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The map label for this gene is corC [H]

Identifier: 23098105

GI number: 23098105

Start: 684911

End: 685786

Strand: Reverse

Name: corC [H]

Synonym: OB0650

Alternate gene names: 23098105

Gene position: 685786-684911 (Counterclockwise)

Preceding gene: 23098106

Following gene: 23098098

Centisome position: 18.89

GC content: 33.79

Gene sequence:

>876_bases
TTGACGATAGCGCTGATTAGTTTGTTTTTTCTTATTGTAGGCATAGTATGTTTTGTTGCTTGGAAAAAGGGTCTGCTGGT
AATCAATACAAGTGTGCTTAAAAATGCAAAGGAGCACCCATCAGTTGAGTCTGAAACAAACATCTATGAATTTAATGATA
AACATATTTCGGATATCGTTATTCATCGTATAGATATGTGTGTGCTTGAAGTAGATTCTTCTTATGAAGAAGTAATGGAT
GTGATTATAAACCAGCCTTACAACAGATATCCTGTAATTGAAGAAGATATCGATCAAATTATAGGAATTATCCACGTAAA
GGACGTACTTTCTTATTTACATAATTATAAAGATGCTACCAAGTTTCAGCTTCGAAATATCATGCATGATCCGTTCTTTA
TCTTAGAATCACAACGTGTAGACCTTGCGTTTAAAGATATGCAAAAAGAACAGATCACACTTGCAATTGTTTTAGATGAA
TATGGTGGAACTGAAGGACTTATTACAAGAGAAGATATGGTCAAAGAAATGGTTACTGATGTACTTCAAGAAGATGATAG
CTATGTATTGAATAAACCTTCCTTCATCCAACAACTGGCTGGAAATAGATACCGAATTCATGCTAATTCTCCACTGTACG
AATTAGAAGGTATACTAGGCATCACTTTCCCAGTAGAGGATTATGATACGTTAAGTGATTTTTTAATCGATCAATTAGGC
TATATCCCTGCCAATCATGAGAAGCCAAACCTACTTTATAAAAATATTCAATTTGAGATTACCGAAATATCTTCTCAAAA
AATACATTCAGCTATCGCAACCATTTATGAAGATGGAGTAACATTTATCGACCAATTTCATAGGCAACCTAGTTGA

Upstream 100 bases:

>100_bases
TCATTTATAATATTTACAGGTAAGTATATACTTGCCTGTTTTTATATATACAGCTTGTTTCGTTTGTTTGCTAATAATAA
ATCATGGAGGTCGTTAACTT

Downstream 100 bases:

>100_bases
ATCAAACTCATAATAAGAGTAAAAAACTCTCTTTATCCACAATGTTGGATTTAGAGAGTTTTTTTATAGCTTTTATTTAA
ATAGATAATCATTTTGTATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTIALISLFFLIVGIVCFVAWKKGLLVINTSVLKNAKEHPSVESETNIYEFNDKHISDIVIHRIDMCVLEVDSSYEEVMD
VIINQPYNRYPVIEEDIDQIIGIIHVKDVLSYLHNYKDATKFQLRNIMHDPFFILESQRVDLAFKDMQKEQITLAIVLDE
YGGTEGLITREDMVKEMVTDVLQEDDSYVLNKPSFIQQLAGNRYRIHANSPLYELEGILGITFPVEDYDTLSDFLIDQLG
YIPANHEKPNLLYKNIQFEITEISSQKIHSAIATIYEDGVTFIDQFHRQPS

Sequences:

>Translated_291_residues
MTIALISLFFLIVGIVCFVAWKKGLLVINTSVLKNAKEHPSVESETNIYEFNDKHISDIVIHRIDMCVLEVDSSYEEVMD
VIINQPYNRYPVIEEDIDQIIGIIHVKDVLSYLHNYKDATKFQLRNIMHDPFFILESQRVDLAFKDMQKEQITLAIVLDE
YGGTEGLITREDMVKEMVTDVLQEDDSYVLNKPSFIQQLAGNRYRIHANSPLYELEGILGITFPVEDYDTLSDFLIDQLG
YIPANHEKPNLLYKNIQFEITEISSQKIHSAIATIYEDGVTFIDQFHRQPS
>Mature_290_residues
TIALISLFFLIVGIVCFVAWKKGLLVINTSVLKNAKEHPSVESETNIYEFNDKHISDIVIHRIDMCVLEVDSSYEEVMDV
IINQPYNRYPVIEEDIDQIIGIIHVKDVLSYLHNYKDATKFQLRNIMHDPFFILESQRVDLAFKDMQKEQITLAIVLDEY
GGTEGLITREDMVKEMVTDVLQEDDSYVLNKPSFIQQLAGNRYRIHANSPLYELEGILGITFPVEDYDTLSDFLIDQLGY
IPANHEKPNLLYKNIQFEITEISSQKIHSAIATIYEDGVTFIDQFHRQPS

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=191, Percent_Identity=31.413612565445, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI1786879, Length=222, Percent_Identity=28.8288288288288, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33598; Mature: 33467

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIALISLFFLIVGIVCFVAWKKGLLVINTSVLKNAKEHPSVESETNIYEFNDKHISDIV
CHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCHHCCCCCCCCCEEECCCCHHHHHH
IHRIDMCVLEVDSSYEEVMDVIINQPYNRYPVIEEDIDQIIGIIHVKDVLSYLHNYKDAT
HHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
KFQLRNIMHDPFFILESQRVDLAFKDMQKEQITLAIVLDEYGGTEGLITREDMVKEMVTD
HHHHHHHCCCCEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCCCCCEEHHHHHHHHHHH
VLQEDDSYVLNKPSFIQQLAGNRYRIHANSPLYELEGILGITFPVEDYDTLSDFLIDQLG
HHHCCCCEEECCCHHHHHHCCCEEEEECCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHC
YIPANHEKPNLLYKNIQFEITEISSQKIHSAIATIYEDGVTFIDQFHRQPS
CCCCCCCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure 
TIALISLFFLIVGIVCFVAWKKGLLVINTSVLKNAKEHPSVESETNIYEFNDKHISDIV
HHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCHHCCCCCCCCCEEECCCCHHHHHH
IHRIDMCVLEVDSSYEEVMDVIINQPYNRYPVIEEDIDQIIGIIHVKDVLSYLHNYKDAT
HHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
KFQLRNIMHDPFFILESQRVDLAFKDMQKEQITLAIVLDEYGGTEGLITREDMVKEMVTD
HHHHHHHCCCCEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCCCCCEEHHHHHHHHHHH
VLQEDDSYVLNKPSFIQQLAGNRYRIHANSPLYELEGILGITFPVEDYDTLSDFLIDQLG
HHHCCCCEEECCCHHHHHHCCCEEEEECCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHC
YIPANHEKPNLLYKNIQFEITEISSQKIHSAIATIYEDGVTFIDQFHRQPS
CCCCCCCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]