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The map label for this gene is opuD [H]

Identifier: 28378310

GI number: 28378310

Start: 1464195

End: 1464848

Strand: Direct

Name: opuD [H]

Synonym: lp_1610

Alternate gene names: 28378310

Gene position: 1464195-1464848 (Clockwise)

Preceding gene: 28378309

Following gene: 28378312

Centisome position: 44.26

GC content: 45.11

Gene sequence:

>654_bases
ATGGCTCAGATGAACTTACTGCAACAGTTGATATATTATTACCAACAAAACGGTGTGTACGTGTTAAGCCAGTTCTCACG
TCACTTCTTGATTTCAATTTATGGCGTGCTGTTTGCGGCAATTGTTGGGATTCCAATTGGCATTTTCATTGCCCATCATA
GTCGATTGAGTGCGACAGTGATCGCGATTGCCAATGTGATTCAAACGATTCCGTCACTAGCGATGTTATCAATCATCATG
ATTGGTTTGGGCCTAGGTGTGAACACGGTAATCGTCACGGTCTTTTTATACGCGTTGCTACCGATTATCAAGAATACCTA
TACTGGAATGCAAAATGTGAGTGCTAGTATTTTAGATTCCGGTAAGGGGATGGGGATGACGCGTTGGCAATTGTTACGAA
TGGTGGAGTTGCCACTGTCACTTTCCGTCATTATGGCTGGACTCCGGAACGCATTAGTGTTGGCTATCGGGATTACGGCC
ATTGGGACCTTCGTTGGTGCCGGCGGTTTAGGGGATATCATTATTCGAGGAACCAATGCTACGAATGGTGGTGCCATTAT
CTTGGCCGGGGCGTTACCAACAGCTTTAATGGCAATCATTGCTGATACGGTCTTGGCTTGGATTGAAAAGCGTGCTGATC
CAACTCAAAAATAA

Upstream 100 bases:

>100_bases
AAAACTTGAACTATCAAGTTGATAATAACTTAGTGGAACCGGAAGTTGTGGCTAAACAGTTCCTTGAAAAACATAATTAC
TTTGAAGGGAGTGACAAATA

Downstream 100 bases:

>100_bases
CGTCAGTGAGCGACAAGTAAAAGAAGCAATATAAAAATTAAGTTACTAAAAAAGATTGATTTACAGGTACTCCGTACTCA
CTCATTCAGGGAAGTCAGTG

Product: glycine betaine/carnitine/choline ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MAQMNLLQQLIYYYQQNGVYVLSQFSRHFLISIYGVLFAAIVGIPIGIFIAHHSRLSATVIAIANVIQTIPSLAMLSIIM
IGLGLGVNTVIVTVFLYALLPIIKNTYTGMQNVSASILDSGKGMGMTRWQLLRMVELPLSLSVIMAGLRNALVLAIGITA
IGTFVGAGGLGDIIIRGTNATNGGAIILAGALPTALMAIIADTVLAWIEKRADPTQK

Sequences:

>Translated_217_residues
MAQMNLLQQLIYYYQQNGVYVLSQFSRHFLISIYGVLFAAIVGIPIGIFIAHHSRLSATVIAIANVIQTIPSLAMLSIIM
IGLGLGVNTVIVTVFLYALLPIIKNTYTGMQNVSASILDSGKGMGMTRWQLLRMVELPLSLSVIMAGLRNALVLAIGITA
IGTFVGAGGLGDIIIRGTNATNGGAIILAGALPTALMAIIADTVLAWIEKRADPTQK
>Mature_216_residues
AQMNLLQQLIYYYQQNGVYVLSQFSRHFLISIYGVLFAAIVGIPIGIFIAHHSRLSATVIAIANVIQTIPSLAMLSIIMI
GLGLGVNTVIVTVFLYALLPIIKNTYTGMQNVSASILDSGKGMGMTRWQLLRMVELPLSLSVIMAGLRNALVLAIGITAI
GTFVGAGGLGDIIIRGTNATNGGAIILAGALPTALMAIIADTVLAWIEKRADPTQK

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=191, Percent_Identity=39.2670157068063, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788451, Length=220, Percent_Identity=26.8181818181818, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789033, Length=165, Percent_Identity=30.9090909090909, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23039; Mature: 22908

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMNLLQQLIYYYQQNGVYVLSQFSRHFLISIYGVLFAAIVGIPIGIFIAHHSRLSATV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIANVIQTIPSLAMLSIIMIGLGLGVNTVIVTVFLYALLPIIKNTYTGMQNVSASILDS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GKGMGMTRWQLLRMVELPLSLSVIMAGLRNALVLAIGITAIGTFVGAGGLGDIIIRGTNA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
TNGGAIILAGALPTALMAIIADTVLAWIEKRADPTQK
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQMNLLQQLIYYYQQNGVYVLSQFSRHFLISIYGVLFAAIVGIPIGIFIAHHSRLSATV
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIANVIQTIPSLAMLSIIMIGLGLGVNTVIVTVFLYALLPIIKNTYTGMQNVSASILDS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
GKGMGMTRWQLLRMVELPLSLSVIMAGLRNALVLAIGITAIGTFVGAGGLGDIIIRGTNA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
TNGGAIILAGALPTALMAIIADTVLAWIEKRADPTQK
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]