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The map label for this gene is tal

Identifier: 161486852

GI number: 161486852

Start: 195206

End: 195850

Strand: Direct

Name: tal

Synonym: CTC00228

Alternate gene names: 161486852

Gene position: 195206-195850 (Clockwise)

Preceding gene: 28209994

Following gene: 28209997

Centisome position: 6.97

GC content: 31.01

Gene sequence:

>645_bases
ATGAAATTTTTTATAGACACAGCTAATGTAGAAGAAATAAAAAAAGTAGCTAAATGGGGAGTTTTAGATGGGGTCACAAC
TAATCCAACCTTAATAGCAAGAGAAGGCAGAGACCTTAAAGAAGTTATTGAAGAAATATGTTCAATTGTAGATGGACCTA
TAAGTGCAGAGGTTATTAGTTTAGAATCAGAAAAAATGGTAGAAGAAGCTAAAGAACTTATAAAAATACACAAAAATATA
GTAATAAAAGTGCCTATGTGTGAAGAAGGATTAAAAGCAGTTAGTGAATTAACTAAATTAGGTATAAAAACTAATGTTAC
ACTAATCTTTTCAGCGCAACAAGCATTATTGGCAGCAAAAGCCGGAGCCACATATGTTAGTCCTTTTTTAGGTAGAATAG
ATGACATAGGAAGTTTTGGTATCCAATTAGTAGAAGATATAGTTACTATATTCACTAACTTTGGTATAGAATCAGAGATA
ATATGTGCTAGTATAAGAACTCCAATTCATGTATTAGAATGTGCTAGAGTAGGTGGAGACATTGCAACTGTACCTTATAA
AGTATTTGCTCAAATGTTAAAGCATCCTCTAACAGATAGAGGTATAGAACAATTTTTAGAAGATTATAAAAGCATGAACA
AATAA

Upstream 100 bases:

>100_bases
TTATATTGAAAAGTCAACATAATTTAAATTAATTAAATTTTAAATACTCTGATGAGATGGTATAATGGTTATAATAGATT
TATTGAAAGGAGTAGTTTAT

Downstream 100 bases:

>100_bases
TATAAGCTTTAAAATGATTTTAAAAATAAACATAAAATTGAAAGAAAAATTATGTATTTTGTCTTAATAATCCACAATAT
GTTAAAGCACTTATCAACAT

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKFFIDTANVEEIKKVAKWGVLDGVTTNPTLIAREGRDLKEVIEEICSIVDGPISAEVISLESEKMVEEAKELIKIHKNI
VIKVPMCEEGLKAVSELTKLGIKTNVTLIFSAQQALLAAKAGATYVSPFLGRIDDIGSFGIQLVEDIVTIFTNFGIESEI
ICASIRTPIHVLECARVGGDIATVPYKVFAQMLKHPLTDRGIEQFLEDYKSMNK

Sequences:

>Translated_214_residues
MKFFIDTANVEEIKKVAKWGVLDGVTTNPTLIAREGRDLKEVIEEICSIVDGPISAEVISLESEKMVEEAKELIKIHKNI
VIKVPMCEEGLKAVSELTKLGIKTNVTLIFSAQQALLAAKAGATYVSPFLGRIDDIGSFGIQLVEDIVTIFTNFGIESEI
ICASIRTPIHVLECARVGGDIATVPYKVFAQMLKHPLTDRGIEQFLEDYKSMNK
>Mature_214_residues
MKFFIDTANVEEIKKVAKWGVLDGVTTNPTLIAREGRDLKEVIEEICSIVDGPISAEVISLESEKMVEEAKELIKIHKNI
VIKVPMCEEGLKAVSELTKLGIKTNVTLIFSAQQALLAAKAGATYVSPFLGRIDDIGSFGIQLVEDIVTIFTNFGIESEI
ICASIRTPIHVLECARVGGDIATVPYKVFAQMLKHPLTDRGIEQFLEDYKSMNK

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=174, Percent_Identity=31.6091954022989, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI87081788, Length=212, Percent_Identity=35.377358490566, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790382, Length=213, Percent_Identity=38.4976525821596, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788807, Length=189, Percent_Identity=31.2169312169312, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI1786189, Length=154, Percent_Identity=33.7662337662338, Blast_Score=73, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321480, Length=212, Percent_Identity=29.2452830188679, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323386, Length=129, Percent_Identity=36.4341085271318, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45549185, Length=146, Percent_Identity=34.2465753424658, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_CLOTE (Q899F3)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_780939.2
- ProteinModelPortal:   Q899F3
- SMR:   Q899F3
- GeneID:   1059604
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC00228
- NMPDR:   fig|212717.1.peg.161
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- PhylomeDB:   Q899F3
- ProtClustDB:   PRK01362
- BioCyc:   CTET212717:CTC_00228-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23568; Mature: 23568

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFIDTANVEEIKKVAKWGVLDGVTTNPTLIAREGRDLKEVIEEICSIVDGPISAEVIS
CEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHH
LESEKMVEEAKELIKIHKNIVIKVPMCEEGLKAVSELTKLGIKTNVTLIFSAQQALLAAK
CHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
AGATYVSPFLGRIDDIGSFGIQLVEDIVTIFTNFGIESEIICASIRTPIHVLECARVGGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCC
IATVPYKVFAQMLKHPLTDRGIEQFLEDYKSMNK
HHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFFIDTANVEEIKKVAKWGVLDGVTTNPTLIAREGRDLKEVIEEICSIVDGPISAEVIS
CEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHH
LESEKMVEEAKELIKIHKNIVIKVPMCEEGLKAVSELTKLGIKTNVTLIFSAQQALLAAK
CHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHH
AGATYVSPFLGRIDDIGSFGIQLVEDIVTIFTNFGIESEIICASIRTPIHVLECARVGGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCC
IATVPYKVFAQMLKHPLTDRGIEQFLEDYKSMNK
HHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129