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The map label for this gene is rsmA [H]

Identifier: 28210013

GI number: 28210013

Start: 216623

End: 217033

Strand: Direct

Name: rsmA [H]

Synonym: CTC00248

Alternate gene names: 28210013

Gene position: 216623-217033 (Clockwise)

Preceding gene: 28210012

Following gene: 28210014

Centisome position: 7.74

GC content: 29.68

Gene sequence:

>411_bases
ATGATACAAAAAGAAGTTGGAGAGAGAATGTCAGCTAAGCCTAAAGCTAAGGAATACGGCTCTTTGTCATTACTAGTTCA
ATATTATTGTGATATAAACATTATAAGAAGAGTTTCACCATCTAGCTTTATACCTAGGCCAAAAGTAGACTCTGTGATAA
TAAAATTAGATAAATTACAAAAACCTAGAGTAAGTGTAAAGGATGAAGAATTATTTTTCAAAATAATAAGGTCTGCTTTT
AATATGAGAAGAAAGACTATGTGGAATGTTATAAAGAGTTTAAGTAATTTAGATAAAGAAATAATAGAAAAGGCTTTTCG
GGTTTCTAACATAGATCCTAAAAGAAGGGGAGAAACTCTATCTGTAGAAGAATTCGCTATCTTATCCGATAGTTTGCATG
AATTAATATAA

Upstream 100 bases:

>100_bases
AAAAAATTTAAAATTAGTTGCCAATCTGCCATACTATGCAACTACTCCCATTATAGCTAAGATATTAAAGCAAGGAGTAA
ATTTTAAATCATTAACAGTA

Downstream 100 bases:

>100_bases
AAATTTTTATTTTTAAGTTCTTGTTCACTTTTTGTATTAATACTCATATATTATAATGAATAAATATATGGGGGTACATC
AATTGGCACAAAAAAAGAAT

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MIQKEVGERMSAKPKAKEYGSLSLLVQYYCDINIIRRVSPSSFIPRPKVDSVIIKLDKLQKPRVSVKDEELFFKIIRSAF
NMRRKTMWNVIKSLSNLDKEIIEKAFRVSNIDPKRRGETLSVEEFAILSDSLHELI

Sequences:

>Translated_136_residues
MIQKEVGERMSAKPKAKEYGSLSLLVQYYCDINIIRRVSPSSFIPRPKVDSVIIKLDKLQKPRVSVKDEELFFKIIRSAF
NMRRKTMWNVIKSLSNLDKEIIEKAFRVSNIDPKRRGETLSVEEFAILSDSLHELI
>Mature_136_residues
MIQKEVGERMSAKPKAKEYGSLSLLVQYYCDINIIRRVSPSSFIPRPKVDSVIIKLDKLQKPRVSVKDEELFFKIIRSAF
NMRRKTMWNVIKSLSNLDKEIIEKAFRVSNIDPKRRGETLSVEEFAILSDSLHELI

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Homo sapiens, GI156415992, Length=131, Percent_Identity=29.0076335877863, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786236, Length=135, Percent_Identity=40, Blast_Score=96, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 15828; Mature: 15828

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKEVGERMSAKPKAKEYGSLSLLVQYYCDINIIRRVSPSSFIPRPKVDSVIIKLDKLQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
KPRVSVKDEELFFKIIRSAFNMRRKTMWNVIKSLSNLDKEIIEKAFRVSNIDPKRRGETL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
SVEEFAILSDSLHELI
CHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIQKEVGERMSAKPKAKEYGSLSLLVQYYCDINIIRRVSPSSFIPRPKVDSVIIKLDKLQ
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
KPRVSVKDEELFFKIIRSAFNMRRKTMWNVIKSLSNLDKEIIEKAFRVSNIDPKRRGETL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
SVEEFAILSDSLHELI
CHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA