Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 28210140

GI number: 28210140

Start: 376266

End: 378392

Strand: Direct

Name: rnr [H]

Synonym: CTC00384

Alternate gene names: 28210140

Gene position: 376266-378392 (Clockwise)

Preceding gene: 28210139

Following gene: 28210141

Centisome position: 13.44

GC content: 29.43

Gene sequence:

>2127_bases
ATGAAGATACAAGAAACTCTTATTGAGTTTATGAAAGAACAAGCTTACAAACCCATGAATTTAAAAGAATTAGCTAAAGT
TTTTAATATAAAAGGTGATGAAATAGAAGACTTTAAAAAAGTTTTAGATTATATGGAAAAGGACGGCTTAGTAGTAAAAA
CTAGAACAGAATATTATGGTGTTCCTGAAAGAATGGGATTAATAGTAGGTAAAATTCAAGGTCATCAAAGAGGGTATGCA
TTTTTAATACCAGAAGATGATATACAAGATGTATTTATTCCTGCATCAGGTTTAAATGGTGCAATGAATGGAGATAAGGT
TGTAGTAAAAACTTTTAAAGAGGTGAGGGAAGGTAAAAAATCCGAAGGAGAAGTAATAAGGATATTAAACAGAGCAAATA
AAACCATAATAGGTACCTTTGAAGATAGCAAAAATTTTGGTTTTGTAGTGCCAGATGAGAAGAGAATATATCAAGATATA
TACATACCAAAAGGAAATGTAGCAGGTGCTCATTCAGGCGATATTGTAATTGCTGAAATAACTAAATGGCCCGAAAAAAG
AAGAAGTCCTGAAGGAAAGATAGTGGAGATACTTGGTAAAAAGGGAGAAAAGGGCATAGACATTTTAACTATAATTAAAA
AATATAATTTACCAGAAGAATTTCCTCAAAAAGTCCAAAGTTATTTAGATGGAGTTCCTAATGAAATAAATGAAGAAGAA
TATAAAAATAGGCTAGATTTAAGAGATATAAAGATTATAACTATCGACGGAGAAGATGCAAAAGATTTAGATGATGCCAT
TTCTATTGAAAAATTACCTAATGGAAACTTCTATCTTGGAGTACATATTGCAGATGTATCTCATTATGTTAAAGAAAAGA
ATCCATTAGATAAAGAAGCTTTAAAAAGAGGAACTTCTGTATATCTAGTAGATAGGGTTATACCTATGCTTCCAAAGGAA
TTATCTAATGGTATATGTAGCTTAAATCCTAAAGTTGATAGATTGACTTTAAGTTGTTTTATGGAGATCGATAAAACTGG
TAAAGTAATAGCTCATAAAGTGGCAGAAAGTGTAATAAATTCTTCTGAAAGAATGACTTATACTGATGTGAATAAAATAC
TTAAAGATAATGACCAAGAGCTCATTAAAAAGTATGATTATTTAATGGAAAATTTTAAATCAATGGAAGAACTTTGTAAA
GTACTCTATAAGAAGAGAATAAATAGAGGCGCTATAGATTTTGACTTTGAGGAATGTAAAATAATATTAGATGAAGATGG
AAAACCAGTAGATATTAAACCTTACGAAAGAGAAATAGCAAATAGGATGATAGAGGAATTCATGTTAGTTTGTAATGAAA
CAATAGCGGAGTATATGTTCTGGTCCAATATTCCTTTTGTTTATAGAATACACGAAGAACCAGATCTAGAAAAACTTCAG
CATTTTAATGAATTTGTTTATAATTTAGGATATACAATAAAATACTCTAAAGAAGTTCATCCTAAGTCCTTACAACAAGT
GGTAGAAAAGGTAAGGGGTAAAAAGGAAGAAGTAGTAATAAATACATTATTATTACGTTCTTTAAAGCAGGCAAAATATT
CTCCAGAATGTATAGGACACTTTGGATTAGCAGCAAGATATTATTGTCACTTTACATCACCTATAAGAAGGTATCCAGAT
CTTATAATACACAGAATTATAAAAGAATATATCAAAAATGGTATATCAGAAAAGAGAGTTAAAAAATTAGAAGGGGAAGT
AAGCTCTGCTTCCATACAATCATCAGAAATGGAAAGACTTGCAGAAGAGGCAGAAAGAGAAGTAGATGATTTAAAGAAAG
CTGAATATATGAGTGAAAGAATAGGAGAGGTTTATAATGGAATAATATCTTCAGTAACTGCATTTGGATTATTTGTGGAA
TTGCCTAATACTGTAGAAGGTCTTATACACATAAGCACTCTTTTAGATGATTATTATGTTTACGATGAAAGAGGGTTAAG
ATTAGTAGGAGAAAAAACTAAAAAAATGTATAGATTAGGTGATGAAGTTAAAATAAAAGTTGAAAAAGTAGATTTAGACA
GTTATGAAATTTACTTTGAATTATTAGAAAGTGAAGACAAAAAATAA

Upstream 100 bases:

>100_bases
AAATATTGGAAAAGAAGTAGATAGAAATGAATATTTTTATTAGATAAACTAAAAATAACTATATAAAGAATTAGAAAATA
TAAGTGGGGAGGAAAAAATT

Downstream 100 bases:

>100_bases
AAAATATTATACAGTTTTTTATTTAGTGAATAAGTAATGGTGAATAGCAATGGAAGGAATTCTTTAGTAAAATTTCTTAA
ACCAATGAAAACCCATGTGT

Product: exoribonuclease II

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MKIQETLIEFMKEQAYKPMNLKELAKVFNIKGDEIEDFKKVLDYMEKDGLVVKTRTEYYGVPERMGLIVGKIQGHQRGYA
FLIPEDDIQDVFIPASGLNGAMNGDKVVVKTFKEVREGKKSEGEVIRILNRANKTIIGTFEDSKNFGFVVPDEKRIYQDI
YIPKGNVAGAHSGDIVIAEITKWPEKRRSPEGKIVEILGKKGEKGIDILTIIKKYNLPEEFPQKVQSYLDGVPNEINEEE
YKNRLDLRDIKIITIDGEDAKDLDDAISIEKLPNGNFYLGVHIADVSHYVKEKNPLDKEALKRGTSVYLVDRVIPMLPKE
LSNGICSLNPKVDRLTLSCFMEIDKTGKVIAHKVAESVINSSERMTYTDVNKILKDNDQELIKKYDYLMENFKSMEELCK
VLYKKRINRGAIDFDFEECKIILDEDGKPVDIKPYEREIANRMIEEFMLVCNETIAEYMFWSNIPFVYRIHEEPDLEKLQ
HFNEFVYNLGYTIKYSKEVHPKSLQQVVEKVRGKKEEVVINTLLLRSLKQAKYSPECIGHFGLAARYYCHFTSPIRRYPD
LIIHRIIKEYIKNGISEKRVKKLEGEVSSASIQSSEMERLAEEAEREVDDLKKAEYMSERIGEVYNGIISSVTAFGLFVE
LPNTVEGLIHISTLLDDYYVYDERGLRLVGEKTKKMYRLGDEVKIKVEKVDLDSYEIYFELLESEDKK

Sequences:

>Translated_708_residues
MKIQETLIEFMKEQAYKPMNLKELAKVFNIKGDEIEDFKKVLDYMEKDGLVVKTRTEYYGVPERMGLIVGKIQGHQRGYA
FLIPEDDIQDVFIPASGLNGAMNGDKVVVKTFKEVREGKKSEGEVIRILNRANKTIIGTFEDSKNFGFVVPDEKRIYQDI
YIPKGNVAGAHSGDIVIAEITKWPEKRRSPEGKIVEILGKKGEKGIDILTIIKKYNLPEEFPQKVQSYLDGVPNEINEEE
YKNRLDLRDIKIITIDGEDAKDLDDAISIEKLPNGNFYLGVHIADVSHYVKEKNPLDKEALKRGTSVYLVDRVIPMLPKE
LSNGICSLNPKVDRLTLSCFMEIDKTGKVIAHKVAESVINSSERMTYTDVNKILKDNDQELIKKYDYLMENFKSMEELCK
VLYKKRINRGAIDFDFEECKIILDEDGKPVDIKPYEREIANRMIEEFMLVCNETIAEYMFWSNIPFVYRIHEEPDLEKLQ
HFNEFVYNLGYTIKYSKEVHPKSLQQVVEKVRGKKEEVVINTLLLRSLKQAKYSPECIGHFGLAARYYCHFTSPIRRYPD
LIIHRIIKEYIKNGISEKRVKKLEGEVSSASIQSSEMERLAEEAEREVDDLKKAEYMSERIGEVYNGIISSVTAFGLFVE
LPNTVEGLIHISTLLDDYYVYDERGLRLVGEKTKKMYRLGDEVKIKVEKVDLDSYEIYFELLESEDKK
>Mature_708_residues
MKIQETLIEFMKEQAYKPMNLKELAKVFNIKGDEIEDFKKVLDYMEKDGLVVKTRTEYYGVPERMGLIVGKIQGHQRGYA
FLIPEDDIQDVFIPASGLNGAMNGDKVVVKTFKEVREGKKSEGEVIRILNRANKTIIGTFEDSKNFGFVVPDEKRIYQDI
YIPKGNVAGAHSGDIVIAEITKWPEKRRSPEGKIVEILGKKGEKGIDILTIIKKYNLPEEFPQKVQSYLDGVPNEINEEE
YKNRLDLRDIKIITIDGEDAKDLDDAISIEKLPNGNFYLGVHIADVSHYVKEKNPLDKEALKRGTSVYLVDRVIPMLPKE
LSNGICSLNPKVDRLTLSCFMEIDKTGKVIAHKVAESVINSSERMTYTDVNKILKDNDQELIKKYDYLMENFKSMEELCK
VLYKKRINRGAIDFDFEECKIILDEDGKPVDIKPYEREIANRMIEEFMLVCNETIAEYMFWSNIPFVYRIHEEPDLEKLQ
HFNEFVYNLGYTIKYSKEVHPKSLQQVVEKVRGKKEEVVINTLLLRSLKQAKYSPECIGHFGLAARYYCHFTSPIRRYPD
LIIHRIIKEYIKNGISEKRVKKLEGEVSSASIQSSEMERLAEEAEREVDDLKKAEYMSERIGEVYNGIISSVTAFGLFVE
LPNTVEGLIHISTLLDDYYVYDERGLRLVGEKTKKMYRLGDEVKIKVEKVDLDSYEIYFELLESEDKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=472, Percent_Identity=33.2627118644068, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI190014623, Length=472, Percent_Identity=33.2627118644068, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI134288890, Length=456, Percent_Identity=31.5789473684211, Blast_Score=209, Evalue=1e-53,
Organism=Homo sapiens, GI219521928, Length=574, Percent_Identity=25.0871080139373, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI19115966, Length=574, Percent_Identity=25.0871080139373, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI156105695, Length=497, Percent_Identity=23.1388329979879, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI156105693, Length=495, Percent_Identity=23.030303030303, Blast_Score=93, Evalue=8e-19,
Organism=Escherichia coli, GI87082383, Length=698, Percent_Identity=39.6848137535817, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1787542, Length=643, Percent_Identity=25.8164852255054, Blast_Score=170, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=557, Percent_Identity=28.1867145421903, Blast_Score=186, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17553506, Length=529, Percent_Identity=28.9224952741021, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324552, Length=585, Percent_Identity=29.5726495726496, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320499, Length=422, Percent_Identity=25.8293838862559, Blast_Score=123, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6323943, Length=362, Percent_Identity=25.414364640884, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24649634, Length=473, Percent_Identity=32.9809725158562, Blast_Score=244, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19922976, Length=376, Percent_Identity=33.2446808510638, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24654597, Length=376, Percent_Identity=33.2446808510638, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24654592, Length=376, Percent_Identity=33.2446808510638, Blast_Score=197, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.13.1

Molecular weight: Translated: 81834; Mature: 81834

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIQETLIEFMKEQAYKPMNLKELAKVFNIKGDEIEDFKKVLDYMEKDGLVVKTRTEYYG
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECHHHCC
VPERMGLIVGKIQGHQRGYAFLIPEDDIQDVFIPASGLNGAMNGDKVVVKTFKEVREGKK
CHHHHHHHHEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
SEGEVIRILNRANKTIIGTFEDSKNFGFVVPDEKRIYQDIYIPKGNVAGAHSGDIVIAEI
CCCHHHHHHHHCCCEEEEEEECCCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCEEEEEC
TKWPEKRRSPEGKIVEILGKKGEKGIDILTIIKKYNLPEEFPQKVQSYLDGVPNEINEEE
CCCHHHHCCCCCCEEHEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHH
YKNRLDLRDIKIITIDGEDAKDLDDAISIEKLPNGNFYLGVHIADVSHYVKEKNPLDKEA
HHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCHHH
LKRGTSVYLVDRVIPMLPKELSNGICSLNPKVDRLTLSCFMEIDKTGKVIAHKVAESVIN
HHCCCEEEEHHHHHHHCCHHHCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
SSERMTYTDVNKILKDNDQELIKKYDYLMENFKSMEELCKVLYKKRINRGAIDFDFEECK
CCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCE
IILDEDGKPVDIKPYEREIANRMIEEFMLVCNETIAEYMFWSNIPFVYRIHEEPDLEKLQ
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
HFNEFVYNLGYTIKYSKEVHPKSLQQVVEKVRGKKEEVVINTLLLRSLKQAKYSPECIGH
HHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
FGLAARYYCHFTSPIRRYPDLIIHRIIKEYIKNGISEKRVKKLEGEVSSASIQSSEMERL
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHH
AEEAEREVDDLKKAEYMSERIGEVYNGIISSVTAFGLFVELPNTVEGLIHISTLLDDYYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHE
YDERGLRLVGEKTKKMYRLGDEVKIKVEKVDLDSYEIYFELLESEDKK
ECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIQETLIEFMKEQAYKPMNLKELAKVFNIKGDEIEDFKKVLDYMEKDGLVVKTRTEYYG
CCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECHHHCC
VPERMGLIVGKIQGHQRGYAFLIPEDDIQDVFIPASGLNGAMNGDKVVVKTFKEVREGKK
CHHHHHHHHEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
SEGEVIRILNRANKTIIGTFEDSKNFGFVVPDEKRIYQDIYIPKGNVAGAHSGDIVIAEI
CCCHHHHHHHHCCCEEEEEEECCCCCCEEECCHHHHHHHHCCCCCCCCCCCCCCEEEEEC
TKWPEKRRSPEGKIVEILGKKGEKGIDILTIIKKYNLPEEFPQKVQSYLDGVPNEINEEE
CCCHHHHCCCCCCEEHEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHH
YKNRLDLRDIKIITIDGEDAKDLDDAISIEKLPNGNFYLGVHIADVSHYVKEKNPLDKEA
HHCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCHHH
LKRGTSVYLVDRVIPMLPKELSNGICSLNPKVDRLTLSCFMEIDKTGKVIAHKVAESVIN
HHCCCEEEEHHHHHHHCCHHHCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
SSERMTYTDVNKILKDNDQELIKKYDYLMENFKSMEELCKVLYKKRINRGAIDFDFEECK
CCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCE
IILDEDGKPVDIKPYEREIANRMIEEFMLVCNETIAEYMFWSNIPFVYRIHEEPDLEKLQ
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
HFNEFVYNLGYTIKYSKEVHPKSLQQVVEKVRGKKEEVVINTLLLRSLKQAKYSPECIGH
HHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
FGLAARYYCHFTSPIRRYPDLIIHRIIKEYIKNGISEKRVKKLEGEVSSASIQSSEMERL
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHH
AEEAEREVDDLKKAEYMSERIGEVYNGIISSVTAFGLFVELPNTVEGLIHISTLLDDYYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHE
YDERGLRLVGEKTKKMYRLGDEVKIKVEKVDLDSYEIYFELLESEDKK
ECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]