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The map label for this gene is trpG [H]

Identifier: 21911249

GI number: 21911249

Start: 1729388

End: 1729954

Strand: Direct

Name: trpG [H]

Synonym: SpyM3_1713

Alternate gene names: 21911249

Gene position: 1729388-1729954 (Clockwise)

Preceding gene: 21911248

Following gene: 21911250

Centisome position: 91.0

GC content: 45.5

Gene sequence:

>567_bases
ATGATACTCTTAATTGATAATTACGATTCATTTACCTACAACCTCGCCCAATATTTAAGTGAATTTGACGAGACGATTGT
CTTGTATAACCAAGACCCAAACTTATATGACATGGCCAAAAAGGCCGACGCGCTAGTCCTCTCACCTGGTCCTGGTTGGC
CCAAGGAAGCCAACCAAATGCCAAAACTCATTCAAGACTTTTACCAAACAAAACCTATCTTAGGAGTGTGTCTGGGACAC
CAAGCTATCGCTGAAACATTAGGGGGAACCTTACGCTTGGCCAAACGCGTCATGCATGGGAGACAAAGCACCATTGAAAC
GCAAGGCCCTGCTAGTCTTTTTGGCTCCCTGCCACAAGAGATCACCGTCATGCGTTACCATTCCATCGTTGTGGATCAGT
TACCAAAAGGTTTTAGCGTAACTGCTAGAGACTGTGACGATCAAGAAATCATGGCCTTTGAACACCACACCCTGCCACTT
TTTGGGCTACAATTTCACCCAGAAAGCATCGGAACTCCTGATGGCATGACTATGATTGCTAACTTCATCGCAGCTATTCC
CCGTTAA

Upstream 100 bases:

>100_bases
GTGGCCTCTATCCTCTCAACCTTGAGCTTACTCACCTTGATGCCCTCTTAACTAAGAGTCAAGCCTAAACTGCCACTCAT
CTTTTGTTATTAAGGAACCT

Downstream 100 bases:

>100_bases
TCCCATCCCCCAAAAGAAAGGAGGACAGTTACATGCCTGATCACTTAGCGCTCAGAATGCGCCCCAAAACCATTTCAGAG
GTCATCGGACAAAAACACCT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADALVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGH
QAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFGSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
FGLQFHPESIGTPDGMTMIANFIAAIPR

Sequences:

>Translated_188_residues
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADALVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGH
QAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFGSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
FGLQFHPESIGTPDGMTMIANFIAAIPR
>Mature_188_residues
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADALVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGH
QAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFGSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
FGLQFHPESIGTPDGMTMIANFIAAIPR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=145, Percent_Identity=31.7241379310345, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=46.524064171123, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=41.4893617021277, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=36.5079365079365, Blast_Score=120, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323873, Length=182, Percent_Identity=25.2747252747253, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20986; Mature: 20986

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADALVLSPGPGWPKEANQM
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCEEEECCCCCCCHHHHHH
PKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFGSLPQE
HHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCHH
ITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPLFGLQFHPESIGTPDGMTMIA
HHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHH
NFIAAIPR
HHHHHCCC
>Mature Secondary Structure
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADALVLSPGPGWPKEANQM
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCEEEECCCCCCCHHHHHH
PKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFGSLPQE
HHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCHH
ITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPLFGLQFHPESIGTPDGMTMIA
HHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHH
NFIAAIPR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]