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The map label for this gene is fabD [H]

Identifier: 29346199

GI number: 29346199

Start: 978557

End: 979444

Strand: Reverse

Name: fabD [H]

Synonym: BT_0789

Alternate gene names: 29346199

Gene position: 979444-978557 (Counterclockwise)

Preceding gene: 29346200

Following gene: 29346198

Centisome position: 15.65

GC content: 46.06

Gene sequence:

>888_bases
ATGAAAGCATTTGTATTTCCCGGTCAAGGTGCTCAGTTCGTAGGAATGGGTAAAGACCTGTATGAAAACTCAGCTTTAGC
AAAAGAATTGTTTGAAAAAGCAAATGATATCCTCGGATATCGCATTACAGATATCATGTTCAATGGTACAGACGAAGACC
TTCGTCAGACAAAGGTTACTCAACCTGCCGTATTCCTTCACTCTGTTATCTCTGCTCTTTGTATGGGCGATGATTTCAAA
CCGGAAATGACAGCCGGACACTCACTCGGTGAGTTCTCTGCATTGGTGGCTGCCGGTGCCCTGAGCTTTGAAGACGGATT
GAAACTGGTTTATGCTCGTGCAATGGCTATGCAAAAAGCTTGCGAAGCAACTCCTTCTACGATGGCCGCTATCATTGCAT
TGCCGGATGAAAAGGTAGAAGAAATCTGTGCATCTGTTAATGCAGAAGGTGAAGTTTGCGTACCTGCCAACTATAACTGC
CCGGGACAAATCGTAATCTCCGGTTCTGTACCAGGCATCGAAAAAGCCTGCGAACTGATGAAAGCTGCCGGTGCAAAACG
TGCTCTCCCATTAAAAGTAGGTGGTGCTTTCCACTCTCCGTTGATGGACCCGGCTAAAGTTGAGCTGGAAGCTGCTATCA
ACGCAACAGAAATCCATACTCCCAAATGTCCGGTATATCAGAATGTGGATGCACTTCCTCATACTGATCCCGCAGAAATC
AAAAAGAATCTGGTTGCCCAGCTGACTGCTTCCGTACGTTGGACTCAGTCTGTTAAGAATATGGTTGCCGATGGTGCTAC
TGATTTTACAGAATGCGGACCGGGTGCAGTATTGCAGGGATTGATCAAGAAAATAGATGGTACAGTAAGCGCTCACGGCA
TTGCATAA

Upstream 100 bases:

>100_bases
TTCCCGACTCCATTGCACAAATGTGTACATTTTGTGCGGTCGTATCATAAAAATCTGTAACTTTGCACCCGCATTTAAAA
ATCAATTAAATAATAAAGAT

Downstream 100 bases:

>100_bases
GCATTCGTAGATATACTTTACCTTTTCTCAACTATAGAGCGTGTCGACTAGTTTGCCGATACGCTTTTTTTATGCTTATT
AGTCAAACATGAGACAATTA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFNGTDEDLRQTKVTQPAVFLHSVISALCMGDDFK
PEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKACEATPSTMAAIIALPDEKVEEICASVNAEGEVCVPANYNC
PGQIVISGSVPGIEKACELMKAAGAKRALPLKVGGAFHSPLMDPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
KKNLVAQLTASVRWTQSVKNMVADGATDFTECGPGAVLQGLIKKIDGTVSAHGIA

Sequences:

>Translated_295_residues
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFNGTDEDLRQTKVTQPAVFLHSVISALCMGDDFK
PEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKACEATPSTMAAIIALPDEKVEEICASVNAEGEVCVPANYNC
PGQIVISGSVPGIEKACELMKAAGAKRALPLKVGGAFHSPLMDPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
KKNLVAQLTASVRWTQSVKNMVADGATDFTECGPGAVLQGLIKKIDGTVSAHGIA
>Mature_295_residues
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFNGTDEDLRQTKVTQPAVFLHSVISALCMGDDFK
PEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKACEATPSTMAAIIALPDEKVEEICASVNAEGEVCVPANYNC
PGQIVISGSVPGIEKACELMKAAGAKRALPLKVGGAFHSPLMDPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
KKNLVAQLTASVRWTQSVKNMVADGATDFTECGPGAVLQGLIKKIDGTVSAHGIA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=304, Percent_Identity=36.1842105263158, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=39.4495412844037, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1787334, Length=294, Percent_Identity=42.8571428571429, Blast_Score=192, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=31.9587628865979, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=291, Percent_Identity=27.8350515463918, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.5481727574751, Blast_Score=161, Evalue=4e-40,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31143; Mature: 31143

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFNGTDEDLRQTKVT
CCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHCC
QPAVFLHSVISALCMGDDFKPEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKA
CHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CEATPSTMAAIIALPDEKVEEICASVNAEGEVCVPANYNCPGQIVISGSVPGIEKACELM
HCCCHHHHEEEEECCHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCHHHHHHHH
KAAGAKRALPLKVGGAFHSPLMDPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
HHCCCCCCCEEEECCCHHCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCHHHH
KKNLVAQLTASVRWTQSVKNMVADGATDFTECGPGAVLQGLIKKIDGTVSAHGIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKAFVFPGQGAQFVGMGKDLYENSALAKELFEKANDILGYRITDIMFNGTDEDLRQTKVT
CCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHCC
QPAVFLHSVISALCMGDDFKPEMTAGHSLGEFSALVAAGALSFEDGLKLVYARAMAMQKA
CHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CEATPSTMAAIIALPDEKVEEICASVNAEGEVCVPANYNCPGQIVISGSVPGIEKACELM
HCCCHHHHEEEEECCHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCHHHHHHHH
KAAGAKRALPLKVGGAFHSPLMDPAKVELEAAINATEIHTPKCPVYQNVDALPHTDPAEI
HHCCCCCCCEEEECCCHHCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCHHHH
KKNLVAQLTASVRWTQSVKNMVADGATDFTECGPGAVLQGLIKKIDGTVSAHGIA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]