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The map label for this gene is rsgA2

Identifier: 28378376

GI number: 28378376

Start: 1535530

End: 1536588

Strand: Direct

Name: rsgA2

Synonym: lp_1687

Alternate gene names: 28378376

Gene position: 1535530-1536588 (Clockwise)

Preceding gene: 28378375

Following gene: 28378378

Centisome position: 46.41

GC content: 49.76

Gene sequence:

>1059_bases
TTGACAATTAATTTAATTAAATATGGATTGACGACGGCGGTTCAAGCCGACTTGACTAAGGAAAACGGTCAAATACTTGG
CCGGATTATCGGCCAACATCGTGATTGGTACCAAGTCATCACGACGGCTGGGGAACGTTCAGCACAAGTTACGGGAAAAC
TGGCTTATGAAGCGGCCAGTCCCGCGGCATTTCCGGCGGTTGGGGATTGGGTGTGCCTATCTTCATCCGCTGATAATCAG
GCGCAGATTGAAGCAATCGCGCCACGGCAGAGTGTCTTGGCGCGCGGTGCCGTGAACCGCCAAGACGGCCAAATCATTGC
GACAAATATTAATACCATCTTTATCTGCATGTCATTGAACGCGGATTTTAATGTGCGGCGGTTAGAACGTTACCTGACGA
TTGCGTGGGATAGCGGTGCACTTCCGGTCATTGTCTTAACCAAGGCGGATCTCTGCACGGATCTAGCCACTAAGTTACGG
GCTGTGGCGGATGTCAGTGTCGGCGTACCAACGATCACTTGTTCGGTCGAAACGGGTCAGGGTTTGGATGAATTGCAACC
ATACCTAACGACTGGTCAAACGGTGGCCTTCGTGGGCTCTTCGGGTGTCGGTAAGTCGACTTTGATTAACCGATTGTTGG
GCCAGGATATCTTGGCGACGAAATCGATTCGTACAGATGATAACAAAGGGCGGCACACAACGACGAGTCGGCAATTAATA
CCGCTACCAACGGGCGCCTGTGTCATTGATACACCAGGAATGCGTGAGTTACAAATCTTCATGGGTGATTTAAATCAAAC
TTTCGCGGAAATTGCCGCATTGGCGACACAGTGTAAGTTTAATGATTGTACCCATACTAGCGAGCCTGGTTGTGCGGTAC
GGGCAGCAGTTGAGGTGGGCACGGTAACGTCTGAACGGTTACAAAGCTATCAAAAATTACAACGTGAAATGAGCTATCAA
GGACTCAATTCACGCCAGTTGGAGCAGGCTAAAATTCAGCGGATGTTCGGTGGCAAACAAGCGATGAAGCGTGTTAAACA
ACGTTACCATCGCGACTGA

Upstream 100 bases:

>100_bases
GACATGCCGGACGGTTTTTGCGCACAGTTGGGATAAGACTGGGCGCATTTTTAATTCGCAGAGCGTTAGGGTAAGTCACT
TTGCGAAAGGATTATAAAAA

Downstream 100 bases:

>100_bases
GTTGATAAGTAAATTAAAGAAGCTACTAAACGGGATGTCGGCAACGGCACCCCGTTTTATTTAGGACCTACTTTCGTTAT
CGCGTAGAGTGAACCGAGTG

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTINLIKYGLTTAVQADLTKENGQILGRIIGQHRDWYQVITTAGERSAQVTGKLAYEAASPAAFPAVGDWVCLSSSADNQ
AQIEAIAPRQSVLARGAVNRQDGQIIATNINTIFICMSLNADFNVRRLERYLTIAWDSGALPVIVLTKADLCTDLATKLR
AVADVSVGVPTITCSVETGQGLDELQPYLTTGQTVAFVGSSGVGKSTLINRLLGQDILATKSIRTDDNKGRHTTTSRQLI
PLPTGACVIDTPGMRELQIFMGDLNQTFAEIAALATQCKFNDCTHTSEPGCAVRAAVEVGTVTSERLQSYQKLQREMSYQ
GLNSRQLEQAKIQRMFGGKQAMKRVKQRYHRD

Sequences:

>Translated_352_residues
MTINLIKYGLTTAVQADLTKENGQILGRIIGQHRDWYQVITTAGERSAQVTGKLAYEAASPAAFPAVGDWVCLSSSADNQ
AQIEAIAPRQSVLARGAVNRQDGQIIATNINTIFICMSLNADFNVRRLERYLTIAWDSGALPVIVLTKADLCTDLATKLR
AVADVSVGVPTITCSVETGQGLDELQPYLTTGQTVAFVGSSGVGKSTLINRLLGQDILATKSIRTDDNKGRHTTTSRQLI
PLPTGACVIDTPGMRELQIFMGDLNQTFAEIAALATQCKFNDCTHTSEPGCAVRAAVEVGTVTSERLQSYQKLQREMSYQ
GLNSRQLEQAKIQRMFGGKQAMKRVKQRYHRD
>Mature_351_residues
TINLIKYGLTTAVQADLTKENGQILGRIIGQHRDWYQVITTAGERSAQVTGKLAYEAASPAAFPAVGDWVCLSSSADNQA
QIEAIAPRQSVLARGAVNRQDGQIIATNINTIFICMSLNADFNVRRLERYLTIAWDSGALPVIVLTKADLCTDLATKLRA
VADVSVGVPTITCSVETGQGLDELQPYLTTGQTVAFVGSSGVGKSTLINRLLGQDILATKSIRTDDNKGRHTTTSRQLIP
LPTGACVIDTPGMRELQIFMGDLNQTFAEIAALATQCKFNDCTHTSEPGCAVRAAVEVGTVTSERLQSYQKLQREMSYQG
LNSRQLEQAKIQRMFGGKQAMKRVKQRYHRD

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=244, Percent_Identity=35.655737704918, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA2_LACPL (Q88WF3)

Other databases:

- EMBL:   AL935256
- RefSeq:   NP_785268.1
- ProteinModelPortal:   Q88WF3
- SMR:   Q88WF3
- GeneID:   1061738
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1687
- NMPDR:   fig|220668.1.peg.1402
- HOGENOM:   HBG652450
- OMA:   FPAVGDW
- BioCyc:   LPLA220668:LP_1687-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR016027
- InterPro:   IPR004881
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 38312; Mature: 38181

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINLIKYGLTTAVQADLTKENGQILGRIIGQHRDWYQVITTAGERSAQVTGKLAYEAAS
CEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHEEEEEEECCCC
PAAFPAVGDWVCLSSSADNQAQIEAIAPRQSVLARGAVNRQDGQIIATNINTIFICMSLN
CCCCCCCCCEEEECCCCCCCEEEEEECCHHHHHHHCCCCCCCCEEEEEECCEEEEEEECC
ADFNVRRLERYLTIAWDSGALPVIVLTKADLCTDLATKLRAVADVSVGVPTITCSVETGQ
CCCCHHEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GLDELQPYLTTGQTVAFVGSSGVGKSTLINRLLGQDILATKSIRTDDNKGRHTTTSRQLI
CHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCEECCCCEEE
PLPTGACVIDTPGMRELQIFMGDLNQTFAEIAALATQCKFNDCTHTSEPGCAVRAAVEVG
ECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHC
TVTSERLQSYQKLQREMSYQGLNSRQLEQAKIQRMFGGKQAMKRVKQRYHRD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TINLIKYGLTTAVQADLTKENGQILGRIIGQHRDWYQVITTAGERSAQVTGKLAYEAAS
EEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHEEEEEEECCCC
PAAFPAVGDWVCLSSSADNQAQIEAIAPRQSVLARGAVNRQDGQIIATNINTIFICMSLN
CCCCCCCCCEEEECCCCCCCEEEEEECCHHHHHHHCCCCCCCCEEEEEECCEEEEEEECC
ADFNVRRLERYLTIAWDSGALPVIVLTKADLCTDLATKLRAVADVSVGVPTITCSVETGQ
CCCCHHEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GLDELQPYLTTGQTVAFVGSSGVGKSTLINRLLGQDILATKSIRTDDNKGRHTTTSRQLI
CHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCEECCCCEEE
PLPTGACVIDTPGMRELQIFMGDLNQTFAEIAALATQCKFNDCTHTSEPGCAVRAAVEVG
ECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHC
TVTSERLQSYQKLQREMSYQGLNSRQLEQAKIQRMFGGKQAMKRVKQRYHRD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566