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The map label for this gene is acm1 [H]

Identifier: 28377918

GI number: 28377918

Start: 1034984

End: 1035625

Strand: Direct

Name: acm1 [H]

Synonym: lp_1138

Alternate gene names: 28377918

Gene position: 1034984-1035625 (Clockwise)

Preceding gene: 28377916

Following gene: 28377919

Centisome position: 31.28

GC content: 47.04

Gene sequence:

>642_bases
ATGATGGCGGGTAAGCGGCGAAAATCGCGCCGGAAGCAACGGACAAAGACACAATTATTTGTGAAGAAGGGCCGCCTTCA
GTGGGTCAATATCTTATTAGTGTTGGCGGCGATGGTGGGGATGGTTTGGTATATTCAGCATAATTGGGCGGTTAAGTCGC
GGGTTACGGCGACAACACCTACAACAACGCATGCGGCATTTATTAAAAAGCTAGTACCAGCTGCGCAACAGCTTGATCAG
CAATACCACGTGCTGGCTAGTATCACGCTAAGTCAGGCGATTTTGGAATCGGATTGGGGACAAAGTACCAATGCGACAGA
GAATAATAATTTATTTGGGGTTAAGTCCAAGTCGGGACGGCTCATGACGACGCAGGAGTATTATGACGGGGCCTATCATA
CGGTCAAACGGCGCTTCGCCGTTTATGATAGCTGGCACGCTTCGCTGGTCGATCATGCCAAGAAATTGGCGTACGGAACG
ACTTGGGATTCTCAGCACTACGCTGCGGTGATTAAGGCAACTGATTATCAGACAGCTGCGCAAGCATTGCAGACGGCTGG
ATATGCGACTGATCCAAGTTATGCACAAAAATTAATTAATATTATTCAAAAATATGACTTACAACGGTATGATAGAAAGT
AA

Upstream 100 bases:

>100_bases
GCTGGCAGCTTTTGAACTAAGAAACCAGCATGTTTTAATCCTAATTCATGATAAATGAACAGGTGTAATCTGTAAGGCAA
TTACCAGAAAGGAGGCGGCT

Downstream 100 bases:

>100_bases
TGAAATTAATAGCAGTATTTCAATGTCGCTTATAATTCTAGGAGGGTACTATGCGAGAACTTGAAGAACGCATTTTGAAA
GATGGCCGGGTACTTCCCGG

Product: muramidase

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MMAGKRRKSRRKQRTKTQLFVKKGRLQWVNILLVLAAMVGMVWYIQHNWAVKSRVTATTPTTTHAAFIKKLVPAAQQLDQ
QYHVLASITLSQAILESDWGQSTNATENNNLFGVKSKSGRLMTTQEYYDGAYHTVKRRFAVYDSWHASLVDHAKKLAYGT
TWDSQHYAAVIKATDYQTAAQALQTAGYATDPSYAQKLINIIQKYDLQRYDRK

Sequences:

>Translated_213_residues
MMAGKRRKSRRKQRTKTQLFVKKGRLQWVNILLVLAAMVGMVWYIQHNWAVKSRVTATTPTTTHAAFIKKLVPAAQQLDQ
QYHVLASITLSQAILESDWGQSTNATENNNLFGVKSKSGRLMTTQEYYDGAYHTVKRRFAVYDSWHASLVDHAKKLAYGT
TWDSQHYAAVIKATDYQTAAQALQTAGYATDPSYAQKLINIIQKYDLQRYDRK
>Mature_213_residues
MMAGKRRKSRRKQRTKTQLFVKKGRLQWVNILLVLAAMVGMVWYIQHNWAVKSRVTATTPTTTHAAFIKKLVPAAQQLDQ
QYHVLASITLSQAILESDWGQSTNATENNNLFGVKSKSGRLMTTQEYYDGAYHTVKRRFAVYDSWHASLVDHAKKLAYGT
TWDSQHYAAVIKATDYQTAAQALQTAGYATDPSYAQKLINIIQKYDLQRYDRK

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=148, Percent_Identity=43.2432432432432, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 24336; Mature: 24336

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAGKRRKSRRKQRTKTQLFVKKGRLQWVNILLVLAAMVGMVWYIQHNWAVKSRVTATTP
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEECCC
TTTHAAFIKKLVPAAQQLDQQYHVLASITLSQAILESDWGQSTNATENNNLFGVKSKSGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
LMTTQEYYDGAYHTVKRRFAVYDSWHASLVDHAKKLAYGTTWDSQHYAAVIKATDYQTAA
EEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHH
QALQTAGYATDPSYAQKLINIIQKYDLQRYDRK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMAGKRRKSRRKQRTKTQLFVKKGRLQWVNILLVLAAMVGMVWYIQHNWAVKSRVTATTP
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEECCC
TTTHAAFIKKLVPAAQQLDQQYHVLASITLSQAILESDWGQSTNATENNNLFGVKSKSGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
LMTTQEYYDGAYHTVKRRFAVYDSWHASLVDHAKKLAYGTTWDSQHYAAVIKATDYQTAA
EEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHH
QALQTAGYATDPSYAQKLINIIQKYDLQRYDRK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]