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The map label for this gene is accD [H]

Identifier: 62184968

GI number: 62184968

Start: 391148

End: 392074

Strand: Direct

Name: accD [H]

Synonym: CAB338

Alternate gene names: 62184968

Gene position: 391148-392074 (Clockwise)

Preceding gene: 62184967

Following gene: 62184969

Centisome position: 34.18

GC content: 42.29

Gene sequence:

>927_bases
GTGCGTTTATTTTCTTACGATAAACCTAAGATTAAAGTGCAAAAGATAAAAGCTGATGGTTTTAGCGGGTGGTTAAAATG
CACGCATTGCCATGAAATGATTCATGCAAATGAATTAGGACAAAATTTTAATTGTTGTCCTAAGTGCTCTTACCACTATC
GTATTACCGCAACTGAGCGCATCAAATTGCTCACGGATAAAGATTCTTGGCGTCCTTTGTACGCAAATCTCAAATCACAA
GATCCTCTAAAGTTTGTCGATACCGACACCTACACAAATCGTTTGGCTAAGGCTAGAAAAGATAACACAGAAAGCGAAGG
CGTTCTTGTGGGTATTTGTACCATAGGGGAGCATCCTGTGGCCTTGGCCGTGATGGATTTTAATTTTATGGCAGGCTCTA
TGGGCGCTGTTGTCGGTGAAAAATTGACGCGCTTGATAGAAAAAGCGATAGAATCCAAGCTCCCCGTCGTTATTGTATGT
GCTTCCGGAGGCGCTCGGATGCAAGAATCCGTCTTCTCCTTAATGCAAATGGCAAAAACATCCGCAGCATTAGCCAAGTT
GCACGAAGCGGGTCTACCCTATATTTCCGTGTTGACTAATCCTACATCCGGAGGGGTGACAGCTTCTTTTGCCTCTTTAG
GTGATGTCATTATTGCAGAACCTAAAGCTCTTATTTGCTTTGCCGGTCCTCGTGTTGTCGCTCAAGTGATTGGTGAAGAT
CTTCCCGAAGGTGCTCAAAAGTCTGAATTTCTCCTCGAACACGGAATGATTGATAAAGTGGTAGAGAGAAAACAATTAAA
GAGCACGTTGCAGAGTTTACTTGATTACTTTTGTTCTCAAGAATACACTGGCGGCCAGGATAAAGCCCCTAGGGATTTAT
CCAAGACAATTAAAGAAATTTTTTTGTTGACAGATGACAGTGAATAA

Upstream 100 bases:

>100_bases
AGATAACTAAAGATAACTAATTAAAAGAGTATTTTTAATTGAAGAGTTAATAACTTTAATTTAAAATTACTTAAGCTAAA
AAAATTGGATTAGGTAGCTT

Downstream 100 bases:

>100_bases
AACATCATACCCGCTACTCGTAGTAACCACGGCGCTGTTCCTATGACTATATTATGTGAATTAGAATCTGGAGTATCTCT
TCCAGAATATGCTACCGAAG

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRLFSYDKPKIKVQKIKADGFSGWLKCTHCHEMIHANELGQNFNCCPKCSYHYRITATERIKLLTDKDSWRPLYANLKSQ
DPLKFVDTDTYTNRLAKARKDNTESEGVLVGICTIGEHPVALAVMDFNFMAGSMGAVVGEKLTRLIEKAIESKLPVVIVC
ASGGARMQESVFSLMQMAKTSAALAKLHEAGLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVAQVIGED
LPEGAQKSEFLLEHGMIDKVVERKQLKSTLQSLLDYFCSQEYTGGQDKAPRDLSKTIKEIFLLTDDSE

Sequences:

>Translated_308_residues
MRLFSYDKPKIKVQKIKADGFSGWLKCTHCHEMIHANELGQNFNCCPKCSYHYRITATERIKLLTDKDSWRPLYANLKSQ
DPLKFVDTDTYTNRLAKARKDNTESEGVLVGICTIGEHPVALAVMDFNFMAGSMGAVVGEKLTRLIEKAIESKLPVVIVC
ASGGARMQESVFSLMQMAKTSAALAKLHEAGLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVAQVIGED
LPEGAQKSEFLLEHGMIDKVVERKQLKSTLQSLLDYFCSQEYTGGQDKAPRDLSKTIKEIFLLTDDSE
>Mature_308_residues
MRLFSYDKPKIKVQKIKADGFSGWLKCTHCHEMIHANELGQNFNCCPKCSYHYRITATERIKLLTDKDSWRPLYANLKSQ
DPLKFVDTDTYTNRLAKARKDNTESEGVLVGICTIGEHPVALAVMDFNFMAGSMGAVVGEKLTRLIEKAIESKLPVVIVC
ASGGARMQESVFSLMQMAKTSAALAKLHEAGLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVAQVIGED
LPEGAQKSEFLLEHGMIDKVVERKQLKSTLQSLLDYFCSQEYTGGQDKAPRDLSKTIKEIFLLTDDSE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=246, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788655, Length=269, Percent_Identity=49.814126394052, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 33918; Mature: 33918

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFSYDKPKIKVQKIKADGFSGWLKCTHCHEMIHANELGQNFNCCPKCSYHYRITATER
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCE
IKLLTDKDSWRPLYANLKSQDPLKFVDTDTYTNRLAKARKDNTESEGVLVGICTIGEHPV
EEEEECCCCCCHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCE
ALAVMDFNFMAGSMGAVVGEKLTRLIEKAIESKLPVVIVCASGGARMQESVFSLMQMAKT
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLHEAGLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVAQVIGED
HHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCEEEECCCEEEEECCHHHHHHHHHCC
LPEGAQKSEFLLEHGMIDKVVERKQLKSTLQSLLDYFCSQEYTGGQDKAPRDLSKTIKEI
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
FLLTDDSE
EEECCCCC
>Mature Secondary Structure
MRLFSYDKPKIKVQKIKADGFSGWLKCTHCHEMIHANELGQNFNCCPKCSYHYRITATER
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCE
IKLLTDKDSWRPLYANLKSQDPLKFVDTDTYTNRLAKARKDNTESEGVLVGICTIGEHPV
EEEEECCCCCCHHHHCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCE
ALAVMDFNFMAGSMGAVVGEKLTRLIEKAIESKLPVVIVCASGGARMQESVFSLMQMAKT
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLHEAGLPYISVLTNPTSGGVTASFASLGDVIIAEPKALICFAGPRVVAQVIGED
HHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHHCCEEEECCCEEEEECCHHHHHHHHHCC
LPEGAQKSEFLLEHGMIDKVVERKQLKSTLQSLLDYFCSQEYTGGQDKAPRDLSKTIKEI
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
FLLTDDSE
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA