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The map label for this gene is citX [H]

Identifier: 28377902

GI number: 28377902

Start: 1012455

End: 1013000

Strand: Direct

Name: citX [H]

Synonym: lp_1114

Alternate gene names: 28377902

Gene position: 1012455-1013000 (Clockwise)

Preceding gene: 28377901

Following gene: 28377903

Centisome position: 30.6

GC content: 53.11

Gene sequence:

>546_bases
GTGACAAGCATGGCGACGATTTTTACAACCGGTGAACCGCAAACAATCACGGCAATGCTAGCAGCCCGTGATCAACGGGT
CGCGTATCAGCAACAGTTGACAGCGACTAACCCCCGGGCCACGATTGCGGCGATCAAGTTGAATATTCCGGGACCGATTA
AGAATAACGCTGCACTACGACGGTTGTTTTTGGCCGGTGTCCAGCGGTTTGAAGCTGAGTTGTCGACATACACGGTGGCA
GCTGATTGGAATCATCCGGCGGGTAATGAGCGGTTCTTGATTCTGACGACTGACTTTGCGACTAGCAAACGGCTGGCGGT
CGCTTTTGAAGAACACGATCCGTTAGGTCGCTTATATGATATTGACATCTTACAAGCGGGTTCACAGCGCGCGCTGTCGC
GGACGGATTTGGGGCTGCCGAAGCGTCGTTGCTTATTATGTCACCGTGAAGCCAAGGATTGCGCGCGTTCACGGCGGCAT
TCAGTGGCTGAGCTACAGCAAAAGATTGCGGCGATGTACATGAAGGAATTTGGTGAACGCGGATGA

Upstream 100 bases:

>100_bases
GCTATTTTTGATTTGGGCTGTAGTTAGAGACCAAAGAAATTAGTTTAAAAATCGACTAATTTCGGTTAAGCTGGAAATAT
AACAAATATATAGGAAGAAA

Downstream 100 bases:

>100_bases
ATACACGTGATTTAGATTATTTTCGGGCGTTAGTTGATTGCCAAAATTATACGATGGTCGCCAAGCAGTTTGCGGTCTCA
CAACCGGCAGTGACTCAAGC

Product: apo-citrate lyase phosphoribosyl-ft dephospho-CoA transferase

Products: NA

Alternate protein names: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Apo-ACP nucleodityltransferase; Holo-ACP synthase; Holo-citrate lyase synthase; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTSMATIFTTGEPQTITAMLAARDQRVAYQQQLTATNPRATIAAIKLNIPGPIKNNAALRRLFLAGVQRFEAELSTYTVA
ADWNHPAGNERFLILTTDFATSKRLAVAFEEHDPLGRLYDIDILQAGSQRALSRTDLGLPKRRCLLCHREAKDCARSRRH
SVAELQQKIAAMYMKEFGERG

Sequences:

>Translated_181_residues
MTSMATIFTTGEPQTITAMLAARDQRVAYQQQLTATNPRATIAAIKLNIPGPIKNNAALRRLFLAGVQRFEAELSTYTVA
ADWNHPAGNERFLILTTDFATSKRLAVAFEEHDPLGRLYDIDILQAGSQRALSRTDLGLPKRRCLLCHREAKDCARSRRH
SVAELQQKIAAMYMKEFGERG
>Mature_180_residues
TSMATIFTTGEPQTITAMLAARDQRVAYQQQLTATNPRATIAAIKLNIPGPIKNNAALRRLFLAGVQRFEAELSTYTVAA
DWNHPAGNERFLILTTDFATSKRLAVAFEEHDPLGRLYDIDILQAGSQRALSRTDLGLPKRRCLLCHREAKDCARSRRHS
VAELQQKIAAMYMKEFGERG

Specific function: Bifunctional enzyme that catalyzes formation of 2-(5''- triphosphoribosyl)-3'-dephosphocoenzyme-A, and then the transfer of this prosthetic group precursor to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield the holo-acyl carrier p

COG id: COG3697

COG function: function code HI; Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786831, Length=167, Percent_Identity=32.3353293413174, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR005551
- InterPro:   IPR017551 [H]

Pfam domain/function: PF01874 CitG; PF03802 CitX [H]

EC number: =2.7.7.61; =2.7.8.25 [H]

Molecular weight: Translated: 20233; Mature: 20101

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMATIFTTGEPQTITAMLAARDQRVAYQQQLTATNPRATIAAIKLNIPGPIKNNAALR
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHH
RLFLAGVQRFEAELSTYTVAADWNHPAGNERFLILTTDFATSKRLAVAFEEHDPLGRLYD
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCEEE
IDILQAGSQRALSRTDLGLPKRRCLLCHREAKDCARSRRHSVAELQQKIAAMYMKEFGER
HHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
G
C
>Mature Secondary Structure 
TSMATIFTTGEPQTITAMLAARDQRVAYQQQLTATNPRATIAAIKLNIPGPIKNNAALR
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHH
RLFLAGVQRFEAELSTYTVAADWNHPAGNERFLILTTDFATSKRLAVAFEEHDPLGRLYD
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCEEE
IDILQAGSQRALSRTDLGLPKRRCLLCHREAKDCARSRRHSVAELQQKIAAMYMKEFGER
HHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10339813 [H]