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The map label for this gene is bcd [H]

Identifier: 23098319

GI number: 23098319

Start: 916448

End: 917644

Strand: Reverse

Name: bcd [H]

Synonym: OB0864

Alternate gene names: 23098319

Gene position: 917644-916448 (Counterclockwise)

Preceding gene: 23098320

Following gene: 23098315

Centisome position: 25.28

GC content: 38.93

Gene sequence:

>1197_bases
ATGGATTTTCATTTTAGCGAGGAACAACAACTATTAAGAAAGACAGTCAGAGATTTTACTGACAAGGAAATTATGCCTTA
TATTAGCGAATGGGATCGTAATGGCAAATTTGACCCGACTCTATTAAATAAATTAGCGGAATTAGGTTTAATGGGTGTAT
GTATTCCCGAACAATATGGTGGTAGTGGAATGGACTATAATTCACTTGCCATTGTATGCGAAGAATTGGAACGTGGCGAT
ACAGCTTTTCGAACTGCCGTTTCGGTGCATACTGGTCTGAACAGTATGACATTATTGCAATGGGGAAATGAACAACAAAA
ACAAAAATACCTTATCCCCCAAGCAAAAGGCGAAAAAATTGGGGCCTTTGGATTAACAGAGCCCGGTGCTGGATCCGATG
TTGCTGCTCTTCAATCGACAGCGGTAAAGCAAGGAGATCATTATATTTTAAATGGACAAAAAACATGGATTTCTCTTTGT
GATATCGCAGATCATTTCATTGTTTTCGCCTATACAAAGGACCGATCCGAAAAACATAAAGGAATATCTGCATTTATCGT
GGAAAGATCTTGGGAAGGGTTCTCTTCTAAAGCAATCAAAGGAAAACATGGTATTCGATCTGGAAATACTGGGGAAATAT
TCTTTGACCATATTAAAGTGCCAAAAGAAAATTTGCTCGGTAAAGAAGGAGAAGGATTTAAGATTGCCATGTCTGCACTA
GATAATGGTCGATTTACGGTAGCTGCTGGTGCGGTTGGGCAAATTATGGCTTGTATTGAGGCGAGCGTAAAATATTGCCA
TGAGCGAGAAACATTCGGAAAAGAAATCGGTAAACACCAGTTAGTTCAACAAATGATCGCTAAAATGGAAGCCGGTTATC
AAATGAGTAAGCTACTTGTTTACCGCGCTGGCGAATTAAAGAATCAAGGAAAACGAAATACAAGAGAAACTTCTTTAGCA
AAATGGCAAGCATGTGATTTTGCTAATAAAGCAGCTGATGACGCTGTACAAATACATGGAGCTTATGGATACTCAGATGA
ATACCCAGTAGAAAGATTTTTACGTAATTCAAAGGCACCCGTTATATACGAAGGAACACGAGAAGTCCATACCATTATGC
AAGCGGAATACGTATTAGGTTATCGAGAAGATAAGCTGCTTAATCAAATGCTTCCAGCATGGGAGGAAACAAAATAG

Upstream 100 bases:

>100_bases
ACTGAAATTTTCCAGGACACCAATTACCTATCGTCACGCACCGCCTAACCCTGGAGAACATAACACCGATTATATACATT
TGAAAGGAGATTAGGAAATA

Downstream 100 bases:

>100_bases
TTTTAAAAAAAGGATACATTCTTAGCTTTTGACAATAGAAGTCGATTATGGTGGATGAAAATATCATTTCACGAACAAAA
GCGCAAACGCCCGTTTAGAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDFHFSEEQQLLRKTVRDFTDKEIMPYISEWDRNGKFDPTLLNKLAELGLMGVCIPEQYGGSGMDYNSLAIVCEELERGD
TAFRTAVSVHTGLNSMTLLQWGNEQQKQKYLIPQAKGEKIGAFGLTEPGAGSDVAALQSTAVKQGDHYILNGQKTWISLC
DIADHFIVFAYTKDRSEKHKGISAFIVERSWEGFSSKAIKGKHGIRSGNTGEIFFDHIKVPKENLLGKEGEGFKIAMSAL
DNGRFTVAAGAVGQIMACIEASVKYCHERETFGKEIGKHQLVQQMIAKMEAGYQMSKLLVYRAGELKNQGKRNTRETSLA
KWQACDFANKAADDAVQIHGAYGYSDEYPVERFLRNSKAPVIYEGTREVHTIMQAEYVLGYREDKLLNQMLPAWEETK

Sequences:

>Translated_398_residues
MDFHFSEEQQLLRKTVRDFTDKEIMPYISEWDRNGKFDPTLLNKLAELGLMGVCIPEQYGGSGMDYNSLAIVCEELERGD
TAFRTAVSVHTGLNSMTLLQWGNEQQKQKYLIPQAKGEKIGAFGLTEPGAGSDVAALQSTAVKQGDHYILNGQKTWISLC
DIADHFIVFAYTKDRSEKHKGISAFIVERSWEGFSSKAIKGKHGIRSGNTGEIFFDHIKVPKENLLGKEGEGFKIAMSAL
DNGRFTVAAGAVGQIMACIEASVKYCHERETFGKEIGKHQLVQQMIAKMEAGYQMSKLLVYRAGELKNQGKRNTRETSLA
KWQACDFANKAADDAVQIHGAYGYSDEYPVERFLRNSKAPVIYEGTREVHTIMQAEYVLGYREDKLLNQMLPAWEETK
>Mature_398_residues
MDFHFSEEQQLLRKTVRDFTDKEIMPYISEWDRNGKFDPTLLNKLAELGLMGVCIPEQYGGSGMDYNSLAIVCEELERGD
TAFRTAVSVHTGLNSMTLLQWGNEQQKQKYLIPQAKGEKIGAFGLTEPGAGSDVAALQSTAVKQGDHYILNGQKTWISLC
DIADHFIVFAYTKDRSEKHKGISAFIVERSWEGFSSKAIKGKHGIRSGNTGEIFFDHIKVPKENLLGKEGEGFKIAMSAL
DNGRFTVAAGAVGQIMACIEASVKYCHERETFGKEIGKHQLVQQMIAKMEAGYQMSKLLVYRAGELKNQGKRNTRETSLA
KWQACDFANKAADDAVQIHGAYGYSDEYPVERFLRNSKAPVIYEGTREVHTIMQAEYVLGYREDKLLNQMLPAWEETK

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=379, Percent_Identity=37.7308707124011, Blast_Score=272, Evalue=3e-73,
Organism=Homo sapiens, GI4557231, Length=385, Percent_Identity=38.961038961039, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI187960098, Length=385, Percent_Identity=38.961038961039, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=34.4919786096257, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI226958412, Length=372, Percent_Identity=37.0967741935484, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI226958414, Length=331, Percent_Identity=37.7643504531722, Blast_Score=229, Evalue=5e-60,
Organism=Homo sapiens, GI21361497, Length=346, Percent_Identity=38.150289017341, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=34.0425531914894, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=32.9842931937173, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4501857, Length=367, Percent_Identity=34.6049046321526, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4557235, Length=338, Percent_Identity=35.5029585798817, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI76496475, Length=339, Percent_Identity=35.9882005899705, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI7669494, Length=366, Percent_Identity=33.3333333333333, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI48976061, Length=341, Percent_Identity=29.6187683284457, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI211971008, Length=341, Percent_Identity=29.6187683284457, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI38505218, Length=395, Percent_Identity=28.3544303797468, Blast_Score=115, Evalue=7e-26,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=27.8215223097113, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87081958, Length=388, Percent_Identity=27.8350515463918, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI87082384, Length=279, Percent_Identity=26.5232974910394, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081702, Length=336, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=35.792349726776, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=38.1333333333333, Blast_Score=254, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI17508101, Length=367, Percent_Identity=37.0572207084469, Blast_Score=254, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=36.8146214099217, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=34.9081364829396, Blast_Score=244, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17538396, Length=373, Percent_Identity=34.0482573726542, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI71985184, Length=345, Percent_Identity=38.5507246376812, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=33.5958005249344, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=38.0952380952381, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=31.2154696132597, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71985192, Length=299, Percent_Identity=38.7959866220736, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=34.7985347985348, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=38.3620689655172, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=367, Percent_Identity=28.3378746594005, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=28.804347826087, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=28.5123966942149, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=333, Percent_Identity=29.1291291291291, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17531913, Length=175, Percent_Identity=24, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=26.7657992565056, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=26.7657992565056, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=42.3280423280423, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=41.0666666666667, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24660351, Length=373, Percent_Identity=39.9463806970509, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=36.3387978142077, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI21355753, Length=372, Percent_Identity=36.0215053763441, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI281363737, Length=346, Percent_Identity=34.971098265896, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI19920834, Length=387, Percent_Identity=33.5917312661499, Blast_Score=215, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 44653; Mature: 44653

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFHFSEEQQLLRKTVRDFTDKEIMPYISEWDRNGKFDPTLLNKLAELGLMGVCIPEQYG
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCHHCC
GSGMDYNSLAIVCEELERGDTAFRTAVSVHTGLNSMTLLQWGNEQQKQKYLIPQAKGEKI
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCCCC
GAFGLTEPGAGSDVAALQSTAVKQGDHYILNGQKTWISLCDIADHFIVFAYTKDRSEKHK
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEEEECCCCCHHC
GISAFIVERSWEGFSSKAIKGKHGIRSGNTGEIFFDHIKVPKENLLGKEGEGFKIAMSAL
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCEEEEEEEC
DNGRFTVAAGAVGQIMACIEASVKYCHERETFGKEIGKHQLVQQMIAKMEAGYQMSKLLV
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YRAGELKNQGKRNTRETSLAKWQACDFANKAADDAVQIHGAYGYSDEYPVERFLRNSKAP
HHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCCC
VIYEGTREVHTIMQAEYVLGYREDKLLNQMLPAWEETK
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFHFSEEQQLLRKTVRDFTDKEIMPYISEWDRNGKFDPTLLNKLAELGLMGVCIPEQYG
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCHHCC
GSGMDYNSLAIVCEELERGDTAFRTAVSVHTGLNSMTLLQWGNEQQKQKYLIPQAKGEKI
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCCCC
GAFGLTEPGAGSDVAALQSTAVKQGDHYILNGQKTWISLCDIADHFIVFAYTKDRSEKHK
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCEEEEEEECCCCCHHC
GISAFIVERSWEGFSSKAIKGKHGIRSGNTGEIFFDHIKVPKENLLGKEGEGFKIAMSAL
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCEEEEEEEC
DNGRFTVAAGAVGQIMACIEASVKYCHERETFGKEIGKHQLVQQMIAKMEAGYQMSKLLV
CCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YRAGELKNQGKRNTRETSLAKWQACDFANKAADDAVQIHGAYGYSDEYPVERFLRNSKAP
HHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCCC
VIYEGTREVHTIMQAEYVLGYREDKLLNQMLPAWEETK
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]