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The map label for this gene is rnh [H]

Identifier: 28379120

GI number: 28379120

Start: 2310574

End: 2311470

Strand: Direct

Name: rnh [H]

Synonym: lp_2593

Alternate gene names: 28379120

Gene position: 2310574-2311470 (Clockwise)

Preceding gene: 28379119

Following gene: 28379124

Centisome position: 69.84

GC content: 49.83

Gene sequence:

>897_bases
ATGGCACAAAAATATTACGCTGTTCGTAAGGGACGCCAACCTGGTATTTACCGCACCTGGCCCGAAACTCAAAAGCAAGT
TAGCGGTTATCCACAAGCACAGTATAAGAGCTTCACAAGCGAGAAAGACGCTCAGGATTTTATGGCTGGTAAGGCCAGTC
CAACCCGGCCAGCTCACTCAAAATCAATATCTAATCAAACGCCGGTCAACGCAGCCATTACTGTTTATACTGATGGCGGT
TCGCGAAATACCGGAAACGTTGCCGGTCAGCACGTGCACCAAGATGATAAGGCTGCCTGGGCTTATCGGATTGAAATGCC
CGACCAACTCGTCACTGACTCTGCCGGCGAATGGGGTGCCACCAATAATCGCATGGAAATCATGGCCTTCTTACGAGCTC
TTGAACAATTGCAACAGCTTGGCCAAACTAAGACTGGGATTCTGTTCGTACTTGATTCACAGTATGTCCTTAACGCAGTC
ACTAAGGGCTGGCTGGCTGGTTGGAAACGACGCGGCTGGAAACGCAGCAATGGTCCGTTAGTTAACGCTGAGTTATGGCG
TGAAGTCGACCGGTTGCTTCCAGCATTCACTGCACTTAATTACCGCTGGACTAAGGGCCACGCTACCAATCAGGGCAATG
TCTTTGTCGATCATTTGTTGAATCAAACTATGGATCAAATGCACGCTGGTCAGCCGGCCCAAGCCTCGACTGGTGCTAAA
ATTAGTCCACAGCCAGCTAAAACTAGTGTGCCACAGCCGACTATGTCGAACCCAACACCAACTAAGTCTAATCAATCGGC
CACTGTACGCTCGACACCAGCTGAAAAAAAGCCAGTTGATCCCGAACAAGTCGCCCGTTCAGTAGCGGCGATCAAGAAGA
TGCTACGCGATAACTAA

Upstream 100 bases:

>100_bases
CCGGTTGTTATTATTTATTTACAAGTCTGCTAATTTTTCATTTTTCCCCGGCAATTTATGTTAAATTAGCAGTATCACCA
TTCAGAAAGTAGGTATCGCC

Downstream 100 bases:

>100_bases
TGTGCTGCACGCGAACTCAAGATGATACCGAAGTACACTCAAAAAGTTAACCAATCTAGTACTCAGTCTCGCAATTAGAT
TAGAGCACGTCTCTGCTGTC

Product: ribonuclease H (putative)

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MAQKYYAVRKGRQPGIYRTWPETQKQVSGYPQAQYKSFTSEKDAQDFMAGKASPTRPAHSKSISNQTPVNAAITVYTDGG
SRNTGNVAGQHVHQDDKAAWAYRIEMPDQLVTDSAGEWGATNNRMEIMAFLRALEQLQQLGQTKTGILFVLDSQYVLNAV
TKGWLAGWKRRGWKRSNGPLVNAELWREVDRLLPAFTALNYRWTKGHATNQGNVFVDHLLNQTMDQMHAGQPAQASTGAK
ISPQPAKTSVPQPTMSNPTPTKSNQSATVRSTPAEKKPVDPEQVARSVAAIKKMLRDN

Sequences:

>Translated_298_residues
MAQKYYAVRKGRQPGIYRTWPETQKQVSGYPQAQYKSFTSEKDAQDFMAGKASPTRPAHSKSISNQTPVNAAITVYTDGG
SRNTGNVAGQHVHQDDKAAWAYRIEMPDQLVTDSAGEWGATNNRMEIMAFLRALEQLQQLGQTKTGILFVLDSQYVLNAV
TKGWLAGWKRRGWKRSNGPLVNAELWREVDRLLPAFTALNYRWTKGHATNQGNVFVDHLLNQTMDQMHAGQPAQASTGAK
ISPQPAKTSVPQPTMSNPTPTKSNQSATVRSTPAEKKPVDPEQVARSVAAIKKMLRDN
>Mature_297_residues
AQKYYAVRKGRQPGIYRTWPETQKQVSGYPQAQYKSFTSEKDAQDFMAGKASPTRPAHSKSISNQTPVNAAITVYTDGGS
RNTGNVAGQHVHQDDKAAWAYRIEMPDQLVTDSAGEWGATNNRMEIMAFLRALEQLQQLGQTKTGILFVLDSQYVLNAVT
KGWLAGWKRRGWKRSNGPLVNAELWREVDRLLPAFTALNYRWTKGHATNQGNVFVDHLLNQTMDQMHAGQPAQASTGAKI
SPQPAKTSVPQPTMSNPTPTKSNQSATVRSTPAEKKPVDPEQVARSVAAIKKMLRDN

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=109, Percent_Identity=39.4495412844037, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115532542, Length=247, Percent_Identity=29.5546558704453, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 33024; Mature: 32892

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKYYAVRKGRQPGIYRTWPETQKQVSGYPQAQYKSFTSEKDAQDFMAGKASPTRPAHS
CCCCHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCHH
KSISNQTPVNAAITVYTDGGSRNTGNVAGQHVHQDDKAAWAYRIEMPDQLVTDSAGEWGA
HCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCC
TNNRMEIMAFLRALEQLQQLGQTKTGILFVLDSQYVLNAVTKGWLAGWKRRGWKRSNGPL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCE
VNAELWREVDRLLPAFTALNYRWTKGHATNQGNVFVDHLLNQTMDQMHAGQPAQASTGAK
ECHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
ISPQPAKTSVPQPTMSNPTPTKSNQSATVRSTPAEKKPVDPEQVARSVAAIKKMLRDN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQKYYAVRKGRQPGIYRTWPETQKQVSGYPQAQYKSFTSEKDAQDFMAGKASPTRPAHS
CCCHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCHH
KSISNQTPVNAAITVYTDGGSRNTGNVAGQHVHQDDKAAWAYRIEMPDQLVTDSAGEWGA
HCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCC
TNNRMEIMAFLRALEQLQQLGQTKTGILFVLDSQYVLNAVTKGWLAGWKRRGWKRSNGPL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCE
VNAELWREVDRLLPAFTALNYRWTKGHATNQGNVFVDHLLNQTMDQMHAGQPAQASTGAK
ECHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
ISPQPAKTSVPQPTMSNPTPTKSNQSATVRSTPAEKKPVDPEQVARSVAAIKKMLRDN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA