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The map label for this gene is dapE

Identifier: 21243679

GI number: 21243679

Start: 3456939

End: 3458432

Strand: Direct

Name: dapE

Synonym: XAC2952

Alternate gene names: NA

Gene position: 3456939-3458432 (Clockwise)

Preceding gene: 77748682

Following gene: 21243680

Centisome position: 66.79

GC content: 66.6

Gene sequence:

>1494_bases
ATGGACAGCGCCAAGATCGACCAATTCGTCAGCGACACCTGGGACCGCGAGATCGTCCCGCAATTGGTCGATTACATTCG
CATCCCCAATAAATCGCCGATGTTCGACGCCGATTGGGTCGCGCACGGCTACATGGAGCAGGCGGTCACCCTGATGGAAA
CCTGGGCGCGCGCGCAGGCCATCGAGGGCATGCAGGTCGAGGTGGTGCGCCTGGAAGGCCGCACGCCGTTGATCTTCATC
GAGATTCCGGCAACCGGTGCCGAATCGGGCGACGACACCGTGCTGCTGTACGGCCACCTGGACAAGCAGCCGGAAATGAC
CGGCTGGGATGCGGACCTCGGCCCATGGGAGCCGGTGCTGCGCGACGACAAGTTGTACGGGCGCGGTGGCGCCGACGATG
GTTACGCGATCTTCGGTTTGCTGGCGGCGGTACTGGCGCTGCGCACCCAGGGCCTGCCGCATGCGCGCTGCGTGGTGCTG
ATCGAGGCCTGCGAGGAATCCGGCAGCTACGACCTGCCGGCCTACGTCGACCATCTGGCCGCACGCATCGGCAAGCCATC
GCTGGTGGTGTGCCTGGATTCGGGCTGCGGCAACTATGAGCAGCTGTGGTGCACCACCTCGCTGCGCGGGCTGACCGGCG
GCAACCTGAGCGTGAAGGTGCTGGAGGAAGGCGTGCATTCGGGCGATGCCTCCGGCGTAGTGCCGTCCAGCTTCCGCCTG
CTGCGCCAGTTGCTGTCGCGGATCGAGGACGAAGCCAGCGGCCGCATCCTGCTGGACGGGCTGCATGTGCAGGTGCCAGC
CGAACGGCTGGCGCAGGCCAAGGCCGCTGCGGCGACGCTGGATACCGCCATCTTTGACAAGTTCCCGATGGTCGAGGGCC
TGGTGCCGATGCACGACGACCTCACCGAGCTGGTGTTGAACCGCACCTGGCGCCCGGCGTTGTCGATCACCGGTGTGGAT
GGCATGCCGCCGCTGGCGTCGGCCGGCAACGTGCTGCGTCCGCAGACCGCGGTGAAGCTGTCGCTGCGTCTGCCGCCAAC
CGCCGACGGCAAGGCCTGTGGCGAACTGCTGAAAGAGGCCTTGCTGCGCGACCCACCCAACGGCGCACAGGTGACGCTGG
AACTGGAAAAGGCCTCGTCGGGCTGGAATGCGCCCGAGATGGCGCCATGGCTGGCAAAAGCCATCGACGACGCCAGCCTG
GCGTTCTTCGACAAGCCGGCGATGTACATGGGCGAAGGCGGCTCGATCCCGTTCATGGGCATGCTGGGCGAGAAGTTTCC
CGGCGCACAGTTCATGATCACCGGCGTGCTCGGCCCGCATTCCAATGCGCATGGCCCCAACGAGTTCCTGCACATCCCGA
TGGGCAAGCGGGTCACGGCCTGCGTGTCCAAGGTGATCGCCGAGCACCACGCCGCCTGCCTGCGCGGCGAGACCAGCGGC
TCGCCGGTGGCGGCCGATAGCGGCACCCGTCATGGTGGGCATGGTTGCTGTTGA

Upstream 100 bases:

>100_bases
TTTTCACACAGCCGGTGAACTGCGCGTCGCCTTGTAGGGAAATACCTACCCCCCGAGGCGGGCGTAGAATGTCCGGCTAC
GTCATGCATTCGGAGTCTCC

Downstream 100 bases:

>100_bases
GTTGTGGCTTCATCGATGCGCGCGGTTGGCGCGCATCGATGTCATGAGAGGTCGGTCTGCGTTTTCAAATGAGGATTGGT
GCGGGTGCGCCTTGGTCGGC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: Peptidase; M20/M25/M40 Family Peptidase; Succinyl-Diaminopimelate Desuccinylase; Peptidase Family; ArgE/DapE/Acy1 Family Protein; M20 Family Peptidase; Zinc Metallopeptidase; Peptidase Dimerization Domain Protein; N-Acyl-L-Amino Acid Amidohydrolase; Peptidase Dimerisation Domain-Containing Protein; Peptidase Or Deacetlylase Family Protein; Acetylornithine Deacetylase ArgE; Beta-Ala-His Dipeptidase; Metallopeptidase; Thiol Dipeptidase; Peptidase Dimerisation Domain Protein

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MDSAKIDQFVSDTWDREIVPQLVDYIRIPNKSPMFDADWVAHGYMEQAVTLMETWARAQAIEGMQVEVVRLEGRTPLIFI
EIPATGAESGDDTVLLYGHLDKQPEMTGWDADLGPWEPVLRDDKLYGRGGADDGYAIFGLLAAVLALRTQGLPHARCVVL
IEACEESGSYDLPAYVDHLAARIGKPSLVVCLDSGCGNYEQLWCTTSLRGLTGGNLSVKVLEEGVHSGDASGVVPSSFRL
LRQLLSRIEDEASGRILLDGLHVQVPAERLAQAKAAAATLDTAIFDKFPMVEGLVPMHDDLTELVLNRTWRPALSITGVD
GMPPLASAGNVLRPQTAVKLSLRLPPTADGKACGELLKEALLRDPPNGAQVTLELEKASSGWNAPEMAPWLAKAIDDASL
AFFDKPAMYMGEGGSIPFMGMLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVSKVIAEHHAACLRGETSG
SPVAADSGTRHGGHGCC

Sequences:

>Translated_497_residues
MDSAKIDQFVSDTWDREIVPQLVDYIRIPNKSPMFDADWVAHGYMEQAVTLMETWARAQAIEGMQVEVVRLEGRTPLIFI
EIPATGAESGDDTVLLYGHLDKQPEMTGWDADLGPWEPVLRDDKLYGRGGADDGYAIFGLLAAVLALRTQGLPHARCVVL
IEACEESGSYDLPAYVDHLAARIGKPSLVVCLDSGCGNYEQLWCTTSLRGLTGGNLSVKVLEEGVHSGDASGVVPSSFRL
LRQLLSRIEDEASGRILLDGLHVQVPAERLAQAKAAAATLDTAIFDKFPMVEGLVPMHDDLTELVLNRTWRPALSITGVD
GMPPLASAGNVLRPQTAVKLSLRLPPTADGKACGELLKEALLRDPPNGAQVTLELEKASSGWNAPEMAPWLAKAIDDASL
AFFDKPAMYMGEGGSIPFMGMLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVSKVIAEHHAACLRGETSG
SPVAADSGTRHGGHGCC
>Mature_497_residues
MDSAKIDQFVSDTWDREIVPQLVDYIRIPNKSPMFDADWVAHGYMEQAVTLMETWARAQAIEGMQVEVVRLEGRTPLIFI
EIPATGAESGDDTVLLYGHLDKQPEMTGWDADLGPWEPVLRDDKLYGRGGADDGYAIFGLLAAVLALRTQGLPHARCVVL
IEACEESGSYDLPAYVDHLAARIGKPSLVVCLDSGCGNYEQLWCTTSLRGLTGGNLSVKVLEEGVHSGDASGVVPSSFRL
LRQLLSRIEDEASGRILLDGLHVQVPAERLAQAKAAAATLDTAIFDKFPMVEGLVPMHDDLTELVLNRTWRPALSITGVD
GMPPLASAGNVLRPQTAVKLSLRLPPTADGKACGELLKEALLRDPPNGAQVTLELEKASSGWNAPEMAPWLAKAIDDASL
AFFDKPAMYMGEGGSIPFMGMLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVSKVIAEHHAACLRGETSG
SPVAADSGTRHGGHGCC

Specific function: Unknown

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI271398239, Length=387, Percent_Identity=27.390180878553, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI21071039, Length=422, Percent_Identity=27.9620853080569, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17563146, Length=404, Percent_Identity=27.7227722772277, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193211059, Length=425, Percent_Identity=25.4117647058824, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321159, Length=382, Percent_Identity=26.4397905759162, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585880, Length=392, Percent_Identity=29.8469387755102, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53307; Mature: 53307

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSAKIDQFVSDTWDREIVPQLVDYIRIPNKSPMFDADWVAHGYMEQAVTLMETWARAQA
CCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IEGMQVEVVRLEGRTPLIFIEIPATGAESGDDTVLLYGHLDKQPEMTGWDADLGPWEPVL
CCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHH
RDDKLYGRGGADDGYAIFGLLAAVLALRTQGLPHARCVVLIEACEESGSYDLPAYVDHLA
CCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEEEEHHCCCCCCCHHHHHHHH
ARIGKPSLVVCLDSGCGNYEQLWCTTSLRGLTGGNLSVKVLEEGVHSGDASGVVPSSFRL
HHCCCCEEEEEECCCCCCHHEEEEECCCCCCCCCCEEEEEEHHCCCCCCCCCCCHHHHHH
LRQLLSRIEDEASGRILLDGLHVQVPAERLAQAKAAAATLDTAIFDKFPMVEGLVPMHDD
HHHHHHHHHHCCCCEEEEECEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHH
LTELVLNRTWRPALSITGVDGMPPLASAGNVLRPQTAVKLSLRLPPTADGKACGELLKEA
HHHHHHCCCCCCCEEEECCCCCCCHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
LLRDPPNGAQVTLELEKASSGWNAPEMAPWLAKAIDDASLAFFDKPAMYMGEGGSIPFMG
HHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCHH
MLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVSKVIAEHHAACLRGETSG
HCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SPVAADSGTRHGGHGCC
CCEECCCCCCCCCCCCC
>Mature Secondary Structure
MDSAKIDQFVSDTWDREIVPQLVDYIRIPNKSPMFDADWVAHGYMEQAVTLMETWARAQA
CCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IEGMQVEVVRLEGRTPLIFIEIPATGAESGDDTVLLYGHLDKQPEMTGWDADLGPWEPVL
CCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHH
RDDKLYGRGGADDGYAIFGLLAAVLALRTQGLPHARCVVLIEACEESGSYDLPAYVDHLA
CCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEEEEHHCCCCCCCHHHHHHHH
ARIGKPSLVVCLDSGCGNYEQLWCTTSLRGLTGGNLSVKVLEEGVHSGDASGVVPSSFRL
HHCCCCEEEEEECCCCCCHHEEEEECCCCCCCCCCEEEEEEHHCCCCCCCCCCCHHHHHH
LRQLLSRIEDEASGRILLDGLHVQVPAERLAQAKAAAATLDTAIFDKFPMVEGLVPMHDD
HHHHHHHHHHCCCCEEEEECEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHH
LTELVLNRTWRPALSITGVDGMPPLASAGNVLRPQTAVKLSLRLPPTADGKACGELLKEA
HHHHHHCCCCCCCEEEECCCCCCCHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
LLRDPPNGAQVTLELEKASSGWNAPEMAPWLAKAIDDASLAFFDKPAMYMGEGGSIPFMG
HHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCHH
MLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVSKVIAEHHAACLRGETSG
HCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SPVAADSGTRHGGHGCC
CCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA