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The map label for this gene is rrp5 [H]

Identifier: 28378254

GI number: 28378254

Start: 1410354

End: 1411040

Strand: Direct

Name: rrp5 [H]

Synonym: lp_1544

Alternate gene names: 28378254

Gene position: 1410354-1411040 (Clockwise)

Preceding gene: 28378253

Following gene: 28378255

Centisome position: 42.63

GC content: 42.07

Gene sequence:

>687_bases
ATGAGTCGAATATTAATTATTGAGGATGAAAAAAACCTCGCACGCTTCGTTGAATTAGAATTAAAACACGAAGGCTATGA
TATTCAAGTCGAATATAACGGCCGTAAAGGGTTAGACGCAGCGTTAGCTGAAGATTTTGATGCCATCCTATTAGACCTGA
TGTTACCAGAACTGAACGGTTTGGAAGTCTGCCGGCGGGTTCGTGAAGTCAAGAACACGCCGATTATTATGATGACGGCC
CGTGACTCCGTGATTGATCGAGTTTCCGGCCTGGATCATGGGGCAGATGATTACATTGTTAAGCCATTTGCTATCGAAGA
ATTACTTGCCCGCTTACGAGCACTATTGCGGCGAATCGATTTGGAAAGTGAACAACAAAGCACTAAACAAACGACCGTCA
CTTATAAAGACTTGACGATTGAAAAGGAAAACTTAGTCGTTAAACGCGGCGACGAAGTCATCAACTTGACGAAGCGTGAA
TATGAACTGTTATTAACTTTAATGGAAAATATTAACGTTGTCCTCGCTCGTGATGTCTTACTAAACAAAGTATGGGGTTA
CGAATCAGAAGTTGAAACGAATGTCGTCGACGTTTATATCCGTTACTTACGGAACAAGATTGACCGACCAGGAGAAAAGA
GTTACATCCAAACTGTTCGTGGGACTGGATACGTGATTCGTTCTTAA

Upstream 100 bases:

>100_bases
AAAATAACATGTTGTACTAGCTTAATGCAGGTTAGTGGTGATAAATCACTGATTCGTACGGTTTTTAGATAAGTTGAATA
TTAGGAGTGACTAAAAGTAA

Downstream 100 bases:

>100_bases
TGACTGACGCTGATACGAATCAAGTGACGCCTAAACCACGGCGCCGTTGGTCATTAAAATGGAAATGGGCGCTCGGGACC
GCAATTGGGTCCGCGCTCAT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSRILIIEDEKNLARFVELELKHEGYDIQVEYNGRKGLDAALAEDFDAILLDLMLPELNGLEVCRRVREVKNTPIIMMTA
RDSVIDRVSGLDHGADDYIVKPFAIEELLARLRALLRRIDLESEQQSTKQTTVTYKDLTIEKENLVVKRGDEVINLTKRE
YELLLTLMENINVVLARDVLLNKVWGYESEVETNVVDVYIRYLRNKIDRPGEKSYIQTVRGTGYVIRS

Sequences:

>Translated_228_residues
MSRILIIEDEKNLARFVELELKHEGYDIQVEYNGRKGLDAALAEDFDAILLDLMLPELNGLEVCRRVREVKNTPIIMMTA
RDSVIDRVSGLDHGADDYIVKPFAIEELLARLRALLRRIDLESEQQSTKQTTVTYKDLTIEKENLVVKRGDEVINLTKRE
YELLLTLMENINVVLARDVLLNKVWGYESEVETNVVDVYIRYLRNKIDRPGEKSYIQTVRGTGYVIRS
>Mature_227_residues
SRILIIEDEKNLARFVELELKHEGYDIQVEYNGRKGLDAALAEDFDAILLDLMLPELNGLEVCRRVREVKNTPIIMMTAR
DSVIDRVSGLDHGADDYIVKPFAIEELLARLRALLRRIDLESEQQSTKQTTVTYKDLTIEKENLVVKRGDEVINLTKREY
ELLLTLMENINVVLARDVLLNKVWGYESEVETNVVDVYIRYLRNKIDRPGEKSYIQTVRGTGYVIRS

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=41.4414414414414, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=39.0350877192982, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=35.5555555555556, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=38.2222222222222, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=36.7256637168142, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=37.719298245614, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=35.2678571428571, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=32.8947368421053, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=33.4745762711864, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=34.2222222222222, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=34.4978165938865, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=32.7510917030568, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.1888412017167, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=34.8623853211009, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790437, Length=142, Percent_Identity=26.7605633802817, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26373; Mature: 26242

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILIIEDEKNLARFVELELKHEGYDIQVEYNGRKGLDAALAEDFDAILLDLMLPELNG
CCEEEEEECCCHHHHHHHEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCH
LEVCRRVREVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKPFAIEELLARLRALLRRID
HHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
LESEQQSTKQTTVTYKDLTIEKENLVVKRGDEVINLTKREYELLLTLMENINVVLARDVL
CCCHHHHHHHHEEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHH
LNKVWGYESEVETNVVDVYIRYLRNKIDRPGEKSYIQTVRGTGYVIRS
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
SRILIIEDEKNLARFVELELKHEGYDIQVEYNGRKGLDAALAEDFDAILLDLMLPELNG
CEEEEEECCCHHHHHHHEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCH
LEVCRRVREVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKPFAIEELLARLRALLRRID
HHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCC
LESEQQSTKQTTVTYKDLTIEKENLVVKRGDEVINLTKREYELLLTLMENINVVLARDVL
CCCHHHHHHHHEEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHH
LNKVWGYESEVETNVVDVYIRYLRNKIDRPGEKSYIQTVRGTGYVIRS
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA