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The map label for this gene is cshA2 [H]

Identifier: 28378253

GI number: 28378253

Start: 1408815

End: 1410191

Strand: Direct

Name: cshA2 [H]

Synonym: lp_1543

Alternate gene names: 28378253

Gene position: 1408815-1410191 (Clockwise)

Preceding gene: 28378252

Following gene: 28378254

Centisome position: 42.58

GC content: 47.57

Gene sequence:

>1377_bases
ATGCGACAAGAATCATTATTTAACCCGGATAAATCTAGTAGTAGTCCGTTGGCTTACCGGGTCCGGCCAGTGACGCTGGC
GGATTTCAAGGGCCAAGAGCATCTACTTGGCCCGGGTAAACTATTACGACAATTAATCGCAGAAGATCAGTTACCATCCC
TGATTTTTTGGGGACCACCGGGAGTCGGCAAGACCACGCTAGCCGAAATTATTGCGCAACAGACCCAGTCGCACTTTATT
ACGTTTAGCGCGGTGACGAGTGGCATTAAAGAAATTCGGCAAATCATGGATGAAGCGGAGGCTAATCGAGATTTTGGTGA
AAAGACCATTGTTTTTATTGATGAAATTCACCGGTTTAATAAAGCCCAACAAGATGCCTTTTTGCCATATGTTGAGCGCG
GCAGTATCACGTTAATTGGTGCGACGACGGAAAATCCCTCATTTGAAATTAACGCGGCCCTATTATCACGGTGCAAAGTA
TTGGTCTTAAAGGCATTGACGCCTGACGCATTAGAAGCTGTCTTACAGGGTGCTTTGCAGAATCCGAAGGGGTTTCCGGA
TCTTGAGATTACGATGCAGCCTGATACACTACGGTTGATCGCAGAATTTGCTAATGGTGATGCTCGTATGGCGCTCAATA
CGTTAGAAATGGCTGTTTTGAACGGTGACCGCGATGGCAAGCACGTTACGATTACTACGGCCGGGTTATCGCAACTGATC
AATACTAAGTCGTTGCGCTACGATAAGCATGGCGAGGAGCATTATAATATTATCTCCGCGTTACATAAATCAATGCGTAA
TAGTGATGTTGACGCGGCGATTTACTGGTTGATGCGGATGCTAGCCGGCGGTGAAGATCCGCTATATATCGCTCGGCGTT
TGATTCGGTTTGCGAGTGAGGACATTGGGCTAGCTGACCGGCAGGCATTGCCACTGACGGTAGCGGTCTTTCAGGCGTGC
CAGTTGATCGGTATGCCCGAGTGTGACGTGAATTTGACGGAAGCAGTGACTTATTTAGCCTTAGCACCGAAGTCCAATGC
ATTATACGCGGCTAAATCAGCAGCGCAAGCAGATATCAAAGCGACGGGTAATTTACCGGTCCCCTTACAGATTCGCAACG
CACCGACAAAATTAATGAAAGATTTAGGTTATGGTTCTGATTACCAATATGCCCATGATACAGCGGCCAAATTAACCACG
ATGACGACGATGCCACCTGAGTTAAAACAGCACCGGTACTATGAGCCGACTAGCCAGGGACAGGAGAAAGCCTGGCAACA
GCGCCTAGCTGCTATTCGCAGTGGCACCAGCAACATCCGCAAACCGAACCGTCAGATGATGAGACATAAAGATTGCAATT
TAATGAGAATTCACTAA

Upstream 100 bases:

>100_bases
GTGGGTGGCTGTGCGGTAATGATCGTTGGTTTGAGTGGATTAGAACGTACGTTTGCGTTAAAATTGAGAGTAATGAATAA
ACGCGAAAGTGGGGGTCGCC

Downstream 100 bases:

>100_bases
AATTAGATTTGGGTGAGGAGCAGACCCTGGTTGGGGTGTAGGAAATTCAGCGTTTTCATGTTAAAATAACATGTTGTACT
AGCTTAATGCAGGTTAGTGG

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MRQESLFNPDKSSSSPLAYRVRPVTLADFKGQEHLLGPGKLLRQLIAEDQLPSLIFWGPPGVGKTTLAEIIAQQTQSHFI
TFSAVTSGIKEIRQIMDEAEANRDFGEKTIVFIDEIHRFNKAQQDAFLPYVERGSITLIGATTENPSFEINAALLSRCKV
LVLKALTPDALEAVLQGALQNPKGFPDLEITMQPDTLRLIAEFANGDARMALNTLEMAVLNGDRDGKHVTITTAGLSQLI
NTKSLRYDKHGEEHYNIISALHKSMRNSDVDAAIYWLMRMLAGGEDPLYIARRLIRFASEDIGLADRQALPLTVAVFQAC
QLIGMPECDVNLTEAVTYLALAPKSNALYAAKSAAQADIKATGNLPVPLQIRNAPTKLMKDLGYGSDYQYAHDTAAKLTT
MTTMPPELKQHRYYEPTSQGQEKAWQQRLAAIRSGTSNIRKPNRQMMRHKDCNLMRIH

Sequences:

>Translated_458_residues
MRQESLFNPDKSSSSPLAYRVRPVTLADFKGQEHLLGPGKLLRQLIAEDQLPSLIFWGPPGVGKTTLAEIIAQQTQSHFI
TFSAVTSGIKEIRQIMDEAEANRDFGEKTIVFIDEIHRFNKAQQDAFLPYVERGSITLIGATTENPSFEINAALLSRCKV
LVLKALTPDALEAVLQGALQNPKGFPDLEITMQPDTLRLIAEFANGDARMALNTLEMAVLNGDRDGKHVTITTAGLSQLI
NTKSLRYDKHGEEHYNIISALHKSMRNSDVDAAIYWLMRMLAGGEDPLYIARRLIRFASEDIGLADRQALPLTVAVFQAC
QLIGMPECDVNLTEAVTYLALAPKSNALYAAKSAAQADIKATGNLPVPLQIRNAPTKLMKDLGYGSDYQYAHDTAAKLTT
MTTMPPELKQHRYYEPTSQGQEKAWQQRLAAIRSGTSNIRKPNRQMMRHKDCNLMRIH
>Mature_458_residues
MRQESLFNPDKSSSSPLAYRVRPVTLADFKGQEHLLGPGKLLRQLIAEDQLPSLIFWGPPGVGKTTLAEIIAQQTQSHFI
TFSAVTSGIKEIRQIMDEAEANRDFGEKTIVFIDEIHRFNKAQQDAFLPYVERGSITLIGATTENPSFEINAALLSRCKV
LVLKALTPDALEAVLQGALQNPKGFPDLEITMQPDTLRLIAEFANGDARMALNTLEMAVLNGDRDGKHVTITTAGLSQLI
NTKSLRYDKHGEEHYNIISALHKSMRNSDVDAAIYWLMRMLAGGEDPLYIARRLIRFASEDIGLADRQALPLTVAVFQAC
QLIGMPECDVNLTEAVTYLALAPKSNALYAAKSAAQADIKATGNLPVPLQIRNAPTKLMKDLGYGSDYQYAHDTAAKLTT
MTTMPPELKQHRYYEPTSQGQEKAWQQRLAAIRSGTSNIRKPNRQMMRHKDCNLMRIH

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=413, Percent_Identity=49.3946731234867, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI18426904, Length=413, Percent_Identity=44.5520581113801, Blast_Score=322, Evalue=3e-88,
Organism=Escherichia coli, GI1787119, Length=419, Percent_Identity=49.4033412887828, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6324111, Length=427, Percent_Identity=40.7494145199063, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6324039, Length=209, Percent_Identity=28.2296650717703, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 50888; Mature: 50888

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQESLFNPDKSSSSPLAYRVRPVTLADFKGQEHLLGPGKLLRQLIAEDQLPSLIFWGPP
CCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCC
GVGKTTLAEIIAQQTQSHFITFSAVTSGIKEIRQIMDEAEANRDFGEKTIVFIDEIHRFN
CCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHC
KAQQDAFLPYVERGSITLIGATTENPSFEINAALLSRCKVLVLKALTPDALEAVLQGALQ
HHHHHHCCCEEECCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NPKGFPDLEITMQPDTLRLIAEFANGDARMALNTLEMAVLNGDRDGKHVTITTAGLSQLI
CCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCCCEEEEEHHHHHHHH
NTKSLRYDKHGEEHYNIISALHKSMRNSDVDAAIYWLMRMLAGGEDPLYIARRLIRFASE
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
DIGLADRQALPLTVAVFQACQLIGMPECDVNLTEAVTYLALAPKSNALYAAKSAAQADIK
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEECCCCCCEEHHHHHHHCCCE
ATGNLPVPLQIRNAPTKLMKDLGYGSDYQYAHDTAAKLTTMTTMPPELKQHRYYEPTSQG
ECCCCCCEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCHHHHHCCCCCCCCCH
QEKAWQQRLAAIRSGTSNIRKPNRQMMRHKDCNLMRIH
HHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MRQESLFNPDKSSSSPLAYRVRPVTLADFKGQEHLLGPGKLLRQLIAEDQLPSLIFWGPP
CCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCC
GVGKTTLAEIIAQQTQSHFITFSAVTSGIKEIRQIMDEAEANRDFGEKTIVFIDEIHRFN
CCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHC
KAQQDAFLPYVERGSITLIGATTENPSFEINAALLSRCKVLVLKALTPDALEAVLQGALQ
HHHHHHCCCEEECCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NPKGFPDLEITMQPDTLRLIAEFANGDARMALNTLEMAVLNGDRDGKHVTITTAGLSQLI
CCCCCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHEEEECCCCCCCEEEEEHHHHHHHH
NTKSLRYDKHGEEHYNIISALHKSMRNSDVDAAIYWLMRMLAGGEDPLYIARRLIRFASE
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
DIGLADRQALPLTVAVFQACQLIGMPECDVNLTEAVTYLALAPKSNALYAAKSAAQADIK
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEECCCCCCEEHHHHHHHCCCE
ATGNLPVPLQIRNAPTKLMKDLGYGSDYQYAHDTAAKLTTMTTMPPELKQHRYYEPTSQG
ECCCCCCEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHEEECCCCHHHHHCCCCCCCCCH
QEKAWQQRLAAIRSGTSNIRKPNRQMMRHKDCNLMRIH
HHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]