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The map label for this gene is dmsC [H]

Identifier: 22124777

GI number: 22124777

Start: 971461

End: 972384

Strand: Direct

Name: dmsC [H]

Synonym: y0866

Alternate gene names: 22124777

Gene position: 971461-972384 (Clockwise)

Preceding gene: 22124776

Following gene: 22124778

Centisome position: 21.12

GC content: 54.0

Gene sequence:

>924_bases
ATGCCAACAGCCGCCCGGTCAGAGATACCACCGGTCATCTGGCAAACCCGAAGGAGGTATAACATGGGCTCAGGATGGCA
TGAATGGCCACTAATGGTCTTTACCGTACTGGGGCAGTGTGTGGTCGGGGGCTTTATTGTTCTCGGTCTGGCACTGATAT
TCGGTGGTTTGAGTCGCGGGCAACAACAGCGGGTTCACCGCAGCATGTTTGTGCTTTGGGTGCTGATGGCACTGGCTTTT
ATCGCCTCTACACTGCATTTAGGTTCGCCAATGCGGGCGTTCAACTCATTGAATCGGATCGGTGAATCTGCACTGAGTAA
TGAGATTGCCGCCGGTTCGTTGTTCTTTGCTGTAGCCGGTTTTTACTGGTTGTTGGCGGTGTTGGATAAAATGCCTGCCG
CGCTTGGTAAGATCTGGCTGGTGGTGGCAATGGTGTTGGGCGTGATCTTTGTCTACGCCATGTGCCGGGTCTACTCCATT
AATACGGTACCGACGTGGGACAGTATTTATACCCCGCTGGGCTTTGTCCTGACCACGTTGATCGGTGGCCCGCTATTGGG
TTATCTGTTGCTGCAATTGGCTGATGTTAATGGGCGGGCGATGTTACAACTGCCGATGATCAGCGTATTGGCACTGATCA
TCAGTGTGGCCAGTGTCATTATGCAGGCGGCCAGTTTGCCGCTGATTTATAGCTCGGTACAGCAAGCTTCAGCGCTGATC
CCCGACTATGGCTCATTGATGGTATGGCGGTTAGTGCTGCTGGTGTTGGGGCTTGGCTGCTGGATTTGCCCGTTGATCAG
AGGCCGTCGCCCGATGACGCTGGTGATGGTCTTGGGCACGTTACTGGTTATTGCCGGTGAGTTGATTGGCCGTGGGGTGT
TCTACGGGTTACATATGACGGTCGGTATGGCGGTTGGGGGCTAA

Upstream 100 bases:

>100_bases
GCCCCTATCGATGAATTACGCGAAAAATACGGTGATTTAGCTGAAATTGCGCCTCTGCCTGCCGCTCACTTCACGCTGCC
GAATATCGTACTAAAACCTA

Downstream 100 bases:

>100_bases
TCTCCAGACGGCGGTGACACTTTGGCTATTCTGGGGAGCGCCCAGAATAGCTTTGCTCTGCCTCATGGCGTGCTAAAACC
ACGGTCATACAGGGCTGAAC

Product: anaerobic dimethyl sulfoxide reductase chain C

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MPTAARSEIPPVIWQTRRRYNMGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAF
IASTLHLGSPMRAFNSLNRIGESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSI
NTVPTWDSIYTPLGFVLTTLIGGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALI
PDYGSLMVWRLVLLVLGLGCWICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG

Sequences:

>Translated_307_residues
MPTAARSEIPPVIWQTRRRYNMGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAF
IASTLHLGSPMRAFNSLNRIGESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSI
NTVPTWDSIYTPLGFVLTTLIGGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALI
PDYGSLMVWRLVLLVLGLGCWICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG
>Mature_306_residues
PTAARSEIPPVIWQTRRRYNMGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFI
ASTLHLGSPMRAFNSLNRIGESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSIN
TVPTWDSIYTPLGFVLTTLIGGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIP
DYGSLMVWRLVLLVLGLGCWICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=285, Percent_Identity=66.6666666666667, Blast_Score=333, Evalue=6e-93,
Organism=Escherichia coli, GI1787873, Length=286, Percent_Identity=59.7902097902098, Blast_Score=315, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 33313; Mature: 33182

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAARSEIPPVIWQTRRRYNMGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRG
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIGESALSNEIAAGSLFFAVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYWLLAVLDKMPAALGKIWLVVAMVLGVIFVYAMCRVYSINTVPTWDSIYTPLGFVLTTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IGGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
PDYGSLMVWRLVLLVLGLGCWICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGMAVGG
HHHHCCC
>Mature Secondary Structure 
PTAARSEIPPVIWQTRRRYNMGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRG
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH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HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]