Click here to switch to the map view.

The map label for this gene is xylA

Identifier: 23100574

GI number: 23100574

Start: 3250892

End: 3252211

Strand: Reverse

Name: xylA

Synonym: OB3119

Alternate gene names: 23100574

Gene position: 3252211-3250892 (Counterclockwise)

Preceding gene: 23100576

Following gene: 23100573

Centisome position: 89.58

GC content: 35.91

Gene sequence:

>1320_bases
ATGAGTTATTTTAATGAAATTGGAACCATTCAGTATGAAGGAGCAAAATCTGACAATCCATTCGCTTTTAAATTCTATAA
CCCAACGGAATCCATTAATGGACAAACAATGGAAGAGCATCTTCGATTTGGGGTCGCATATTGGCATACGTTTACAGAAG
ACTTATCAGATCCATTTGGAAATGGCACAGCAATACGTCCATGGGATAAGTTCAATGGAATGGACTTAGCAAAAGCAAGA
GTGGAAGCAGCATTTGAGTTTTTTGAAAAATTACAAATTCCTTATTTCTGTTTTCATGATGTAGATATTGCTCCAGAGGG
AAGTAGTTTAAAAGAATCTAATGAAAATCTAGATACTGTTGTAGCGATGATTAAAGAGTATATGAAAGATAGTAAAACAA
AATTACTTTGGAATACAGTGAATAATTTTACACATCCTCGTTTTGTTCATGGAGCAGCATCTTCTAATAATGCGGATGTG
TTTGCCTATGCAGCAGCGAAAGTAAAGAAAGGGCTAGAGGTTGGTAAAGAACTTGGAGCTGAAAACTATGTTTTCTGGGG
CGGAAGAGAAGGATATGAAACATTACTTAATACAAATATGAAGCTAGAATTGGATAACTTAGCACGCTTTTTCCATATGG
CCAAAGATTATGCGAATGAAATTGATTTTAATGCACAATTCTTAATTGAACCGAAGCCAAAAGAACCTACTAGTCATCAG
TATGATTTCGATGTAGCTAGCGGGTACGCATTTTTGCAAAACTATGATTTACAAGATACGTTTAAATTTAATATAGAAGC
AAACCATGCAACGTTAGCAGGTCATACATTTGAACATGAGTTACATTATGCACGTATTCATAATATGCTTGGATCTGTTG
ATGCAAACCAAGGACACCCTTTACTAGGGTGGGATACGGACGAATTTCCATCTGATATATATACGACCACATTAGCAATG
TATGAAATTCTAAAAAATGATGGGTTAGGAAAAGGTGGTTTGAACTTTGATGCCAAAGTCAGAAGAGGTTCCTTCACAGC
AGAAGATCTTTTCCATGCACATATAGCAGGAATGGATAGCTTTGCAATAGGATTGAAAGTCGCGCAGCGGTTAATGGATG
ATAGGGTGCTTGAGAATGTTGTTGAGGATCGTTACCGTTCTTTTAACCAAGGGATAGGGAGAGATATTGTTTCTGGAAAA
ACAGATTTCCATCAATTAGAGAAACACGCCTTAACACTATCTGAAATTACACAACCTTCAGGTCAATTGGAAGTTATTAA
GAATAAAATCAATCAATATTTGTTAACGACATTTGCATAA

Upstream 100 bases:

>100_bases
TTCTTTGTAAGGGGTATCATATATAGATAGTATAGGGACAATCTGTTTATCTATCAACTTTGTTTGTTAGATAAACAAAC
ATTTTGAGGAGGAATTAATG

Downstream 100 bases:

>100_bases
TTGGTGTGCAATCATCACATAGAGCAGCAGAGTCTGCTCTATGTGATTGTGTTTATATGAAAGGAGATATGTTAGATGTC
ATATGTATTAGGTGTCGATC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSYFNEIGTIQYEGAKSDNPFAFKFYNPTESINGQTMEEHLRFGVAYWHTFTEDLSDPFGNGTAIRPWDKFNGMDLAKAR
VEAAFEFFEKLQIPYFCFHDVDIAPEGSSLKESNENLDTVVAMIKEYMKDSKTKLLWNTVNNFTHPRFVHGAASSNNADV
FAYAAAKVKKGLEVGKELGAENYVFWGGREGYETLLNTNMKLELDNLARFFHMAKDYANEIDFNAQFLIEPKPKEPTSHQ
YDFDVASGYAFLQNYDLQDTFKFNIEANHATLAGHTFEHELHYARIHNMLGSVDANQGHPLLGWDTDEFPSDIYTTTLAM
YEILKNDGLGKGGLNFDAKVRRGSFTAEDLFHAHIAGMDSFAIGLKVAQRLMDDRVLENVVEDRYRSFNQGIGRDIVSGK
TDFHQLEKHALTLSEITQPSGQLEVIKNKINQYLLTTFA

Sequences:

>Translated_439_residues
MSYFNEIGTIQYEGAKSDNPFAFKFYNPTESINGQTMEEHLRFGVAYWHTFTEDLSDPFGNGTAIRPWDKFNGMDLAKAR
VEAAFEFFEKLQIPYFCFHDVDIAPEGSSLKESNENLDTVVAMIKEYMKDSKTKLLWNTVNNFTHPRFVHGAASSNNADV
FAYAAAKVKKGLEVGKELGAENYVFWGGREGYETLLNTNMKLELDNLARFFHMAKDYANEIDFNAQFLIEPKPKEPTSHQ
YDFDVASGYAFLQNYDLQDTFKFNIEANHATLAGHTFEHELHYARIHNMLGSVDANQGHPLLGWDTDEFPSDIYTTTLAM
YEILKNDGLGKGGLNFDAKVRRGSFTAEDLFHAHIAGMDSFAIGLKVAQRLMDDRVLENVVEDRYRSFNQGIGRDIVSGK
TDFHQLEKHALTLSEITQPSGQLEVIKNKINQYLLTTFA
>Mature_438_residues
SYFNEIGTIQYEGAKSDNPFAFKFYNPTESINGQTMEEHLRFGVAYWHTFTEDLSDPFGNGTAIRPWDKFNGMDLAKARV
EAAFEFFEKLQIPYFCFHDVDIAPEGSSLKESNENLDTVVAMIKEYMKDSKTKLLWNTVNNFTHPRFVHGAASSNNADVF
AYAAAKVKKGLEVGKELGAENYVFWGGREGYETLLNTNMKLELDNLARFFHMAKDYANEIDFNAQFLIEPKPKEPTSHQY
DFDVASGYAFLQNYDLQDTFKFNIEANHATLAGHTFEHELHYARIHNMLGSVDANQGHPLLGWDTDEFPSDIYTTTLAMY
EILKNDGLGKGGLNFDAKVRRGSFTAEDLFHAHIAGMDSFAIGLKVAQRLMDDRVLENVVEDRYRSFNQGIGRDIVSGKT
DFHQLEKHALTLSEITQPSGQLEVIKNKINQYLLTTFA

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=437, Percent_Identity=48.2837528604119, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_OCEIH (Q8ELU7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_694041.1
- ProteinModelPortal:   Q8ELU7
- SMR:   Q8ELU7
- GeneID:   1017853
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3119
- NMPDR:   fig|221109.1.peg.3122
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- BioCyc:   OIHE221109:OB3119-MONOMER
- BRENDA:   5.3.1.5
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49881; Mature: 49750

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 99-99 ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFNEIGTIQYEGAKSDNPFAFKFYNPTESINGQTMEEHLRFGVAYWHTFTEDLSDPFG
CCCHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NGTAIRPWDKFNGMDLAKARVEAAFEFFEKLQIPYFCFHDVDIAPEGSSLKESNENLDTV
CCCEECCHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHH
VAMIKEYMKDSKTKLLWNTVNNFTHPRFVHGAASSNNADVFAYAAAKVKKGLEVGKELGA
HHHHHHHHHCCCCEEHHHHHHCCCCCCEEECCCCCCCCCEEEHHHHHHHHHHHHHHHCCC
ENYVFWGGREGYETLLNTNMKLELDNLARFFHMAKDYANEIDFNAQFLIEPKPKEPTSHQ
CCEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
YDFDVASGYAFLQNYDLQDTFKFNIEANHATLAGHTFEHELHYARIHNMLGSVDANQGHP
CCCCHHCCCHHHHCCCCCCEEEEEEEECCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
LLGWDTDEFPSDIYTTTLAMYEILKNDGLGKGGLNFDAKVRRGSFTAEDLFHAHIAGMDS
EECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHCCHH
FAIGLKVAQRLMDDRVLENVVEDRYRSFNQGIGRDIVSGKTDFHQLEKHALTLSEITQPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCC
GQLEVIKNKINQYLLTTFA
CHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SYFNEIGTIQYEGAKSDNPFAFKFYNPTESINGQTMEEHLRFGVAYWHTFTEDLSDPFG
CCHHCCCCEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
NGTAIRPWDKFNGMDLAKARVEAAFEFFEKLQIPYFCFHDVDIAPEGSSLKESNENLDTV
CCCEECCHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHH
VAMIKEYMKDSKTKLLWNTVNNFTHPRFVHGAASSNNADVFAYAAAKVKKGLEVGKELGA
HHHHHHHHHCCCCEEHHHHHHCCCCCCEEECCCCCCCCCEEEHHHHHHHHHHHHHHHCCC
ENYVFWGGREGYETLLNTNMKLELDNLARFFHMAKDYANEIDFNAQFLIEPKPKEPTSHQ
CCEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
YDFDVASGYAFLQNYDLQDTFKFNIEANHATLAGHTFEHELHYARIHNMLGSVDANQGHP
CCCCHHCCCHHHHCCCCCCEEEEEEEECCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
LLGWDTDEFPSDIYTTTLAMYEILKNDGLGKGGLNFDAKVRRGSFTAEDLFHAHIAGMDS
EECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHCCHH
FAIGLKVAQRLMDDRVLENVVEDRYRSFNQGIGRDIVSGKTDFHQLEKHALTLSEITQPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCC
GQLEVIKNKINQYLLTTFA
CHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376