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The map label for this gene is aroC

Identifier: 21672382

GI number: 21672382

Start: 102466

End: 103527

Strand: Reverse

Name: aroC

Synonym: BUsg090

Alternate gene names: 21672382

Gene position: 103527-102466 (Counterclockwise)

Preceding gene: 21672395

Following gene: 21672380

Centisome position: 16.14

GC content: 33.99

Gene sequence:

>1062_bases
ATGGCTGGAAATACAATTGGAAAAGTTTTTCGTGTAACTACTTTCGGTGAATCTCATGGAACAGCACTAGGATGTGTAAT
TGATGGAATGCCACCAGGTTTAGAATTATCTTCAGATGATTTGCAATATGATTTAAATCGTAGAAGACCTGGAACTTCAC
GTTATACTACTCAACGATCTGAATTAGATGAAGTTCAAATACTTTCAGGAGTATTTAAAGGAACAACTACAGGAACAAGT
ATTGGTTTAGTTATTCAAAATAAAGACCAACGTTCACAAGATTATAGCGAAATAAAAGACTTATTTAGACCCGGACATGC
TGATTATACTTACGAAAAAAAATATGGAATACGAGACTATCGTGGTGGTGGAAGATCTTCAGCTCGTGAAACTGCAATGC
GAGTTGCCGCAGGTAGTATTGCAAAAAAATACCTTAAAATTCAAACTGGAATAGTTATTCGTGCATATTTATCAGCAATG
GGAGATATAAAATGTCCATTTGAATCATGGGAAGAAGTAGAACAAAATCCTTTTTTTTGTTCAAATAAAAACAAAGTCTT
TCAGTTAGAAGAACTAATTAAAAAATTAAAAAAAACAGGTGATTCAATAGGAGCAGAAATCACAATTATAGCCCAAAACG
TACCAGTAGGTTTCGGAGAACCAGTTTTTGATAGACTAGATGCAGATTTAGCTCATGCTTTGATGAGTATCAATGCTGCA
AAAGGAGTAGAAATTGGAGATGGTTTTTCAGTAGTTAACCAAAAGGGGAGCGAAAATAGAGATGAAATGACTCCTAATGG
ATTTAAAAGTAATCATTGCGGGGGTATTTTAGGAGGGATTAGCAATGGTGAAAATATTTTCTTAAAAGTTGCATTCAAAC
CTACTTCAAGTATTCGACAATCAGGAAATACAATAAATAAAAACAATGAAAAAGTCAAAATAGTAATCAAAGGAAGACAT
GATCCATGCGTAGGAATACGTGCTGTACCAATAGCGGAAGCAATGGTAGCAATAGTACTAATGGATCATCTATTAAGATT
TAGAGCACAATGTGCAAAATAA

Upstream 100 bases:

>100_bases
AAATTTATCATTAAATATTTTTTTAGATAAAAAAATTATTTTTTTTATTTTTTTTTCTGTATAGTTATATCATTTAAATC
AAAATTTAATAGAAAAAAAA

Downstream 100 bases:

>100_bases
CTTTTATAATTAAAAAAAATTAAATATTTTTGCTACTAAATTTATTATTTAGTAGCTTAGAGGAATATAAAAACTTAATA
ACATTATATTTATTCACTAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MAGNTIGKVFRVTTFGESHGTALGCVIDGMPPGLELSSDDLQYDLNRRRPGTSRYTTQRSELDEVQILSGVFKGTTTGTS
IGLVIQNKDQRSQDYSEIKDLFRPGHADYTYEKKYGIRDYRGGGRSSARETAMRVAAGSIAKKYLKIQTGIVIRAYLSAM
GDIKCPFESWEEVEQNPFFCSNKNKVFQLEELIKKLKKTGDSIGAEITIIAQNVPVGFGEPVFDRLDADLAHALMSINAA
KGVEIGDGFSVVNQKGSENRDEMTPNGFKSNHCGGILGGISNGENIFLKVAFKPTSSIRQSGNTINKNNEKVKIVIKGRH
DPCVGIRAVPIAEAMVAIVLMDHLLRFRAQCAK

Sequences:

>Translated_353_residues
MAGNTIGKVFRVTTFGESHGTALGCVIDGMPPGLELSSDDLQYDLNRRRPGTSRYTTQRSELDEVQILSGVFKGTTTGTS
IGLVIQNKDQRSQDYSEIKDLFRPGHADYTYEKKYGIRDYRGGGRSSARETAMRVAAGSIAKKYLKIQTGIVIRAYLSAM
GDIKCPFESWEEVEQNPFFCSNKNKVFQLEELIKKLKKTGDSIGAEITIIAQNVPVGFGEPVFDRLDADLAHALMSINAA
KGVEIGDGFSVVNQKGSENRDEMTPNGFKSNHCGGILGGISNGENIFLKVAFKPTSSIRQSGNTINKNNEKVKIVIKGRH
DPCVGIRAVPIAEAMVAIVLMDHLLRFRAQCAK
>Mature_352_residues
AGNTIGKVFRVTTFGESHGTALGCVIDGMPPGLELSSDDLQYDLNRRRPGTSRYTTQRSELDEVQILSGVFKGTTTGTSI
GLVIQNKDQRSQDYSEIKDLFRPGHADYTYEKKYGIRDYRGGGRSSARETAMRVAAGSIAKKYLKIQTGIVIRAYLSAMG
DIKCPFESWEEVEQNPFFCSNKNKVFQLEELIKKLKKTGDSIGAEITIIAQNVPVGFGEPVFDRLDADLAHALMSINAAK
GVEIGDGFSVVNQKGSENRDEMTPNGFKSNHCGGILGGISNGENIFLKVAFKPTSSIRQSGNTINKNNEKVKIVIKGRHD
PCVGIRAVPIAEAMVAIVLMDHLLRFRAQCAK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=352, Percent_Identity=71.875, Blast_Score=516, Evalue=1e-148,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=44.9591280653951, Blast_Score=315, Evalue=7e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BUCAP (Q9ZHE9)

Other databases:

- EMBL:   AF067228
- EMBL:   AE013218
- RefSeq:   NP_660449.1
- ProteinModelPortal:   Q9ZHE9
- SMR:   Q9ZHE9
- EnsemblBacteria:   EBBUCT00000000349
- GeneID:   1005907
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg090
- GeneTree:   EBGT00050000007958
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   BAPH198804:BUSG090-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38647; Mature: 38515

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTIGKVFRVTTFGESHGTALGCVIDGMPPGLELSSDDLQYDLNRRRPGTSRYTTQRS
CCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHH
ELDEVQILSGVFKGTTTGTSIGLVIQNKDQRSQDYSEIKDLFRPGHADYTYEKKYGIRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCC
RGGGRSSARETAMRVAAGSIAKKYLKIQTGIVIRAYLSAMGDIKCPFESWEEVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEE
SNKNKVFQLEELIKKLKKTGDSIGAEITIIAQNVPVGFGEPVFDRLDADLAHALMSINAA
CCCCCEEHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFSVVNQKGSENRDEMTPNGFKSNHCGGILGGISNGENIFLKVAFKPTSSIRQ
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHH
SGNTINKNNEKVKIVIKGRHDPCVGIRAVPIAEAMVAIVLMDHLLRFRAQCAK
CCCCCCCCCCEEEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGNTIGKVFRVTTFGESHGTALGCVIDGMPPGLELSSDDLQYDLNRRRPGTSRYTTQRS
CCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHH
ELDEVQILSGVFKGTTTGTSIGLVIQNKDQRSQDYSEIKDLFRPGHADYTYEKKYGIRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCC
RGGGRSSARETAMRVAAGSIAKKYLKIQTGIVIRAYLSAMGDIKCPFESWEEVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEE
SNKNKVFQLEELIKKLKKTGDSIGAEITIIAQNVPVGFGEPVFDRLDADLAHALMSINAA
CCCCCEEHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFSVVNQKGSENRDEMTPNGFKSNHCGGILGGISNGENIFLKVAFKPTSSIRQ
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCHHHHH
SGNTINKNNEKVKIVIKGRHDPCVGIRAVPIAEAMVAIVLMDHLLRFRAQCAK
CCCCCCCCCCEEEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9767718; 12089438