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The map label for this gene is apbE [H]

Identifier: 21243674

GI number: 21243674

Start: 3451565

End: 3452485

Strand: Direct

Name: apbE [H]

Synonym: XAC2947

Alternate gene names: 21243674

Gene position: 3451565-3452485 (Clockwise)

Preceding gene: 21243673

Following gene: 77748682

Centisome position: 66.69

GC content: 68.51

Gene sequence:

>921_bases
ATGGGCACCACCTGGAGCGTGAAGCTGGTGGCGCCGCGCGGACGCGATCTGCACCCCTTGCATGCGTGCATCCAGGCCGC
GCTGGACCGCGTGGTCGCGCAGATGAGTACCTGGAAGGCCGATTCGGATATCAGCCGTTACAACCGCGCACCGGCAGGCA
GCTGGCACCACCTGCCGGACGAATTCCACGCAGTGCTGAGCGCAGCATTGGAGTTCGCACAGGCCAGCGAGGGTGCCTTC
GATCCCACCGTCGGCCCGATGGTCGAGCTATGGGGCTTTGGCGCTTCCGGCACGCGCCAGCGCGTGCCGGAAGCGCAGGC
GATCGCATTGGCGAGCCTGCGTTGCGGCTGGCAACGCCTGCAGCTGGATGGCAGGCGGGTGCTGCAGCCGGGCGCAGCGG
CGCTGGATCTGTCCGGCATCGCCAAGGGCTTCGGTGTGGACTGCGTGCATCGCGCATTGCTGCAGTCGGGTATCGACAGT
GCATTGATCGAGGTCGGCGGCGAATTGTTCGGTTACGGACGCAAGCCCGATGCCAGCGCGTGGCGCGTGTTGGTCGAATC
CGCCCCCGACGAAGACGCCGGCAGCGCGCTGCCACCACGCGTGCTGGCGCTGGACGGCCTGGCGGTCGCCACCTCCGGCG
ATCGCTGGCACCGCTTCGATGCCGACGGCACACGCTATACGCACACCCTCGACCCACGCACCGGCGCGCCCGTTCCGCAT
GCCCCTGCGGCGGTCACCGTACTCGCGCCCGATGCGATGCAGGCCGATGCCTGGGCCACCGCGATGACCGTGCTTGGCGC
CGATGCCGGTCTTGCCCATGCGCGCAAGGCGGAACTGGCCGTGCGATTCCTGGCACGCAAGGACGGCATCCTGCTCGAAT
CGATGAGCCCGGCATTCGAACGCCACCTGTCCGCGTCATGA

Upstream 100 bases:

>100_bases
CGCACACAGCGTGCGTCCTGCCGCCCCATCCTCATAAGACCCGTCCATGCCCGCATCGTCTTCCGCCGACCACGCCGTTG
CCACGCTCGGCGGCCGCAGC

Downstream 100 bases:

>100_bases
GCAACACCACCTCACGCGTGTGGCTGGGCAACGGGCTGGCTCTGCTGGCGCTTGCGGTCATCGTCGGCTGGCTGGCCGGC
CTGCATGAGGGCGCATGGTG

Product: thiamine biosynthesis lipoprotein ApbE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MGTTWSVKLVAPRGRDLHPLHACIQAALDRVVAQMSTWKADSDISRYNRAPAGSWHHLPDEFHAVLSAALEFAQASEGAF
DPTVGPMVELWGFGASGTRQRVPEAQAIALASLRCGWQRLQLDGRRVLQPGAAALDLSGIAKGFGVDCVHRALLQSGIDS
ALIEVGGELFGYGRKPDASAWRVLVESAPDEDAGSALPPRVLALDGLAVATSGDRWHRFDADGTRYTHTLDPRTGAPVPH
APAAVTVLAPDAMQADAWATAMTVLGADAGLAHARKAELAVRFLARKDGILLESMSPAFERHLSAS

Sequences:

>Translated_306_residues
MGTTWSVKLVAPRGRDLHPLHACIQAALDRVVAQMSTWKADSDISRYNRAPAGSWHHLPDEFHAVLSAALEFAQASEGAF
DPTVGPMVELWGFGASGTRQRVPEAQAIALASLRCGWQRLQLDGRRVLQPGAAALDLSGIAKGFGVDCVHRALLQSGIDS
ALIEVGGELFGYGRKPDASAWRVLVESAPDEDAGSALPPRVLALDGLAVATSGDRWHRFDADGTRYTHTLDPRTGAPVPH
APAAVTVLAPDAMQADAWATAMTVLGADAGLAHARKAELAVRFLARKDGILLESMSPAFERHLSAS
>Mature_305_residues
GTTWSVKLVAPRGRDLHPLHACIQAALDRVVAQMSTWKADSDISRYNRAPAGSWHHLPDEFHAVLSAALEFAQASEGAFD
PTVGPMVELWGFGASGTRQRVPEAQAIALASLRCGWQRLQLDGRRVLQPGAAALDLSGIAKGFGVDCVHRALLQSGIDSA
LIEVGGELFGYGRKPDASAWRVLVESAPDEDAGSALPPRVLALDGLAVATSGDRWHRFDADGTRYTHTLDPRTGAPVPHA
PAAVTVLAPDAMQADAWATAMTVLGADAGLAHARKAELAVRFLARKDGILLESMSPAFERHLSAS

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=309, Percent_Identity=32.0388349514563, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 32485; Mature: 32354

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTWSVKLVAPRGRDLHPLHACIQAALDRVVAQMSTWKADSDISRYNRAPAGSWHHLPD
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCH
EFHAVLSAALEFAQASEGAFDPTVGPMVELWGFGASGTRQRVPEAQAIALASLRCGWQRL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHCHHHH
QLDGRRVLQPGAAALDLSGIAKGFGVDCVHRALLQSGIDSALIEVGGELFGYGRKPDASA
HCCCCHHCCCCCCCEEHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCHHHHCCCCCCCHHH
WRVLVESAPDEDAGSALPPRVLALDGLAVATSGDRWHRFDADGTRYTHTLDPRTGAPVPH
HHHHHHCCCCCCCCCCCCCCEEEECCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC
APAAVTVLAPDAMQADAWATAMTVLGADAGLAHARKAELAVRFLARKDGILLESMSPAFE
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
RHLSAS
HHCCCC
>Mature Secondary Structure 
GTTWSVKLVAPRGRDLHPLHACIQAALDRVVAQMSTWKADSDISRYNRAPAGSWHHLPD
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCH
EFHAVLSAALEFAQASEGAFDPTVGPMVELWGFGASGTRQRVPEAQAIALASLRCGWQRL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHCHHHH
QLDGRRVLQPGAAALDLSGIAKGFGVDCVHRALLQSGIDSALIEVGGELFGYGRKPDASA
HCCCCHHCCCCCCCEEHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCHHHHCCCCCCCHHH
WRVLVESAPDEDAGSALPPRVLALDGLAVATSGDRWHRFDADGTRYTHTLDPRTGAPVPH
HHHHHHCCCCCCCCCCCCCCEEEECCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC
APAAVTVLAPDAMQADAWATAMTVLGADAGLAHARKAELAVRFLARKDGILLESMSPAFE
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
RHLSAS
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]