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The map label for this gene is xylB [H]

Identifier: 23501437

GI number: 23501437

Start: 542861

End: 544312

Strand: Reverse

Name: xylB [H]

Synonym: BR0548

Alternate gene names: 23501437

Gene position: 544312-542861 (Counterclockwise)

Preceding gene: 23501438

Following gene: 23501436

Centisome position: 25.82

GC content: 61.85

Gene sequence:

>1452_bases
ATGTATCTGGGTCTCGATTTGGGAACATCCGGCGTCAAGGCGCTTTTGATCGATGAGGCGCAGAACCCGGTCGGCGCGGC
CCATGGCGAACTGGACGTTTCGCGCCCGCATCCCGGCTGGAGCGAACAGGATCCTGCGCAGTGGATCAAAGCCTGCCGTA
CGGCCATAGAAGCCTTGCGCGCGGCGCACCCGAAGGAATTTTCCGCCATTACCGGTATCGGCCTTTCCGGGCAGATGCAT
GGCGCAACCCTGCTGGACGCCGAGGACCGCGTATTGCGCCCCTGCATTCTCTGGAACGATACGCGCAGCTATCGCGAAGC
AGCCGAACTGGATGCCGACCCCGCATTTCACGCCATCACCGGCAATATCGTCTTTCCCGGCTTCACCGCACCGAAACTTG
TCTGGGTCGCACGCAACGAAGCCGATATTTTCGCCCGCATCCGCAAGGTTTTACTGCCGAAAGATTATCTGCGTCTCTGG
CTCACCGGAGAATATATCTCCGACATGTCGGATTCGGCGGGCACAAGCTGGCTCGATACGGGTGCGCGCCGCTGGTCGGC
AGAGCTTCTGGCCAAGACCGGCCTGGGCGAAGGGCAGATGCCGCAACTGGTCGAGGGGAGCGAGGCTGCGGGATGTCTGC
GCGCCGAGCTTGCCGCCGAATGGAGCCTCACCGCATCGGTAATCGTGGCGGGCGGCGCTGGCGACAATGCGGCTTCCGCC
TGCGGCATGGGCACGGTCAAGCCCGGCCATGCCTTCGTTTCACTTGGCACTTCGGGCGTGCTTTTCGCTGCCAATGGCGC
TTACCAGCCAAAACCGGAAAGTGCGGTCCATGCCTTCTGCCACGCCCTGCCCCGCACATGGCACCAGATGGGCGTTATCC
TGTCTGCGGCAAGCGCGCTTGAATGGTATTCAAAAATCGTTGGCGCAACCCCGCAATCGCTCGATCGGGAGCTGGGCGAA
ACCTTGAAAGCACCGGGCAGCGTCACCTTCCTGCCCTATCTTTCAGGCGAGCGCACGCCCTATAATGACGCGAAAATCCG
CGGCTCCTTCTGCGGGCTGGAACATGAAGCCGACCGAAGTGCCCTCACCCAGGCCGTGCTGGAAGGCGTCGCCTTTGCCA
TTCGCGACAATCTTCTTGCCCTGCAATCGGCTGGCACCGAGATTACCTCGCTCACCGCAGTCGGTGGCGGATCACGCTCC
ACCTATTGGCTGAAAGCCATTGCAACAGCATTGAATGTGCCGATTGCACTGCCCGAAGAAGGCGATTTCGGCGCAGCCTT
TGGCGCGGCCCGCCTCGGCCTCATCGCGGCAACCGGGGCCGATCCCTTCACCATCTGCACCCCGCCGCAGACCGCGCGCA
CCATTGAGCCGGAACAGGCGCTGCTTTCAGCTTATGACGAAGCCTATCAGCGTTATCACGCGCTTTATCCGGCGCTCCAT
GCACTTGACTAA

Upstream 100 bases:

>100_bases
TCGTGCCGGGGCAAGAATACATCCGCATTGAAATCTTTCTGAAAGACAACCTGCCCCGCTTCAACTGAAGCAGGCAACAA
GACTTCCAACAGGAGCGATT

Downstream 100 bases:

>100_bases
ACCCTGTCGCGGACGGTGACAATTTCAGAACCTTGAGAGGATGAACATGAGTACGGGATTTTTCGGCGATATTCAGAAGG
TGCGCTATGAGGGGCCGGAG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MYLGLDLGTSGVKALLIDEAQNPVGAAHGELDVSRPHPGWSEQDPAQWIKACRTAIEALRAAHPKEFSAITGIGLSGQMH
GATLLDAEDRVLRPCILWNDTRSYREAAELDADPAFHAITGNIVFPGFTAPKLVWVARNEADIFARIRKVLLPKDYLRLW
LTGEYISDMSDSAGTSWLDTGARRWSAELLAKTGLGEGQMPQLVEGSEAAGCLRAELAAEWSLTASVIVAGGAGDNAASA
CGMGTVKPGHAFVSLGTSGVLFAANGAYQPKPESAVHAFCHALPRTWHQMGVILSAASALEWYSKIVGATPQSLDRELGE
TLKAPGSVTFLPYLSGERTPYNDAKIRGSFCGLEHEADRSALTQAVLEGVAFAIRDNLLALQSAGTEITSLTAVGGGSRS
TYWLKAIATALNVPIALPEEGDFGAAFGAARLGLIAATGADPFTICTPPQTARTIEPEQALLSAYDEAYQRYHALYPALH
ALD

Sequences:

>Translated_483_residues
MYLGLDLGTSGVKALLIDEAQNPVGAAHGELDVSRPHPGWSEQDPAQWIKACRTAIEALRAAHPKEFSAITGIGLSGQMH
GATLLDAEDRVLRPCILWNDTRSYREAAELDADPAFHAITGNIVFPGFTAPKLVWVARNEADIFARIRKVLLPKDYLRLW
LTGEYISDMSDSAGTSWLDTGARRWSAELLAKTGLGEGQMPQLVEGSEAAGCLRAELAAEWSLTASVIVAGGAGDNAASA
CGMGTVKPGHAFVSLGTSGVLFAANGAYQPKPESAVHAFCHALPRTWHQMGVILSAASALEWYSKIVGATPQSLDRELGE
TLKAPGSVTFLPYLSGERTPYNDAKIRGSFCGLEHEADRSALTQAVLEGVAFAIRDNLLALQSAGTEITSLTAVGGGSRS
TYWLKAIATALNVPIALPEEGDFGAAFGAARLGLIAATGADPFTICTPPQTARTIEPEQALLSAYDEAYQRYHALYPALH
ALD
>Mature_483_residues
MYLGLDLGTSGVKALLIDEAQNPVGAAHGELDVSRPHPGWSEQDPAQWIKACRTAIEALRAAHPKEFSAITGIGLSGQMH
GATLLDAEDRVLRPCILWNDTRSYREAAELDADPAFHAITGNIVFPGFTAPKLVWVARNEADIFARIRKVLLPKDYLRLW
LTGEYISDMSDSAGTSWLDTGARRWSAELLAKTGLGEGQMPQLVEGSEAAGCLRAELAAEWSLTASVIVAGGAGDNAASA
CGMGTVKPGHAFVSLGTSGVLFAANGAYQPKPESAVHAFCHALPRTWHQMGVILSAASALEWYSKIVGATPQSLDRELGE
TLKAPGSVTFLPYLSGERTPYNDAKIRGSFCGLEHEADRSALTQAVLEGVAFAIRDNLLALQSAGTEITSLTAVGGGSRS
TYWLKAIATALNVPIALPEEGDFGAAFGAARLGLIAATGADPFTICTPPQTARTIEPEQALLSAYDEAYQRYHALYPALH
ALD

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=440, Percent_Identity=22.2727272727273, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI189409120, Length=440, Percent_Identity=22.5, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4504007, Length=440, Percent_Identity=22.5, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI41393575, Length=443, Percent_Identity=22.7990970654628, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI18860918, Length=523, Percent_Identity=21.9885277246654, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789987, Length=479, Percent_Identity=48.4342379958246, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1790005, Length=496, Percent_Identity=28.0241935483871, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1790361, Length=451, Percent_Identity=22.8381374722838, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787789, Length=506, Percent_Identity=24.1106719367589, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789168, Length=448, Percent_Identity=24.7767857142857, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=424, Percent_Identity=25.7075471698113, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321633, Length=350, Percent_Identity=22.8571428571429, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24655555, Length=460, Percent_Identity=26.304347826087, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24655560, Length=460, Percent_Identity=26.304347826087, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24655570, Length=460, Percent_Identity=26.304347826087, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24655574, Length=460, Percent_Identity=26.304347826087, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24655565, Length=460, Percent_Identity=26.304347826087, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI17864214, Length=466, Percent_Identity=23.3905579399142, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654573, Length=418, Percent_Identity=23.444976076555, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51224; Mature: 51224

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00933 FGGY_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGLDLGTSGVKALLIDEAQNPVGAAHGELDVSRPHPGWSEQDPAQWIKACRTAIEALR
CEEEEECCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
AAHPKEFSAITGIGLSGQMHGATLLDAEDRVLRPCILWNDTRSYREAAELDADPAFHAIT
HCCCCHHHHHCCCCCCCCCCCCEEECCCCHHCCCEEEECCCHHHHHHHHCCCCCCEEEEE
GNIVFPGFTAPKLVWVARNEADIFARIRKVLLPKDYLRLWLTGEYISDMSDSAGTSWLDT
CCEEECCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHEEECHHHHHCCCCCCCCHHHHH
GARRWSAELLAKTGLGEGQMPQLVEGSEAAGCLRAELAAEWSLTASVIVAGGAGDNAASA
HHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHH
CGMGTVKPGHAFVSLGTSGVLFAANGAYQPKPESAVHAFCHALPRTWHQMGVILSAASAL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWYSKIVGATPQSLDRELGETLKAPGSVTFLPYLSGERTPYNDAKIRGSFCGLEHEADRS
HHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCHHCCCCCHHHHH
ALTQAVLEGVAFAIRDNLLALQSAGTEITSLTAVGGGSRSTYWLKAIATALNVPIALPEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEECCCC
GDFGAAFGAARLGLIAATGADPFTICTPPQTARTIEPEQALLSAYDEAYQRYHALYPALH
CCCCHHHHHHHHEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALD
HCC
>Mature Secondary Structure
MYLGLDLGTSGVKALLIDEAQNPVGAAHGELDVSRPHPGWSEQDPAQWIKACRTAIEALR
CEEEEECCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
AAHPKEFSAITGIGLSGQMHGATLLDAEDRVLRPCILWNDTRSYREAAELDADPAFHAIT
HCCCCHHHHHCCCCCCCCCCCCEEECCCCHHCCCEEEECCCHHHHHHHHCCCCCCEEEEE
GNIVFPGFTAPKLVWVARNEADIFARIRKVLLPKDYLRLWLTGEYISDMSDSAGTSWLDT
CCEEECCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHEEECHHHHHCCCCCCCCHHHHH
GARRWSAELLAKTGLGEGQMPQLVEGSEAAGCLRAELAAEWSLTASVIVAGGAGDNAASA
HHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHH
CGMGTVKPGHAFVSLGTSGVLFAANGAYQPKPESAVHAFCHALPRTWHQMGVILSAASAL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWYSKIVGATPQSLDRELGETLKAPGSVTFLPYLSGERTPYNDAKIRGSFCGLEHEADRS
HHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCHHCCCCCHHHHH
ALTQAVLEGVAFAIRDNLLALQSAGTEITSLTAVGGGSRSTYWLKAIATALNVPIALPEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEECCCC
GDFGAAFGAARLGLIAATGADPFTICTPPQTARTIEPEQALLSAYDEAYQRYHALYPALH
CCCCHHHHHHHHEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALD
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]