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The map label for this gene is mleR2 [H]

Identifier: 28377903

GI number: 28377903

Start: 1012997

End: 1013878

Strand: Direct

Name: mleR2 [H]

Synonym: lp_1115

Alternate gene names: 28377903

Gene position: 1012997-1013878 (Clockwise)

Preceding gene: 28377902

Following gene: 28377905

Centisome position: 30.62

GC content: 45.01

Gene sequence:

>882_bases
ATGAATACACGTGATTTAGATTATTTTCGGGCGTTAGTTGATTGCCAAAATTATACGATGGTCGCCAAGCAGTTTGCGGT
CTCACAACCGGCAGTGACTCAAGCAATTCATCGGTTGGAAAAAGAGTTTGCAGTCAAACTGGTGATTCAAGACCGTCGCC
ATCAACAGACAAATATTACCCGGGCCGGTCAGCTGCTTTACAAGAATGCACGCCAGATCCAGGCCAGTTTGCAACTTGCT
CATCGCGAAATTCAGAGTACGTTACAGACTGATATTCGTTTTGGCTTACCACCAATTATTGGCACTTTATATTTCCCTCA
AATTGCGGAAAAGTTACTTCAGAACGGGTTACTGCAACAGTTAAAAATAACGGAAACGGGCTCAGATGAGCTATTGCGTA
AGTTAGTGCATGGTGAGATCAACATCGCGTTATTAGGGTCCTACTTACCATTTGATTTGCCGACAGTTCGTGCGGTTCAC
TTAGGGGCACGGCCATTCAGTATTATCGTGAGTCCTCAAAATAGTTTGGCGAAACAAGCCGCCGTTAGTTTTAAGAATCT
CGGTCAGGCACAGTTCATTGGATTGGATGGCAAATACGTGCACCCACAAGCCTTCCGAGCCTATTGTGACTTTGCCGGGG
TACATCCAGAAGTTATCTACCGGACCCCCGATATCTCATGGGTCAAAGCCTTAGTTAAAGCCAACTTGGGCATTAGCTTA
CTGGTTCGTGATGTGGTTAAAGCGGATGATGGCGTCGTATGTTTGGAGATCAAAGATCAATTGCCGGTCAGCTTCAATAT
CTCGGTGGTCACACGGGCCGGGTACTTACCAACCACTGATGAACAACGGTTTATTGATCAATTACTTAAAATGAAGATTT
AA

Upstream 100 bases:

>100_bases
ACCGTGAAGCCAAGGATTGCGCGCGTTCACGGCGGCATTCAGTGGCTGAGCTACAGCAAAAGATTGCGGCGATGTACATG
AAGGAATTTGGTGAACGCGG

Downstream 100 bases:

>100_bases
ACGTCGCGACTGAGCCATCTGTCTAAGTGAACAGCACGATTCCTTGAGTGGTTCAACTTTTACTTTGAGATTGACGTGTC
TTCACGATTGTTTCATTTGG

Product: malolactic regulator (putative)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNTRDLDYFRALVDCQNYTMVAKQFAVSQPAVTQAIHRLEKEFAVKLVIQDRRHQQTNITRAGQLLYKNARQIQASLQLA
HREIQSTLQTDIRFGLPPIIGTLYFPQIAEKLLQNGLLQQLKITETGSDELLRKLVHGEINIALLGSYLPFDLPTVRAVH
LGARPFSIIVSPQNSLAKQAAVSFKNLGQAQFIGLDGKYVHPQAFRAYCDFAGVHPEVIYRTPDISWVKALVKANLGISL
LVRDVVKADDGVVCLEIKDQLPVSFNISVVTRAGYLPTTDEQRFIDQLLKMKI

Sequences:

>Translated_293_residues
MNTRDLDYFRALVDCQNYTMVAKQFAVSQPAVTQAIHRLEKEFAVKLVIQDRRHQQTNITRAGQLLYKNARQIQASLQLA
HREIQSTLQTDIRFGLPPIIGTLYFPQIAEKLLQNGLLQQLKITETGSDELLRKLVHGEINIALLGSYLPFDLPTVRAVH
LGARPFSIIVSPQNSLAKQAAVSFKNLGQAQFIGLDGKYVHPQAFRAYCDFAGVHPEVIYRTPDISWVKALVKANLGISL
LVRDVVKADDGVVCLEIKDQLPVSFNISVVTRAGYLPTTDEQRFIDQLLKMKI
>Mature_293_residues
MNTRDLDYFRALVDCQNYTMVAKQFAVSQPAVTQAIHRLEKEFAVKLVIQDRRHQQTNITRAGQLLYKNARQIQASLQLA
HREIQSTLQTDIRFGLPPIIGTLYFPQIAEKLLQNGLLQQLKITETGSDELLRKLVHGEINIALLGSYLPFDLPTVRAVH
LGARPFSIIVSPQNSLAKQAAVSFKNLGQAQFIGLDGKYVHPQAFRAYCDFAGVHPEVIYRTPDISWVKALVKANLGISL
LVRDVVKADDGVVCLEIKDQLPVSFNISVVTRAGYLPTTDEQRFIDQLLKMKI

Specific function: Required for malolactic fermentation. It is most probably a transcriptional activator [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=282, Percent_Identity=27.3049645390071, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=264, Percent_Identity=22.3484848484848, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=23.3870967741935, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32919; Mature: 32919

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRDLDYFRALVDCQNYTMVAKQFAVSQPAVTQAIHRLEKEFAVKLVIQDRRHQQTNIT
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RAGQLLYKNARQIQASLQLAHREIQSTLQTDIRFGLPPIIGTLYFPQIAEKLLQNGLLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LKITETGSDELLRKLVHGEINIALLGSYLPFDLPTVRAVHLGARPFSIIVSPQNSLAKQA
EEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHEEEECCCCEEEEECCCHHHHHHH
AVSFKNLGQAQFIGLDGKYVHPQAFRAYCDFAGVHPEVIYRTPDISWVKALVKANLGISL
HHHHHHCCCEEEEECCCCEECHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHH
LVRDVVKADDGVVCLEIKDQLPVSFNISVVTRAGYLPTTDEQRFIDQLLKMKI
HHHHHHCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNTRDLDYFRALVDCQNYTMVAKQFAVSQPAVTQAIHRLEKEFAVKLVIQDRRHQQTNIT
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RAGQLLYKNARQIQASLQLAHREIQSTLQTDIRFGLPPIIGTLYFPQIAEKLLQNGLLQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LKITETGSDELLRKLVHGEINIALLGSYLPFDLPTVRAVHLGARPFSIIVSPQNSLAKQA
EEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHHEEEECCCCEEEEECCCHHHHHHH
AVSFKNLGQAQFIGLDGKYVHPQAFRAYCDFAGVHPEVIYRTPDISWVKALVKANLGISL
HHHHHHCCCEEEEECCCCEECHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHH
LVRDVVKADDGVVCLEIKDQLPVSFNISVVTRAGYLPTTDEQRFIDQLLKMKI
HHHHHHCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2498286; 11337471 [H]