Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 28210290

GI number: 28210290

Start: 571575

End: 572303

Strand: Direct

Name: plsC [H]

Synonym: CTC00551

Alternate gene names: 28210290

Gene position: 571575-572303 (Clockwise)

Preceding gene: 28210287

Following gene: 28210291

Centisome position: 20.42

GC content: 27.98

Gene sequence:

>729_bases
TTGGAGAAGATTAGCATGAATAATTTTTTTCTATATATTCAATTAGGAGCATATATGATAAAAACTGCTTTTAAGAAGAA
AAAAGTTGAAAGAATTAGAAGGATTAAAGGAAATGATGAAGCAGAAAAAATTATAAACGACCATGTATTAAACTGGGCGG
AATACATACTAAAAAAGGCGAAGGTAGAGTTAGAAATTGAAGGTTTAGAGAACTTACCTAAAGAAAGTTGTTTATATGTT
GCTAATCACCAAAGTTTATTTGATATACCAGTTTTATTGGCTGGAATAAGAAAACCTATGGGATTTATTTCAAAGAAAGA
AATTAAAAAAGTTAAGATTATAAGTGAATGGATGGAAATGATACATTGTGTGTTTATAGATAGGGAAAATATAAGAGAAT
CCGTAAAGGCTATAAATAAAGGAATAGATAACTTAAAGCAAGGATATTCTATGGTGATTTTTCCAGAGGGAACAAGAAAT
AAAGAAGGGAAAATAGGTGATTTTAAACAGGGAAGCATGAAACTAGCTTTAAAATCAGGTGTTCCTGTTGTACCAGTAGT
TATTGATGGTACATATAAAATAAGAGAAGGGAATAAAAACAACAAAATAAAACCTGGAAAAGTAAGGCTAATAATAAAGG
AGCCTATATATGTAGATAGATTAGATAAGGAAGATAAAAATAAATTATCAAATATTATAAGGGAAGTAATAAAAAACCAA
TTATCATAA

Upstream 100 bases:

>100_bases
GTATTGTTAATTAAAAATAAATTTAGTCTAATCAGTATAGAATTTTGTTTTTTATATAAAGAGTTATATGTTATAATGTA
ATAGATTAACTAGATAAAGA

Downstream 100 bases:

>100_bases
GCGAAAACTAGGATTATAAGATTACATATCTGGGCCATTAAATGTTTTTAAATAATACTTCAGCTTCTATAAAAATATTG
AGGATGAAGTTTTATTTATT

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MEKISMNNFFLYIQLGAYMIKTAFKKKKVERIRRIKGNDEAEKIINDHVLNWAEYILKKAKVELEIEGLENLPKESCLYV
ANHQSLFDIPVLLAGIRKPMGFISKKEIKKVKIISEWMEMIHCVFIDRENIRESVKAINKGIDNLKQGYSMVIFPEGTRN
KEGKIGDFKQGSMKLALKSGVPVVPVVIDGTYKIREGNKNNKIKPGKVRLIIKEPIYVDRLDKEDKNKLSNIIREVIKNQ
LS

Sequences:

>Translated_242_residues
MEKISMNNFFLYIQLGAYMIKTAFKKKKVERIRRIKGNDEAEKIINDHVLNWAEYILKKAKVELEIEGLENLPKESCLYV
ANHQSLFDIPVLLAGIRKPMGFISKKEIKKVKIISEWMEMIHCVFIDRENIRESVKAINKGIDNLKQGYSMVIFPEGTRN
KEGKIGDFKQGSMKLALKSGVPVVPVVIDGTYKIREGNKNNKIKPGKVRLIIKEPIYVDRLDKEDKNKLSNIIREVIKNQ
LS
>Mature_242_residues
MEKISMNNFFLYIQLGAYMIKTAFKKKKVERIRRIKGNDEAEKIINDHVLNWAEYILKKAKVELEIEGLENLPKESCLYV
ANHQSLFDIPVLLAGIRKPMGFISKKEIKKVKIISEWMEMIHCVFIDRENIRESVKAINKGIDNLKQGYSMVIFPEGTRN
KEGKIGDFKQGSMKLALKSGVPVVPVVIDGTYKIREGNKNNKIKPGKVRLIIKEPIYVDRLDKEDKNKLSNIIREVIKNQ
LS

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=178, Percent_Identity=25.2808988764045, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI15100175, Length=178, Percent_Identity=25.2808988764045, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1789395, Length=168, Percent_Identity=25.5952380952381, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=193, Percent_Identity=25.3886010362694, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=184, Percent_Identity=29.8913043478261, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641614, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24641612, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281364648, Length=185, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582856, Length=185, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582854, Length=185, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27917; Mature: 27917

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKISMNNFFLYIQLGAYMIKTAFKKKKVERIRRIKGNDEAEKIINDHVLNWAEYILKKA
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KVELEIEGLENLPKESCLYVANHQSLFDIPVLLAGIRKPMGFISKKEIKKVKIISEWMEM
HEEEEECCHHCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHCVFIDRENIRESVKAINKGIDNLKQGYSMVIFPEGTRNKEGKIGDFKQGSMKLALKSG
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCC
VPVVPVVIDGTYKIREGNKNNKIKPGKVRLIIKEPIYVDRLDKEDKNKLSNIIREVIKNQ
CCEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHH
LS
CC
>Mature Secondary Structure
MEKISMNNFFLYIQLGAYMIKTAFKKKKVERIRRIKGNDEAEKIINDHVLNWAEYILKKA
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KVELEIEGLENLPKESCLYVANHQSLFDIPVLLAGIRKPMGFISKKEIKKVKIISEWMEM
HEEEEECCHHCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHCVFIDRENIRESVKAINKGIDNLKQGYSMVIFPEGTRNKEGKIGDFKQGSMKLALKSG
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCC
VPVVPVVIDGTYKIREGNKNNKIKPGKVRLIIKEPIYVDRLDKEDKNKLSNIIREVIKNQ
CCEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHH
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]