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The map label for this gene is pabP [H]

Identifier: 21911248

GI number: 21911248

Start: 1727670

End: 1729355

Strand: Direct

Name: pabP [H]

Synonym: SpyM3_1712

Alternate gene names: 21911248

Gene position: 1727670-1729355 (Clockwise)

Preceding gene: 21911242

Following gene: 21911249

Centisome position: 90.91

GC content: 44.6

Gene sequence:

>1686_bases
TTGGTAGCCAAGTCCTTAGATCAGGTCGGTCCAGTCATTGAAAACGTACAACACTACCAACAGCTGGGCTATTACGTGGT
GGGCTATCTCAGTTACGAAGCAACTGCTTTTTTTGACAATGCCTTACAAACCCATAATGACAGACTAGGCAACGAGTACC
TTGCCTATTTTACGGTGCACAAAACCTGTCAAAAAAAAGACCTACCTCTTGATTATGACAGCATTACTATCCCTAACCAA
TGGGTCAGCCTCACTCAAAAAGAAGCCTATCAAAAAGCCATTGAAACCATTCACCATGAGATGCGACAGGGCAATACTTA
TCAGGTCAACTATACCCTTCAATTAACTCAGGAACTCAATGCAGCTGACAGCTTAGCCATTTACAATAAACTCGTCATTG
AACAGGCCGCTGGCTACAATGCCTATATCGCCCATGATGACTTTGCTGTTATTTCGGCTAGTCCTGAGTTGTTCTTTAAA
CAAGAGGGCAACAGGTTAACTACAAGACCTATGAAGGGTACCACCAAGCGTGGGGTTAATAGCTGGCTGGATCAACAAGA
ACATGACTGGCTCCAAACTGATGGGAAAAATCGCTCTGAAAACATGATGATTGTGGATTTGCTCCGCAATGACATGGGGA
AAATTTGCCAAACAGGCAGTGTTTGTGTCGATAGGCTCTGTGAGGTCGAGCGATACTCTACCGTCTGGCAAATGACCTCA
ACTATTGTTGGTGACCTCAAAGCGGACTGTGACCTGATAGACATTCTCACAGCTCTCTTTCCTTGTGGCTCTATCACGGG
GGCTCCTAAAGTCTCCACCATGGCAATTATCACATCTCTGGAGCCAAAACCAAGGGGGATTTATTGTGGAAGTATTGGCA
TTTGCCTACCTGATGGTCGCCGTTTCTTCAATGTTCCCATTAGAACCATCCAGCTCAGTCATAATCAAGCTACTTATGGT
GTCGGAGGCGGTATCACTTGGCAAAGCAAGTGGGAAGACGAATACGAAGAAGTCCAGCAAAAAACAACTTTTCTCTATCG
GCACAAACAAATCTTTGACCTCAAAACAACCGCCAAGGTGGAACACCAAAAAATAGCCTTCCTTGAGCAACACCTCAATC
GCCTTAAAGAAGCAGCCACTTATTTTGCTTACCCTTATAATGAAAAAGCTTTGCAGAAACAACTAGCAACCTATTTGGAA
AATAAGGATAATGCTGCCTACCGCTTGATGATTCGTTTATCCAAAGATGGAAAGATTAGCCTCTCTGATCAACCTTTGGA
GCCTTTATCAGCCGATTTTCTGACAGCTCAACTCTCCTTACAGGACAAGGACGTGACAGCTTCGCCTTTTACCTACTTTA
AGACCAGCTACCGGCCTCATATTGAGCAAAAATCTTATGAACAGCTATTCTATAACCAAGCGGGGCAATTATTGGAAACG
TCCATTGGCAATCTCTTTGTTCAGCTGGGTCAGACCCTCTACACACCACCAGTGGCTGTGGGGATTTTACCAGGACTTTT
TCGCCAAGAACTGCTAGCTACTGGTCAAGCTCAGGAAAAAGAGGTGACACTAGCTGATTTAAAAGAGGCTAGCGCTATTT
TTGGAGGAAATGCTGTCCGTGGCCTCTATCCTCTCAACCTTGAGCTTACTCACCTTGATGCCCTCTTAACTAAGAGTCAA
GCCTAA

Upstream 100 bases:

>100_bases
GCAACCGCTTTTATGATATAATTTGGGTATGCATAGAAAAACGATTATTGATTTCAAAGAGCTCGGGCAACGCTATCTTT
TTGATGAGCCATTAGTAGAA

Downstream 100 bases:

>100_bases
ACTGCCACTCATCTTTTGTTATTAAGGAACCTATGATACTCTTAATTGATAATTACGATTCATTTACCTACAACCTCGCC
CAATATTTAAGTGAATTTGA

Product: putative para-aminobenzoate synthetase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MVAKSLDQVGPVIENVQHYQQLGYYVVGYLSYEATAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIPNQ
WVSLTQKEAYQKAIETIHHEMRQGNTYQVNYTLQLTQELNAADSLAIYNKLVIEQAAGYNAYIAHDDFAVISASPELFFK
QEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQTDGKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTS
TIVGDLKADCDLIDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYG
VGGGITWQSKWEDEYEEVQQKTTFLYRHKQIFDLKTTAKVEHQKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLATYLE
NKDNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQDKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLET
SIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGLYPLNLELTHLDALLTKSQ
A

Sequences:

>Translated_561_residues
MVAKSLDQVGPVIENVQHYQQLGYYVVGYLSYEATAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIPNQ
WVSLTQKEAYQKAIETIHHEMRQGNTYQVNYTLQLTQELNAADSLAIYNKLVIEQAAGYNAYIAHDDFAVISASPELFFK
QEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQTDGKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTS
TIVGDLKADCDLIDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYG
VGGGITWQSKWEDEYEEVQQKTTFLYRHKQIFDLKTTAKVEHQKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLATYLE
NKDNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQDKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLET
SIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGLYPLNLELTHLDALLTKSQ
A
>Mature_561_residues
MVAKSLDQVGPVIENVQHYQQLGYYVVGYLSYEATAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIPNQ
WVSLTQKEAYQKAIETIHHEMRQGNTYQVNYTLQLTQELNAADSLAIYNKLVIEQAAGYNAYIAHDDFAVISASPELFFK
QEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQTDGKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTS
TIVGDLKADCDLIDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYG
VGGGITWQSKWEDEYEEVQQKTTFLYRHKQIFDLKTTAKVEHQKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLATYLE
NKDNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQDKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLET
SIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGLYPLNLELTHLDALLTKSQ
A

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=310, Percent_Identity=34.1935483870968, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787518, Length=282, Percent_Identity=29.4326241134752, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=24.3243243243243, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082077, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=257, Percent_Identity=34.2412451361868, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=317, Percent_Identity=29.0220820189274, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 63459; Mature: 63459

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKSLDQVGPVIENVQHYQQLGYYVVGYLSYEATAFFDNALQTHNDRLGNEYLAYFTVH
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCHHCCCCEEEEEEEH
KTCQKKDLPLDYDSITIPNQWVSLTQKEAYQKAIETIHHEMRQGNTYQVNYTLQLTQELN
HHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCC
AADSLAIYNKLVIEQAAGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVN
CHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCEEEECCCCEEECCCCCCCHHHHHH
SWLDQQEHDWLQTDGKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTS
HHHCHHHCCHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TIVGDLKADCDLIDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGR
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCEEEECCCCC
RFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYEEVQQKTTFLYRHKQIFDLKTTAKV
EEEECCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECHHHHHH
EHQKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLATYLENKDNAAYRLMIRLSKDGKIS
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEE
LSDQPLEPLSADFLTAQLSLQDKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLET
ECCCCCCCCCHHHEEEEEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
SIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
GLYPLNLELTHLDALLTKSQA
CEEECCEEEHHHHHHHHCCCC
>Mature Secondary Structure
MVAKSLDQVGPVIENVQHYQQLGYYVVGYLSYEATAFFDNALQTHNDRLGNEYLAYFTVH
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCHHCCCCEEEEEEEH
KTCQKKDLPLDYDSITIPNQWVSLTQKEAYQKAIETIHHEMRQGNTYQVNYTLQLTQELN
HHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCC
AADSLAIYNKLVIEQAAGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVN
CHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCEEEECCCCEEECCCCCCCHHHHHH
SWLDQQEHDWLQTDGKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTS
HHHCHHHCCHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TIVGDLKADCDLIDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGR
HHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCEEEECCCCC
RFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYEEVQQKTTFLYRHKQIFDLKTTAKV
EEEECCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECHHHHHH
EHQKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLATYLENKDNAAYRLMIRLSKDGKIS
HHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEE
LSDQPLEPLSADFLTAQLSLQDKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLET
ECCCCCCCCCHHHEEEEEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
SIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
GLYPLNLELTHLDALLTKSQA
CEEECCEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]