| Definition | Lactobacillus plantarum WCFS1, complete genome. |
|---|---|
| Accession | NC_004567 |
| Length | 3,308,274 |
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The map label for this gene is dxs [H]
Identifier: 28379134
GI number: 28379134
Start: 2328604
End: 2330355
Strand: Direct
Name: dxs [H]
Synonym: lp_2610
Alternate gene names: 28379134
Gene position: 2328604-2330355 (Clockwise)
Preceding gene: 28379133
Following gene: 28379135
Centisome position: 70.39
GC content: 47.89
Gene sequence:
>1752_bases ATGGAAACACCGATTTTAGCACGCATTGATCAGCCGGCCGATCTGAAACAATTATCCTTGCCGGAATTAACACAACTCGC AAGCGAGTTACGTCACGTCCTACTCAATAAAGTTAGTCAAACTGGTGGTCACGTTGGCCCTAACTTGGGCGTAGTCGAAT TAACCATTGCCTTTCACACCATTTTTAATTCACCAGTTGATAAGGTTGTATGGGATGTTTCACACCAATCCTACACACAC AAGATTCTAACGGGCCGAAAGCAAGCTTGGCTTGACCCCGCTCATTATAATGATGTCAGCGGCTACACTACCCCAGAAGA AAGCCCCCACGACTATTTCAATATTGGTCATACTTCAACCTCGATTGCCTTGGCAACTGGCATGGCTGTTGCTCGTGACC TTGAGGGCAAAACAGGCAATGTCATGGCAGTGATTGGTGACGGCTCATTATCCGGTGGTTTAGCATTGGAAGGTCTAAAC ATCGCGGCCACCTTAAAGTCTAACCTCATTATTCTGGTTAACGATAATGGCATGGCAATTGCAGAAGACCATGGTGGCAT TTACCAAAATCTCCGTGAACTCCGCGAAACTAACGGCACGAGTTCCCATAACTTGTTCAAAGATTTTGGCCTCGATTATC GCTACGTTGATGATGGTAACGACCTTGAGACCATGCTAACGACTTTTAAGGAAATTAAGGATGTTGACCACCCAATCGTG TTGCACGTCCATACCGAAAAGGGTCACGGCTATCAACCCGCGATCACTAATAAAGAAGCTTTCCACTGGCACGTGCCGTT TGACCTAGCGACCGGTCAGACGTTGCATCCCAACACCAAGGAAACGTATACGGATGTCATTCATGCCACGTTAGCCGATG AGTTAGCAGCCAAGACGCCTATCACGGCAATTACGGCGGCTGTTCCAGGAACTTATGACCTCAAACGCTTTGCTCGCCAA TATCCAGACCGGTACTTTGACGTCGGCATTGCCGAACAAGAATCGATTACATTTGCTGCCGGACAGGCCCAACAAGGCTT ACGGCCAATCGTCTTCCATTCTGGTACCTTCTTGCAACGGGCCTATGATCAACTATCCCATGATCTTGGCATCAATAAAT TGCCCGTTACGATCATGGTTGCCGGTGGCCGCATTAACGCAGGCGATCCAACTCATCAAGGTATCTTTGACGTTGCCATG CTCAGTAATATTCCTAACTTAACTTACTTAGCGCCAACGACCAAGGAAGAACTTCAAGCCATGATGCACTGGGCTCTCCA TCAAAATAACGGTCCGGTTGCCATCCGGGTACCAAGTAATGACGTCCAGTCAGTACCTCTAGCGCCTGATTTTGACGCAA CTAAGATGCACACATTACACGCTGGTCAGCAAGTTGCTTTACTCGGTGTAGGCAGTCTCCTGCCTTTAGCAACAGCCGTG CAACAACAATTAGCTGAGCAACACATTGACGCGACGCTCATTGATCCCCGGGACATTTCTGACCCCGATACGATGACTTT GGCCAACTTAAAGGCCGACCATCAGTTAGTTGTCACGGTTGAGGAAGCCAGTCTCAGCGGTGGTTTTGGTGAAAAAGTTA GTCGCTACTATGGCAACAGCGCTATGCGCGTTCTGAACTTTGGTGCTGCCAAACGCTTTAATGACCGTGAAACAACTAAT GAACTGCGGCATGAATTTAAGCTGACCCCTGACCAAATTGTCACGGCAATTACTGATCAACTAGCAGAATAA
Upstream 100 bases:
>100_bases CATTTTTTATGATATTTTTGAAACAAAACACTTGTCTTAGAGTGGCTCTAAGGTGCTAATCTATAAAAGTATTCATGAAT GAGAAAGTGAGCGATAGATA
Downstream 100 bases:
>100_bases TCATCAGGCCAGCGACTCAACTTTCGTTTACCCACCAAAAGTCTAGCCAGTATGTTGTCGAACTCAACACGCTGGCTAGA CTTTTTATATTTAACTGACA
Product: 1-deoxy-D-xylulose-5-phosphate synthase
Products: NA
Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]
Number of amino acids: Translated: 583; Mature: 583
Protein sequence:
>583_residues METPILARIDQPADLKQLSLPELTQLASELRHVLLNKVSQTGGHVGPNLGVVELTIAFHTIFNSPVDKVVWDVSHQSYTH KILTGRKQAWLDPAHYNDVSGYTTPEESPHDYFNIGHTSTSIALATGMAVARDLEGKTGNVMAVIGDGSLSGGLALEGLN IAATLKSNLIILVNDNGMAIAEDHGGIYQNLRELRETNGTSSHNLFKDFGLDYRYVDDGNDLETMLTTFKEIKDVDHPIV LHVHTEKGHGYQPAITNKEAFHWHVPFDLATGQTLHPNTKETYTDVIHATLADELAAKTPITAITAAVPGTYDLKRFARQ YPDRYFDVGIAEQESITFAAGQAQQGLRPIVFHSGTFLQRAYDQLSHDLGINKLPVTIMVAGGRINAGDPTHQGIFDVAM LSNIPNLTYLAPTTKEELQAMMHWALHQNNGPVAIRVPSNDVQSVPLAPDFDATKMHTLHAGQQVALLGVGSLLPLATAV QQQLAEQHIDATLIDPRDISDPDTMTLANLKADHQLVVTVEEASLSGGFGEKVSRYYGNSAMRVLNFGAAKRFNDRETTN ELRHEFKLTPDQIVTAITDQLAE
Sequences:
>Translated_583_residues METPILARIDQPADLKQLSLPELTQLASELRHVLLNKVSQTGGHVGPNLGVVELTIAFHTIFNSPVDKVVWDVSHQSYTH KILTGRKQAWLDPAHYNDVSGYTTPEESPHDYFNIGHTSTSIALATGMAVARDLEGKTGNVMAVIGDGSLSGGLALEGLN IAATLKSNLIILVNDNGMAIAEDHGGIYQNLRELRETNGTSSHNLFKDFGLDYRYVDDGNDLETMLTTFKEIKDVDHPIV LHVHTEKGHGYQPAITNKEAFHWHVPFDLATGQTLHPNTKETYTDVIHATLADELAAKTPITAITAAVPGTYDLKRFARQ YPDRYFDVGIAEQESITFAAGQAQQGLRPIVFHSGTFLQRAYDQLSHDLGINKLPVTIMVAGGRINAGDPTHQGIFDVAM LSNIPNLTYLAPTTKEELQAMMHWALHQNNGPVAIRVPSNDVQSVPLAPDFDATKMHTLHAGQQVALLGVGSLLPLATAV QQQLAEQHIDATLIDPRDISDPDTMTLANLKADHQLVVTVEEASLSGGFGEKVSRYYGNSAMRVLNFGAAKRFNDRETTN ELRHEFKLTPDQIVTAITDQLAE >Mature_583_residues METPILARIDQPADLKQLSLPELTQLASELRHVLLNKVSQTGGHVGPNLGVVELTIAFHTIFNSPVDKVVWDVSHQSYTH KILTGRKQAWLDPAHYNDVSGYTTPEESPHDYFNIGHTSTSIALATGMAVARDLEGKTGNVMAVIGDGSLSGGLALEGLN IAATLKSNLIILVNDNGMAIAEDHGGIYQNLRELRETNGTSSHNLFKDFGLDYRYVDDGNDLETMLTTFKEIKDVDHPIV LHVHTEKGHGYQPAITNKEAFHWHVPFDLATGQTLHPNTKETYTDVIHATLADELAAKTPITAITAAVPGTYDLKRFARQ YPDRYFDVGIAEQESITFAAGQAQQGLRPIVFHSGTFLQRAYDQLSHDLGINKLPVTIMVAGGRINAGDPTHQGIFDVAM LSNIPNLTYLAPTTKEELQAMMHWALHQNNGPVAIRVPSNDVQSVPLAPDFDATKMHTLHAGQQVALLGVGSLLPLATAV QQQLAEQHIDATLIDPRDISDPDTMTLANLKADHQLVVTVEEASLSGGFGEKVSRYYGNSAMRVLNFGAAKRFNDRETTN ELRHEFKLTPDQIVTAITDQLAE
Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]
COG id: COG1154
COG function: function code HI; Deoxyxylulose-5-phosphate synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transketolase family. DXPS subfamily [H]
Homologues:
Organism=Homo sapiens, GI225637463, Length=477, Percent_Identity=24.9475890985325, Blast_Score=83, Evalue=7e-16, Organism=Homo sapiens, GI225637461, Length=477, Percent_Identity=24.9475890985325, Blast_Score=83, Evalue=8e-16, Organism=Homo sapiens, GI225637459, Length=477, Percent_Identity=24.9475890985325, Blast_Score=83, Evalue=9e-16, Organism=Homo sapiens, GI133778974, Length=540, Percent_Identity=24.0740740740741, Blast_Score=80, Evalue=5e-15, Organism=Escherichia coli, GI1786622, Length=619, Percent_Identity=35.2180936995153, Blast_Score=365, Evalue=1e-102,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005477 - InterPro: IPR011766 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005475 - InterPro: IPR005476 - InterPro: IPR005474 [H]
Pfam domain/function: PF02775 TPP_enzyme_C; PF02779 Transket_pyr; PF02780 Transketolase_C [H]
EC number: =2.2.1.7 [H]
Molecular weight: Translated: 63779; Mature: 63779
Theoretical pI: Translated: 5.56; Mature: 5.56
Prosite motif: PS00801 TRANSKETOLASE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure METPILARIDQPADLKQLSLPELTQLASELRHVLLNKVSQTGGHVGPNLGVVELTIAFHT CCCCCEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHH IFNSPVDKVVWDVSHQSYTHKILTGRKQAWLDPAHYNDVSGYTTPEESPHDYFNIGHTST HHCCCHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCC SIALATGMAVARDLEGKTGNVMAVIGDGSLSGGLALEGLNIAATLKSNLIILVNDNGMAI HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCEEEEEECCCEEEEECCCCEEE AEDHGGIYQNLRELRETNGTSSHNLFKDFGLDYRYVDDGNDLETMLTTFKEIKDVDHPIV ECCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCEE LHVHTEKGHGYQPAITNKEAFHWHVPFDLATGQTLHPNTKETYTDVIHATLADELAAKTP EEEECCCCCCCCCCCCCCCCEEEECCEEECCCCEECCCCHHHHHHHHHHHHHHHHHHCCC ITAITAAVPGTYDLKRFARQYPDRYFDVGIAEQESITFAAGQAQQGLRPIVFHSGTFLQR CCEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEECCCHHHCCCEEEEECCHHHHH AYDQLSHDLGINKLPVTIMVAGGRINAGDPTHQGIFDVAMLSNIPNLTYLAPTTKEELQA HHHHHHHHCCCCCCCEEEEEECCEECCCCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHH MMHWALHQNNGPVAIRVPSNDVQSVPLAPDFDATKMHTLHAGQQVALLGVGSLLPLATAV HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHH QQQLAEQHIDATLIDPRDISDPDTMTLANLKADHQLVVTVEEASLSGGFGEKVSRYYGNS HHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCC AMRVLNFGAAKRFNDRETTNELRHEFKLTPDQIVTAITDQLAE HHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCC >Mature Secondary Structure METPILARIDQPADLKQLSLPELTQLASELRHVLLNKVSQTGGHVGPNLGVVELTIAFHT CCCCCEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHH IFNSPVDKVVWDVSHQSYTHKILTGRKQAWLDPAHYNDVSGYTTPEESPHDYFNIGHTST HHCCCHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCC SIALATGMAVARDLEGKTGNVMAVIGDGSLSGGLALEGLNIAATLKSNLIILVNDNGMAI HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCEEEEEECCCEEEEECCCCEEE AEDHGGIYQNLRELRETNGTSSHNLFKDFGLDYRYVDDGNDLETMLTTFKEIKDVDHPIV ECCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCEE LHVHTEKGHGYQPAITNKEAFHWHVPFDLATGQTLHPNTKETYTDVIHATLADELAAKTP EEEECCCCCCCCCCCCCCCCEEEECCEEECCCCEECCCCHHHHHHHHHHHHHHHHHHCCC ITAITAAVPGTYDLKRFARQYPDRYFDVGIAEQESITFAAGQAQQGLRPIVFHSGTFLQR CCEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCEEEECCCHHHCCCEEEEECCHHHHH AYDQLSHDLGINKLPVTIMVAGGRINAGDPTHQGIFDVAMLSNIPNLTYLAPTTKEELQA HHHHHHHHCCCCCCCEEEEEECCEECCCCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHH MMHWALHQNNGPVAIRVPSNDVQSVPLAPDFDATKMHTLHAGQQVALLGVGSLLPLATAV HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHH QQQLAEQHIDATLIDPRDISDPDTMTLANLKADHQLVVTVEEASLSGGFGEKVSRYYGNS HHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHCCC AMRVLNFGAAKRFNDRETTNELRHEFKLTPDQIVTAITDQLAE HHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA