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The map label for this gene is iolC [H]

Identifier: 28572809

GI number: 28572809

Start: 760086

End: 761030

Strand: Reverse

Name: iolC [H]

Synonym: TW668

Alternate gene names: 28572809

Gene position: 761030-760086 (Counterclockwise)

Preceding gene: 28572810

Following gene: 28572808

Centisome position: 82.19

GC content: 52.28

Gene sequence:

>945_bases
GTGCCTAGATACGATGTTGTTTCTTTGGGCGAGGGTCAGATACGTCTCACCGTTCCACGTGGAGAGAATCTTCTTACGGC
AAAGCAGCTTTACTTGACTGCAGCCGGTTCGGAGGCAAATGTAACAGGGCTTCTGTCTCAGCTGGGTCATTCTTGTGCGT
GGGCATCTGTAATACCGAAAGGTGAGCTTGGTGATCGCATAGTCAGAGAGTACAGAGCCGTTGGTACGGATGTGTCTCAT
ATCGTACGGACGGACACGGGACGCGTGGCTCTTTATTTCTTACAGCCAGGCGCGGACCCAATGCCCGCCGAGGTTGTGTA
TGACAGGCTACACACGCCGTTTAGGGAGATAGAACCCGAGATATTTGATTGGGGATCCTTACTTGATACGCGCATTCTTT
TTATAACTGGCATAACCATGGCTTTAACAGAAAAAACAAGACGGGTGATTGAGTATGGTGTTGCCTGCGCGTCAGAACGG
GGTGTCGATATTGTCCTCGATGTGAATCACAGGGCCCGTCTCTGGAGTGGCAAGGAGGCAAGAGGTGTCATCGTTCCGCT
CCTGGATAAGGTGAAGATTCTCTTCTGCAGTCGTGGTGATGCAGATAGGGTGTTTGGTATAACAGGTGAGCCGGATGATG
TTGCGCGTACCCTGCGCGCCCGTTATGGTGTACCTACGGTTGTGTCCACTGCTGGCACACAGGGTGTTTACCTGTCTAGT
GCCACTGGAGAGGAAAGTTTTCCTGTAACCCCGGTGCGGGTTATTGACCGCCCCGGTGCGGGTGATGCTTTCGTCGGCGG
TAGTCTTCATGGTCATCTATCGGGTGATTTGCGCATGGGTATAAAAACCGGGATGCTCGCTGCCCAACATGCCCTCAGTC
ACTATGGTGATTTGGTGTCAACCAGTGCCTTTGGTGAGTATACGAGCACGGATATCCTTCGTTAG

Upstream 100 bases:

>100_bases
ATAGGCGATATTGAGCCTTTGCCTGAGGCCGAAATCAGGCGAAATTATGAGAGATATAAAAATAGATACGGGACTATGTC
CGCGAGTGATGGGGTAAAAA

Downstream 100 bases:

>100_bases
TTCCTTGTTCGTGATCTTCTTGCCCTTGTCTCAATCGATGAGATAGGTTGCGCTTCTTGGGACTCTCACGCTGTACAGTC
ACACTGTAGCCCGTTTGAGA

Product: PfkB-family carbohydrate kinase.

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPRYDVVSLGEGQIRLTVPRGENLLTAKQLYLTAAGSEANVTGLLSQLGHSCAWASVIPKGELGDRIVREYRAVGTDVSH
IVRTDTGRVALYFLQPGADPMPAEVVYDRLHTPFREIEPEIFDWGSLLDTRILFITGITMALTEKTRRVIEYGVACASER
GVDIVLDVNHRARLWSGKEARGVIVPLLDKVKILFCSRGDADRVFGITGEPDDVARTLRARYGVPTVVSTAGTQGVYLSS
ATGEESFPVTPVRVIDRPGAGDAFVGGSLHGHLSGDLRMGIKTGMLAAQHALSHYGDLVSTSAFGEYTSTDILR

Sequences:

>Translated_314_residues
MPRYDVVSLGEGQIRLTVPRGENLLTAKQLYLTAAGSEANVTGLLSQLGHSCAWASVIPKGELGDRIVREYRAVGTDVSH
IVRTDTGRVALYFLQPGADPMPAEVVYDRLHTPFREIEPEIFDWGSLLDTRILFITGITMALTEKTRRVIEYGVACASER
GVDIVLDVNHRARLWSGKEARGVIVPLLDKVKILFCSRGDADRVFGITGEPDDVARTLRARYGVPTVVSTAGTQGVYLSS
ATGEESFPVTPVRVIDRPGAGDAFVGGSLHGHLSGDLRMGIKTGMLAAQHALSHYGDLVSTSAFGEYTSTDILR
>Mature_313_residues
PRYDVVSLGEGQIRLTVPRGENLLTAKQLYLTAAGSEANVTGLLSQLGHSCAWASVIPKGELGDRIVREYRAVGTDVSHI
VRTDTGRVALYFLQPGADPMPAEVVYDRLHTPFREIEPEIFDWGSLLDTRILFITGITMALTEKTRRVIEYGVACASERG
VDIVLDVNHRARLWSGKEARGVIVPLLDKVKILFCSRGDADRVFGITGEPDDVARTLRARYGVPTVVSTAGTQGVYLSSA
TGEESFPVTPVRVIDRPGAGDAFVGGSLHGHLSGDLRMGIKTGMLAAQHALSHYGDLVSTSAFGEYTSTDILR

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 33982; Mature: 33851

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYDVVSLGEGQIRLTVPRGENLLTAKQLYLTAAGSEANVTGLLSQLGHSCAWASVIPK
CCCCEEEEECCCEEEEEECCCCCEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEHHCCCC
GELGDRIVREYRAVGTDVSHIVRTDTGRVALYFLQPGADPMPAEVVYDRLHTPFREIEPE
CCHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHCCC
IFDWGSLLDTRILFITGITMALTEKTRRVIEYGVACASERGVDIVLDVNHRARLWSGKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCC
RGVIVPLLDKVKILFCSRGDADRVFGITGEPDDVARTLRARYGVPTVVSTAGTQGVYLSS
CEEEEEHHCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEC
ATGEESFPVTPVRVIDRPGAGDAFVGGSLHGHLSGDLRMGIKTGMLAAQHALSHYGDLVS
CCCCCCCCCCCEEEEECCCCCCEEECCCEEEEECCCEEECHHHHHHHHHHHHHHHHHHHH
TSAFGEYTSTDILR
HCCCCCCCHHHCCC
>Mature Secondary Structure 
PRYDVVSLGEGQIRLTVPRGENLLTAKQLYLTAAGSEANVTGLLSQLGHSCAWASVIPK
CCCEEEEECCCEEEEEECCCCCEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEHHCCCC
GELGDRIVREYRAVGTDVSHIVRTDTGRVALYFLQPGADPMPAEVVYDRLHTPFREIEPE
CCHHHHHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHCCC
IFDWGSLLDTRILFITGITMALTEKTRRVIEYGVACASERGVDIVLDVNHRARLWSGKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCCCCC
RGVIVPLLDKVKILFCSRGDADRVFGITGEPDDVARTLRARYGVPTVVSTAGTQGVYLSS
CEEEEEHHCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEC
ATGEESFPVTPVRVIDRPGAGDAFVGGSLHGHLSGDLRMGIKTGMLAAQHALSHYGDLVS
CCCCCCCCCCCEEEEECCCCCCEEECCCEEEEECCCEEECHHHHHHHHHHHHHHHHHHHH
TSAFGEYTSTDILR
HCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA