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The map label for this gene is phoP [H]

Identifier: 29346338

GI number: 29346338

Start: 1142021

End: 1142698

Strand: Reverse

Name: phoP [H]

Synonym: BT_0928

Alternate gene names: 29346338

Gene position: 1142698-1142021 (Counterclockwise)

Preceding gene: 29346339

Following gene: 29346337

Centisome position: 18.25

GC content: 39.97

Gene sequence:

>678_bases
ATGAAGATATTAATTGTAGAAGATGAACCCTCTTTAAGAGAATTGATCCAACGTTCGCTGGAAAAAGAACGTTATGTCGT
AGAAACGGCCGGAGACTTCAACAGTGCATTATACAAAATAGAAGATTACGACTATGATTGTGTCTTACTGGATATTATGC
TGCCGGACGGGAGCGGTCTTGACCTTCTCGAACGTTTGAAAGCTCTCCACAAACGGGAAAATGTGATTATTATCTCTGCC
AAAGATTCGCTGGAAGACAAAGTACTGGGACTGGAATTAGGAGCTGACGATTATTTGCCGAAACCATTTCATCTGGCAGA
ATTAAATGCACGGATCAAAAGTGTGATCCGTCGGAATCAACATGATGGAGAAATCTATATCCGTCAGGGAAATGTAAAGA
TAGAACCCGATAAATACCGGGTGTTTGTCAACGAACAGGAGCTGGAACTGAACAGAAAAGAATATGATATCCTGCTTTAT
TTCATAAATCGTCCCGGCCGTCTGGTCAATAAAAACACACTGGCAGAATCGGTATGGGGAGACCACATCGATCAAGTGGA
TAACTTTGACTTCATTTATGCACAAATCAAAAATCTTCGCAAAAAATTGAAGGATGCAAAAGCAAATATTGAAATCAAGG
CCGTTTATGGATTCGGCTATAAACTGATTGTAGAATAA

Upstream 100 bases:

>100_bases
TTTTAAAATTGAGAATCTGACTCTTTTTTTATCCATTTCAGTTTTATTTCAGAAATATCTCTTTTCTTTGTAGACAGTAA
TAAAGAAAGGAGAAGATTTT

Downstream 100 bases:

>100_bases
TCGAAACCAGAAAGGATCATCCATGAAACTTATATATTATATCATTTTTCGCATCACCCTCGCCCTGACTCTTATCCTGA
CTGTCTGGGCAGTCTTTTTC

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKILIVEDEPSLRELIQRSLEKERYVVETAGDFNSALYKIEDYDYDCVLLDIMLPDGSGLDLLERLKALHKRENVIIISA
KDSLEDKVLGLELGADDYLPKPFHLAELNARIKSVIRRNQHDGEIYIRQGNVKIEPDKYRVFVNEQELELNRKEYDILLY
FINRPGRLVNKNTLAESVWGDHIDQVDNFDFIYAQIKNLRKKLKDAKANIEIKAVYGFGYKLIVE

Sequences:

>Translated_225_residues
MKILIVEDEPSLRELIQRSLEKERYVVETAGDFNSALYKIEDYDYDCVLLDIMLPDGSGLDLLERLKALHKRENVIIISA
KDSLEDKVLGLELGADDYLPKPFHLAELNARIKSVIRRNQHDGEIYIRQGNVKIEPDKYRVFVNEQELELNRKEYDILLY
FINRPGRLVNKNTLAESVWGDHIDQVDNFDFIYAQIKNLRKKLKDAKANIEIKAVYGFGYKLIVE
>Mature_225_residues
MKILIVEDEPSLRELIQRSLEKERYVVETAGDFNSALYKIEDYDYDCVLLDIMLPDGSGLDLLERLKALHKRENVIIISA
KDSLEDKVLGLELGADDYLPKPFHLAELNARIKSVIRRNQHDGEIYIRQGNVKIEPDKYRVFVNEQELELNRKEYDILLY
FINRPGRLVNKNTLAESVWGDHIDQVDNFDFIYAQIKNLRKKLKDAKANIEIKAVYGFGYKLIVE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=34.8214285714286, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.2678571428571, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=31.390134529148, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=33.1838565022422, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=31.5315315315315, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=32.2869955156951, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=34.6320346320346, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=29.5652173913043, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=31.390134529148, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.9592760180996, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=28.4444444444444, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.4721030042918, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=28.9099526066351, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=31.4516129032258, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=32.2033898305085, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=29.0598290598291, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26229; Mature: 26229

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVEDEPSLRELIQRSLEKERYVVETAGDFNSALYKIEDYDYDCVLLDIMLPDGSGL
CEEEEECCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEECCCCCEEEEEEEECCCCCH
DLLERLKALHKRENVIIISAKDSLEDKVLGLELGADDYLPKPFHLAELNARIKSVIRRNQ
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCC
HDGEIYIRQGNVKIEPDKYRVFVNEQELELNRKEYDILLYFINRPGRLVNKNTLAESVWG
CCCEEEEEECCEEECCCCEEEEEECHHHCCCCCCEEEEEEEECCCCCEECCHHHHHHHHH
DHIDQVDNFDFIYAQIKNLRKKLKDAKANIEIKAVYGFGYKLIVE
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCEEEEEC
>Mature Secondary Structure
MKILIVEDEPSLRELIQRSLEKERYVVETAGDFNSALYKIEDYDYDCVLLDIMLPDGSGL
CEEEEECCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEECCCCCEEEEEEEECCCCCH
DLLERLKALHKRENVIIISAKDSLEDKVLGLELGADDYLPKPFHLAELNARIKSVIRRNQ
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCC
HDGEIYIRQGNVKIEPDKYRVFVNEQELELNRKEYDILLYFINRPGRLVNKNTLAESVWG
CCCEEEEEECCEEECCCCEEEEEECHHHCCCCCCEEEEEEEECCCCCEECCHHHHHHHHH
DHIDQVDNFDFIYAQIKNLRKKLKDAKANIEIKAVYGFGYKLIVE
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]