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The map label for this gene is acpS

Identifier: 21672528

GI number: 21672528

Start: 282784

End: 283164

Strand: Reverse

Name: acpS

Synonym: BUsg247

Alternate gene names: 21672528

Gene position: 283164-282784 (Counterclockwise)

Preceding gene: 21672529

Following gene: 21672525

Centisome position: 44.14

GC content: 23.36

Gene sequence:

>381_bases
ATGTCTATTATTGGTATAGGAACAGATATTATAGAAATTTTTCGTATTAAAAATATTGTTTACAATTTTAAAGATAAATT
AGCTGAAAGAATTTTATCAGTGCAAGAATTGGAAAAATATAAAGTCAATAAAAACCCCATAAAATTTCTTGCTAAAAGAT
TTGCAGTTAAAGAAGCAGCTTCTAAAGCTTTAGGAACAGGGATAAGTTATGGAATAAAATTTAATCAAATAGAATTATAT
AATAATAATTTAGGTAAACCAAAATTACGTTTTTTAAAATATGCTTTACAAAAATCTGAAGAGATGAAATGTAAATCTAT
ATTTGTCAGTATATCTGATGAGAAATTGTACGCATGTGCATTAGTTATTTTAGAAAAATAA

Upstream 100 bases:

>100_bases
AAAATAGTTTTTAAAATTAGTTAAAATACTTAAAAATTTTAACTAATTTTAAAAATCAAACTAAACATTTTACTAAAACA
AAGGAAATTTTACTACTAAA

Downstream 100 bases:

>100_bases
TTATTTTTAAGAAAAAGGGTATAAATTAAAATCTTTTATTTTTAAAAAAATTGCTTAATATCTTAGCACATTCATTTCTC
ATTATGTGTTTTTTTATTTT

Product: holo-[acyl-carrier protein] synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MSIIGIGTDIIEIFRIKNIVYNFKDKLAERILSVQELEKYKVNKNPIKFLAKRFAVKEAASKALGTGISYGIKFNQIELY
NNNLGKPKLRFLKYALQKSEEMKCKSIFVSISDEKLYACALVILEK

Sequences:

>Translated_126_residues
MSIIGIGTDIIEIFRIKNIVYNFKDKLAERILSVQELEKYKVNKNPIKFLAKRFAVKEAASKALGTGISYGIKFNQIELY
NNNLGKPKLRFLKYALQKSEEMKCKSIFVSISDEKLYACALVILEK
>Mature_125_residues
SIIGIGTDIIEIFRIKNIVYNFKDKLAERILSVQELEKYKVNKNPIKFLAKRFAVKEAASKALGTGISYGIKFNQIELYN
NNLGKPKLRFLKYALQKSEEMKCKSIFVSISDEKLYACALVILEK

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=50.4, Blast_Score=142, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BUCAP (Q8K9R3)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660595.1
- ProteinModelPortal:   Q8K9R3
- SMR:   Q8K9R3
- EnsemblBacteria:   EBBUCT00000000186
- GeneID:   1005449
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg247
- GeneTree:   EBGT00050000008114
- HOGENOM:   HBG734479
- OMA:   DYAIAFI
- ProtClustDB:   CLSK315829
- BioCyc:   BAPH198804:BUSG247-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14441; Mature: 14310

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIGIGTDIIEIFRIKNIVYNFKDKLAERILSVQELEKYKVNKNPIKFLAKRFAVKEAA
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SKALGTGISYGIKFNQIELYNNNLGKPKLRFLKYALQKSEEMKCKSIFVSISDEKLYACA
HHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEHHEEEEECCCHHHHHH
LVILEK
EEEECC
>Mature Secondary Structure 
SIIGIGTDIIEIFRIKNIVYNFKDKLAERILSVQELEKYKVNKNPIKFLAKRFAVKEAA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SKALGTGISYGIKFNQIELYNNNLGKPKLRFLKYALQKSEEMKCKSIFVSISDEKLYACA
HHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEHHEEEEECCCHHHHHH
LVILEK
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438