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The map label for this gene is sucC

Identifier: 29346198

GI number: 29346198

Start: 977227

End: 978357

Strand: Reverse

Name: sucC

Synonym: BT_0788

Alternate gene names: 29346198

Gene position: 978357-977227 (Counterclockwise)

Preceding gene: 29346199

Following gene: 29346197

Centisome position: 15.63

GC content: 45.09

Gene sequence:

>1131_bases
ATGAAAATACATGAATATCAAGCAAAAGAAATTTTCTCCAAGTATGGGATCCCTGTTGAAAGGCATACCCTATGTCGAAC
GGCTGCCGGCGCAGTTGCCGCATACAAGAGAATGGGCTCGGACAGAGTGGTTATTAAAGCACAAGTGCTGACCGGCGGAC
GGGGAAAAGCCGGAGGTGTTAAACTGGTAGATAATACAGAAGATACCTATCAGGAAGCTAAAAACATTCTGGGTATGAGT
ATTAAAGGGCTTCCTGTCAATCAGATACTGGTCAGCGAGGCGGTTGATATTGCCGCAGAATACTATGTCAGCTTCACCAT
TGACAGAAACACACGCTCGGTCATCCTTATGATGAGTGCGTCCGGTGGTATGGATATCGAAGAAGTAGCCCGGCAATCAC
CGGAAAAAATCATTCGCTATGCTATTGACCCATTCATCGGTCTGCCTGATTATCTGGCACGCCGTTTCGCATTCTCGCTC
TTCCCTCACATAGAACAAGCCGGCAGAATGGCCGCTATTCTGCAAGCACTCTACAAAATTTTCATGGAGAATGACGCATC
GCTGGTTGAAGTAAATCCATTGGCTCTTACCGCCAAAGGCATATTGATGGCTATTGACGCCAAAATTGTTTTTGACGATA
ATGCTCTTTACCGCCATCCGGATGTACTGAGTTTGTTTGATCCTACAGAAGAAGAAAAAGTAGAAGCGGATGCTAAAAAC
AAAGGATTCAGCTACGTTCACATGGATGGAAATATAGGCTGTATGGTAAATGGCGCCGGACTTGCTATGGCAACAATGGA
TATGATAAAACTTCATGGGGGAAATCCTGCCAACTTCCTTGATATTGGCGGTAGTTCGAACCCTGTCAAGGTGGTTGAAG
CTATGAAACTTCTCTTACAGGACGAGAAAGTAAAGGTCGTCCTGATAAACATTTTCGGAGGAATCACCCGTTGTGACGAT
GTAGCCATCGGTCTTATTCAGGCATTCGATCAGATTAAGAGTGATATACCTGTCATTGTCCGGCTCACAGGAACCAATGA
GCATCTCGGACGTGATCTTTTACGCAACCATAGCCGTTTTCAGATAGCTACAACTATGCAGGAAGCCGCTTTAATGGCTA
TCAAATCTTAA

Upstream 100 bases:

>100_bases
AATATGCTGTAAAACACACCATTAGTCTTCTCTACGAGCAAACATTCCGAATCTTTCACTTGTTTTCATTATAGGAATCA
TTTATTCAAATTCGCGGACC

Downstream 100 bases:

>100_bases
GATGAAATCACATAAAAAATGAAGGAACAATGAGTATATTAATAGATAAATCCACCCGTTTGATTGTACAAGGTATTACC
GGTAGAGACGGGCTTTTTCA

Product: succinyl-CoA synthetase beta chain

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKIHEYQAKEIFSKYGIPVERHTLCRTAAGAVAAYKRMGSDRVVIKAQVLTGGRGKAGGVKLVDNTEDTYQEAKNILGMS
IKGLPVNQILVSEAVDIAAEYYVSFTIDRNTRSVILMMSASGGMDIEEVARQSPEKIIRYAIDPFIGLPDYLARRFAFSL
FPHIEQAGRMAAILQALYKIFMENDASLVEVNPLALTAKGILMAIDAKIVFDDNALYRHPDVLSLFDPTEEEKVEADAKN
KGFSYVHMDGNIGCMVNGAGLAMATMDMIKLHGGNPANFLDIGGSSNPVKVVEAMKLLLQDEKVKVVLINIFGGITRCDD
VAIGLIQAFDQIKSDIPVIVRLTGTNEHLGRDLLRNHSRFQIATTMQEAALMAIKS

Sequences:

>Translated_376_residues
MKIHEYQAKEIFSKYGIPVERHTLCRTAAGAVAAYKRMGSDRVVIKAQVLTGGRGKAGGVKLVDNTEDTYQEAKNILGMS
IKGLPVNQILVSEAVDIAAEYYVSFTIDRNTRSVILMMSASGGMDIEEVARQSPEKIIRYAIDPFIGLPDYLARRFAFSL
FPHIEQAGRMAAILQALYKIFMENDASLVEVNPLALTAKGILMAIDAKIVFDDNALYRHPDVLSLFDPTEEEKVEADAKN
KGFSYVHMDGNIGCMVNGAGLAMATMDMIKLHGGNPANFLDIGGSSNPVKVVEAMKLLLQDEKVKVVLINIFGGITRCDD
VAIGLIQAFDQIKSDIPVIVRLTGTNEHLGRDLLRNHSRFQIATTMQEAALMAIKS
>Mature_376_residues
MKIHEYQAKEIFSKYGIPVERHTLCRTAAGAVAAYKRMGSDRVVIKAQVLTGGRGKAGGVKLVDNTEDTYQEAKNILGMS
IKGLPVNQILVSEAVDIAAEYYVSFTIDRNTRSVILMMSASGGMDIEEVARQSPEKIIRYAIDPFIGLPDYLARRFAFSL
FPHIEQAGRMAAILQALYKIFMENDASLVEVNPLALTAKGILMAIDAKIVFDDNALYRHPDVLSLFDPTEEEKVEADAKN
KGFSYVHMDGNIGCMVNGAGLAMATMDMIKLHGGNPANFLDIGGSSNPVKVVEAMKLLLQDEKVKVVLINIFGGITRCDD
VAIGLIQAFDQIKSDIPVIVRLTGTNEHLGRDLLRNHSRFQIATTMQEAALMAIKS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=374, Percent_Identity=41.4438502673797, Blast_Score=284, Evalue=8e-77,
Organism=Homo sapiens, GI11321583, Length=394, Percent_Identity=39.8477157360406, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=41.9889502762431, Blast_Score=280, Evalue=2e-75,
Organism=Escherichia coli, GI1786948, Length=357, Percent_Identity=47.0588235294118, Blast_Score=327, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=38.560411311054, Blast_Score=273, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=36.6412213740458, Blast_Score=268, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6321683, Length=373, Percent_Identity=39.6782841823056, Blast_Score=276, Evalue=3e-75,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=38.1074168797954, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI281361397, Length=372, Percent_Identity=36.8279569892473, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI281361395, Length=372, Percent_Identity=36.8279569892473, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI161078106, Length=371, Percent_Identity=36.6576819407008, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24645208, Length=371, Percent_Identity=36.6576819407008, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_BACTN (Q8A9M7)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809701.1
- HSSP:   P0A836
- ProteinModelPortal:   Q8A9M7
- SMR:   Q8A9M7
- GeneID:   1072236
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0788
- NMPDR:   fig|226186.1.peg.788
- HOGENOM:   HBG315432
- OMA:   LPIVVRM
- PhylomeDB:   Q8A9M7
- ProtClustDB:   CLSK259787
- BioCyc:   BTHE226186:BT_0788-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41197; Mature: 41197

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKEIFSKYGIPVERHTLCRTAAGAVAAYKRMGSDRVVIKAQVLTGGRGKAGGV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCE
KLVDNTEDTYQEAKNILGMSIKGLPVNQILVSEAVDIAAEYYVSFTIDRNTRSVILMMSA
EEECCCHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEEEEC
SGGMDIEEVARQSPEKIIRYAIDPFIGLPDYLARRFAFSLFPHIEQAGRMAAILQALYKI
CCCCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMENDASLVEVNPLALTAKGILMAIDAKIVFDDNALYRHPDVLSLFDPTEEEKVEADAKN
HHCCCCCEEEECCEEEEECCEEEEEEEEEEECCCCEEECCCEEEECCCCHHHHHHCCCCC
KGFSYVHMDGNIGCMVNGAGLAMATMDMIKLHGGNPANFLDIGGSSNPVKVVEAMKLLLQ
CCEEEEEECCCEEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCCHHHHHHHHHHHHC
DEKVKVVLINIFGGITRCDDVAIGLIQAFDQIKSDIPVIVRLTGTNEHLGRDLLRNHSRF
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCE
QIATTMQEAALMAIKS
EEEHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQAKEIFSKYGIPVERHTLCRTAAGAVAAYKRMGSDRVVIKAQVLTGGRGKAGGV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCE
KLVDNTEDTYQEAKNILGMSIKGLPVNQILVSEAVDIAAEYYVSFTIDRNTRSVILMMSA
EEECCCHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEEEEC
SGGMDIEEVARQSPEKIIRYAIDPFIGLPDYLARRFAFSLFPHIEQAGRMAAILQALYKI
CCCCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMENDASLVEVNPLALTAKGILMAIDAKIVFDDNALYRHPDVLSLFDPTEEEKVEADAKN
HHCCCCCEEEECCEEEEECCEEEEEEEEEEECCCCEEECCCEEEECCCCHHHHHHCCCCC
KGFSYVHMDGNIGCMVNGAGLAMATMDMIKLHGGNPANFLDIGGSSNPVKVVEAMKLLLQ
CCEEEEEECCCEEEEEECCCHHHHHHHHHEECCCCCCCEEECCCCCCHHHHHHHHHHHHC
DEKVKVVLINIFGGITRCDDVAIGLIQAFDQIKSDIPVIVRLTGTNEHLGRDLLRNHSRF
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCE
QIATTMQEAALMAIKS
EEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928