHHHHHC
PQYEFDKMRPTLLVVDDEIEMLWFIGEIFSADFNVVTLQDPERLDQVMNEVYPNVIICDV
CCCHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEE
MMPGMGGIELTRRIKSVKETAHIPIIVVSGRHEMEQQMEALSAGAEMYITKPFSAEYLRI
ECCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCHHHH
SVCQVIERKEVLKNYFSSPISSFEKSDGKLTHKESKKFLQSVLKIINDNITNKDLTPRYI
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
ADRLAISPRSLYRKMEEIGEDSPTDLIKECRLHIAKDLLLTTKKTIDEIVFDSGFSNKVT
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
FFKVFREKYECTPKEFRQKHLAEVQ
HHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GKQSVFILFFFLNLLIHNAYAYNLKQVADKEYMSNSSITSLCQDERGLMWIGTCDGLNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCC
YDGQEIEEFKTRDKEDYLSGNLIDNIVYTGEDIYWIQTYYGLNRLNRKTNTITHYNEFQK
CCCCHHHHHHCCCCHHHCCCCCHHCEEECCCEEEEEEEEHHHHHHCCCCCCEEHHHHHHH
LFFMNKDSHGNLFIIQDSNCIYYYHKKEGVFKKINITGIPISDIVNFFIDGNNRMWVVMK
EEEECCCCCCCEEEEECCCEEEEEEECCCCEEEEEEECCCHHHHHEEEECCCCEEEEEEC
GYNRCYDIQQEAASGDITLLPQKTNLIYQTSLIYCFNDEQSLYYIDKEFNFYAFHIPTQK
CCCHHHHHHHHCCCCCEEEEECCCCEEEEEEEEEEECCCCEEEEEECCCCEEEEECCCCC
NEFIANLGKEIQERGKISSIVHYHNSYFVGFLMDGILLLEKQKETDHYQIQSLPINSGVF
HHHHHHHHHHHHHCCCHHHHHHHCCCEEHHHHHCCHHEEEECCCCCCEEEEEECCCCCEE
CLKKDRFQDIVWIGTDGQGVYLYSNPLYSIKSMVLSNYTEKIERPVRAIYLDDERTFWVG
EEECCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEE
TKGNGILKIYDYEFDKNISDCRAEVLTTSNSALSSNAVYCFAKSHRNLLWIGDEEGLTYY
ECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCEEE
SYREKRIKSIPIRIGNEDFKYIHGIYETADSELWLASVGMGVVKARIAGTPDNPVIVDAQ
HHHHHHHHCCCEEECCCHHHHHHHHHHCCCCCEEEEHHCCHHEEEEECCCCCCCEEEECC
RYVINDGELGSNYFFTIYAENEANLLFGNKGYGVFRYNETTNGLEPVSTHKYENMTLNNI
EEEEECCCCCCCEEEEEEECCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECEE
LAISKDSSNNYLFGTSYGLIKYTSETSYQLFNAKNGFLNNTIHAILRNSSDNFWLSTNLG
EEEEECCCCCEEEECCCCEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCE
LINFDTKRNVFRSYGFGDGLKVVEFSDGAAFRDSRTGTLFFGGINGVVAIRADGRPEQLY
EEEECHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEEEEEECCCCCEEE
MPPVYFDKLSIFGEQYNLGEFLTRKKETEVLNLQYDQNFFSVSFASVDYLNGNNCTYFYK
CCCHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEEECCCEEEEEEEEEEEECCCCEEEEEE
LKGLSDQWVNNGSESGVSFTNMAPGEYTLLVKYYNSVFDKESDVYSLVIRIGDPWYASWW
ECCCCHHHHCCCCCCCCEEEECCCCCEEEEEEHHHHHHCCCCCEEEEEEEECCCHHHHHH
AYLIYAFCLLLLAALLIRSFILRSKRKKQELLNEIEKRHQKNVFESKLRFFTNIAHEFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLTLIYSPCGRILSSKGLSKFVVDYVQMIQTNAERLNNLIHELIEFRRIETGNREVRIES
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LNVSSIVKGIAKTFVEMAKSRNITFLSKIPEQVMWNSDKGFLNTIIINLISNAFKYTPDG
CCHHHHHHHHHHHHHHHHHCCCEEEHHHCCHHHCCCCCCCHHHHHHHHHHHHHHEECCCC
QSIKIEVDTSGENMLTLRVANEGSTIKEKDFQYIFNRYAILDNFENQDEKNFSRNGLGLA
CEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
ISYNMAKLLNGTLKVENTPDGWVMFTLTLPVVELTTGVAETKRLTAEYIPKIDTQSILKL
EECCHHHHCCCEEEECCCCCCEEEEEEEECHHHHHCCHHHHHHHHHHHCCCCCCHHHHHC
PQYEFDKMRPTLLVVDDEIEMLWFIGEIFSADFNVVTLQDPERLDQVMNEVYPNVIICDV
CCCHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEEEE
MMPGMGGIELTRRIKSVKETAHIPIIVVSGRHEMEQQMEALSAGAEMYITKPFSAEYLRI
ECCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCHHHH
SVCQVIERKEVLKNYFSSPISSFEKSDGKLTHKESKKFLQSVLKIINDNITNKDLTPRYI
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
ADRLAISPRSLYRKMEEIGEDSPTDLIKECRLHIAKDLLLTTKKTIDEIVFDSGFSNKVT
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
FFKVFREKYECTPKEFRQKHLAEVQ
HHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]