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The map label for this gene is 28572778

Identifier: 28572778

GI number: 28572778

Start: 720115

End: 721752

Strand: Reverse

Name: 28572778

Synonym: TW632

Alternate gene names: NA

Gene position: 721752-720115 (Counterclockwise)

Preceding gene: 28572779

Following gene: 28572777

Centisome position: 77.95

GC content: 47.8

Gene sequence:

>1638_bases
GTGAGTAGTGTTTTGCGGTTAATGCCCCTTGGTGGACTAGGTGAAGTCGGTCGTAATATGACTGTTTTTGAATTAGACGG
TCGTATTTTGCTGGTTGACTGTGGTGTTCTTTTCCCAGATCTCCAACAACCGGGTGTTGATCTTATTCTCCCAGACTTTG
CGCCAATACGCGATAGGCTCGATAAGGTAGAGGCTCTGGTTTTGACTCATGGGCATGAGGATCATATCGGCGCAGTTCCG
TACCTGTTGCGCCTCAGAAGCGATATCCCGCTAATCGGCTCACCTCTTACTTTGGCTTTTGTTGAAGAGAAGTGCAAGGA
GCAGAGACTTTCTCCGAACTTGCGCCGTGTGGCCCCATTAGACCGCTTGAAGGTTGGTGACTTTGACCTTGAGTTTGTGT
CTGTGAATCACTCGATTCCGGATGCAATGGCTGTTTTTATTCGCACTTCTGCGGGGAATATTTTTCATACTGGGGACTTT
AAACTTGATCAGTGGCCTCTTGATAGCAGATTGACCGATCTGCCTTCGTTTGCTCGCTTTGGCGCCGAAGGTGTCGATTT
ATTCATGTGCGACTCGACCAACGCAGATATTGCTGGGTATATTCCCTATGAGCGGGATATTGGTCCGGTTCTGGATTCTC
TTATTGCAAAAACAGAGGGTCGCGCGATAGTTGCCTGCTTTTCAAGTCATGTCGCCAGGGTGCAGCAGGTGCTTAATGCC
GCCGCTGCCAATAACAGGCAGGTGGCATTGCTAGGTCGTTCCATGATCCGCAATATGTCAATCGCGGCACAATTGGGCTT
TTTGCAGGTTCCGGATGGTGTTTTGATAGATGCTGCTATCGCCGAGACTTTACCGTACGATCGTGTGGTGTATGTCTGCA
CGGGCTCCCAGGGCGAACCTCTTGCCGTTCTAAGTCGTATGGCTGACGGGACTTTCCAAATTGTTCCCGGTCCTGGGGAT
AGGGTTATATTTGCATCTAGTTTAATTCCGGGTAATGAGTCATCTGTTTATAAACTGATGGACAAGCTCTACGACCTTGG
TGCTGAGGTTTCACACAAGGGTAACGCATTTGTTCATGTTTCTGGGCACTGTGCATCGGGTGAACTGCTGTACTGCTATA
ACATCCTAAAGCCAAAATTTGCGATGCCAATCCACGGTGAGCGCCGGCATTTGGTTGCTAATAAACGGGTTGCTGAAAAA
AGCGGCATGTCTTCTGATTCTGTTATTTTGGCAAGTAATGGAACTGTTGTTCAGCTGGATGACTCGGGTGCTCGGGTTGT
TGATCAGGTTGACATCGAGCTTGTTTATGTTGATGGGAACAATATTGTAACCGATCGGGAACTTAAGGACAGATTGGCCC
TGTCTGAGGATGGGTTTATTTCGATTACGGTTGTCGTTAACAAAGATTCGGGGGAAATTGTCTCAACTCCGCATATTTAT
ACGAGGGGTTTTGCCGAGGGGTATGAGGTATTTGAGGATGTTGTAAATGAGGTAGTTAGTGAATTGAAACACGCAATCGG
ATCTGGGGTTTTGGATGAACATGATCTCACACGGATTGTTAGGCGTGTTGTTGGTTCATGGGCTGGCCGTAAGATACGAA
GGCATCCGGTTATCGTTCCTCTGGTTGTTACTGTTTGA

Upstream 100 bases:

>100_bases
TTGCATACATGTTAAGTCATGGTGCCTGCTTTTGCTATTATCGTACTGTCCGTTTGCTTAGCGGCTCTTCTTTGTTTGTC
TAGTGTGAGAGTAAATTTCT

Downstream 100 bases:

>100_bases
GTGCAAAGAAGTCGTATCTGAAAGTATGGCGCGGCCTTGCCGGGGCAGCAGGGTCTTGTGCCAGAGTGTTTTCAAAGAAA
TCACTTGCCCGTAGGGATCG

Product: hypothetical protein

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MSSVLRLMPLGGLGEVGRNMTVFELDGRILLVDCGVLFPDLQQPGVDLILPDFAPIRDRLDKVEALVLTHGHEDHIGAVP
YLLRLRSDIPLIGSPLTLAFVEEKCKEQRLSPNLRRVAPLDRLKVGDFDLEFVSVNHSIPDAMAVFIRTSAGNIFHTGDF
KLDQWPLDSRLTDLPSFARFGAEGVDLFMCDSTNADIAGYIPYERDIGPVLDSLIAKTEGRAIVACFSSHVARVQQVLNA
AAANNRQVALLGRSMIRNMSIAAQLGFLQVPDGVLIDAAIAETLPYDRVVYVCTGSQGEPLAVLSRMADGTFQIVPGPGD
RVIFASSLIPGNESSVYKLMDKLYDLGAEVSHKGNAFVHVSGHCASGELLYCYNILKPKFAMPIHGERRHLVANKRVAEK
SGMSSDSVILASNGTVVQLDDSGARVVDQVDIELVYVDGNNIVTDRELKDRLALSEDGFISITVVVNKDSGEIVSTPHIY
TRGFAEGYEVFEDVVNEVVSELKHAIGSGVLDEHDLTRIVRRVVGSWAGRKIRRHPVIVPLVVTV

Sequences:

>Translated_545_residues
MSSVLRLMPLGGLGEVGRNMTVFELDGRILLVDCGVLFPDLQQPGVDLILPDFAPIRDRLDKVEALVLTHGHEDHIGAVP
YLLRLRSDIPLIGSPLTLAFVEEKCKEQRLSPNLRRVAPLDRLKVGDFDLEFVSVNHSIPDAMAVFIRTSAGNIFHTGDF
KLDQWPLDSRLTDLPSFARFGAEGVDLFMCDSTNADIAGYIPYERDIGPVLDSLIAKTEGRAIVACFSSHVARVQQVLNA
AAANNRQVALLGRSMIRNMSIAAQLGFLQVPDGVLIDAAIAETLPYDRVVYVCTGSQGEPLAVLSRMADGTFQIVPGPGD
RVIFASSLIPGNESSVYKLMDKLYDLGAEVSHKGNAFVHVSGHCASGELLYCYNILKPKFAMPIHGERRHLVANKRVAEK
SGMSSDSVILASNGTVVQLDDSGARVVDQVDIELVYVDGNNIVTDRELKDRLALSEDGFISITVVVNKDSGEIVSTPHIY
TRGFAEGYEVFEDVVNEVVSELKHAIGSGVLDEHDLTRIVRRVVGSWAGRKIRRHPVIVPLVVTV
>Mature_544_residues
SSVLRLMPLGGLGEVGRNMTVFELDGRILLVDCGVLFPDLQQPGVDLILPDFAPIRDRLDKVEALVLTHGHEDHIGAVPY
LLRLRSDIPLIGSPLTLAFVEEKCKEQRLSPNLRRVAPLDRLKVGDFDLEFVSVNHSIPDAMAVFIRTSAGNIFHTGDFK
LDQWPLDSRLTDLPSFARFGAEGVDLFMCDSTNADIAGYIPYERDIGPVLDSLIAKTEGRAIVACFSSHVARVQQVLNAA
AANNRQVALLGRSMIRNMSIAAQLGFLQVPDGVLIDAAIAETLPYDRVVYVCTGSQGEPLAVLSRMADGTFQIVPGPGDR
VIFASSLIPGNESSVYKLMDKLYDLGAEVSHKGNAFVHVSGHCASGELLYCYNILKPKFAMPIHGERRHLVANKRVAEKS
GMSSDSVILASNGTVVQLDDSGARVVDQVDIELVYVDGNNIVTDRELKDRLALSEDGFISITVVVNKDSGEIVSTPHIYT
RGFAEGYEVFEDVVNEVVSELKHAIGSGVLDEHDLTRIVRRVVGSWAGRKIRRHPVIVPLVVTV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59480; Mature: 59349

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVLRLMPLGGLGEVGRNMTVFELDGRILLVDCGVLFPDLQQPGVDLILPDFAPIRDRL
CCCCEEECCCCCCHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCEECCCCHHHHHHH
DKVEALVLTHGHEDHIGAVPYLLRLRSDIPLIGSPLTLAFVEEKCKEQRLSPNLRRVAPL
HHHEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCH
DRLKVGDFDLEFVSVNHSIPDAMAVFIRTSAGNIFHTGDFKLDQWPLDSRLTDLPSFARF
HHEEECCCEEEEEEECCCCCCCEEEEEEECCCCEEECCCCEECCCCCCCHHHCCCHHHHC
GAEGVDLFMCDSTNADIAGYIPYERDIGPVLDSLIAKTEGRAIVACFSSHVARVQQVLNA
CCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
AAANNRQVALLGRSMIRNMSIAAQLGFLQVPDGVLIDAAIAETLPYDRVVYVCTGSQGEP
HHCCCCEEEEEEHHHHHHHHHHHHCCEEECCCCCEEHHHHHHHCCCCCEEEEEECCCCCH
LAVLSRMADGTFQIVPGPGDRVIFASSLIPGNESSVYKLMDKLYDLGAEVSHKGNAFVHV
HHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
SGHCASGELLYCYNILKPKFAMPIHGERRHLVANKRVAEKSGMSSDSVILASNGTVVQLD
ECCCCCCCEEEEEECCCCCCCCCCCCCCCEEHHCCHHHHHCCCCCCCEEEECCCCEEEEC
DSGARVVDQVDIELVYVDGNNIVTDRELKDRLALSEDGFISITVVVNKDSGEIVSTPHIY
CCCCEEEEEEEEEEEEECCCCEEECHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCE
TRGFAEGYEVFEDVVNEVVSELKHAIGSGVLDEHDLTRIVRRVVGSWAGRKIRRHPVIVP
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LVVTV
EEEEC
>Mature Secondary Structure 
SSVLRLMPLGGLGEVGRNMTVFELDGRILLVDCGVLFPDLQQPGVDLILPDFAPIRDRL
CCCEEECCCCCCHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCEECCCCHHHHHHH
DKVEALVLTHGHEDHIGAVPYLLRLRSDIPLIGSPLTLAFVEEKCKEQRLSPNLRRVAPL
HHHEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCH
DRLKVGDFDLEFVSVNHSIPDAMAVFIRTSAGNIFHTGDFKLDQWPLDSRLTDLPSFARF
HHEEECCCEEEEEEECCCCCCCEEEEEEECCCCEEECCCCEECCCCCCCHHHCCCHHHHC
GAEGVDLFMCDSTNADIAGYIPYERDIGPVLDSLIAKTEGRAIVACFSSHVARVQQVLNA
CCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
AAANNRQVALLGRSMIRNMSIAAQLGFLQVPDGVLIDAAIAETLPYDRVVYVCTGSQGEP
HHCCCCEEEEEEHHHHHHHHHHHHCCEEECCCCCEEHHHHHHHCCCCCEEEEEECCCCCH
LAVLSRMADGTFQIVPGPGDRVIFASSLIPGNESSVYKLMDKLYDLGAEVSHKGNAFVHV
HHHHHHHCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
SGHCASGELLYCYNILKPKFAMPIHGERRHLVANKRVAEKSGMSSDSVILASNGTVVQLD
ECCCCCCCEEEEEECCCCCCCCCCCCCCCEEHHCCHHHHHCCCCCCCEEEECCCCEEEEC
DSGARVVDQVDIELVYVDGNNIVTDRELKDRLALSEDGFISITVVVNKDSGEIVSTPHIY
CCCCEEEEEEEEEEEEECCCCEEECHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCE
TRGFAEGYEVFEDVVNEVVSELKHAIGSGVLDEHDLTRIVRRVVGSWAGRKIRRHPVIVP
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LVVTV
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]