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The map label for this gene is glcK [H]

Identifier: 28209997

GI number: 28209997

Start: 197483

End: 198436

Strand: Direct

Name: glcK [H]

Synonym: CTC00230

Alternate gene names: 28209997

Gene position: 197483-198436 (Clockwise)

Preceding gene: 161486852

Following gene: 28209998

Centisome position: 7.05

GC content: 30.19

Gene sequence:

>954_bases
GTGAATAAAAAGTATGTAGTAGGAATAGACTTAGGTGGTACAACTATAAGCGGAGGAGTATTAGATTATGAAGGAAATAT
AGTTTTTAGACATACTATAGATACTAAGTCTGAACTTGGAGAGAAAATTGTACTAGAAAGAATCATAAAAGTTATAGATT
ATGTAATAAAAAAATCAAAGATTCCTAAGAATAATATAAAAGCAATAGGAATTGGATCACCAGGACCTTTAGATATAGAA
AAAGGAATTATTATAACTAGTCCCAATTTACCATTTAAAAATTTTAATATAGTTAATCCAATAAAAAATCATTTTAAAAT
CTCTGTTTATTTAGATAATGATGCCAATGCGGCAGCAGTAGGAGAGTATAAATTTGGATCTGGAAAAGGAAGCAGAAACA
TGATATTTATAACTGTTTCTACAGGAATAGGTGGAGGAGCAATATTAAATGGGAACATATATAGAGGTAGTAGTTCCAAT
GCTTTAGAAATAGGGCATATGACTTTAAAAGAAGATGGAGCCATATGTAATTGTGGAAATTTTGGATGTGCAGAAGCATT
GGCATCGGGCACAGCTATAGCTAAAAAAGCAAGAATGGAATTGAATAGAGGAAAAGAAAGCTCATTGAAAAAACTAAAGA
AGATTTCAGCATATAATGTTTTTCAAGAAGCTAAAAATGGAGATAAATTAGCACAAGAAATTGTAGACGAGGCTTTGGAG
TATTTAGGTATATGTGTTTCAAACATAATTATAACCTTTGATCCAGATACTATAGTTATAGGTGGAGGGGTATCAAAAGC
TGGAGATATAATATTTAATAAAATAAACCAAGTTGTAAAAGAAAGGTGCTTTGAAGCTATGTGGAAAAATACTAAAATAA
TAAAAGCTTTGTTATTAGAGGATGCAGGTATTATTGGGGCAGCTTCATTAGCTATATTTGAAGAAAGTAAATAA

Upstream 100 bases:

>100_bases
TAGCATTAAAATATACAATTTATTTTAAATATGTTTGAATTATTGACAAAAAATTAGTGAATGATAGTATTTAATTATAA
TATGTTTAGGAGGGGGTCTA

Downstream 100 bases:

>100_bases
ATTTATATAATAATTTTACAAATTCTTTTAAGAATTTTCTTAACATTTGGGATATTTCATGATATTATATTAATATAGAC
AAAACATAAAATATTTTAGA

Product: transcriptional repressor

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNKKYVVGIDLGGTTISGGVLDYEGNIVFRHTIDTKSELGEKIVLERIIKVIDYVIKKSKIPKNNIKAIGIGSPGPLDIE
KGIIITSPNLPFKNFNIVNPIKNHFKISVYLDNDANAAAVGEYKFGSGKGSRNMIFITVSTGIGGGAILNGNIYRGSSSN
ALEIGHMTLKEDGAICNCGNFGCAEALASGTAIAKKARMELNRGKESSLKKLKKISAYNVFQEAKNGDKLAQEIVDEALE
YLGICVSNIIITFDPDTIVIGGGVSKAGDIIFNKINQVVKERCFEAMWKNTKIIKALLLEDAGIIGAASLAIFEESK

Sequences:

>Translated_317_residues
MNKKYVVGIDLGGTTISGGVLDYEGNIVFRHTIDTKSELGEKIVLERIIKVIDYVIKKSKIPKNNIKAIGIGSPGPLDIE
KGIIITSPNLPFKNFNIVNPIKNHFKISVYLDNDANAAAVGEYKFGSGKGSRNMIFITVSTGIGGGAILNGNIYRGSSSN
ALEIGHMTLKEDGAICNCGNFGCAEALASGTAIAKKARMELNRGKESSLKKLKKISAYNVFQEAKNGDKLAQEIVDEALE
YLGICVSNIIITFDPDTIVIGGGVSKAGDIIFNKINQVVKERCFEAMWKNTKIIKALLLEDAGIIGAASLAIFEESK
>Mature_317_residues
MNKKYVVGIDLGGTTISGGVLDYEGNIVFRHTIDTKSELGEKIVLERIIKVIDYVIKKSKIPKNNIKAIGIGSPGPLDIE
KGIIITSPNLPFKNFNIVNPIKNHFKISVYLDNDANAAAVGEYKFGSGKGSRNMIFITVSTGIGGGAILNGNIYRGSSSN
ALEIGHMTLKEDGAICNCGNFGCAEALASGTAIAKKARMELNRGKESSLKKLKKISAYNVFQEAKNGDKLAQEIVDEALE
YLGICVSNIIITFDPDTIVIGGGVSKAGDIIFNKINQVVKERCFEAMWKNTKIIKALLLEDAGIIGAASLAIFEESK

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=265, Percent_Identity=32.4528301886792, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI298566315, Length=265, Percent_Identity=32.4528301886792, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI4885285, Length=265, Percent_Identity=32.4528301886792, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI190014632, Length=265, Percent_Identity=32.4528301886792, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI298566312, Length=114, Percent_Identity=35.9649122807018, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787878, Length=271, Percent_Identity=28.7822878228782, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786891, Length=309, Percent_Identity=26.537216828479, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87081733, Length=313, Percent_Identity=25.5591054313099, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082127, Length=229, Percent_Identity=25.3275109170306, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787363, Length=316, Percent_Identity=26.2658227848101, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082230, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790522, Length=272, Percent_Identity=24.6323529411765, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34047; Mature: 34047

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKYVVGIDLGGTTISGGVLDYEGNIVFRHTIDTKSELGEKIVLERIIKVIDYVIKKSK
CCCCEEEEEECCCCEEECCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
IPKNNIKAIGIGSPGPLDIEKGIIITSPNLPFKNFNIVNPIKNHFKISVYLDNDANAAAV
CCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCCEEEEEEECCCCCEEEE
GEYKFGSGKGSRNMIFITVSTGIGGGAILNGNIYRGSSSNALEIGHMTLKEDGAICNCGN
ECEECCCCCCCCEEEEEEEECCCCCCEEEECEEEECCCCCEEEEEEEEEECCCCEEECCC
FGCAEALASGTAIAKKARMELNRGKESSLKKLKKISAYNVFQEAKNGDKLAQEIVDEALE
CCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
YLGICVSNIIITFDPDTIVIGGGVSKAGDIIFNKINQVVKERCFEAMWKNTKIIKALLLE
HHHHHHHCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DAGIIGAASLAIFEESK
CCCCEEEEEEEEEECCC
>Mature Secondary Structure
MNKKYVVGIDLGGTTISGGVLDYEGNIVFRHTIDTKSELGEKIVLERIIKVIDYVIKKSK
CCCCEEEEEECCCCEEECCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
IPKNNIKAIGIGSPGPLDIEKGIIITSPNLPFKNFNIVNPIKNHFKISVYLDNDANAAAV
CCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCEECCCCCCCEEEEEEECCCCCEEEE
GEYKFGSGKGSRNMIFITVSTGIGGGAILNGNIYRGSSSNALEIGHMTLKEDGAICNCGN
ECEECCCCCCCCEEEEEEEECCCCCCEEEECEEEECCCCCEEEEEEEEEECCCCEEECCC
FGCAEALASGTAIAKKARMELNRGKESSLKKLKKISAYNVFQEAKNGDKLAQEIVDEALE
CCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
YLGICVSNIIITFDPDTIVIGGGVSKAGDIIFNKINQVVKERCFEAMWKNTKIIKALLLE
HHHHHHHCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DAGIIGAASLAIFEESK
CCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]