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The map label for this gene is ykhA [H]

Identifier: 23100499

GI number: 23100499

Start: 3157153

End: 3157668

Strand: Reverse

Name: ykhA [H]

Synonym: OB3044

Alternate gene names: 23100499

Gene position: 3157668-3157153 (Counterclockwise)

Preceding gene: 23100500

Following gene: 23100497

Centisome position: 86.98

GC content: 38.37

Gene sequence:

>516_bases
ATGGAAGCAAAACCTTGTTCTGCATCACTAGCAATAAAGACGACACATGTACTTCCACCGGATACGAATCCTTATAACAC
ATTATTTGGTGGAAAACTAATGGCACATTTAGATGATATAGCAGGCATTGCCGCTGTGAAGCATGCTAATAACCCCGTTG
TGACTGCATCTACAGATTCAGTCGACTTTTTAGCACCGGTACGAGTTGGACAATATATTTCAATTGAAGCATTTGTAACA
TGGACACATAATACTTCTATGGAAGTATTTATTCGTGCAATTACAGAAGATATTAAAACAGGAGATAGAAAAGCTTGTAC
GACTGCTTTTATGACATTTGTCGCGATTGATGAAAATGGCAAACCGATCTCGGTTCCTCCTGTATATCCAGAAAATGAAG
ATGAAAAGATGCTGCATGAAAGTGCACCTTTACGAGCAAATCGTCGTGAAGAGAGAAGACTTAATTCAAAAAAACTTGCA
GAAACATTTGGGACAACCTACCGTACAGAGAAATAA

Upstream 100 bases:

>100_bases
AAAGAATCTATATCCAGGTTGATTTCACCTGTTTTATAAATTATAGAGAATAGAATCATGTATACAACATAATGAAAAAG
CATAATAGGAGTGAATTTGA

Downstream 100 bases:

>100_bases
AATAGTAGATAATAATAAACGGATGCAGACTTCTCATCGAAGCTTGCATCCGTTTTAATGTTGTTCTACCTCTTCAGCTG
AGATATACTCGTCAGCCCAT

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MEAKPCSASLAIKTTHVLPPDTNPYNTLFGGKLMAHLDDIAGIAAVKHANNPVVTASTDSVDFLAPVRVGQYISIEAFVT
WTHNTSMEVFIRAITEDIKTGDRKACTTAFMTFVAIDENGKPISVPPVYPENEDEKMLHESAPLRANRREERRLNSKKLA
ETFGTTYRTEK

Sequences:

>Translated_171_residues
MEAKPCSASLAIKTTHVLPPDTNPYNTLFGGKLMAHLDDIAGIAAVKHANNPVVTASTDSVDFLAPVRVGQYISIEAFVT
WTHNTSMEVFIRAITEDIKTGDRKACTTAFMTFVAIDENGKPISVPPVYPENEDEKMLHESAPLRANRREERRLNSKKLA
ETFGTTYRTEK
>Mature_171_residues
MEAKPCSASLAIKTTHVLPPDTNPYNTLFGGKLMAHLDDIAGIAAVKHANNPVVTASTDSVDFLAPVRVGQYISIEAFVT
WTHNTSMEVFIRAITEDIKTGDRKACTTAFMTFVAIDENGKPISVPPVYPENEDEKMLHESAPLRANRREERRLNSKKLA
ETFGTTYRTEK

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528284, Length=139, Percent_Identity=32.3741007194245, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI32528286, Length=139, Percent_Identity=32.3741007194245, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI32528282, Length=139, Percent_Identity=32.3741007194245, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI75709208, Length=139, Percent_Identity=32.3741007194245, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI22165400, Length=136, Percent_Identity=38.2352941176471, Blast_Score=80, Evalue=8e-16,
Organism=Homo sapiens, GI18640736, Length=136, Percent_Identity=37.5, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI22165355, Length=136, Percent_Identity=38.2352941176471, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1787506, Length=115, Percent_Identity=33.0434782608696, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 18924; Mature: 18924

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKPCSASLAIKTTHVLPPDTNPYNTLFGGKLMAHLDDIAGIAAVKHANNPVVTASTDS
CCCCCCCCEEEEEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHEECCCCCEEEECCCC
VDFLAPVRVGQYISIEAFVTWTHNTSMEVFIRAITEDIKTGDRKACTTAFMTFVAIDENG
CEEEECCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHEEEEEEEECCCC
KPISVPPVYPENEDEKMLHESAPLRANRREERRLNSKKLAETFGTTYRTEK
CEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEAKPCSASLAIKTTHVLPPDTNPYNTLFGGKLMAHLDDIAGIAAVKHANNPVVTASTDS
CCCCCCCCEEEEEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHHHEECCCCCEEEECCCC
VDFLAPVRVGQYISIEAFVTWTHNTSMEVFIRAITEDIKTGDRKACTTAFMTFVAIDENG
CEEEECCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHEEEEEEEECCCC
KPISVPPVYPENEDEKMLHESAPLRANRREERRLNSKKLAETFGTTYRTEK
CEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]