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The map label for this gene is degA [H]

Identifier: 23501438

GI number: 23501438

Start: 544345

End: 545376

Strand: Reverse

Name: degA [H]

Synonym: BR0549

Alternate gene names: 23501438

Gene position: 545376-544345 (Counterclockwise)

Preceding gene: 23501439

Following gene: 23501437

Centisome position: 25.87

GC content: 59.5

Gene sequence:

>1032_bases
ATGGAACCCACAGTTCATGATATAGCCAGAACAGCGGGCGTAAGCCTCGCCACGGTCGACCGCGTTTTGAATGACCGTCC
CGGTGTCAGAGCCAAAACGCGTGATCGCGTAATGGCCGCAATGAATATGCTGGGCTATGTGCGCGATGTGGGCGCGGCAA
ATCTTGCGCGCGGGCGGCTCTATCAGTTCGATTTCATTTTGCCGGACAACGAAAACACCTTCATGCTGAGCCTGCGTTCG
GAGTTATATGCGGCGAGCGAGCGTGCGCTTGCCGAGCGTGTGCGCATCAACCTGCGGCTGGTTCCAGCCTTCGATGAAGC
AGCACTTGTTGCTGCGCTGGATGAAAGTGCGGCGCGCAAACCGGACGGCGTAGCCTTTGTTGCCCTCGATACCGATCCGG
TACGCGAGGGCTGCGCGCGGCTTGCTGAAAAGGGCATCCATGCGGTTACGCTCGTTTCCGATCTCGGCCAATCTGCGCGC
GAGCATTATGTCGGCGTGGATAACGGGGCTGCGGGCCGCACGGCGGCACGGCTTCTGGGTCTTTTTGCCAATGGAACGGA
GGGCTCGATTGCCGTCGTTGCTGGTTCGCTGAAAGTGCGCGACCACCGCGAACGTTTCGACGGATTCAGGGCGGCGATGC
AGGCGGATTTTCCGGACCGGGAAATATTGCCGGTACTGGAAGGCTTCGATAAAGACCCGCAGGTCGAAAAACTGGTTGGC
GAGCTGCTGGCAAAACGCAGCGATATTGCAGGCATTTACAGTCTGGGCGCGGGCAATAGCGGGCTTGTAGCTGCCCTTTC
GGCACACAAGGCCAACCACCCGCTCGTCATTGCGCATGAGCGCGACGAGATAACCTCAAAGGCGCTTGAAGACGGCATCA
TCCACGCCATTCTGGCGCAGGATGCGGGCCACGAAATCCGCAGCGCCATCCGGGTGCTCAAAGCCTCGGCCGACCGGCTC
GCCATCGTGCCGGGGCAAGAATACATCCGCATTGAAATCTTTCTGAAAGACAACCTGCCCCGCTTCAACTGA

Upstream 100 bases:

>100_bases
CCAGCCCTGTCCTGCTGCAACCGATGATTTGCGACCCTCTTTCATTTTTTTGATTTACGTACCTCATTTTTAATCTTATG
GTCCGCTTCGAGGAGGCGGA

Downstream 100 bases:

>100_bases
AGCAGGCAACAAGACTTCCAACAGGAGCGATTATGTATCTGGGTCTCGATTTGGGAACATCCGGCGTCAAGGCGCTTTTG
ATCGATGAGGCGCAGAACCC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MEPTVHDIARTAGVSLATVDRVLNDRPGVRAKTRDRVMAAMNMLGYVRDVGAANLARGRLYQFDFILPDNENTFMLSLRS
ELYAASERALAERVRINLRLVPAFDEAALVAALDESAARKPDGVAFVALDTDPVREGCARLAEKGIHAVTLVSDLGQSAR
EHYVGVDNGAAGRTAARLLGLFANGTEGSIAVVAGSLKVRDHRERFDGFRAAMQADFPDREILPVLEGFDKDPQVEKLVG
ELLAKRSDIAGIYSLGAGNSGLVAALSAHKANHPLVIAHERDEITSKALEDGIIHAILAQDAGHEIRSAIRVLKASADRL
AIVPGQEYIRIEIFLKDNLPRFN

Sequences:

>Translated_343_residues
MEPTVHDIARTAGVSLATVDRVLNDRPGVRAKTRDRVMAAMNMLGYVRDVGAANLARGRLYQFDFILPDNENTFMLSLRS
ELYAASERALAERVRINLRLVPAFDEAALVAALDESAARKPDGVAFVALDTDPVREGCARLAEKGIHAVTLVSDLGQSAR
EHYVGVDNGAAGRTAARLLGLFANGTEGSIAVVAGSLKVRDHRERFDGFRAAMQADFPDREILPVLEGFDKDPQVEKLVG
ELLAKRSDIAGIYSLGAGNSGLVAALSAHKANHPLVIAHERDEITSKALEDGIIHAILAQDAGHEIRSAIRVLKASADRL
AIVPGQEYIRIEIFLKDNLPRFN
>Mature_343_residues
MEPTVHDIARTAGVSLATVDRVLNDRPGVRAKTRDRVMAAMNMLGYVRDVGAANLARGRLYQFDFILPDNENTFMLSLRS
ELYAASERALAERVRINLRLVPAFDEAALVAALDESAARKPDGVAFVALDTDPVREGCARLAEKGIHAVTLVSDLGQSAR
EHYVGVDNGAAGRTAARLLGLFANGTEGSIAVVAGSLKVRDHRERFDGFRAAMQADFPDREILPVLEGFDKDPQVEKLVG
ELLAKRSDIAGIYSLGAGNSGLVAALSAHKANHPLVIAHERDEITSKALEDGIIHAILAQDAGHEIRSAIRVLKASADRL
AIVPGQEYIRIEIFLKDNLPRFN

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37129; Mature: 37129

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPTVHDIARTAGVSLATVDRVLNDRPGVRAKTRDRVMAAMNMLGYVRDVGAANLARGRL
CCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCE
YQFDFILPDNENTFMLSLRSELYAASERALAERVRINLRLVPAFDEAALVAALDESAARK
EEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCC
PDGVAFVALDTDPVREGCARLAEKGIHAVTLVSDLGQSAREHYVGVDNGAAGRTAARLLG
CCCEEEEEECCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LFANGTEGSIAVVAGSLKVRDHRERFDGFRAAMQADFPDREILPVLEGFDKDPQVEKLVG
HHCCCCCCEEEEEEECEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHH
ELLAKRSDIAGIYSLGAGNSGLVAALSAHKANHPLVIAHERDEITSKALEDGIIHAILAQ
HHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
DAGHEIRSAIRVLKASADRLAIVPGQEYIRIEIFLKDNLPRFN
CCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MEPTVHDIARTAGVSLATVDRVLNDRPGVRAKTRDRVMAAMNMLGYVRDVGAANLARGRL
CCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCE
YQFDFILPDNENTFMLSLRSELYAASERALAERVRINLRLVPAFDEAALVAALDESAARK
EEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCC
PDGVAFVALDTDPVREGCARLAEKGIHAVTLVSDLGQSAREHYVGVDNGAAGRTAARLLG
CCCEEEEEECCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LFANGTEGSIAVVAGSLKVRDHRERFDGFRAAMQADFPDREILPVLEGFDKDPQVEKLVG
HHCCCCCCEEEEEEECEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHH
ELLAKRSDIAGIYSLGAGNSGLVAALSAHKANHPLVIAHERDEITSKALEDGIIHAILAQ
HHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
DAGHEIRSAIRVLKASADRLAIVPGQEYIRIEIFLKDNLPRFN
CCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]