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The map label for this gene is 23100497

Identifier: 23100497

GI number: 23100497

Start: 3155336

End: 3156577

Strand: Reverse

Name: 23100497

Synonym: OB3042

Alternate gene names: NA

Gene position: 3156577-3155336 (Counterclockwise)

Preceding gene: 23100499

Following gene: 23100495

Centisome position: 86.95

GC content: 37.28

Gene sequence:

>1242_bases
ATGACTAGTAAACATACACAGGAAAAATATGCGGAATTAACACTTAAAAAAGGAGTTAATTTACAAAAGGGTCAAGCAGT
AATGATTAATGCTCCTATAGAAGGAGCTGATTTTACTCGAATTGTTGCTCGTAAAGCATACGAATTAGGTGCTAAAGATG
TACATATTAATTGGATGGATGATGAGTTAACTTTATTAAAGTATCAATACGCACCGGACGAAGTCATCGAACACTATCCA
GATTGGAAAGTGAAATTACATGATTCGTTTGCAGAAGATGGTGCTGCAGTAGTAAATATTCGTGCTACTGACCCGGATTT
ACTAAAAGACATAGATCCATCTAAAGTCGCTAAAGCAAATAAAGCTGCTGCGCAAGCAATGGTAAACTTTCGAAAGTATA
CGATGAATGATAAGATTCCTTGGACGATTATTTCAATTCCATCGAAAGCATGGGCAAAGAAAATTTTCCCAAACAAATCA
GAAGCAGAAGCAGTGGAAAGTTTATGGGAGGCAATCTTAAAAATTGTACGAGTAGACCAAGAAGATCCTGTTGCAGCTTG
GGATCAACATAATGAAACATTAAAGACAGCTCGAGAAGTTTTAAATGATAAAGACTACAAAAAATTAATTTTTAAAGCTC
CAGGCACAGATCTAGAGATGGAGCTACCGGATGGTCATATATGGAAAGGTGGATCTGCTGAAGCGGAATCAGGGATCAGT
TTTAATCCAAATATGCCTACGGAAGAAGTGTTCTCTTTACCGCATAAGTATGGTGTAAATGGAACTGTCTCAAGTACGAA
GCCATTAAATTATGGTGGAAGTTTAATCGATAATTTCACATTGACGTTTAAAGATGGAAAAGTTGTTGATTACAAAGCAG
AGCAAGGAGAAGCTGTCTTAAAACATTTATTAGACTCGGATGAAGGAGCAGTTCGTTTAGGAGAAATAGCGTTAGTGCCA
CATGAGTCTCCAGTATCCCAGTCAGGATTAATTTTCTATAATACTTTATTTGATGAGAATGCGTCTTGCCATATTGCACT
GGGTAAAGCATATCCAACGAACCTAAAAGGCGGTTCTGCAATGGATCTAGATGAACTAGATAAACATGGTGTAAACGATA
GTCTTATCCATGTAGACTTTATGATAGGTTCGGAGCAGATGGATATTGATGGTGTGAAAGCAGATGGTACAACAGAGCCG
GTGTTTAGAAATGGAACATGGGCACTTAATATTAAAGGATAA

Upstream 100 bases:

>100_bases
ACGTTATCTCGTATAGGAATATAAATTTTGGCAATTTTCCGTTGAATATGAAATAATAGAAAGGATGAAAGATTATAGAT
CATTTTGTGGAGGTTAGACA

Downstream 100 bases:

>100_bases
CGAAGCTAATAATCGCTGTCTGCAATGCAAATCAAGCAGCTGTAGATTCAGTAATGGATGCAAGTTAAAATAAATAGGCG
GCTTCCTTGGGTGATGACCC

Product: aminopeptidase II

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTSKHTQEKYAELTLKKGVNLQKGQAVMINAPIEGADFTRIVARKAYELGAKDVHINWMDDELTLLKYQYAPDEVIEHYP
DWKVKLHDSFAEDGAAVVNIRATDPDLLKDIDPSKVAKANKAAAQAMVNFRKYTMNDKIPWTIISIPSKAWAKKIFPNKS
EAEAVESLWEAILKIVRVDQEDPVAAWDQHNETLKTAREVLNDKDYKKLIFKAPGTDLEMELPDGHIWKGGSAEAESGIS
FNPNMPTEEVFSLPHKYGVNGTVSSTKPLNYGGSLIDNFTLTFKDGKVVDYKAEQGEAVLKHLLDSDEGAVRLGEIALVP
HESPVSQSGLIFYNTLFDENASCHIALGKAYPTNLKGGSAMDLDELDKHGVNDSLIHVDFMIGSEQMDIDGVKADGTTEP
VFRNGTWALNIKG

Sequences:

>Translated_413_residues
MTSKHTQEKYAELTLKKGVNLQKGQAVMINAPIEGADFTRIVARKAYELGAKDVHINWMDDELTLLKYQYAPDEVIEHYP
DWKVKLHDSFAEDGAAVVNIRATDPDLLKDIDPSKVAKANKAAAQAMVNFRKYTMNDKIPWTIISIPSKAWAKKIFPNKS
EAEAVESLWEAILKIVRVDQEDPVAAWDQHNETLKTAREVLNDKDYKKLIFKAPGTDLEMELPDGHIWKGGSAEAESGIS
FNPNMPTEEVFSLPHKYGVNGTVSSTKPLNYGGSLIDNFTLTFKDGKVVDYKAEQGEAVLKHLLDSDEGAVRLGEIALVP
HESPVSQSGLIFYNTLFDENASCHIALGKAYPTNLKGGSAMDLDELDKHGVNDSLIHVDFMIGSEQMDIDGVKADGTTEP
VFRNGTWALNIKG
>Mature_412_residues
TSKHTQEKYAELTLKKGVNLQKGQAVMINAPIEGADFTRIVARKAYELGAKDVHINWMDDELTLLKYQYAPDEVIEHYPD
WKVKLHDSFAEDGAAVVNIRATDPDLLKDIDPSKVAKANKAAAQAMVNFRKYTMNDKIPWTIISIPSKAWAKKIFPNKSE
AEAVESLWEAILKIVRVDQEDPVAAWDQHNETLKTAREVLNDKDYKKLIFKAPGTDLEMELPDGHIWKGGSAEAESGISF
NPNMPTEEVFSLPHKYGVNGTVSSTKPLNYGGSLIDNFTLTFKDGKVVDYKAEQGEAVLKHLLDSDEGAVRLGEIALVPH
ESPVSQSGLIFYNTLFDENASCHIALGKAYPTNLKGGSAMDLDELDKHGVNDSLIHVDFMIGSEQMDIDGVKADGTTEPV
FRNGTWALNIKG

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 45730; Mature: 45599

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKHTQEKYAELTLKKGVNLQKGQAVMINAPIEGADFTRIVARKAYELGAKDVHINWMD
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEC
DELTLLKYQYAPDEVIEHYPDWKVKLHDSFAEDGAAVVNIRATDPDLLKDIDPSKVAKAN
CCEEEEEEECCCHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHH
KAAAQAMVNFRKYTMNDKIPWTIISIPSKAWAKKIFPNKSEAEAVESLWEAILKIVRVDQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
EDPVAAWDQHNETLKTAREVLNDKDYKKLIFKAPGTDLEMELPDGHIWKGGSAEAESGIS
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEECCCCCCCCCCCE
FNPNMPTEEVFSLPHKYGVNGTVSSTKPLNYGGSLIDNFTLTFKDGKVVDYKAEQGEAVL
ECCCCCHHHHHCCCHHCCCCCCCCCCCCCCCCCCEEECEEEEEECCEEEEEECCCHHHHH
KHLLDSDEGAVRLGEIALVPHESPVSQSGLIFYNTLFDENASCHIALGKAYPTNLKGGSA
HHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCC
MDLDELDKHGVNDSLIHVDFMIGSEQMDIDGVKADGTTEPVFRNGTWALNIKG
CCHHHHHHCCCCCCEEEEEEEECCCCCCCCCEECCCCCCCEEECCEEEEEECC
>Mature Secondary Structure 
TSKHTQEKYAELTLKKGVNLQKGQAVMINAPIEGADFTRIVARKAYELGAKDVHINWMD
CCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEEC
DELTLLKYQYAPDEVIEHYPDWKVKLHDSFAEDGAAVVNIRATDPDLLKDIDPSKVAKAN
CCEEEEEEECCCHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHH
KAAAQAMVNFRKYTMNDKIPWTIISIPSKAWAKKIFPNKSEAEAVESLWEAILKIVRVDQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
EDPVAAWDQHNETLKTAREVLNDKDYKKLIFKAPGTDLEMELPDGHIWKGGSAEAESGIS
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEECCCCCCCCCCCE
FNPNMPTEEVFSLPHKYGVNGTVSSTKPLNYGGSLIDNFTLTFKDGKVVDYKAEQGEAVL
ECCCCCHHHHHCCCHHCCCCCCCCCCCCCCCCCCEEECEEEEEECCEEEEEECCCHHHHH
KHLLDSDEGAVRLGEIALVPHESPVSQSGLIFYNTLFDENASCHIALGKAYPTNLKGGSA
HHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCC
MDLDELDKHGVNDSLIHVDFMIGSEQMDIDGVKADGTTEPVFRNGTWALNIKG
CCHHHHHHCCCCCCEEEEEEEECCCCCCCCCEECCCCCCCEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]