Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 27363668

GI number: 27363668

Start: 176640

End: 178520

Strand: Reverse

Name: hlyB [H]

Synonym: VV1_0186

Alternate gene names: 27363668

Gene position: 178520-176640 (Counterclockwise)

Preceding gene: 27363669

Following gene: 27363666

Centisome position: 5.44

GC content: 49.39

Gene sequence:

>1881_bases
GTGCTGGTCAGTGCCAACTTGCTGAATTCACTGACGAAAGATATGAACAGGATCGCCTTCGATCTTGCGCCGGACACCGA
GTTGGCAGCAGAAATGACCGATAGCGTTTATGGACTAAGATTAACGGTCAAAAACTTTATCGAGACAGGGGATAAACAAT
TTGTATCTCGTTTCCAAGAGAATGCGTCTCGCTGGACACAGTTTATGGATCGCGCCTATAACGAAATACAAAATCCACAA
CGCGTACAGATCCTTAAAGAGATTGATGGCTTAAAGGCACAGTATCTCACCACGTTTACTCAAGTGGTGGTGAACAATAT
GAATATGCGAAATGAGCAGGTTAATGGTGTGCTCAATGTCGACGGTCCGCAAATAGAGAAAAGACTCACCAGCGTCATGG
AAAGCGCGAAAACCGATGGTGATGTTGTTGCCGCCTATCATGCCGGACGAGCACTCAGATCGCTTTTGCTCGCGCGACTT
TATGTCGCCAAGTTCTTGGTTGAAAACCAGCAGGCACAAGTAGAACGATTCAATCAGGAATTTAAAGCGGTACACAGTGA
GATTGGCAGCTTACTTGCAACGTTGGAAAGCGCACAACGTCGCCAATTGACCAACGAAGCAGAATCGCTGTTTACAAAGT
ATGAAAAAGCGGCCAATTCCGTCACTAGCTTGATTTTTGCCCGTAACGAAGGGATAAAAACGCTGGATACGATCGGGCCG
CAAGTCGCACAACGAATCGCATCGCTTCGTGAGTCGATAGCTAGCTCAATGGAGCAGGCGGCAGAACAAGCTAATGAGAA
TGCAGAACAGTCTATCACCTTTCTTTATGGTATCGCGGCGATTGCTATTGTCATTGGTTTGTTGTTCTCCTTTGTAATCA
CGCGCTCGTTAATTGTTAAAGTACAAAGAACGACCAATGTGCTACAAGATATTGCTCAGGGAGAAGGAGACCTCACCATA
CGCGTGCCCACCAGTGGCAATGATGAACTCGATGTGTTAGCCGGGCATTACAACACCTTCGCTGGCAAACTTCAGCACAC
CATTCGTCAAATGAGCGTAGCGGCCGCACAGATGTTGCAAGCGGCCGAGATTCTGGCATTAAAAGCGCGAGACACACAAA
GTGAGGTGCGAGAGCAGCAATCTCAGGCACAGGTTGCTGCGTCAGCGATGACGGAAATGTCAGCCAGTGCACAAGAGGTG
AGTGCCAGTGCCCAACAGGCGGCGGATCTTTCTCAATCGACGGCCGATTCTGCGACGCAAGGTTCAAAAGTGGTGATGGA
AGCAACGCAGTCAATGCAAAAACTCAACGAGCAAATTGCCAGTGCTGGAGATACGGTTGAACAACTTCGAGCCGACAGTG
AACAAATTGGTACGGTGCTGGATGTTATTCGCAGTATCGCAGAGCAAACCAACTTGCTCGCGCTGAATGCGGCAATTGAA
GCGGCAAGGGCCGGGGAGCAGGGGCGAGGATTTGCGGTGGTGGCGGATGAAGTCCGTTCTTTAGCATCGCGCACTCAAGA
GTCGACCGAAGAAATCCAAACCATCATCGGTAGTTTGCAACAGCGAGCCGAGTTGGCTAACAAGGCGATGCACCAGAGCC
GTCAAAGTGCTGAGCAAACCGCAGAGCAGGTGCACTCGGCAGAATCAGCGTTGACCTCAATCACAGGCTTTATCACCCAG
ATCAACGATTCCATCGGGCAAATATCCACAGCGGCGAATCAGCAGGCAATTGCGTCGGATGAGGTCAGTGTCAATGTGAA
CAATATGTCCGATATCTCGGAGAAGACACTCGTGCAATCGTCTGAAACCACAGAATCCGCTCAGGCGATGAAGCGATTGG
GTGAACAAGTAAACCAGCTACTGAAACAGTTCAAAGTGTAA

Upstream 100 bases:

>100_bases
ATTAACCAAAAGGGAGTCAACAATGGGACTCGATAATATTTCAATTAGCAAGAAGCTCTATTTTTCACCGCTGATTCTTA
TTCTAATTTTATTGGTGATA

Downstream 100 bases:

>100_bases
ACGAGCCAAGTTTGTACAAAAAAAGCGCGCCAATCGTTGGCGCGCTTTTATGCTTTTGCACTTTAGACACAAATTAAGAA
ACTAAGGCTTGTTGTTCTTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MLVSANLLNSLTKDMNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYNEIQNPQ
RVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARL
YVAKFLVENQQAQVERFNQEFKAVHSEIGSLLATLESAQRRQLTNEAESLFTKYEKAANSVTSLIFARNEGIKTLDTIGP
QVAQRIASLRESIASSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQGEGDLTI
RVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSVAAAQMLQAAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEV
SASAQQAADLSQSTADSATQGSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIE
AARAGEQGRGFAVVADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSITGFITQ
INDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLGEQVNQLLKQFKV

Sequences:

>Translated_626_residues
MLVSANLLNSLTKDMNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYNEIQNPQ
RVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARL
YVAKFLVENQQAQVERFNQEFKAVHSEIGSLLATLESAQRRQLTNEAESLFTKYEKAANSVTSLIFARNEGIKTLDTIGP
QVAQRIASLRESIASSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQGEGDLTI
RVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSVAAAQMLQAAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEV
SASAQQAADLSQSTADSATQGSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIE
AARAGEQGRGFAVVADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSITGFITQ
INDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLGEQVNQLLKQFKV
>Mature_626_residues
MLVSANLLNSLTKDMNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQENASRWTQFMDRAYNEIQNPQ
RVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNVDGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARL
YVAKFLVENQQAQVERFNQEFKAVHSEIGSLLATLESAQRRQLTNEAESLFTKYEKAANSVTSLIFARNEGIKTLDTIGP
QVAQRIASLRESIASSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVKVQRTTNVLQDIAQGEGDLTI
RVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSVAAAQMLQAAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEV
SASAQQAADLSQSTADSATQGSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIE
AARAGEQGRGFAVVADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQTAEQVHSAESALTSITGFITQ
INDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQSSETTESAQAMKRLGEQVNQLLKQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=331, Percent_Identity=29.3051359516616, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=29.5081967213115, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=26.7326732673267, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788194, Length=366, Percent_Identity=29.7814207650273, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1789453, Length=207, Percent_Identity=34.7826086956522, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68223; Mature: 68223

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSANLLNSLTKDMNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQE
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NASRWTQFMDRAYNEIQNPQRVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCEEEC
DGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQVERFNQE
CCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
FKAVHSEIGSLLATLESAQRRQLTNEAESLFTKYEKAANSVTSLIFARNEGIKTLDTIGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCH
QVAQRIASLRESIASSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQRTTNVLQDIAQGEGDLTIRVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSVAAAQMLQ
HHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQSTADSATQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
GSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIE
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARAGEQGRGFAVVADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQT
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQVHSAESALTSITGFITQINDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCHHHHHHHHHHCC
SETTESAQAMKRLGEQVNQLLKQFKV
CCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVSANLLNSLTKDMNRIAFDLAPDTELAAEMTDSVYGLRLTVKNFIETGDKQFVSRFQE
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NASRWTQFMDRAYNEIQNPQRVQILKEIDGLKAQYLTTFTQVVVNNMNMRNEQVNGVLNV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCEEEC
DGPQIEKRLTSVMESAKTDGDVVAAYHAGRALRSLLLARLYVAKFLVENQQAQVERFNQE
CCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
FKAVHSEIGSLLATLESAQRRQLTNEAESLFTKYEKAANSVTSLIFARNEGIKTLDTIGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCH
QVAQRIASLRESIASSMEQAAEQANENAEQSITFLYGIAAIAIVIGLLFSFVITRSLIVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQRTTNVLQDIAQGEGDLTIRVPTSGNDELDVLAGHYNTFAGKLQHTIRQMSVAAAQMLQ
HHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEILALKARDTQSEVREQQSQAQVAASAMTEMSASAQEVSASAQQAADLSQSTADSATQ
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCC
GSKVVMEATQSMQKLNEQIASAGDTVEQLRADSEQIGTVLDVIRSIAEQTNLLALNAAIE
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARAGEQGRGFAVVADEVRSLASRTQESTEEIQTIIGSLQQRAELANKAMHQSRQSAEQT
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQVHSAESALTSITGFITQINDSIGQISTAANQQAIASDEVSVNVNNMSDISEKTLVQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEECCHHHHHHHHHHCC
SETTESAQAMKRLGEQVNQLLKQFKV
CCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]