| Definition | Bacteroides thetaiotaomicron VPI-5482 chromosome, complete genome. |
|---|---|
| Accession | NC_004663 |
| Length | 6,260,361 |
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The map label for this gene is uxuB [H]
Identifier: 29345540
GI number: 29345540
Start: 125549
End: 126364
Strand: Reverse
Name: uxuB [H]
Synonym: BT_0130
Alternate gene names: 29345540
Gene position: 126364-125549 (Counterclockwise)
Preceding gene: 29345543
Following gene: 29345539
Centisome position: 2.02
GC content: 46.08
Gene sequence:
>816_bases ATGAACGAATTATTTAGTATTGCCGGTAAGGTAGCTGTAATTACCGGAGCAGGTGGTGTGTTGGGAGGAAATATCGCCCA GCACTTTGTACAGCAGGGAGCAAAAGTTGTAGCTATCGACATCCGTCAGGAACAACTGGACAACCGTGTAGCAGAACTTA AACAATATGGTCAGGATGTTATCGGTATTATTGGAGACGTGCTGGACATCGCCAGTCTGGAAAAAGTAGCGGAAGAGATT GTTGCCCAATGGGGACAGATTGATATTCTGTTGAATATTGCCGGAGGCAACATGCCGGGAGCCACTCTTGAATCGGATCA GAACTTCTATGATATGGACATTTCCTGTTGGGAGAAAGTGACCAGTCTGAATATGAACGGTACAGTCTATCCGTCTATGA TCTTTGGTAAAGTGATGGCAGAGCAGAAAAAAGGTTGCATTATCAATGTGTCTTCTATGGCTGCTTATAGTGCCATCACC CGTGTGCCGGGGTATTCGGCTGCAAAAACAGCTGTAGCTAACTTTACACAATGGCTTGCCAGTGAGATGGCTCTGAAATA TGGTGACGGCATCCGTGTAAATGCCATTGCTCCCGGTTTCTTTATCGGCGATCAGAACCGTCGCGTACTTATCAATCCGG ATGGCTCGCTGACTGACAGAAGCAAAAAGGTTTTAGCCAAGACACCGATGAACCGTTTTGGTGATATTAAAGAATTGAAC GGTGCCGTACAATTTTTGTGTAGCGAAGCTGCCAGTTTTGTAACCGGTGCAATGTTGCCTATCGACGGTGGATTCAGTGC ATTCAGCGGCGTATAA
Upstream 100 bases:
>100_bases TCGGAAAATCGCTGTAACTAACTAAATTTCAAATATTTCAAAGAACTCTTTTAGATTTTAATGGGACAGCAATGAATTCA TATAAATAATAAATAAAACC
Downstream 100 bases:
>100_bases AGAGAAGAAACTATGATGGAAAAAACATGGAGATGGTTTGGCAAGAAAGACAAGATTACCTTGCCAATGCTCCGGCAAAT AGGTGTGGAAGGGATTGTTA
Product: D-mannonate oxidoreductase
Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]
Alternate protein names: NA
Number of amino acids: Translated: 271; Mature: 271
Protein sequence:
>271_residues MNELFSIAGKVAVITGAGGVLGGNIAQHFVQQGAKVVAIDIRQEQLDNRVAELKQYGQDVIGIIGDVLDIASLEKVAEEI VAQWGQIDILLNIAGGNMPGATLESDQNFYDMDISCWEKVTSLNMNGTVYPSMIFGKVMAEQKKGCIINVSSMAAYSAIT RVPGYSAAKTAVANFTQWLASEMALKYGDGIRVNAIAPGFFIGDQNRRVLINPDGSLTDRSKKVLAKTPMNRFGDIKELN GAVQFLCSEAASFVTGAMLPIDGGFSAFSGV
Sequences:
>Translated_271_residues MNELFSIAGKVAVITGAGGVLGGNIAQHFVQQGAKVVAIDIRQEQLDNRVAELKQYGQDVIGIIGDVLDIASLEKVAEEI VAQWGQIDILLNIAGGNMPGATLESDQNFYDMDISCWEKVTSLNMNGTVYPSMIFGKVMAEQKKGCIINVSSMAAYSAIT RVPGYSAAKTAVANFTQWLASEMALKYGDGIRVNAIAPGFFIGDQNRRVLINPDGSLTDRSKKVLAKTPMNRFGDIKELN GAVQFLCSEAASFVTGAMLPIDGGFSAFSGV >Mature_271_residues MNELFSIAGKVAVITGAGGVLGGNIAQHFVQQGAKVVAIDIRQEQLDNRVAELKQYGQDVIGIIGDVLDIASLEKVAEEI VAQWGQIDILLNIAGGNMPGATLESDQNFYDMDISCWEKVTSLNMNGTVYPSMIFGKVMAEQKKGCIINVSSMAAYSAIT RVPGYSAAKTAVANFTQWLASEMALKYGDGIRVNAIAPGFFIGDQNRRVLINPDGSLTDRSKKVLAKTPMNRFGDIKELN GAVQFLCSEAASFVTGAMLPIDGGFSAFSGV
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=30.3846153846154, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI32483357, Length=271, Percent_Identity=30.9963099630996, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI7705925, Length=266, Percent_Identity=27.8195488721804, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI33667109, Length=221, Percent_Identity=31.2217194570136, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=29.8850574712644, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=270, Percent_Identity=27.037037037037, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=29.5019157088123, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI4503301, Length=261, Percent_Identity=29.1187739463602, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI40254992, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=26.8382352941176, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=24.6212121212121, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI142976729, Length=212, Percent_Identity=25.9433962264151, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI4503817, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=27.9850746268657, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=28.8702928870293, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=195, Percent_Identity=24.1025641025641, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=29.1457286432161, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI224922801, Length=190, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=31.8181818181818, Blast_Score=119, Evalue=3e-28, Organism=Escherichia coli, GI1790717, Length=265, Percent_Identity=31.6981132075472, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=31.2741312741313, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=32.03125, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082160, Length=268, Percent_Identity=30.2238805970149, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI87082100, Length=273, Percent_Identity=32.6007326007326, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1788459, Length=260, Percent_Identity=28.0769230769231, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1786812, Length=266, Percent_Identity=27.4436090225564, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=264, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=24.5136186770428, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=25.8426966292135, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI2367365, Length=262, Percent_Identity=27.4809160305344, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI2367175, Length=124, Percent_Identity=34.6774193548387, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI115534694, Length=263, Percent_Identity=28.5171102661597, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI25147288, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=28.4615384615385, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=30.5343511450382, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=29.5019157088123, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=28.3524904214559, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=29.3233082706767, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560220, Length=279, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17551412, Length=284, Percent_Identity=28.8732394366197, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17563726, Length=276, Percent_Identity=28.6231884057971, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17538182, Length=279, Percent_Identity=29.3906810035842, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=30.5343511450382, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=26.7399267399267, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562908, Length=205, Percent_Identity=31.7073170731707, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17560150, Length=196, Percent_Identity=27.0408163265306, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536651, Length=274, Percent_Identity=27.3722627737226, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560332, Length=194, Percent_Identity=30.4123711340206, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=26.3959390862944, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=24.9097472924188, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=24.7272727272727, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=25, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17544670, Length=280, Percent_Identity=26.0714285714286, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI71997099, Length=248, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562904, Length=205, Percent_Identity=29.7560975609756, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17562910, Length=282, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=28.1481481481481, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=26.0536398467433, Blast_Score=80, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=32.0197044334975, Blast_Score=64, Evalue=4e-11, Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=30.9160305343511, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI23397609, Length=266, Percent_Identity=30.8270676691729, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=32.6996197718631, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI24644339, Length=274, Percent_Identity=31.021897810219, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI28571526, Length=275, Percent_Identity=30.5454545454545, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21357041, Length=271, Percent_Identity=28.7822878228782, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=30.5343511450382, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24643142, Length=264, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24649181, Length=197, Percent_Identity=24.8730964467005, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007236, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI221331218, Length=255, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665243, Length=255, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI17737361, Length=267, Percent_Identity=26.2172284644195, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=255, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665247, Length=204, Percent_Identity=28.921568627451, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.125 [C]
Molecular weight: Translated: 28897; Mature: 28897
Theoretical pI: Translated: 4.76; Mature: 4.76
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNELFSIAGKVAVITGAGGVLGGNIAQHFVQQGAKVVAIDIRQEQLDNRVAELKQYGQDV CCCHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH IGIIGDVLDIASLEKVAEEIVAQWGQIDILLNIAGGNMPGATLESDQNFYDMDISCWEKV HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHH TSLNMNGTVYPSMIFGKVMAEQKKGCIINVSSMAAYSAITRVPGYSAAKTAVANFTQWLA HHCCCCCEECHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH SEMALKYGDGIRVNAIAPGFFIGDQNRRVLINPDGSLTDRSKKVLAKTPMNRFGDIKELN HHHHHHCCCCEEEEEECCEEEECCCCCEEEECCCCCCCHHHHHHHHHCCHHHCCCHHHHH GAVQFLCSEAASFVTGAMLPIDGGFSAFSGV HHHHHHHHHHHHHHHCCCEECCCCCHHHCCC >Mature Secondary Structure MNELFSIAGKVAVITGAGGVLGGNIAQHFVQQGAKVVAIDIRQEQLDNRVAELKQYGQDV CCCHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHH IGIIGDVLDIASLEKVAEEIVAQWGQIDILLNIAGGNMPGATLESDQNFYDMDISCWEKV HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHH TSLNMNGTVYPSMIFGKVMAEQKKGCIINVSSMAAYSAITRVPGYSAAKTAVANFTQWLA HHCCCCCEECHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH SEMALKYGDGIRVNAIAPGFFIGDQNRRVLINPDGSLTDRSKKVLAKTPMNRFGDIKELN HHHHHHCCCCEEEEEECCEEEECCCCCEEEECCCCCCCHHHHHHHHHCCHHHCCCHHHHH GAVQFLCSEAASFVTGAMLPIDGGFSAFSGV HHHHHHHHHHHHHHHCCCEECCCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+ [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 15.4 {2-deoxygluconate}} [C]
Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]
Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9579062; 9384377 [H]