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The map label for this gene is thrS [H]

Identifier: 29347937

GI number: 29347937

Start: 3156436

End: 3158109

Strand: Reverse

Name: thrS [H]

Synonym: BT_2527

Alternate gene names: 29347937

Gene position: 3158109-3156436 (Counterclockwise)

Preceding gene: 29347947

Following gene: 29347936

Centisome position: 50.45

GC content: 45.34

Gene sequence:

>1674_bases
ATGAAACAGATGTTACAAATATGTTGCAAAAATAATAATATTTATAAAGAATTCCCTATCGGAAGCTCACTTTTGGATAT
TTATTACGGTTTTAATCTTAATTTTCCTTATCAGGTAGTCAGTGCCAAGGTGAATAACCGTTCCGAAGGTCTCAATTTCA
AAGTATATAATAACAAGGATATAGAGTTTCTGGATGTGCGCGATTCATCCGGTATGCGTACGTATGTGCGGTCACTCTGC
TTTGTCTTGTTCAAGGCTGTCAGTGAACTTTTTCCCGAAGGGAAGCTGTTTGTGGAACACCCGGTATCCAAAGGTTATTT
CTGTAATCTGCGGATCGGCCGCCCCATTACATTGGAAGATGTGACGCGTATCAAACAGCGTATGCAGGAGATTATCGCAG
AAAATATCTCTTATCACCGCATCGAATGCCATACGGCTGAGGCCGTGCGTGTGTTCAGCGAACGCGGGATGAATGATAAG
GTGAGGCTGCTCGAAACTTCCGGTTCGCTATATACCTATTATTATACGCTGGGCGATACGGTCGATTATTATTATGGCAA
TCTGCTCCCCAGTACCGGATATATCAAGTTGTTCGACATCGTGAAATACTATGATGGCCTGCTGCTGCGCATTCCCAATA
AAGAGAATCCGGATGTGCTGGAGGAAGTGGTGAAGCAGGAGAAGATGCTGGATGTATTTAAGGAGTATCTCAACTGGAGT
TATATCATGGGACTTAATAACGCCGGCGACTTTAACCTCGCCTGCGAAGAAGGGCACGCTACGGATTTAATCAATGTAGC
GGAAGCGTTGCAGGAAAAGAAAATAGCCCAGATTGCCGATACGATCTTCCATCGTGGGGAAAACGGTGACCGGGTGAAAC
TGATTTTGATTTCCGGTCCGTCCTCTTCGGGTAAGACCACTTTCAGCAAACGTCTTTCCATCCAGTTGATGACGAACGGG
CTCAAACCCTTCCCGATCTCCTTGGACAATTATTTCGTAGACCGTGAAGAGACACCTCTGGATGAAAACGGTAACTATGA
TTATGAGTCTCTGTATGCGCTCGATCTGGAATTGTTTAACCAGCAGTTGCAGGCTTTGCTGCGCGGTGAGGAAGTGGAGC
TTCCGCGCTTTAACTTCTCTCTGGGGAAGAAGGAATATAAAGGTGATAAACTGAAAATTGAAGATAATACGATTCTCATT
CTGGAAGGTATTCATGCGTTGAATCCGGAACTGACACCGCATATCCCGGATGAAAAGAAGTTCAAGATTTATGTCTCGGC
ATTGACCACTATTTCTTTGGACGATCATAACTGGATTCCTACGACAGACAATCGTTTGCTTCGCCGCATTATCCGCGACT
TTAATTACCGGGGATATTCGGCCCGCGAGACTATCTCCCGCTGGCCTAGTGTGCGTGCCGGCGAAGATAAATGGATATTC
CCTTATCAGGAGAATGCGGATGTGATGTTCAACTCGGCGCTGTTGTTTGAATTTGCAGTCCTTCGCCTGCACGCGGAACC
TATTTTGATGGGCGTTCCGCGCAATTGTCCGGAATATTGTGAGGCGTACCGGTTGCTGAAATTTATTAAATATTTCGTTC
CGGTGCAGGATAAGGAAATTCCCCCGACGTCTTTACTCAGGGAGTTTTTGGGAGGAAGTAGCTTCAAATATTAG

Upstream 100 bases:

>100_bases
AAGAATATTCCATCTATAATAATTTTAGTGGTTGTTTGTTCTCTATCTGATTACTAAGTATATTTAGTCCCATGTTATTC
ACCTTATTAAAAAGACTACG

Downstream 100 bases:

>100_bases
ATAATAAATTTATTTAAGAGAATTATTTTGGAATTTATAGTTATTGTATAAATATAAGTTCGTAACTTCGCGCCGCAAAA
AACAAGCGTGGCAATATGTT

Product: uridine kinase

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MKQMLQICCKNNNIYKEFPIGSSLLDIYYGFNLNFPYQVVSAKVNNRSEGLNFKVYNNKDIEFLDVRDSSGMRTYVRSLC
FVLFKAVSELFPEGKLFVEHPVSKGYFCNLRIGRPITLEDVTRIKQRMQEIIAENISYHRIECHTAEAVRVFSERGMNDK
VRLLETSGSLYTYYYTLGDTVDYYYGNLLPSTGYIKLFDIVKYYDGLLLRIPNKENPDVLEEVVKQEKMLDVFKEYLNWS
YIMGLNNAGDFNLACEEGHATDLINVAEALQEKKIAQIADTIFHRGENGDRVKLILISGPSSSGKTTFSKRLSIQLMTNG
LKPFPISLDNYFVDREETPLDENGNYDYESLYALDLELFNQQLQALLRGEEVELPRFNFSLGKKEYKGDKLKIEDNTILI
LEGIHALNPELTPHIPDEKKFKIYVSALTTISLDDHNWIPTTDNRLLRRIIRDFNYRGYSARETISRWPSVRAGEDKWIF
PYQENADVMFNSALLFEFAVLRLHAEPILMGVPRNCPEYCEAYRLLKFIKYFVPVQDKEIPPTSLLREFLGGSSFKY

Sequences:

>Translated_557_residues
MKQMLQICCKNNNIYKEFPIGSSLLDIYYGFNLNFPYQVVSAKVNNRSEGLNFKVYNNKDIEFLDVRDSSGMRTYVRSLC
FVLFKAVSELFPEGKLFVEHPVSKGYFCNLRIGRPITLEDVTRIKQRMQEIIAENISYHRIECHTAEAVRVFSERGMNDK
VRLLETSGSLYTYYYTLGDTVDYYYGNLLPSTGYIKLFDIVKYYDGLLLRIPNKENPDVLEEVVKQEKMLDVFKEYLNWS
YIMGLNNAGDFNLACEEGHATDLINVAEALQEKKIAQIADTIFHRGENGDRVKLILISGPSSSGKTTFSKRLSIQLMTNG
LKPFPISLDNYFVDREETPLDENGNYDYESLYALDLELFNQQLQALLRGEEVELPRFNFSLGKKEYKGDKLKIEDNTILI
LEGIHALNPELTPHIPDEKKFKIYVSALTTISLDDHNWIPTTDNRLLRRIIRDFNYRGYSARETISRWPSVRAGEDKWIF
PYQENADVMFNSALLFEFAVLRLHAEPILMGVPRNCPEYCEAYRLLKFIKYFVPVQDKEIPPTSLLREFLGGSSFKY
>Mature_557_residues
MKQMLQICCKNNNIYKEFPIGSSLLDIYYGFNLNFPYQVVSAKVNNRSEGLNFKVYNNKDIEFLDVRDSSGMRTYVRSLC
FVLFKAVSELFPEGKLFVEHPVSKGYFCNLRIGRPITLEDVTRIKQRMQEIIAENISYHRIECHTAEAVRVFSERGMNDK
VRLLETSGSLYTYYYTLGDTVDYYYGNLLPSTGYIKLFDIVKYYDGLLLRIPNKENPDVLEEVVKQEKMLDVFKEYLNWS
YIMGLNNAGDFNLACEEGHATDLINVAEALQEKKIAQIADTIFHRGENGDRVKLILISGPSSSGKTTFSKRLSIQLMTNG
LKPFPISLDNYFVDREETPLDENGNYDYESLYALDLELFNQQLQALLRGEEVELPRFNFSLGKKEYKGDKLKIEDNTILI
LEGIHALNPELTPHIPDEKKFKIYVSALTTISLDDHNWIPTTDNRLLRRIIRDFNYRGYSARETISRWPSVRAGEDKWIF
PYQENADVMFNSALLFEFAVLRLHAEPILMGVPRNCPEYCEAYRLLKFIKYFVPVQDKEIPPTSLLREFLGGSSFKY

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 64577; Mature: 64577

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQMLQICCKNNNIYKEFPIGSSLLDIYYGFNLNFPYQVVSAKVNNRSEGLNFKVYNNKD
CHHHHHHHHCCCCEEEECCCCCHHHHHEECCCCCCCHHEEEEEECCCCCCCEEEEECCCC
IEFLDVRDSSGMRTYVRSLCFVLFKAVSELFPEGKLFVEHPVSKGYFCNLRIGRPITLED
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCHHH
VTRIKQRMQEIIAENISYHRIECHTAEAVRVFSERGMNDKVRLLETSGSLYTYYYTLGDT
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECCC
VDYYYGNLLPSTGYIKLFDIVKYYDGLLLRIPNKENPDVLEEVVKQEKMLDVFKEYLNWS
HHHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
YIMGLNNAGDFNLACEEGHATDLINVAEALQEKKIAQIADTIFHRGENGDRVKLILISGP
EEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
SSSGKTTFSKRLSIQLMTNGLKPFPISLDNYFVDREETPLDENGNYDYESLYALDLELFN
CCCCCCCHHHHEEEEEEECCCCCCEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
QQLQALLRGEEVELPRFNFSLGKKEYKGDKLKIEDNTILILEGIHALNPELTPHIPDEKK
HHHHHHHCCCCCCCCCCCCCCCCHHCCCCEEEEECCEEEEEECCHHCCCCCCCCCCCCCC
FKIYVSALTTISLDDHNWIPTTDNRLLRRIIRDFNYRGYSARETISRWPSVRAGEDKWIF
EEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCEEE
PYQENADVMFNSALLFEFAVLRLHAEPILMGVPRNCPEYCEAYRLLKFIKYFVPVQDKEI
CCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PPTSLLREFLGGSSFKY
CHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQMLQICCKNNNIYKEFPIGSSLLDIYYGFNLNFPYQVVSAKVNNRSEGLNFKVYNNKD
CHHHHHHHHCCCCEEEECCCCCHHHHHEECCCCCCCHHEEEEEECCCCCCCEEEEECCCC
IEFLDVRDSSGMRTYVRSLCFVLFKAVSELFPEGKLFVEHPVSKGYFCNLRIGRPITLED
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCHHH
VTRIKQRMQEIIAENISYHRIECHTAEAVRVFSERGMNDKVRLLETSGSLYTYYYTLGDT
HHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEEECCC
VDYYYGNLLPSTGYIKLFDIVKYYDGLLLRIPNKENPDVLEEVVKQEKMLDVFKEYLNWS
HHHHHCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
YIMGLNNAGDFNLACEEGHATDLINVAEALQEKKIAQIADTIFHRGENGDRVKLILISGP
EEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
SSSGKTTFSKRLSIQLMTNGLKPFPISLDNYFVDREETPLDENGNYDYESLYALDLELFN
CCCCCCCHHHHEEEEEEECCCCCCEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
QQLQALLRGEEVELPRFNFSLGKKEYKGDKLKIEDNTILILEGIHALNPELTPHIPDEKK
HHHHHHHCCCCCCCCCCCCCCCCHHCCCCEEEEECCEEEEEECCHHCCCCCCCCCCCCCC
FKIYVSALTTISLDDHNWIPTTDNRLLRRIIRDFNYRGYSARETISRWPSVRAGEDKWIF
EEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCEEE
PYQENADVMFNSALLFEFAVLRLHAEPILMGVPRNCPEYCEAYRLLKFIKYFVPVQDKEI
CCCCCCCEEEHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PPTSLLREFLGGSSFKY
CHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA