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The map label for this gene is dgoT [H]

Identifier: 28572808

GI number: 28572808

Start: 758459

End: 759691

Strand: Reverse

Name: dgoT [H]

Synonym: TW667

Alternate gene names: 28572808

Gene position: 759691-758459 (Counterclockwise)

Preceding gene: 28572809

Following gene: 28572805

Centisome position: 82.05

GC content: 48.01

Gene sequence:

>1233_bases
GTGTCTGTTGCGGTTGATGAAATCAAAGCCGAATTTAATATGAACGATATTCAGATGGGCTTTCTTCTGTCTCAATTCGT
TTGGGGGATCGTGATAGTCATTCCTCTCATTGCCTATTTGCTCCAGAGGTTTGGCGCGCGTTCCGTCGGCGGGTACGGCG
TGTTGGGATTCTCGCTTATGACGCTTTTCACGCCATTTTCGACAGGGTTTTATAGCTTCGCGTTTTTCCGCCTTGGTCTC
GGTGCTTTTGAAGCACCAACATTCCCCGTGAATTCATTTTTTGCAAGAAAATGGTTTCCGCGGCGCGATCGCGCAAAAGC
TGTTAGTGCCTATATGGCAGCCTCTTTTGCCGGCCTTGCCTTTGCCGTTCCGGTTCTTACGTGGATACTCGGCGTGTTTG
CTACATGGCGCGCTGTGTTTGTGTTTGGCGGTATTGTCGGTATTGTTGTGTCAATTATCTGGTTTCTGTCGATTCGCTCC
GATGATCCATCCAAGTCTCGTTTTGTTTCTAAGGAAGAGCTTGAGTATATACAGAGTGATTCTCCTGACGCAAAGGACAA
TAAGGTAAAGGCGCGCGCCAGCTTTAGAGATTGGGTTGCCGTCCTGACACACCGCAGGCTTGTCGGACTTTATATAGGTG
CGTTTTCTACATCGACAATTGTTTTCTTCTTTATAAGTTGGTTTCCAAATTACCTGAAGAGCAATCTTGGCTTTGATCTT
AAGAGTGGAGCGTTATACCTTTCTTCAGCACCGTACATCGCCGGGATATTTGGTATGTTGTTCGCTGGATGGTTGTCCGA
TCGCCTAGTAAAGGCCGGTTTTACCCCGGGAAATGCCCGTAAGGTAACTGTAACTGTCGGCCTGACCGGATCAATTCCCC
TTCTCTTTATTCCTATTATGGGTGGTGCCCCGCGGTGGGTCCTTTTCTCTCTGGTGATTGTTGTTTTCTTTTTCGCGGGT
ATGGCAAATACCGCCTGGCTTCTGGCTTCAGAGATTGCAACTCCGCGGCTTCTCGGCCTTACAACCGGTGTTTACGGGTT
CTGGGTTAATCTGTTTGGTGCCTCATCTCCGCTGGTTGTTGGGTTTATACTGCAGTTCACCGGGCACAACTATGGTGCCG
TCTTCACATATCTCGGTATTGCTGCACTTATTGGTGTTATAGCCTATGTGTTTGTGATAGACAAGGTTGAGTCAATTCCT
GATCGCGTAAAGACAAAGACAAATCCTGCCTGA

Upstream 100 bases:

>100_bases
ACTTGGGGGTTCTATGGCACGCCGGGCTACGTGTTATCGATACTGGGTTCTTATAGTTCTGTCATTGGTAACGTTTACAA
ACTATCTTGATAGAGCAACG

Downstream 100 bases:

>100_bases
CGGGTGTGTCTTTAGCGCAATTTGCTTACTGCCGTTAGGCTTCGGATTCCTTGAGCGAGGCGTCTTCTGGATTTGTGGTG
TCACCGTAGTTAAGCCTTTT

Product: integral membrane sugar transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSVAVDEIKAEFNMNDIQMGFLLSQFVWGIVIVIPLIAYLLQRFGARSVGGYGVLGFSLMTLFTPFSTGFYSFAFFRLGL
GAFEAPTFPVNSFFARKWFPRRDRAKAVSAYMAASFAGLAFAVPVLTWILGVFATWRAVFVFGGIVGIVVSIIWFLSIRS
DDPSKSRFVSKEELEYIQSDSPDAKDNKVKARASFRDWVAVLTHRRLVGLYIGAFSTSTIVFFFISWFPNYLKSNLGFDL
KSGALYLSSAPYIAGIFGMLFAGWLSDRLVKAGFTPGNARKVTVTVGLTGSIPLLFIPIMGGAPRWVLFSLVIVVFFFAG
MANTAWLLASEIATPRLLGLTTGVYGFWVNLFGASSPLVVGFILQFTGHNYGAVFTYLGIAALIGVIAYVFVIDKVESIP
DRVKTKTNPA

Sequences:

>Translated_410_residues
MSVAVDEIKAEFNMNDIQMGFLLSQFVWGIVIVIPLIAYLLQRFGARSVGGYGVLGFSLMTLFTPFSTGFYSFAFFRLGL
GAFEAPTFPVNSFFARKWFPRRDRAKAVSAYMAASFAGLAFAVPVLTWILGVFATWRAVFVFGGIVGIVVSIIWFLSIRS
DDPSKSRFVSKEELEYIQSDSPDAKDNKVKARASFRDWVAVLTHRRLVGLYIGAFSTSTIVFFFISWFPNYLKSNLGFDL
KSGALYLSSAPYIAGIFGMLFAGWLSDRLVKAGFTPGNARKVTVTVGLTGSIPLLFIPIMGGAPRWVLFSLVIVVFFFAG
MANTAWLLASEIATPRLLGLTTGVYGFWVNLFGASSPLVVGFILQFTGHNYGAVFTYLGIAALIGVIAYVFVIDKVESIP
DRVKTKTNPA
>Mature_409_residues
SVAVDEIKAEFNMNDIQMGFLLSQFVWGIVIVIPLIAYLLQRFGARSVGGYGVLGFSLMTLFTPFSTGFYSFAFFRLGLG
AFEAPTFPVNSFFARKWFPRRDRAKAVSAYMAASFAGLAFAVPVLTWILGVFATWRAVFVFGGIVGIVVSIIWFLSIRSD
DPSKSRFVSKEELEYIQSDSPDAKDNKVKARASFRDWVAVLTHRRLVGLYIGAFSTSTIVFFFISWFPNYLKSNLGFDLK
SGALYLSSAPYIAGIFGMLFAGWLSDRLVKAGFTPGNARKVTVTVGLTGSIPLLFIPIMGGAPRWVLFSLVIVVFFFAGM
ANTAWLLASEIATPRLLGLTTGVYGFWVNLFGASSPLVVGFILQFTGHNYGAVFTYLGIAALIGVIAYVFVIDKVESIPD
RVKTKTNPA

Specific function: Intake of galactonate into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=300, Percent_Identity=27, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI9966811, Length=356, Percent_Identity=23.5955056179775, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI9945322, Length=386, Percent_Identity=22.5388601036269, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI21322234, Length=383, Percent_Identity=22.7154046997389, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI5031955, Length=278, Percent_Identity=24.8201438848921, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI148743791, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=35.609756097561, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789152, Length=415, Percent_Identity=29.8795180722892, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789515, Length=412, Percent_Identity=27.9126213592233, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI2367379, Length=404, Percent_Identity=26.4851485148515, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI2367193, Length=421, Percent_Identity=20.6650831353919, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082071, Length=326, Percent_Identity=24.2331288343558, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788573, Length=354, Percent_Identity=23.4463276836158, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=323, Percent_Identity=25.3869969040248, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193205400, Length=280, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=361, Percent_Identity=23.2686980609418, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533554, Length=361, Percent_Identity=23.2686980609418, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560030, Length=332, Percent_Identity=22.8915662650602, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32565916, Length=278, Percent_Identity=24.8201438848921, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=242, Percent_Identity=25.6198347107438, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71997452, Length=391, Percent_Identity=21.9948849104859, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32566049, Length=321, Percent_Identity=24.2990654205607, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=382, Percent_Identity=21.7277486910995, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=382, Percent_Identity=21.7277486910995, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=372, Percent_Identity=21.505376344086, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=258, Percent_Identity=21.7054263565891, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535049, Length=410, Percent_Identity=20.9756097560976, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648416, Length=394, Percent_Identity=27.4111675126904, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21356189, Length=394, Percent_Identity=27.4111675126904, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24655255, Length=413, Percent_Identity=25.90799031477, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI45550460, Length=413, Percent_Identity=25.90799031477, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28573708, Length=363, Percent_Identity=24.7933884297521, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573707, Length=363, Percent_Identity=24.7933884297521, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654215, Length=366, Percent_Identity=25.4098360655738, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20130167, Length=370, Percent_Identity=26.7567567567568, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922400, Length=367, Percent_Identity=25.3405994550409, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641682, Length=384, Percent_Identity=25.5208333333333, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20130135, Length=372, Percent_Identity=24.7311827956989, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24658658, Length=399, Percent_Identity=22.5563909774436, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24655271, Length=372, Percent_Identity=24.7311827956989, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI20129235, Length=287, Percent_Identity=27.1777003484321, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550364, Length=262, Percent_Identity=27.0992366412214, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639764, Length=375, Percent_Identity=24, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550495, Length=257, Percent_Identity=24.9027237354086, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583789, Length=303, Percent_Identity=24.7524752475248, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24658689, Length=251, Percent_Identity=23.9043824701195, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45552797, Length=251, Percent_Identity=23.9043824701195, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573299, Length=350, Percent_Identity=23.7142857142857, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658674, Length=251, Percent_Identity=23.5059760956175, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580790, Length=279, Percent_Identity=26.5232974910394, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584153, Length=372, Percent_Identity=22.5806451612903, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24658666, Length=251, Percent_Identity=23.5059760956175, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62484226, Length=263, Percent_Identity=22.8136882129278, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651789, Length=373, Percent_Identity=23.0563002680965, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24651787, Length=373, Percent_Identity=23.0563002680965, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45028; Mature: 44897

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00018 EF_HAND_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVAVDEIKAEFNMNDIQMGFLLSQFVWGIVIVIPLIAYLLQRFGARSVGGYGVLGFSLM
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
TLFTPFSTGFYSFAFFRLGLGAFEAPTFPVNSFFARKWFPRRDRAKAVSAYMAASFAGLA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
FAVPVLTWILGVFATWRAVFVFGGIVGIVVSIIWFLSIRSDDPSKSRFVSKEELEYIQSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCC
SPDAKDNKVKARASFRDWVAVLTHRRLVGLYIGAFSTSTIVFFFISWFPNYLKSNLGFDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
KSGALYLSSAPYIAGIFGMLFAGWLSDRLVKAGFTPGNARKVTVTVGLTGSIPLLFIPIM
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEECC
GGAPRWVLFSLVIVVFFFAGMANTAWLLASEIATPRLLGLTTGVYGFWVNLFGASSPLVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHH
GFILQFTGHNYGAVFTYLGIAALIGVIAYVFVIDKVESIPDRVKTKTNPA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]