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The map label for this gene is pdxS

Identifier: 23100142

GI number: 23100142

Start: 2756980

End: 2757867

Strand: Reverse

Name: pdxS

Synonym: OB2687

Alternate gene names: 23100142

Gene position: 2757867-2756980 (Counterclockwise)

Preceding gene: 23100148

Following gene: 23100141

Centisome position: 75.96

GC content: 41.55

Gene sequence:

>888_bases
ATGGAAAGAAAACTTGGTACAGATCGAGTTAAAAGAGGAATGGCTCAAATGCAAAAAGGCGGAGTAATCATGGATGTTGT
CAATAGTGAACAGGCTAAGATAGCTGAACAAGCAGGCGCGGTTGCTGTTATGGCATTGGAACGAGTACCATCTGATATTC
GTGCTGCTGGTGGAGTTGCAAGGATGGCAAATCCGAGCTTAGTAGAAGAAATTATTCAATCCGTATCGATTCCTGTAATG
GCGAAAGCACGTATAGGTCATATTGTAGAAGCAAGAGTATTAGAATCTTTGGGAGTTGATTATATCGATGAAAGTGAAGT
GTTAACTCCAGCAGATGAAGTATTTCATTTAAATAAGTCTGATTATACAGTTCCGTTTGTTTGTGGTTGCAGAGACTTAG
GTGAAGCAGCAAGGAGAATTGGAGAAGGAGCAGCAATGCTACGTACGAAAGGAGAACCGGGTACAGGGAATATTGTGGAA
GCGGTTCGTCATATACGAGAGGTTCAAGCGCAAGTCAACAAAGTTGTTCATATGAGCAAAGATGAATTAATGACAGAAGC
AAAAAATCTTGGAGCACCGTATGAGATACTTTTGCAAATTAAAGAAAATGGTAGATTACCAGTCGTTAATTTTGCAGCAG
GAGGAGTAGCTACACCAGCAGACGCTGCGTTGATGATGGAATTAGGAGCAGACGGTGTGTTTGTTGGATCTGGTATCTTT
AAATCTCATCATCCTGAGAAGTTTGCCCGTGCGATTGTACAAGCAACTACGTATTTTGACGATTATGAACGTATTGCAGA
AGTATCAAAAGATCTAGGGGAAGCGATGACAGGGATAGATGTGCATTCTCTAGCTGCTGATCAACGTATGCAAGAACGTG
GTTGGTAA

Upstream 100 bases:

>100_bases
GACCTTATCAAATTATAAGAAATTGGCACTTTTAAACATATCAATCTATTTTTATAATAATAAAAAATCATCAGAAAATC
TATTAGGAGGAGTGGGATTT

Downstream 100 bases:

>100_bases
TAACGTAAAGGGTGGTGAATAGCATGTGCAATTCTTTTCGTATAGGAGTATTGGGCTTACAAGGGGCCATAAGTGAACAT
GTAAACCGGTTAAAGGAATT

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MERKLGTDRVKRGMAQMQKGGVIMDVVNSEQAKIAEQAGAVAVMALERVPSDIRAAGGVARMANPSLVEEIIQSVSIPVM
AKARIGHIVEARVLESLGVDYIDESEVLTPADEVFHLNKSDYTVPFVCGCRDLGEAARRIGEGAAMLRTKGEPGTGNIVE
AVRHIREVQAQVNKVVHMSKDELMTEAKNLGAPYEILLQIKENGRLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSHHPEKFARAIVQATTYFDDYERIAEVSKDLGEAMTGIDVHSLAADQRMQERGW

Sequences:

>Translated_295_residues
MERKLGTDRVKRGMAQMQKGGVIMDVVNSEQAKIAEQAGAVAVMALERVPSDIRAAGGVARMANPSLVEEIIQSVSIPVM
AKARIGHIVEARVLESLGVDYIDESEVLTPADEVFHLNKSDYTVPFVCGCRDLGEAARRIGEGAAMLRTKGEPGTGNIVE
AVRHIREVQAQVNKVVHMSKDELMTEAKNLGAPYEILLQIKENGRLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSHHPEKFARAIVQATTYFDDYERIAEVSKDLGEAMTGIDVHSLAADQRMQERGW
>Mature_295_residues
MERKLGTDRVKRGMAQMQKGGVIMDVVNSEQAKIAEQAGAVAVMALERVPSDIRAAGGVARMANPSLVEEIIQSVSIPVM
AKARIGHIVEARVLESLGVDYIDESEVLTPADEVFHLNKSDYTVPFVCGCRDLGEAARRIGEGAAMLRTKGEPGTGNIVE
AVRHIREVQAQVNKVVHMSKDELMTEAKNLGAPYEILLQIKENGRLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSHHPEKFARAIVQATTYFDDYERIAEVSKDLGEAMTGIDVHSLAADQRMQERGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=291, Percent_Identity=58.0756013745705, Blast_Score=353, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6321049, Length=294, Percent_Identity=58.5034013605442, Blast_Score=346, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6323996, Length=294, Percent_Identity=58.1632653061224, Blast_Score=346, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_OCEIH (Q8EN03)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693608.1
- ProteinModelPortal:   Q8EN03
- SMR:   Q8EN03
- GeneID:   1017044
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2687
- NMPDR:   fig|221109.1.peg.2687
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- BioCyc:   OIHE221109:OB2687-MONOMER
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31867; Mature: 31867

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKLGTDRVKRGMAQMQKGGVIMDVVNSEQAKIAEQAGAVAVMALERVPSDIRAAGGVA
CCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHHHCCHH
RMANPSLVEEIIQSVSIPVMAKARIGHIVEARVLESLGVDYIDESEVLTPADEVFHLNKS
HCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCC
DYTVPFVCGCRDLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHIREVQAQVNKVVHMSK
CCCEEEEECCHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
DELMTEAKNLGAPYEILLQIKENGRLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
HHHHHHHHHCCCCHHHEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCH
KSHHPEKFARAIVQATTYFDDYERIAEVSKDLGEAMTGIDVHSLAADQRMQERGW
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERKLGTDRVKRGMAQMQKGGVIMDVVNSEQAKIAEQAGAVAVMALERVPSDIRAAGGVA
CCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHHHCCHH
RMANPSLVEEIIQSVSIPVMAKARIGHIVEARVLESLGVDYIDESEVLTPADEVFHLNKS
HCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCC
DYTVPFVCGCRDLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHIREVQAQVNKVVHMSK
CCCEEEEECCHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
DELMTEAKNLGAPYEILLQIKENGRLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
HHHHHHHHHCCCCHHHEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCH
KSHHPEKFARAIVQATTYFDDYERIAEVSKDLGEAMTGIDVHSLAADQRMQERGW
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376