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The map label for this gene is dmsD [H]

Identifier: 22124778

GI number: 22124778

Start: 972530

End: 973240

Strand: Direct

Name: dmsD [H]

Synonym: y0867

Alternate gene names: 22124778

Gene position: 972530-973240 (Clockwise)

Preceding gene: 22124777

Following gene: 22124782

Centisome position: 21.14

GC content: 48.52

Gene sequence:

>711_bases
ATGATTAAAACAGATATGACTTATCAAGACATTGTTTATAAAGATACTGTTTATCAAGACAGTGTTTATCAAAAAATCGG
ACTAACGGGGCGAGTGCTAGGTGCGCTTTTTTATTGTGAGCCGGATAGCGCGGAGTGCCGCGATATTGTGGTGCAATTGC
GTAATGGCACGTGGGCCGCTGAATGGCCTTATGGTGGTGCAGACGAACTAATGCCGATTGCGACATTATTGGCGGCAGCT
CAATCAGATCAGTATCAATCCATTGCTCATCAATCAGCGGCAGCCCCATTAGCAGAAACATTGGAAGAGGCTTGGCAGCG
GCTGTTTATTGGTCCATATGCCTTGCCAGCGCCGCCTTGGGGCTCCGTTTATCTGGATAAAGACATGGTGCTGTTTGGCG
ACTCCACACTAAAACTGCGTAACTGGATGCAGCAGCGGCATGTTGAAGTCACATTGAAACAGCAGGAGCCTGAAGATCAT
TTCGGTTTATTGATGATGATGGCGGCCTGGTTGGCAGAACATCAGCCGGTCGATCTCCCGGTTTTGTTAGCTGATCACTT
ATTACCCTGGAGTTATCGTTATCTGGCGTTGTTGCAATCCGATGCAGGCCACCCGTTTTATCAAGGGTTGGCACAGTTGA
CCACCCTGACCTTGGCCCATTGGCAACATGAATTGCAAGTGACACCGGCTGGGGTTGAGTTATATCGCTAA

Upstream 100 bases:

>100_bases
AATAGCTTTGCTCTGCCTCATGGCGTGCTAAAACCACGGTCATACAGGGCTGAACAACATGATCATAACAATATGGTCGT
AAGAAAATGGTCGTAAGAAA

Downstream 100 bases:

>100_bases
ATCTGAACTTATTTATTTCAACCTGAACTTATTTATGTGATAACCCGCGTGATTTTTTACCGATATTACCGGTCAGGCTA
ATCAGTGAATCAAGGGGGAG

Product: twin-argninine leader-binding protein DmsD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MIKTDMTYQDIVYKDTVYQDSVYQKIGLTGRVLGALFYCEPDSAECRDIVVQLRNGTWAAEWPYGGADELMPIATLLAAA
QSDQYQSIAHQSAAAPLAETLEEAWQRLFIGPYALPAPPWGSVYLDKDMVLFGDSTLKLRNWMQQRHVEVTLKQQEPEDH
FGLLMMMAAWLAEHQPVDLPVLLADHLLPWSYRYLALLQSDAGHPFYQGLAQLTTLTLAHWQHELQVTPAGVELYR

Sequences:

>Translated_236_residues
MIKTDMTYQDIVYKDTVYQDSVYQKIGLTGRVLGALFYCEPDSAECRDIVVQLRNGTWAAEWPYGGADELMPIATLLAAA
QSDQYQSIAHQSAAAPLAETLEEAWQRLFIGPYALPAPPWGSVYLDKDMVLFGDSTLKLRNWMQQRHVEVTLKQQEPEDH
FGLLMMMAAWLAEHQPVDLPVLLADHLLPWSYRYLALLQSDAGHPFYQGLAQLTTLTLAHWQHELQVTPAGVELYR
>Mature_236_residues
MIKTDMTYQDIVYKDTVYQDSVYQKIGLTGRVLGALFYCEPDSAECRDIVVQLRNGTWAAEWPYGGADELMPIATLLAAA
QSDQYQSIAHQSAAAPLAETLEEAWQRLFIGPYALPAPPWGSVYLDKDMVLFGDSTLKLRNWMQQRHVEVTLKQQEPEDH
FGLLMMMAAWLAEHQPVDLPVLLADHLLPWSYRYLALLQSDAGHPFYQGLAQLTTLTLAHWQHELQVTPAGVELYR

Specific function: Binds to the twin-arginine signal peptide of dmsA and torA. Could be required for the biogenesis of DMSO reductase rather than for the targeting of dmsA to the inner membrane [H]

COG id: COG3381

COG function: function code R; Uncharacterized component of anaerobic dehydrogenases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Cytoplasm (By similarity). Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the torD/dmsD family. DmsD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081942, Length=213, Percent_Identity=46.4788732394366, Blast_Score=186, Evalue=9e-49,
Organism=Escherichia coli, GI1787272, Length=207, Percent_Identity=27.0531400966184, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020945 [H]

Pfam domain/function: PF02613 Nitrate_red_del [H]

EC number: NA

Molecular weight: Translated: 26766; Mature: 26766

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTDMTYQDIVYKDTVYQDSVYQKIGLTGRVLGALFYCEPDSAECRDIVVQLRNGTWAA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCHHHHHHHHHCCCCEEE
EWPYGGADELMPIATLLAAAQSDQYQSIAHQSAAAPLAETLEEAWQRLFIGPYALPAPPW
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
GSVYLDKDMVLFGDSTLKLRNWMQQRHVEVTLKQQEPEDHFGLLMMMAAWLAEHQPVDLP
CCEEECCCEEEECCCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCH
VLLADHLLPWSYRYLALLQSDAGHPFYQGLAQLTTLTLAHWQHELQVTPAGVELYR
HHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEECC
>Mature Secondary Structure
MIKTDMTYQDIVYKDTVYQDSVYQKIGLTGRVLGALFYCEPDSAECRDIVVQLRNGTWAA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCHHHHHHHHHCCCCEEE
EWPYGGADELMPIATLLAAAQSDQYQSIAHQSAAAPLAETLEEAWQRLFIGPYALPAPPW
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
GSVYLDKDMVLFGDSTLKLRNWMQQRHVEVTLKQQEPEDHFGLLMMMAAWLAEHQPVDLP
CCEEECCCEEEECCCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCH
VLLADHLLPWSYRYLALLQSDAGHPFYQGLAQLTTLTLAHWQHELQVTPAGVELYR
HHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]