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The map label for this gene is rsbS [H]

Identifier: 23098080

GI number: 23098080

Start: 653117

End: 653473

Strand: Direct

Name: rsbS [H]

Synonym: OB0625

Alternate gene names: 23098080

Gene position: 653117-653473 (Clockwise)

Preceding gene: 23098079

Following gene: 23098081

Centisome position: 17.99

GC content: 35.01

Gene sequence:

>357_bases
ATGCGCATTCCAATTTTAAAGCTTCATAACTACTTACTTATCTCTATTCAAACAGAAATAGACGACCAAACAGCAATTCA
ATTTCAAGAGGATTTATTAGATAAAATCCATAAAACAGGAGCATCAGGAGTAGTAATTGATCTTACCTCTGTTGATATAA
TAGATTCGTTTATAGCGAAGGTGCTTGGAGACGTTGTATCAATGTCGGATTTAATGGGGGCGAAAGTTGTACTTACTGGT
ATTCAACCTGCTGTTGCAATGACTTTAATTGATTTAGGTATCCATATGCAAAATGTCCCAACAGCATTAGATTTAGAACA
AGGATTAGTTAAGCTTCAACAGGAACTGGAGGTATAA

Upstream 100 bases:

>100_bases
ACGAAAGCATTAGAACTTACTGGACGTGAGGTTATAGATTTAAAAAATCGCGAGTCTGATATTGAAGGAATCATAAATTC
CTTGAAAGGAGAATAAGTAT

Downstream 100 bases:

>100_bases
TGATGGATCCACAATCCTGCGTGAATATAAAAAAAGAGTGGGATATTGTTGGGGCAAGACAACTTGGTCGTGAGATGGCA
AAGCAAGTAGGTTTCGGAAC

Product: negative regulator of sigma-B activity

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MRIPILKLHNYLLISIQTEIDDQTAIQFQEDLLDKIHKTGASGVVIDLTSVDIIDSFIAKVLGDVVSMSDLMGAKVVLTG
IQPAVAMTLIDLGIHMQNVPTALDLEQGLVKLQQELEV

Sequences:

>Translated_118_residues
MRIPILKLHNYLLISIQTEIDDQTAIQFQEDLLDKIHKTGASGVVIDLTSVDIIDSFIAKVLGDVVSMSDLMGAKVVLTG
IQPAVAMTLIDLGIHMQNVPTALDLEQGLVKLQQELEV
>Mature_118_residues
MRIPILKLHNYLLISIQTEIDDQTAIQFQEDLLDKIHKTGASGVVIDLTSVDIIDSFIAKVLGDVVSMSDLMGAKVVLTG
IQPAVAMTLIDLGIHMQNVPTALDLEQGLVKLQQELEV

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 12877; Mature: 12877

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPILKLHNYLLISIQTEIDDQTAIQFQEDLLDKIHKTGASGVVIDLTSVDIIDSFIAK
CCCCCEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
VLGDVVSMSDLMGAKVVLTGIQPAVAMTLIDLGIHMQNVPTALDLEQGLVKLQQELEV
HHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIPILKLHNYLLISIQTEIDDQTAIQFQEDLLDKIHKTGASGVVIDLTSVDIIDSFIAK
CCCCCEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
VLGDVVSMSDLMGAKVVLTGIQPAVAMTLIDLGIHMQNVPTALDLEQGLVKLQQELEV
HHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]