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The map label for this gene is murQ

Identifier: 29345543

GI number: 29345543

Start: 129836

End: 130669

Strand: Reverse

Name: murQ

Synonym: BT_0133

Alternate gene names: 29345543

Gene position: 130669-129836 (Counterclockwise)

Preceding gene: 29345544

Following gene: 29345540

Centisome position: 2.09

GC content: 46.64

Gene sequence:

>834_bases
ATGGAATTTATCAAGATAACAGAGCAACCATCGCTCTATGATGACCTCGACAAGAAGTCGGTAAAAGAGATTCTGGAAGA
TATCAATACTGAAGACCATAAAGTAGCGGATGCCGTGCAGAAAGCAATCCCACAAATAGAGAAACTGGTCACATTAATTA
TTCCCCGAGTAAAAAAAGGTGGGAGAATATTCTATATGGGGGCCGGAACAAGCGGACGTTTAGGTGTACTCGACGCTTCC
GAAATACCTCCGACTTTCGGTATGCCTCCCACCGTAGTTATCGGACTAATCGCCGGAGGAGATACCGCCTTGCGCAATCC
CGTCGAGAATGCGGAAGATGATATGTCCCGCGGATGGGAAGAGTTATTGCAGCATCATATCAATAGTGAAGATACAGTCA
TCGGAATTGCAGCATCCGGCACCACTCCTTATGTGATCGGAGCCATGCGCACAGCACGGGAACACGGAATACTGACCGGC
TGCATTACCAGTAATCCAAATTCGCCGATGGCTACCGAAGCTGATGTACCGATAGAAGTGATTGTCGGTCCGGAGTATGT
GACAGGAAGTTCTCGGATGAAATCGGGTACTGCTCAAAAGATGATTCTGAATATGATCAGCACTACTATCATGATTGAAC
TGGGACGCGTGCAAGGAAATAAAATGGTCAATATGCAATTGAGTAACCAAAAACTCATTGATCGGGGAACGCGCATGATC
ATTGAAGAACTCCATCTGGACTACGAAAAGGCTGAGGCACTTCTGTTGCTACACGGTTCGGTTAAGTCTGCGATAGAGGC
CTATCGCAGACACAACTCTACTCAGCAAGAGTAA

Upstream 100 bases:

>100_bases
TCATGTATACAAGTATCCCGCCCGCATCCCGGATTTTCCGAGGATTTGGATGCTACCTTGGAGCGTTTGTTCAAAGAATT
AGTGCTTTAAATGATCAATC

Downstream 100 bases:

>100_bases
AATGCAGTGCAGCACCACCGGAGGACTTTAACTTCAAAGTTAGCTTATCTCCGGCTTTTATCTTCTTATGAGTAGTACGA
ACCTTTGTACGTGTATTCAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MEFIKITEQPSLYDDLDKKSVKEILEDINTEDHKVADAVQKAIPQIEKLVTLIIPRVKKGGRIFYMGAGTSGRLGVLDAS
EIPPTFGMPPTVVIGLIAGGDTALRNPVENAEDDMSRGWEELLQHHINSEDTVIGIAASGTTPYVIGAMRTAREHGILTG
CITSNPNSPMATEADVPIEVIVGPEYVTGSSRMKSGTAQKMILNMISTTIMIELGRVQGNKMVNMQLSNQKLIDRGTRMI
IEELHLDYEKAEALLLLHGSVKSAIEAYRRHNSTQQE

Sequences:

>Translated_277_residues
MEFIKITEQPSLYDDLDKKSVKEILEDINTEDHKVADAVQKAIPQIEKLVTLIIPRVKKGGRIFYMGAGTSGRLGVLDAS
EIPPTFGMPPTVVIGLIAGGDTALRNPVENAEDDMSRGWEELLQHHINSEDTVIGIAASGTTPYVIGAMRTAREHGILTG
CITSNPNSPMATEADVPIEVIVGPEYVTGSSRMKSGTAQKMILNMISTTIMIELGRVQGNKMVNMQLSNQKLIDRGTRMI
IEELHLDYEKAEALLLLHGSVKSAIEAYRRHNSTQQE
>Mature_277_residues
MEFIKITEQPSLYDDLDKKSVKEILEDINTEDHKVADAVQKAIPQIEKLVTLIIPRVKKGGRIFYMGAGTSGRLGVLDAS
EIPPTFGMPPTVVIGLIAGGDTALRNPVENAEDDMSRGWEELLQHHINSEDTVIGIAASGTTPYVIGAMRTAREHGILTG
CITSNPNSPMATEADVPIEVIVGPEYVTGSSRMKSGTAQKMILNMISTTIMIELGRVQGNKMVNMQLSNQKLIDRGTRMI
IEELHLDYEKAEALLLLHGSVKSAIEAYRRHNSTQQE

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=268, Percent_Identity=46.2686567164179, Blast_Score=223, Evalue=9e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_BACTN (Q8ABH7)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_809046.1
- HSSP:   P44862
- ProteinModelPortal:   Q8ABH7
- SMR:   Q8ABH7
- GeneID:   1072843
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_0133
- NMPDR:   fig|226186.1.peg.133
- HOGENOM:   HBG703490
- OMA:   SMIGVGK
- PhylomeDB:   Q8ABH7
- ProtClustDB:   PRK05441
- BioCyc:   BTHE226186:BT_0133-MONOMER
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 30334; Mature: 30334

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 81-81 ACT_SITE 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFIKITEQPSLYDDLDKKSVKEILEDINTEDHKVADAVQKAIPQIEKLVTLIIPRVKKG
CCCEEECCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRIFYMGAGTSGRLGVLDASEIPPTFGMPPTVVIGLIAGGDTALRNPVENAEDDMSRGWE
CEEEEEECCCCCCEEECCCCCCCCCCCCCHHHEEEEEECCCHHHCCCCCCHHHHHHHHHH
ELLQHHINSEDTVIGIAASGTTPYVIGAMRTAREHGILTGCITSNPNSPMATEADVPIEV
HHHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEE
IVGPEYVTGSSRMKSGTAQKMILNMISTTIMIELGRVQGNKMVNMQLSNQKLIDRGTRMI
EECCCEECCCHHHCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEEEECCHHHHHHHHHHH
IEELHLDYEKAEALLLLHGSVKSAIEAYRRHNSTQQE
HHHHHCCHHHCCEEEEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFIKITEQPSLYDDLDKKSVKEILEDINTEDHKVADAVQKAIPQIEKLVTLIIPRVKKG
CCCEEECCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRIFYMGAGTSGRLGVLDASEIPPTFGMPPTVVIGLIAGGDTALRNPVENAEDDMSRGWE
CEEEEEECCCCCCEEECCCCCCCCCCCCCHHHEEEEEECCCHHHCCCCCCHHHHHHHHHH
ELLQHHINSEDTVIGIAASGTTPYVIGAMRTAREHGILTGCITSNPNSPMATEADVPIEV
HHHHHHCCCCCCEEEEEECCCCCEEHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEE
IVGPEYVTGSSRMKSGTAQKMILNMISTTIMIELGRVQGNKMVNMQLSNQKLIDRGTRMI
EECCCEECCCHHHCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEEEECCHHHHHHHHHHH
IEELHLDYEKAEALLLLHGSVKSAIEAYRRHNSTQQE
HHHHHCCHHHCCEEEEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928