Click here to switch to the map view.

The map label for this gene is xylB [H]

Identifier: 23100573

GI number: 23100573

Start: 3249317

End: 3250816

Strand: Reverse

Name: xylB [H]

Synonym: OB3118

Alternate gene names: 23100573

Gene position: 3250816-3249317 (Counterclockwise)

Preceding gene: 23100574

Following gene: 23100571

Centisome position: 89.54

GC content: 34.8

Gene sequence:

>1500_bases
ATGTCATATGTATTAGGTGTCGATCTTGGAACAAGTGGTGTTAAAGTACTTCTTGTAAATAAAAAAGGTAAAGTAGAATA
TGAAAAAACGAAATCATTAACATTAATACAAGAAAAAACTGGCTATGCTGAACAAGATCCTGATGAATGGGTTAGTCAAA
CATATGAAGCGATTAAAGAATTAGTAACGGATAATGCGGTTGACCCTGCTAAAATTACGGGGTTAAGCTTTGCTGGACAA
ATGCATGGTTTAGTACTATTAAATAATAAAAATCAAGTTATTCGTAACGCAATTTTATGGAATGATACGAGAACTAGCGA
AGAATGCCAAGAAATTTATAGTATTTTAGGGGAAGATCGATTACTAGAAATTACAAAGAATATAGCGCTAGAAGGGTTTA
CTCTTCCTAAATTATTATGGGTGAAAAAGCATGAACCAATTAATTTTGCAAAAACAACGACTTTTTTATTACCAAAGGAT
TATGTTCGTTATCAACTAACTGGAAAATTACACATGGATTATTCTGATGCAGCAGGAACCTTACTGTTGGATGTAGAGAA
GAATAGGTGGAGTAAAGAAATCTGTGAATTATTTGAAATTCCAACTAAAATCTGTCCTGAATTAATAAATTCAATCCAAG
AAGTAGGAACTTTAACAGAAGAAGCATCAACGAATTCGAGGTTAAACATGGCAACAAAAGTATTTGCTGGAGGAGCGGAT
AACGCTTGTGCAGCTATTGGTTCAGGTGTACTTAGTAAGGAGAAAACTCTAGCTAGTATTGGTACTTCCGGTGTTGTGCT
TAGTTATGAAGAATCGGGTGATAAAAAATTTGAAGGTAAAGTTCATTACTTTAATCATGGAGCTCCTGATGCTTTTTATA
CAATGGGAGTAACACTTGCTGCAGGTCACAGCCTTTCTTGGTTTAAGGAGACATTTGCACATGATATATGTTTTGATGAA
TTAATACAAGAAGCATCTACTGTAAATCCTGGAGCTAATGGTTTATTATTTACACCGTATATAAATGGAGAAAGAACCCC
GCATGTGGACGCAAATATTCGAGGGAGTTTTATTGGCATAGACGCATCCCATAAGCGTCAACACTTCACTAGAGCAGTTT
TAGAAGGGATTACCTTTTCCTTGCAAGAAAGTGTAACTATCTTACGGGAAAGTGGAAAGAAAATAGAATCTATTATTTCT
CTAGGTGGAGGAGCAAAAAGTGATTTATGGCTACAAATGCAAGCGGATATCTTTCAAGCAAATGTTATTCGATTAACGAG
TGAGCAAGGACCAGGAATGGGAGCAGCAATGATTGCTAGTGTCGGAGTTGGTTGGTTTAATAGTTTAGCTGACTGCGGTG
ATGTTTTTATTCAAGAAGAAAAGGTATATAAACCAATAGAGGAAAACGTTAAGGTATATCACGATTTATTCCTTTTGTAC
AAGGAAGTATATTCATCAACTACTAAAATAAACAAACAACTTCGTGAATTTAGAAATTAA

Upstream 100 bases:

>100_bases
ATATTTGTTAACGACATTTGCATAATTGGTGTGCAATCATCACATAGAGCAGCAGAGTCTGCTCTATGTGATTGTGTTTA
TATGAAAGGAGATATGTTAG

Downstream 100 bases:

>100_bases
CTTTCTCAGGAATGAGTTAGATGATAAATTTCATACATTTTATTTTAGAATTTGAATATGTTTGCATAGTGTGAACTTCA
GAAGCTATTAAATATATGAG

Product: xylose kinase (xylulokinase)

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSYVLGVDLGTSGVKVLLVNKKGKVEYEKTKSLTLIQEKTGYAEQDPDEWVSQTYEAIKELVTDNAVDPAKITGLSFAGQ
MHGLVLLNNKNQVIRNAILWNDTRTSEECQEIYSILGEDRLLEITKNIALEGFTLPKLLWVKKHEPINFAKTTTFLLPKD
YVRYQLTGKLHMDYSDAAGTLLLDVEKNRWSKEICELFEIPTKICPELINSIQEVGTLTEEASTNSRLNMATKVFAGGAD
NACAAIGSGVLSKEKTLASIGTSGVVLSYEESGDKKFEGKVHYFNHGAPDAFYTMGVTLAAGHSLSWFKETFAHDICFDE
LIQEASTVNPGANGLLFTPYINGERTPHVDANIRGSFIGIDASHKRQHFTRAVLEGITFSLQESVTILRESGKKIESIIS
LGGGAKSDLWLQMQADIFQANVIRLTSEQGPGMGAAMIASVGVGWFNSLADCGDVFIQEEKVYKPIEENVKVYHDLFLLY
KEVYSSTTKINKQLREFRN

Sequences:

>Translated_499_residues
MSYVLGVDLGTSGVKVLLVNKKGKVEYEKTKSLTLIQEKTGYAEQDPDEWVSQTYEAIKELVTDNAVDPAKITGLSFAGQ
MHGLVLLNNKNQVIRNAILWNDTRTSEECQEIYSILGEDRLLEITKNIALEGFTLPKLLWVKKHEPINFAKTTTFLLPKD
YVRYQLTGKLHMDYSDAAGTLLLDVEKNRWSKEICELFEIPTKICPELINSIQEVGTLTEEASTNSRLNMATKVFAGGAD
NACAAIGSGVLSKEKTLASIGTSGVVLSYEESGDKKFEGKVHYFNHGAPDAFYTMGVTLAAGHSLSWFKETFAHDICFDE
LIQEASTVNPGANGLLFTPYINGERTPHVDANIRGSFIGIDASHKRQHFTRAVLEGITFSLQESVTILRESGKKIESIIS
LGGGAKSDLWLQMQADIFQANVIRLTSEQGPGMGAAMIASVGVGWFNSLADCGDVFIQEEKVYKPIEENVKVYHDLFLLY
KEVYSSTTKINKQLREFRN
>Mature_498_residues
SYVLGVDLGTSGVKVLLVNKKGKVEYEKTKSLTLIQEKTGYAEQDPDEWVSQTYEAIKELVTDNAVDPAKITGLSFAGQM
HGLVLLNNKNQVIRNAILWNDTRTSEECQEIYSILGEDRLLEITKNIALEGFTLPKLLWVKKHEPINFAKTTTFLLPKDY
VRYQLTGKLHMDYSDAAGTLLLDVEKNRWSKEICELFEIPTKICPELINSIQEVGTLTEEASTNSRLNMATKVFAGGADN
ACAAIGSGVLSKEKTLASIGTSGVVLSYEESGDKKFEGKVHYFNHGAPDAFYTMGVTLAAGHSLSWFKETFAHDICFDEL
IQEASTVNPGANGLLFTPYINGERTPHVDANIRGSFIGIDASHKRQHFTRAVLEGITFSLQESVTILRESGKKIESIISL
GGGAKSDLWLQMQADIFQANVIRLTSEQGPGMGAAMIASVGVGWFNSLADCGDVFIQEEKVYKPIEENVKVYHDLFLLYK
EVYSSTTKINKQLREFRN

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=444, Percent_Identity=23.1981981981982, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI189409120, Length=442, Percent_Identity=23.0769230769231, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI41393575, Length=447, Percent_Identity=23.7136465324385, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4504007, Length=444, Percent_Identity=23.1981981981982, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI18860918, Length=503, Percent_Identity=22.4652087475149, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789987, Length=442, Percent_Identity=38.6877828054299, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1790005, Length=497, Percent_Identity=23.943661971831, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789168, Length=456, Percent_Identity=24.1228070175439, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787789, Length=516, Percent_Identity=24.031007751938, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790361, Length=496, Percent_Identity=21.9758064516129, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789138, Length=490, Percent_Identity=22.4489795918367, Blast_Score=112, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17535599, Length=455, Percent_Identity=23.7362637362637, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321633, Length=306, Percent_Identity=28.1045751633987, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17864214, Length=470, Percent_Identity=24.6808510638298, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24655555, Length=485, Percent_Identity=23.7113402061856, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655560, Length=485, Percent_Identity=23.7113402061856, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655570, Length=485, Percent_Identity=23.7113402061856, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655574, Length=485, Percent_Identity=23.7113402061856, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655565, Length=485, Percent_Identity=23.7113402061856, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21357867, Length=509, Percent_Identity=22.3968565815324, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654573, Length=377, Percent_Identity=24.6684350132626, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24657106, Length=466, Percent_Identity=24.0343347639485, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24657102, Length=466, Percent_Identity=24.0343347639485, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 55296; Mature: 55164

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVLGVDLGTSGVKVLLVNKKGKVEYEKTKSLTLIQEKTGYAEQDPDEWVSQTYEAIKE
CCEEEEEEECCCCEEEEEECCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
LVTDNAVDPAKITGLSFAGQMHGLVLLNNKNQVIRNAILWNDTRTSEECQEIYSILGEDR
HHCCCCCCCHHCCCEEECCCCCCEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHHCCCH
LLEITKNIALEGFTLPKLLWVKKHEPINFAKTTTFLLPKDYVRYQLTGKLHMDYSDAAGT
HHHHHHHHHCCCCCCHHEEEEECCCCCCHHHHEEEECCCHHEEEEEEEEEEECCCCCCCE
LLLDVEKNRWSKEICELFEIPTKICPELINSIQEVGTLTEEASTNSRLNMATKVFAGGAD
EEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCCC
NACAAIGSGVLSKEKTLASIGTSGVVLSYEESGDKKFEGKVHYFNHGAPDAFYTMGVTLA
CHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCEECCEEEEECCCCCCHHHHHCCCEE
AGHSLSWFKETFAHDICFDELIQEASTVNPGANGLLFTPYINGERTPHVDANIRGSFIGI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEC
DASHKRQHFTRAVLEGITFSLQESVTILRESGKKIESIISLGGGAKSDLWLQMQADIFQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEEHHHHCC
NVIRLTSEQGPGMGAAMIASVGVGWFNSLADCGDVFIQEEKVYKPIEENVKVYHDLFLLY
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHHHHHHHHHH
KEVYSSTTKINKQLREFRN
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SYVLGVDLGTSGVKVLLVNKKGKVEYEKTKSLTLIQEKTGYAEQDPDEWVSQTYEAIKE
CEEEEEEECCCCEEEEEECCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
LVTDNAVDPAKITGLSFAGQMHGLVLLNNKNQVIRNAILWNDTRTSEECQEIYSILGEDR
HHCCCCCCCHHCCCEEECCCCCCEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHHCCCH
LLEITKNIALEGFTLPKLLWVKKHEPINFAKTTTFLLPKDYVRYQLTGKLHMDYSDAAGT
HHHHHHHHHCCCCCCHHEEEEECCCCCCHHHHEEEECCCHHEEEEEEEEEEECCCCCCCE
LLLDVEKNRWSKEICELFEIPTKICPELINSIQEVGTLTEEASTNSRLNMATKVFAGGAD
EEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCCC
NACAAIGSGVLSKEKTLASIGTSGVVLSYEESGDKKFEGKVHYFNHGAPDAFYTMGVTLA
CHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCEECCEEEEECCCCCCHHHHHCCCEE
AGHSLSWFKETFAHDICFDELIQEASTVNPGANGLLFTPYINGERTPHVDANIRGSFIGI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEC
DASHKRQHFTRAVLEGITFSLQESVTILRESGKKIESIISLGGGAKSDLWLQMQADIFQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEEHHHHCC
NVIRLTSEQGPGMGAAMIASVGVGWFNSLADCGDVFIQEEKVYKPIEENVKVYHDLFLLY
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHCCHHHHHHHHHHHHHHH
KEVYSSTTKINKQLREFRN
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]