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The map label for this gene is cysJ [H]

Identifier: 77748682

GI number: 77748682

Start: 3452482

End: 3454224

Strand: Direct

Name: cysJ [H]

Synonym: XAC2948

Alternate gene names: 77748682

Gene position: 3452482-3454224 (Clockwise)

Preceding gene: 21243674

Following gene: 21243679

Centisome position: 66.71

GC content: 67.81

Gene sequence:

>1743_bases
ATGAGCAACACCACCTCACGCGTGTGGCTGGGCAACGGGCTGGCTCTGCTGGCGCTTGCGGTCATCGTCGGCTGGCTGGC
CGGCCTGCATGAGGGCGCATGGTGGAGCCCACCCACGCCGCATCGCTGGCAACTGGCAGCGCTCGGCCTGGCAATGTATC
TGGGCCTGTGCGCGGTCGTACTGCTGCGTGCCCGCAAGCGTGTCGGCGCACAACGCGCAGACGCCAGCGGCGTGTTGATC
ATCTGGGCAAGCCAGACCGGATTTGCGCGTGAGCTGGCGCAACGCAGCGTTGCCGCGCTGCAATCGGCCGGCGTCGGCGC
GCATGCGCTGCCGATCGAAGCCGTCGATAGCGGTCAACTCGCACGCGTGCCGCGGCTGCTGTGCATCGTCAGCACCACCG
GCGAAGGCGATGCGCCCGACCATGCGCAGGCCGCCGAGCGCGCCTGGCGTGCCGACCACGCGCAGGATCTGACGGCGGTG
CAGTACGCAGTGCTGGCGCTTGGCGACCGTGGTTACGCGCACTACTGCGCGTTCGGCCGACGCCTCGACGATCGCCTGCA
GGCGCGCGGCGCCACTCGCCTGTTCGAGCGCATCGAGGTCGATAACGCTGACCCCAACGCCCTGCAGCACTGGCAACGCC
GTCTGGCGGAACTGGCGCCCGCACTGGCGACGCAACCCGACTGGAGCCTGCCCACCTACACCACCTGGCAGCTACGCGAA
CGTGTCCACGTCAATCCCGGCAGTGCGGGTGCGCCGATTTACCGACTGCGCCTGACGCCATGCGATGGCGCGTTGCCGCA
GTGGAGCGCAGGCGATATCGCGGAGATCGCACCGCGTCATGCCCCGGATGCGGTCGAGTCCTGGCTGCGGCGTAACCACT
ACGATGGCGCGCAGCAGATCGACGGCCGCCCCCTGCGCGACTGGCTCGGCGGCGCGCAACTTCCCGTCGATACCGGTGCC
GCTCTCGGTATCGATGTGGGTGCCGGTGCCAGCCCCGATGCAGAAGCGGAAGCAGAAGCCGGAGTCAAAAGCGACCGAGG
TGTGGGTACGAATACAGATGCGACTACAGGCGGAGCTAGAACTGCAGGCGACAGTTCCACAATGGACGCAGAAGCAATGG
TGCGCCGCCTGGCCCCCCTGCCCCATCGCGACTATTCGCTCGCATCCATTCCCGAGGAAGGCCATGCAGAACTGCTGGTA
CGCGAGCATCGGCACGCCGACGGCAGCCTGGGGCTGGGTAGCGGCTGGCTCTGCGTCCATGCACCGATCGGCGCAGCCAT
CGCGCTGCGCTTGCGCAGCAACCCCGGCTTCCACCCACCCGCACCCGACCAGCCGATGCTGCTGATCGGCAATGGCACCG
GCATCGCCGGTCTGCGCGCGCATCTGCGTGCACGCATCGCAGCCGGCGCGCGGCGCAACTGGCTGCTGTTCGGCGAACGC
AATGCCGCGCACGACGCGCTGTATGCCGACGAGCTGCAGCAGTGGCATCAGGACGGCTGGATCGAGCGCTTGGATCTTGT
CTACTCGCGCGATCAACCACAGCGACCGCATTACGTCCAACACGCGCTGGCGGCCGCCGCCGACCGCCTGCGTCATTGGA
TCGACCAAGATGCCTGCATCTACGTCTGCGGCAGTCTGCGCGGCATGGCACCCGAACTCGACCGCACGCTGGATTGCATC
CTCGGAGCCGATGTCAGACAGGAACTGCTGGGCAGCGGGCGCTATCGCCGCGACGTGTATTGA

Upstream 100 bases:

>100_bases
ATGCGCGCAAGGCGGAACTGGCCGTGCGATTCCTGGCACGCAAGGACGGCATCCTGCTCGAATCGATGAGCCCGGCATTC
GAACGCCACCTGTCCGCGTC

Downstream 100 bases:

>100_bases
CCCATCGCACGCGGCACCGCCAAAAGCGCTCAATAAAGCGATTACGCAGGTACCCGCAGCGCGTCTGCTGCTGAAATCCG
CAACATCCCTGCTTGCGGTG

Product: sulfite reductase

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSNTTSRVWLGNGLALLALAVIVGWLAGLHEGAWWSPPTPHRWQLAALGLAMYLGLCAVVLLRARKRVGAQRADASGVLI
IWASQTGFARELAQRSVAALQSAGVGAHALPIEAVDSGQLARVPRLLCIVSTTGEGDAPDHAQAAERAWRADHAQDLTAV
QYAVLALGDRGYAHYCAFGRRLDDRLQARGATRLFERIEVDNADPNALQHWQRRLAELAPALATQPDWSLPTYTTWQLRE
RVHVNPGSAGAPIYRLRLTPCDGALPQWSAGDIAEIAPRHAPDAVESWLRRNHYDGAQQIDGRPLRDWLGGAQLPVDTGA
ALGIDVGAGASPDAEAEAEAGVKSDRGVGTNTDATTGGARTAGDSSTMDAEAMVRRLAPLPHRDYSLASIPEEGHAELLV
REHRHADGSLGLGSGWLCVHAPIGAAIALRLRSNPGFHPPAPDQPMLLIGNGTGIAGLRAHLRARIAAGARRNWLLFGER
NAAHDALYADELQQWHQDGWIERLDLVYSRDQPQRPHYVQHALAAAADRLRHWIDQDACIYVCGSLRGMAPELDRTLDCI
LGADVRQELLGSGRYRRDVY

Sequences:

>Translated_580_residues
MSNTTSRVWLGNGLALLALAVIVGWLAGLHEGAWWSPPTPHRWQLAALGLAMYLGLCAVVLLRARKRVGAQRADASGVLI
IWASQTGFARELAQRSVAALQSAGVGAHALPIEAVDSGQLARVPRLLCIVSTTGEGDAPDHAQAAERAWRADHAQDLTAV
QYAVLALGDRGYAHYCAFGRRLDDRLQARGATRLFERIEVDNADPNALQHWQRRLAELAPALATQPDWSLPTYTTWQLRE
RVHVNPGSAGAPIYRLRLTPCDGALPQWSAGDIAEIAPRHAPDAVESWLRRNHYDGAQQIDGRPLRDWLGGAQLPVDTGA
ALGIDVGAGASPDAEAEAEAGVKSDRGVGTNTDATTGGARTAGDSSTMDAEAMVRRLAPLPHRDYSLASIPEEGHAELLV
REHRHADGSLGLGSGWLCVHAPIGAAIALRLRSNPGFHPPAPDQPMLLIGNGTGIAGLRAHLRARIAAGARRNWLLFGER
NAAHDALYADELQQWHQDGWIERLDLVYSRDQPQRPHYVQHALAAAADRLRHWIDQDACIYVCGSLRGMAPELDRTLDCI
LGADVRQELLGSGRYRRDVY
>Mature_579_residues
SNTTSRVWLGNGLALLALAVIVGWLAGLHEGAWWSPPTPHRWQLAALGLAMYLGLCAVVLLRARKRVGAQRADASGVLII
WASQTGFARELAQRSVAALQSAGVGAHALPIEAVDSGQLARVPRLLCIVSTTGEGDAPDHAQAAERAWRADHAQDLTAVQ
YAVLALGDRGYAHYCAFGRRLDDRLQARGATRLFERIEVDNADPNALQHWQRRLAELAPALATQPDWSLPTYTTWQLRER
VHVNPGSAGAPIYRLRLTPCDGALPQWSAGDIAEIAPRHAPDAVESWLRRNHYDGAQQIDGRPLRDWLGGAQLPVDTGAA
LGIDVGAGASPDAEAEAEAGVKSDRGVGTNTDATTGGARTAGDSSTMDAEAMVRRLAPLPHRDYSLASIPEEGHAELLVR
EHRHADGSLGLGSGWLCVHAPIGAAIALRLRSNPGFHPPAPDQPMLLIGNGTGIAGLRAHLRARIAAGARRNWLLFGERN
AAHDALYADELQQWHQDGWIERLDLVYSRDQPQRPHYVQHALAAAADRLRHWIDQDACIYVCGSLRGMAPELDRTLDCIL
GADVRQELLGSGRYRRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=229, Percent_Identity=31.0043668122271, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI24041029, Length=241, Percent_Identity=30.2904564315353, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI40254422, Length=225, Percent_Identity=30.6666666666667, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI221316709, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI7657393, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789123, Length=545, Percent_Identity=28.6238532110092, Blast_Score=168, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17566446, Length=204, Percent_Identity=30.3921568627451, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321143, Length=234, Percent_Identity=26.4957264957265, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321832, Length=220, Percent_Identity=28.6363636363636, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI78706872, Length=239, Percent_Identity=31.3807531380753, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24583543, Length=239, Percent_Identity=31.3807531380753, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI78706876, Length=239, Percent_Identity=31.3807531380753, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17137192, Length=206, Percent_Identity=27.6699029126214, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24582192, Length=206, Percent_Identity=27.6699029126214, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 62815; Mature: 62684

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTTSRVWLGNGLALLALAVIVGWLAGLHEGAWWSPPTPHRWQLAALGLAMYLGLCAVV
CCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLRARKRVGAQRADASGVLIIWASQTGFARELAQRSVAALQSAGVGAHALPIEAVDSGQL
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
ARVPRLLCIVSTTGEGDAPDHAQAAERAWRADHAQDLTAVQYAVLALGDRGYAHYCAFGR
HHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RLDDRLQARGATRLFERIEVDNADPNALQHWQRRLAELAPALATQPDWSLPTYTTWQLRE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
RVHVNPGSAGAPIYRLRLTPCDGALPQWSAGDIAEIAPRHAPDAVESWLRRNHYDGAQQI
HEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCHHHC
DGRPLRDWLGGAQLPVDTGAALGIDVGAGASPDAEAEAEAGVKSDRGVGTNTDATTGGAR
CCCCHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
TAGDSSTMDAEAMVRRLAPLPHRDYSLASIPEEGHAELLVREHRHADGSLGLGSGWLCVH
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEE
APIGAAIALRLRSNPGFHPPAPDQPMLLIGNGTGIAGLRAHLRARIAAGARRNWLLFGER
CCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECC
NAAHDALYADELQQWHQDGWIERLDLVYSRDQPQRPHYVQHALAAAADRLRHWIDQDACI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
YVCGSLRGMAPELDRTLDCILGADVRQELLGSGRYRRDVY
EEEHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNTTSRVWLGNGLALLALAVIVGWLAGLHEGAWWSPPTPHRWQLAALGLAMYLGLCAVV
CCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLRARKRVGAQRADASGVLIIWASQTGFARELAQRSVAALQSAGVGAHALPIEAVDSGQL
HHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
ARVPRLLCIVSTTGEGDAPDHAQAAERAWRADHAQDLTAVQYAVLALGDRGYAHYCAFGR
HHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RLDDRLQARGATRLFERIEVDNADPNALQHWQRRLAELAPALATQPDWSLPTYTTWQLRE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
RVHVNPGSAGAPIYRLRLTPCDGALPQWSAGDIAEIAPRHAPDAVESWLRRNHYDGAQQI
HEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCHHHC
DGRPLRDWLGGAQLPVDTGAALGIDVGAGASPDAEAEAEAGVKSDRGVGTNTDATTGGAR
CCCCHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
TAGDSSTMDAEAMVRRLAPLPHRDYSLASIPEEGHAELLVREHRHADGSLGLGSGWLCVH
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEE
APIGAAIALRLRSNPGFHPPAPDQPMLLIGNGTGIAGLRAHLRARIAAGARRNWLLFGER
CCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECC
NAAHDALYADELQQWHQDGWIERLDLVYSRDQPQRPHYVQHALAAAADRLRHWIDQDACI
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
YVCGSLRGMAPELDRTLDCILGADVRQELLGSGRYRRDVY
EEEHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA